Ricinine(3-cyano-4-methoxy-N-methyl-2-pyridone)is an alkaloid present in leaves and seeds of castor plant i.e.Ricinus communis.It can cause vomiting,convulsions,hypotension,liver and kidney damage and several other co...Ricinine(3-cyano-4-methoxy-N-methyl-2-pyridone)is an alkaloid present in leaves and seeds of castor plant i.e.Ricinus communis.It can cause vomiting,convulsions,hypotension,liver and kidney damage and several other complications in human.Ricinine presents mainly in young plant and it is the only cyano-substituted pyridine compounds occurred naturally.Ricinine also found in some other plants such as Piper nigrum,Discocleidion rufescens,Aparisthmium cordatum and Nicotiana tabacum.Accidental and intended Ricinus communis intoxications in humans and animals have been known for centuries.In the present review,we summarize the information regarding its medicinal uses,pharmacological activities,analytical techniques and intended and unintended poisoning cases in humans and animals.This review will be beneficial for the researcher in the field of herbal medicine and other allied sciences.展开更多
基金Supported by University Grant Commision,New Delhi,India with grant No.:IT/DEV/08-09/3252/L.
文摘Ricinine(3-cyano-4-methoxy-N-methyl-2-pyridone)is an alkaloid present in leaves and seeds of castor plant i.e.Ricinus communis.It can cause vomiting,convulsions,hypotension,liver and kidney damage and several other complications in human.Ricinine presents mainly in young plant and it is the only cyano-substituted pyridine compounds occurred naturally.Ricinine also found in some other plants such as Piper nigrum,Discocleidion rufescens,Aparisthmium cordatum and Nicotiana tabacum.Accidental and intended Ricinus communis intoxications in humans and animals have been known for centuries.In the present review,we summarize the information regarding its medicinal uses,pharmacological activities,analytical techniques and intended and unintended poisoning cases in humans and animals.This review will be beneficial for the researcher in the field of herbal medicine and other allied sciences.
