Rotating magnetic field inhibits Aβ protein aggregation and alleviates cognitive impairment in Alzheimer’s disease mice

Amyloid beta(Aβ)monomers aggregate to form fibrils and amyloid plaques,which are critical mechanisms in the pathogenesis of Alzheimer’s disease(AD).Given the important role of Aβ1-42 aggregation in plaque formation,leading to brain lesions and cognitive impairment,numerous studies have aimed to reduce Aβaggregation and slow AD progression.The diphenylalanine(FF)sequence is critical for amyloid aggregation,and magnetic fields can affect peptide alignment due to the diamagnetic anisotropy of aromatic rings.In this study,we examined the effects of a moderate-intensity rotating magnetic field(RMF)on Aβaggregation and AD pathogenesis.Results indicated that the RMF directly inhibited Aβamyloid fibril formation and reduced Aβ-induced cytotoxicity in neural cells in vitro.Using the AD mouse model APP/PS1,RMF restored motor abilities to healthy control levels and significantly alleviated cognitive impairments,including exploration and spatial and non-spatial memory abilities.Tissue examinations demonstrated that RMF reduced amyloid plaque accumulation,attenuated microglial activation,and reduced oxidative stress in the APP/PS1 mouse brain.These findings suggest that RMF holds considerable potential as a non-invasive,high-penetration physical approach for AD treatment.

Effect of power supply parameters on discharge characteristics and sterilization efficiency of magnetically driven rotating gliding arc

Plasma sterilization is a new generation of high-tech sterilization method that is fast,safe,and pollution free.It is widely used in medical,food,and environmental protection fields.Home air sterilization is an emerging field of plasma application,which puts higher requirements on the miniaturization,operational stability,and operating cost of plasma device.In this study,a novel magnetically driven rotating gliding arc(MDRGA)discharge device was used to sterilize Lactobacillus fermentation.Compared with the traditional gas-driven gliding arc,this device has a simple structure and a more stable gliding arc.Simulation using COMSOL Multiphysics showed that adding permanent magnets can form a stable magnetic field,which is conducive to the formation of gliding arcs.Experiments on the discharge performance,ozone concentration,and sterilization effect were conducted using different power supply parameters.The results revealed that the MDRGA process can be divided into three stages:starting,gliding,and extinguishing.Appropriate voltage was the key factor for stable arc gliding,and both high and low voltages were not conducive to stable arc gliding and ozone production.In this experimental setup,the sterilization effect was the best at 6.6 kV.A high modulation duty ratio was beneficial for achieving stable arc gliding.However,when the duty ratio exceeded a certain value,the improvement in the sterilization effect was slow.Therefore,considering the sterilization effect and energy factors comprehensively,we chose 80%as the optimal modulation duty ratio for this experimental device.

INFLUENCE OF MAGNETIZATION ROTATION ON MARTENSITE REORIENTATION IN MAGNETIC SHAPE MEMORY ALLOY

A large field-induced strain of magnetic shape memory alloy is developed by the martensite variant reorientation. It is widely recognized that the martensite reorientation in a magnetic shape memory alloy （MSMA） can develop if the magnetic field is large enough. However, it has been shown in the literature that the magnetization rotation may block variant reorientation via energy minimization approach. In this paper, based on a micromechanicat model associated with the thermodynamic theory, authors show that there are some limits for the martensite reorientation, which is hindered by the magnetization rotation. Some useful conclusions are obtained.

Evolution of magnetically rotating arc into large area arc plasma

An arc channel tends to shrink due to its conductivity increasing with the increase of temperature. In this study, to generate large area arc plasma, we construct a magnetically rotating arc plasma generator, which mainly consists of a lanthanide tungsten cathode （13 mm in diameter）, a concentric cylindrical graphite anode chamber （60 nun in diameter） and a solenoid coil for producing an axial magnet field. By controlling the cold gas flow, the magnetically rotating arc evolves from constricted mode to diffuse mode, which almost fills the whole arc chamber cross section. Results show that the diffuse arc plasma has better uniformity and stability. The formation mechanism of large area arc plasma is discussed in this paper.

Heisenberg Model in a Rotating Magnetic Field

We study the Hcisenberg moder under the influence of a rotating magnetic field. By using a time- dependent unitary transformation, the time evolution operator for the Schrodinger equation is obtained, which involves no chronological product. The spin vectors (mean values of the spin operators) are obtained as explicit functions of time in the most general case. A series of cyclic solutions are presented. The nonadiabatic geometric phases of these cyclic solutions are caleulated, and are expressed in terms of the solid angle subtended by the closed trace of thc total spin vector, as well as in terms of those of the individual spins.

Effect of compound treatment of rotating magnetic field and Al-5Ti-1B refiner on microstructure and properties of Al-5Cu alloy

The Al-5Cu alloys were prepared by different treatment methods,including adding a refiner Al-5Ti-1B,exerting a rotating magnetic field(RMF),and compound treatment of both refiner and RMF.The effects of treatment methods on the microstructure,properties,and solid solubility of the Al-5Cu alloy were investigated.The optimal magnetic field parameters and addition amount of refiner were confirmed by experiment.Results show that either RMF or adding refiner Al-5Ti-1B alone can refine the grain size,and the refining effect can be further improved by a compound refining treatment with optimized magnetic field parameters(120 A current and 8 Hz frequency) and 1.0wt.% Al-5Ti-1B refiner(RMF*+Al-5Ti-1B*).The average grain size is decreased to 68.1 μm,which is 60.8%,21.1%,and 83.5% lower than that of the alloy treated by the optimized rotating magnetic field,the Al-5Ti-1B refiner,and the alloy without any treatment,respectively.The tensile strength and elongation of the alloy reach 232.5 MPa and 18.6%,respectively,which are obviously higher than those of the alloys treated by rotating magnetic field,Al-5Ti-1B refiner,and the alloy without any treatment,respectively.Additionally,the solid solubility of the alloy is also obviously improved compared to the alloys treated by other methods.

EFFECT OF ROTATING MAGNETIC FIELD ONMACROSTRUCTURE OF A CENTRIFUGALCASTING Al-1%Cu ALLOY

Rotating electromagnetic field is applied to the centrifugal casting, the macrostructure of centrifugal casting Al-1%Cu alloy stirred with driving or backing magnetic field are both examined. It is shown that both kinds of electromagnetic filed can enforce the columnar-equiaxed transition, the driving one decrease the tendency of porosity occurring due to the increase in the bulk liquid pressure. Stirring with braking electromagnetic field produces the mixture of outer fine grains and inner coarse grains in the casting, this is analyzed to be contributed to the differences both in electric conductivity and density between the crystal and the melt, as well as skin effects.

The effect of toroidal field on the rotating magnetic field current drive in rotamak plasmas

A rotamak is one kind of compact spherically shaped magnetic-confinement device. In a rotamak the plasma current is driven by means of rotating magnetic field （RMF）. The driven current can reverse the original equilibrium field and generate a field-reversed-configuration. In a conventional rotamak, a toroidal field （TF） is not necessary for the RMF to drive plasma current, but it was found that the present of an additional TF can influence the RMF current drive. In this paper the effect of TF on the RMF current drive in a rotamak are investigated in some detail. The experimental results show that addition of TF increases the RMF driven current greatly and enhances the RMF penetration dramatically. Without TF, the RMF can only penetrate into plasma in the edge region. When a TF is added, the RMF can reach almost the whole plasma region. This is an optimal strength of toroidal magnetic field for getting maximum plasma current when Bv and radio frequency generator power are fixed. Besides driving current, the RMF generates high harmonic fields in rotamak plasma. The effect of TF on the harmonic field spectra are also reported.

Electric-field-induced in-plane effective 90°magnetization rotation in Co2FeAl/PMN-PT structure

The in-plane effective 90°magnetization rotation of Co_(2) FeAl thin film grown on PMN-PT substrate induced by the electric field is investigated at room temperature.The magnetic hysteresis loops under different positive and negative electric fields are obtained,which reveals remanent magnetization can be mediated by the electric field.Moreover,under positive electric fields,the obvious 90°magnetization rotation can be observed,while remanent magnetization is nearly unchanged under negative electric fields.The result is consistent with the electric field dependence of effective magnetic field,which can be attributed to the piezostrain effect in Co_(2) FeAl/PMN-PT structure.In addition,the piezostrain-mediated 90°magnetization rotation can be demonstrated by the result of resonance field changing with electric field in the measurement of ferromagnetic resonance,which is promising for the design of future multiferroic devices.

Statistical study of co-rotating interaction region properties with STEREO and ACE observations

We analyzed the data on co-rotating interaction regions （CIRs） measured by the Advanced Composition Explorer （ACE） and Solar TErrestrial RElations Observatory （STEREO） from 2007 to 2010. The CIRs were observed by STEREO B （STB）, ACE and STEREOA （STA） one after another, and a total of 28 CIRs were identified in this work. Since the same characteristics of CIRs were detected by these three spacecraft at three different locations and times, these data can help us to study the evolutions of CIRs. For a single event, the properties of CIRs observed by the three spacecraft were quite different and could be explained by spatial or temporal variations. For all these 28 CIRs, STA and STB observed similar mean parameters, such as peak magnetic field strength （offset 11%）, peak and change in solar wind speed （offset 3% and 10% respectively）, peak proton temperature （offset 14%） and peak perpendicular pressure （offset 15%）. Surprisingly, STA detected much higher （41%） peak density of protons than STB.

Study on Metal Detection with an Electromagnetic Induction Probe Utilizing a Rotating Magnetic Field

The present paper describes an investigation conducted on metal detectors installed with a scanning probe.The authors applied a rotating magnetic field probe to metal detection.The rotating magnetic field probe is comprised of two vertically placed rectangular exciting coils and a circular detecting coil.The experimental results confirmed that the probe can detect metal objects and provide more information about their shape,direction,and electromagnetic characteristics than conventional metal detector probes.A two-dimensional signal display shows a low-resolution image of the metal object and the signal phase indicates the object’s direction and electromagnetic characteristics.The experimental results show that excellent reconstruction of the surface shapes of metal objects can be obtained for both magnetic and nonmagnetic metals under present conditions.There is also the potential for the approximate shape of a metal object to be estimated from the reconstructed image.

Movement behavior and separation of Al_(2)O_(3)from Al melt under rotating magnetic field

The effect of a rotating magnetic field(RMF)on the distribution of Al_(2)O_(3)particles with an Al melt was studied by means of simulation and experiment.The results show that Al_(2)O_(3)particles(diameter of 1-10μm,1wt.%)are significantly agglomerated at the top of ingots when subjected to an RMF,and their distribution is influenced by both the intensity and the duration of RMF application.The optimal separation efficiency is achieved with the magnetic intensity of 12 mT for 120 s.The number of the particles at the bottom and the middle decreases by 64.5%and 69.7%,respectively,while that at the top increases by 242.5%compared to the condition without an RMF.However,if further increase the intensity or the duration of RMF,it can induce turbulent flows that draw some of the separated Al_(2)O_(3)particles back into the melt,reducing separation efficiency.The calculation results show that as the magnetic intensity increases from 6 mT to 18 mT,the velocity difference between the particles and the Al melt flow quadruples,increasing from 0.013 m·s^(-1)to 0.066 m·s^(-1).Driven by this velocity difference,centrifugal motion,and secondary circulation,Al_(2)O_(3)particles tend to migrate upwards within the melt,facilitating the separation of impurity particles and enhancing the purity of the melt.

Current–voltage characteristics of hydrogen DC plasma torches with different sizes in an external axial magnetic field

Current-voltage （l-V） characteristics of hydrogen DC plasma torches with different sizes in an external axial magnetic field under atmospheric pressure are reported. Three anodes with different diameters are adopted in a 50-kW torch： 25 mm, 30 mm, and 35 nun, respectively. Two different diameters of anodes, that is, 100 mm and 130 mm, are adopted in a 1-MW plasma torch. The arc voltage shows a negative trend with the increase of arc current under the operating regimes. On the contrary, arc voltage shows a positive trend as the flow rate of carder gas increases, and a similar trend is found with increasing the external magnetic flux density. A similarity formula is constructed to correlate the experimental data of the torches mentioned above. Linear fitting shows that the Pearson correlation coefficient is 0.9958.

Unifying neutron star sub-populations in the supernova fallback accretion model

We employ the supernova fallback disk model to simulate the spin evolution of isolated young neutron stars(NSs). We consider the submergence of the NS magnetic fields during the supercritical accretion stage and its succeeding reemergence. It is shown that the evolution of the spin periods and the magnetic fields in this model is able to account for the relatively weak magnetic fields of central compact objects and the measured braking indices of young pulsars. For a range of initial parameters, evolutionary links can be established among various kinds of NS sub-populations including magnetars, central compact objects and young pulsars. Thus, the diversity of young NSs could be unified in the framework of the supernova fallback accretion model.

Novel inspection of welded joint microstructure using magneto-optical imaging technology

A novel method for measuring differences of microstructure by advanced use of the Faraday magneto-optical effect is proposed. Two groups of YAG laser welds on Q235 have been investigated in order to compare MO imaging and traditional methods. Microstructure images have been compared with MO images, and MO diagrams display different colors and gray scales for the base metal, the weld zone, and the heat affected zone. Experimental results indicate that the welded joint microstructure can be inspected by MO imaging without metallographic preparation.

The kinematics of an untwisting solar jet in a polar coronal hole observed by SDO/AIA

Using the multi-wavelength data from the Atmospheric Imaging Assembly （AIA） onboard the Solar Dynamics Observatory （SDO） spacecraft, we study a jet occurring in a coronal hole near the northern pole of the Sun. The jet presented distinct upward helical motion during ejection. By tracking six identified moving features （MFs） in the jet, we found that the plasma moved at an approximately constant speed along the jet＇s axis. Meanwhile, the MFs made a circular motion in the plane transverse to the axis. Inferred from linear and trigonometric fittings to the axial and transverse heights of the six tracks, the mean values of the axial velocities, transverse velocities, angular speeds, rotation periods, and rotation radii of the jet are 114 km s-1, 136 km s-1, 0.81° s-1, 452 s and 9.8 × 10^3 km respectively. As the MFs rose, the jet width at the corresponding height increased. For the first time, we derived the height variation of the longitudinal magnetic field strength in the jet from the assumption of magnetic flux conservation. Our results indicate that at heights of 1 × 10^4 -7 × 10^4 km from the base of the jet, the flux density in the jet decreases from about 15 to 3 G as a function of B = 0.5（R/R） - 1）-0.84 （G）. A comparison was made with other results in previous studies.

Parameter analysis for a nuclear magnetic resonance gyroscope based on ^(133)Cs–^(129)Xe/^(131)Xe

We theoretically investigate several parameters for the nuclear magnetic resonance gyroscope based on ^（133）C_（s–）^（129）Xe/^（131）Xe. For a cell containing a mixture of ^（133）Cs at saturated pressure, we investigate the optimal quenching gas（N_2） pressure and the corresponding pump laser intensity to achieve 30% ^（133）Cs polarization at the center of the cell when the static magnetic field B0 is 5 μT with different ^（129）Xe/^（131）Xe pressure. The effective field produced by spin-exchange polarized ^（129）Xe or ^（131）Xe sensed by ^（133）Cs can also be discussed in different^（129）Xe/^（131）Xe pressure conditions. Furthermore,the relationship between the detected signal and the probe laser frequency is researched. We obtain the optimum probe laser detuning from the D2（6~2S_（1/2）→ 6~2P_（3/2）） resonance with different ^（129）Xe/^（131）Xe pressure owing to the pressure broadening.

Determining the sign of g factor via time-resolved Kerr rotation spectroscopy with a rotatable magnetic field

Time-resolved Kerr rotation spectroscopy is used to determine the sign of the g factor of carriers in a semiconductor material, with the help of a rotatable magnetic field in the plane of the sample. The spin precession signal of carriers at a fixed time delay is measured as a function of the orientation of the magnetic field with a fixed strength B. The signal has a sine-like form and its phase determines the sign of the g factor of carriers. As a natural extension of previous methods to measure the （time-resolved） photoluminescence or time-resolved Kerr rotation signal as a function of the magnetic field strength with a fixed orientation, such a method gives the correct sign of the g factor of electrons in GaAs. Furthermore, the sign of carriers in a （Ga, Mn）As magnetic semiconductor is also found to be negative.

Influence of Bipartite Qubit Coupling on Geometric Phase

The geometric phase of the bipartite Heisenberg spin-1/2 system with one spin driven by rotating magnetic field is investigated. It is found that in the one-site drive case, the intersubsystem coupling can be equivalent to a static quasi-magnetic field in the parameter space. This perspective has satisfactorily explained the irregular asymptote effect of geometric phase. We discuss the property of the two-site magnetic drive spin system and discover that a stationary state with no geometric phase shift is generated.

The Electric-Field Controllable Non-Volatile 35° Rotation of Magnetic Easy Axis in Magnetoelectric CoFeB/(001)-Cut Pb(Mg_(1/3)Nb_(2/3))O_3-25%PbTiO_3 Heterostructure

Using in situ electric-field-modulated anisotropic magnetoresistance measurement, a large reversible and non- volatile in-plane rotation of magnetic easy axis of -35° between the positive and negative electrical poling states is demonstrated in C040Fe40B20//（001）-cut Pb（Mgl/3Nb2/3）O3-25PbTiO3 （PMN-PT）. The specific magneto- electric coupling mechanism therein is experimentally verified to be related to the synchronous in-plane strain rotation induced by 109° ferroelastic domain switching in the （001）-cut PMN-PT substrate.