The integration, analysis and visualization of the big omics data are critical for addressing a broad spectrum of biological questions. One of the most frequently conducted procedures is enrichment analysis, which sta...The integration, analysis and visualization of the big omics data are critical for addressing a broad spectrum of biological questions. One of the most frequently conducted procedures is enrichment analysis, which statistically tests whether individual functional an- notations of Gent Ontology （GO） or Kyoto Encyclopedia of Genes and Genomes （KEGG） are significantly over-or under-represented in an ＂interesting＂ gene or protein list against the reference set （Tavazoie et al., 1999）.展开更多
基金supported by the Special Project on Precision Medicine under the National Key R&D Program (2017YFC0906600)the Natural Science Foundation of China (No. 31671360)
文摘The integration, analysis and visualization of the big omics data are critical for addressing a broad spectrum of biological questions. One of the most frequently conducted procedures is enrichment analysis, which statistically tests whether individual functional an- notations of Gent Ontology （GO） or Kyoto Encyclopedia of Genes and Genomes （KEGG） are significantly over-or under-represented in an ＂interesting＂ gene or protein list against the reference set （Tavazoie et al., 1999）.
