载脂蛋白E敲除(ApoE^(-/-))小鼠整装(whole-mount)主动脉免疫荧光组织化学染色的血管外膜淋巴管成像

目的 探索载脂蛋白E敲除(ApoE^(-/-))小鼠整装(whole-mount)主动脉免疫荧光组织化学染色法显示血管外膜淋巴管的可行性。方法 制备ApoE^(-/-)小鼠整装主动脉,进行淋巴管内皮受体1(LYVE1)、 α平滑肌肌动蛋白(α-SMA)免疫荧光组织化学染色,染色后组织经5 g/L苏丹黑B处理30 min、组织透明液透明,移至自制的样本容器中,荧光显微镜下成像。结果经5 g/L苏丹黑B处理的整装主动脉可见血管自发荧光显著降低,外膜淋巴管的特异性荧光强度显著增强,更易观察且不会对其他通道荧光产生干扰。结论 建立的ApoE^(-/-)小鼠整装主动脉免疫荧光组织化学染色显示血管外膜淋巴管的方法操作简便,特异性好。

Variation in the surface heat flux on the north and south slopes of Mount Qomolangma

The distinctive conditions present on the north and south slopes of Mount Qomolangma,along with the intricate variations in the underlying surfaces,result in notable variations in the surface energy flux patterns of the two slopes.In this paper,data from TESEBS(Topographical Enhanced Surface Energy Balance System),remote sensing data from eight cloud-free scenarios,and observational data from nine stations are utilized to examine the fluctuations in the surface heat flux on both slopes.The inclusion of MCD43A3 satellite data enhances the surface albedo,contributing to more accurate simulation outcomes.The model results are validated using observational data.The RMSEs of the net radiation,ground heat,sensible heat,and latent heat flux are 40.73,17.09,33.26,and 30.91 W m^(−2),respectively.The net radiation flux is greater on the south slope and exhibits a rapid decline from summer to autumn.Due to the influence of the monsoon,on the north slope,the maximum sensible heat flux occurs in the pre-monsoon period in summer and the maximum latent heat flux occurs during the monsoon.The south slope experiences the highest latent heat flux in summer.The dominant flux on the north slope is sensible heat,while it is latent heat on the south slope.The seasonal variations in the ground heat flux are more pronounced on the south slope than on the north slope.Except in summer,the ground heat flux on the north slope surpasses that on the south slope.

The Applicability and Productiveness of a Systematic Literature Review Methodology in Volcanology Research: Case of the Magma Pathway at the Mount Cameroon Volcano

The presented research illustrates the applicability and productiveness of the systematic literature review methodology, a non-empirical methodology in the geological sciences, particularly volcanology. The systematic literature review methodology is a replicable, rigorous, and transparent methodology for synthesizing existing literature to answer questions on a specific topic. The synthesis allows for knowledge consolidation, such as identifying knowledge gaps. In our illustration of this methodology, we focused on the expanding knowledge about the magma pathway at Mount Cameroon, one of Africa’s active volcanoes. Our synthesis of the relevant international geoscience research literature is based on the framework of knowledge about the magma pathway beneath a typical basaltic volcano. The framework has three primary components: magma supply, storage, and transport to erupting vents. Across these components is a total of twelve secondary components. The result is a previously non-existent and fragmented overall understanding of the magma pathway at Mount Cameroon. The gaps in the understanding (such as in the magma supply rates, timescales of chamber processes, and magma ascent rates) may be addressed in future research. Another key implication of the presented research lies in the proof of concept of the systematic literature review methodology as an applicable qualitative research methodology in the study of volcanoes.

Evaluation of periglacial landforms and formation of soil properties on the Mount Honaz,SW Türkiye

The main aim of this study is to explain periglacial processes on the summits of Mount Honaz(2571 m a.s.l.),define periglacial landforms,and determine the relationships between morphometric features and topographic factors.Mud circles,stony earth circles,non sorted steps,and non sorted stripes were identified on the summits of Mount Honaz.Pearson's correlation coefficient(r)and linear regression analyses were performed by taking metric measurements from 125 periglacial landforms to describe their morphometric features(length,width,height)of periglacial landforms and explain the relationships between them and topographic factors(elevation,slope).To explain the relationships between periglacial landforms and soil properties,soil samples from 11 periglacial landforms were taken and analysed.Periglacial landforms,which continue to develop on the summits of Mount Honaz today,have been evaluated with present climate data.Analysis of soil samples indicates a notable impact of parent material on the genesis of periglacial landforms.The high ratio of organic matter in mud circle and non sorted step landforms and the high lime ratio in stony earth circle landforms prove a strong relationship between the formation mechanisms of landforms and the soil properties.Furthermore,it is consistent with the findings obtained from the analysis that severe periglacial processes and washing and scavenging events are experienced more on the northern slopes.

Volcanic Risk Perception and Coping Strategies from Mounts Cameroon and Nyiragongo Eruptions, Central Africa: A Comparative Analysis

Approximately 2,000,000 people are exposed to volcanic risks in communities situated at the flanks of Mounts Cameroon (MC) and Nyiragongo (MN) volcanoes in Central Africa. This study therefore sought to investigate risk perception from four previous eruptions of MC, namely the 1959, 1982, 1999, and 2000 eruptions;and two previous eruptions of MN: 1977 and 2002. The study was initiated with co-design workshops held with major stakeholders in the cities of Buea and Goma at the flanks of MC and MN, respectively, in 2017, to develop the research objectives for the study. A non-random questionnaire survey was later conducted within 14 and 15 communities in Buea and Goma respectively, on the effects, perceived risks, and coping strategies for the chosen eruptions. Three age groups (18 - 30, 31 - 45 and >45 years) and gender (male and female) were considered. The population at the flanks of both volcanoes cited scientific and indigenous factors to be responsible for eruptions from these volcanoes. At MC and MN, ≥45% of the sampled participants (with a higher female population) perceived that the sampled eruptions posed a very high risk to the population. In terms of the effects, the age group of 18 - 30 was the least knowledgeable. In terms of direct effect on persons, over 90% of participants at MC and MN attested that they were overcome by fear/panic. On measures to cope with any likely eruption, the following order was established at the flanks of both volcanoes: sensitization of population, use of religious (prayers) and of traditional/indigenous strategies. In terms of future coping strategies, while the males at MC maintained sensitization as the favourite option, 62% of the males at MN opted for traditional/indigenous strategies. The female population at both MC and MN showed a higher preference for religious strategies like prayers.

GO WEST TO THE HOMETOWN OF MOUNT QOMOLANGMA

Lakes that resemble mirrors and jade,ancient temples,and Mount Qomolangma soaring into the clouds...If you want to experience the unique folk culture of Xizang,you can head west to Xigaze,the hometown of Mount Qomolangma.

Variations of extreme temperature in the Mount Qomolangma region in China during 1971-2020

According to observational daily temperature data from the meteorological stations during 1971-2020,the variations of the extreme temperature event in the Mount Qomolangma(also known as Mount Everest) region in China have been analyzed using statistical methods.The extreme temperature indices recommended by the World Meteorological Organization are selected to describe the extreme temperature event.The RClimDEX 1.0 software is used to calculate the extreme temperature indices.There are no tropical nights,and just three summer days at the last 50 years.The frost days are the main extreme temperature events all year round.The temperature in the north slope is more extreme than that in the south slope of the Mount Qomolangma.There is remarkable decadal variation for the extreme temperature indices except diurnal temperature range.There are the warm extremes increasing,however,the cold extremes decreasing with the decadal lapse,which is more remarkable into the 21^(th) century.The tendencies for the extreme temperature indices in the north slope are consistent with those in the south slope.There are statistically significant trends for most extreme temperature indices during the study period.It shows that the warm extremes would be more prominent in the future with the global continued warming.The abrupt changes of the extreme temperature index have occurred mainly in the 20^(th) century especially from the mid to late 1980s and 1990s.The periodic changes in the south slope do not synchronize those in the north slope for the most extreme temperature indices.It is different for most extreme temperature indices between the south and north slope,which has demonstrated that the regional or local changes are not neglectable for extreme temperature research.The results of this study are also the consistent response of extreme temperature event to the global warming.

Cavefish mount a rapid and sustained regenerative response following skeletal muscle injury

Dear Editor,Physical injury and tissue damage are prevalent throughout the animal kingdom,with the ability to regenerate quickly and efficiently providing a selective advantage.In most vertebrates,skeletal muscle possesses a remarkable ability to regenerate,making it a valuable model for investigating the cellular processes underpinning tissue regeneration.Following damage,skeletal muscle mounts a complex regenerative cascade centered around dedicated muscle stem cells,i.e.,satellite cells.These satellite cells are,in turn,regulated by both resident and infiltrating innate immune cells of myeloid lineage,which play a crucial role in activating and guiding the transition of satellite cells towards maturation(Chen et al.,2020;Tidball,2017;Tidball&Villalta,2010).While critical for muscle regeneration,the innate immune system is energetically costly,resulting in many species decreasing immune investment under nutrient-limited environments.Whether this reduced investment results in a decreased capacity to mount a regenerative response following tissue damage remains unclear.Here,we utilized an emerging evolutionary model,the Mexican tetra(Astyanax mexicanus),to investigate the consequences of shifts in immune system investment on skeletal muscle regeneration.

Petrochemical Studies of Fouimba and Goma Mounts, Central-West of Cote d’Ivoire: Implication on Petrogenesis Tectonic Setting

Petrogeochemical analysis of mafic rocks of Fouimba and Goma Mount in the Séguéla region (central-western Côte d’Ivoire) is the subject of this study. This analysis combines remote sensing, geophysics, petrography and geochemistry, in order to determine the major characteristics of the mafic formations in the said area, and above all to participate in the detailed mapping of all the Ivorian terrains. The mafic formations encountered in this region are essentially metatonalites to metadiorites, amphibolites, amphibole bearing pyroxenites and porphyry basalts. Chemical analysis indicates that these mafic formations are tonalitic to monzonitic. They are thought to have derived from mantle depleted magmas.

Identification of major sources controlling groundwater geochemistry in Mount Makabaï in the Far-North of Cameroon(the northernmost part of the Pan-African Belt)

The present work focuses on the volcanic basement rock geochemistry of Mount Makabaï(MarouaCameroon city)in relation to groundwater geochemistry.Investigations were centered on an approach involving an association of several methods such as geological cartography,hydrogeology,and geochemistry.Three rock samples,four disturbed soil samples,three undisturbed soil samples,and 20 samples of groundwater in 10 wells were collected during fieldwork and prepared for laboratory analyses.Bedrocks exhibit porphyritic,aphyric,and subaphiric textures.The phenocryst phases are mainly olivine,clinopyroxene,and plagioclase.Based on whole rock major element chemical compositions,the Makabaï samples,plotted on Na_(2)O+K_(2)O versus SiO_(2)diagram,are mugearite,hawaiite,and basalt.The ratio of(MgO+CaO)/(Na_(2)O+K_(2)O)exceeds unity and shows dominance of alkaline Earth metals(MgO:2.99-4.48%;CaO:6.19-9.80%)relatively to alkali metals(Na_(2)O:2.27-4.46%;K_(2)O:2.09-2.51%).Exchangeable base contents are high,mostly represented by Ca and Mg,whose contents vary from 14.6 to 35.28 cmol(+)kg^(-1)and from 3.28 to9.48 cmol(+)kg^(-1)respectively.The CECclayis likewise high,fluctuating between 116.80 and181.38 cmol(+)kg^(-1),values in line with the presence of 2:1 clay minerals represented in the study area by montmorillonite.In the water samples,the Ca2+and Na+contents are generally higher than K^(+)and Mg^(2+),reflecting the relative abundance of Na_(2)O and CaO oxides to K_(2)O and MgO oxides in rocks where different waters were sampled.The waters of Makabaï are acidic to neutral(6.3≤pH≤7.4)and weakly to highly mineralized(110.0≤EC≤1190.0μS/cm).Hydro-geochemical classification by using the Piper diagram revealed two water types:(1)CaMg-HCO_(3)(40%)and(2)CaMg-Cl or CaMg-SO4(60%).The average content of ions in all the analyzed samples was HCO_(3)^(-)>>NO_(3)^(-)>SO_(4)^(2-)>Cl-for anions and Ca^(2+)>>Mg^(2+)>Na^(+)>K^(+)for cations.Major mechanisms governing ionic constituents of groundwater in the study area are water-rock interactions,silicate weathering,and ion exchange.

Soil Organic Carbon Stock and Soil Quality under Four Major Agroecosystems in the Eastern Flank of Mount Bambouto (West-Cameroon)

Assessing soil organic carbon stock (SOCS) and soil quality (SQ) helps design better agricultural practices to improve environmental sustainability and productivity. The purpose of the study is to assess SOCS and soil quality SQ in the main agroecosystems (AES) of the eastern flank of Mount Bambouto (West, Cameroon). Using multiple statistics tests and principal component analysis (PCA), SOCS and Soil Quality Index (SQI) were computed for each AES. SOCS and SQI were computed based on soil chemical properties and analysis of variance. Topsoil samples (0 - 30 cm) were collected in a different AES and analyzed in the laboratory. The four AES identified and selected are cultivated land (CL), forest areas (FA), mixed areas (MA), and bush areas (BA). Further, multiple comparison tests were used to compare soils from different AES. PCA was used to select the most appropriate indicators that control SOCS and SQ. Several soil properties showed high to very high coefficient of variation within the AES. Organic matter (OM) was significantly high in FA. SOCS and SQ differ significantly (p = 0.000) between the AES. The study further indicates that the main variables controlling SQ within the eastern flank of Mount Bambouto are OM, pHw, N, C/N, and CEC. While the main soil parameters controlling SOCS are OM, OC, BD, C/N, S, and pHKCl.

Exploration of the Construction of the National Scenic Byway around Mount Tai

On the basis of traffic,scenic byways can meet tourists’tourism and leisure,catering,accommodation,social,activities,resource protection and so on.In this paper,the concept,functions,characteristics and domestic and foreign research situation of scenic byways were summarized,and the necessity and feasibility of the construction of the national scenic byway around Mount Tai were analyzed.Besides,the route selection,function orientation,construction of supporting facilities,marketing management and construction projects were discussed.Finally,it is pointed out that the construction experience of the national scenic byway around Mount Tai will be used for the construction of national scenic byways in other provinces and autonomous regions,and the national scenic byway around Mount Tai and other national scenic byways will be connected to form the national scenic byway network.It is proposed that relevant departments of the state should formulate national standards,laws and regulations for scenic byways to regulate the construction and development of scenic byways.

Research on the Exploitation of Study Tour Resources in Mount Taishan

Mount Taishan in Taian Prefecture of Shandong Province has rich study tour resources,but its development efforts are extremely disproportionate to its status as one of the five unique mountains.Through analyzing study tour in the context of its development and study tour resources in Mount Taishan,and based on the in-depth analysis of the existing problems,the proposals for the development of resources were put forward:highlight the main line and enrich the study activities to create study bases around Mount Taishan;improve the study services through the research and development of special products;expand the publicity to promote the educational products and research products.

Mount Taishan:The Supreme of the Five Sacred Mountains

MOUNT Taishan is one of the spiritual symbols of Chinese civilization,and an imperial,ritual place where emperors once paid homage to heaven and earth.Located in the central part of east China’s Shandong Province,Mount Taishan stretches more than 200 kilometers from east to west and 50 kilometers from north to south,with a total area of about 426 square kilometers and a maximum altitude of 1,545 meters.In ancient times.

The Echoes of Ecological Secrets of Mount Qomolangma from Ancient Times

The majestic Mount Qomolangma is the Earth’s highest peak at 8,848 meters above sea level.Located in the Himalaya,it straddles the China-Nepal border.This mighty mountain holds many secrets about the geological history and environmental changes of the Qinghai-Tibetan Plateau.In April 2022,Chinese scientists launched a largescale comprehensive scientific investigation in the Mount Qomolangma region,called the“Earth Summit Mission”.Herein,I am very pleased to recount what occurred to our team’s paleontological field investigation during this scientific endeavor and the one before it.

Ascend Mount Tai to View the World

From September 3 to 6,“Ascend Mount Tai to View the World”The 37th Mount Tai International Mountain Climbing Festival,jointly sponsored by the Network of International Culturalink Entities of the Ministry of Culture and Tourism,Shandong Provincial Department of Culture and Tourism and the People's Government of Tai'an City,was held in Tai'an City,Shandong Province.

Ascend Mount Tai to View the World The 37th Mount Tai International Mountain Climbing Festival

From September 3 to 6,"Ascend Mount Tai to View the World"The 37th Mount Tai International Mountain Climbing Festival,jointly sponsored by the Network of International Culturalink Entities of the Ministry of Culture and Tourism,Shandong Provincial Department of Culture and Tourism and the People's Government of Tai'an City,was held in Tai'an City,Shandong Province.

基于新能源-负荷相似性的源荷储协调调峰优化调度

合理利用可调节负荷的响应特性来实现源荷储的协调调度,可有效缓解新能源、负荷的不确定性所带来的调峰压力。基于新能源-负荷(NER-L)相似性,建立可调节负荷响应目标。基于相关系数,建立能准确刻画负荷对新能源出力跟踪匹配程度的NER-L相似性指标,并将指标引入所建源荷储协调调峰的双阶段优化调度模型。第一阶段模型以NER-L相关系数最大为目标,确定可调节负荷在各时段的响应功率并获得最优电网负荷;第二阶段模型以弃风弃光量最小、调峰运行成本最低为目标,优化火电机组及储能出力。以IEEE 30节点系统为例,对NER-L相似性、净负荷峰谷差、系统调峰运行经济性及新能源弃电功率进行计算分析,结果验证了所提模型的有效性。

大涵道比涡扇发动机安装节动力学设计及性能评估分析进展

综述了大涵道比涡扇发动机安装节动力学设计及评估问题。首先从减振设计需求出发,论述了发动机安装节开展动力学设计的重大意义,并对安装节的主要结构形式及特点进行了详细的阐述;进一步从军民用标准规范和工程实践经验出发,归纳了安装系统动力学设计技术要求;而后从动力学设计、性能评估、系统验证等方面回顾了涡扇发动机安装节的国内外研究现状,指出国内外差距主要体现在设计要求、设计理念和应用实践经验等方面。在此基础上,展望了大涵道比涡扇发动机安装节动力学设计及性能评估技术的发展趋势和热点。

基于频率响应与图像特征提取的动车组变压器绕组状态诊断方法研究

动车组变压器是保障高速铁路稳定运行的核心设备,频率响应法是目前检测变压器绕组状态的有效方法。为提升车载变压器绕组状态诊断的准确性,结合暂态信号与频率响应法提出基于频率响应与图像特征提取的动车组变压器绕组状态诊断方法。搭建试验车载变压器绕组故障模拟平台,获取不同故障类型和故障位置的频响曲线,利用类Gram矩阵结合幅频和相频曲线信息,再利用密度分层法转换为伪彩色图,提取对应的灰度共生矩阵和灰度差分矩阵特征值,根据鹈鹕优化支持向量机方法对绕组故障进行诊断。试验结果表明:车载变压器绕组故障发生时,伪彩色图能够反映出故障信息,有利于图像分析和特征提取,采用基于频率响应与图像特征提取的动车组变压器绕组状态诊断方法能够识别车载变压器绕组的典型故障类型和位置。