Traditional Chinese medicine (TCM) plays a very important role in Chinese people ’ s health-keeping, enjoying an position of the same significance with Western medicine and drugs. Entering into the 21 century, and du...Traditional Chinese medicine (TCM) plays a very important role in Chinese people ’ s health-keeping, enjoying an position of the same significance with Western medicine and drugs. Entering into the 21 century, and due to the swift and drastic development in economy and elevation in living quality, the public have come to pay much more展开更多
Objective] This study was conducted to evaluate the product quality and safety of Peristrophe roxburghiana_ col ected from different places in Hechi City, northwest of Gunagxi, so as to provide basic data for further ...Objective] This study was conducted to evaluate the product quality and safety of Peristrophe roxburghiana_ col ected from different places in Hechi City, northwest of Gunagxi, so as to provide basic data for further development and uti-lization of the characteristic plant resource P. roxburghiana. [Method] Contents of 9 kinds of heavy metals including Cd, Mn, Pb, Zn and Cu in the herb were deter-mined by the method of wet digestion-flame atomic absorption spectrophotometry and atomic fluorescence spectrometry, respectively. [Results] Heavy metal contents of Cd, Mn, Pb, Fe, Cu, Zn, As, Hg and Se were 1.62-17.25, 8.93-142.53, 4.37-18.43, 103.7-242.81, 2.55-5.35, 85.40-146.30, 0.07-0.54, 0.00-0.08 and 0.00-0.47 mg/kg, respectively. According to the national food safety standards and Green Trade Standards of lmporting & Exporting Medicinal plants & Preparations, the heavy metal contents of the P. roxburghiana_samples col ected from different coun-ties in Hechi City exceeded standards or at the critical values. Among which, Cd, Pb and Zn contents of the samples are seriously higher than the standards. [Con-clusion] Therefore, the impact of soil heavy metal pol ution on the safety of edible plants in the northwest of Guangxi should be highly concerned.展开更多
Chinese herbal medicines(CHMs)are playing important roles in the treatment of diseases and human health care throughout the world.However,the extrinsic harmful residues have been threatening the therapies by destroy...Chinese herbal medicines(CHMs)are playing important roles in the treatment of diseases and human health care throughout the world.However,the extrinsic harmful residues have been threatening the therapies by destroying CHMs qualtiy which hinders the international trades of CHMs.This review summarized the extrinsic harmful residues contaminating CHMs in types,detection methods,national and international regulations,and made safety evaluations according to their contaminated levels,aiming to establish understanding among nations or organizations and provide references for the formulation or amendment of relative regulations.展开更多
OBJECTIVE:To evaluate the clinical efficacy and safety of external application of Chinese herbal medicine(exCHM)for psoriasis vulgaris(PV).METHODS:Different search portals,including the China National Knowledge Infras...OBJECTIVE:To evaluate the clinical efficacy and safety of external application of Chinese herbal medicine(exCHM)for psoriasis vulgaris(PV).METHODS:Different search portals,including the China National Knowledge Infrastructure Database,China Science and Technology Journal Database,Wanfang,Sino Med,clinicaltrials,Pub Med,Cochrane Library,and Cochrane Central Register of Controlled Trials,were searched for randomized controlled trials(RCTs)that compared the ex-CHM intervention with other treatment protocols for PV,with available data as of November 25,2020.The Review Manager 5.3 software was used for analysis.RESULTS:Nineteen RCTs involving 1988 participants were included,of which twelve RCTs qualified for the Meta-analysis.The results showed that the addition of CHM bath to narrow-band ultraviolet B(NB-UVB)had a higher response rate[RR=1.29;95%CI(1.19,1.40);P<0.00001];lower psoriasis area severity index(PASI)[MD=-3.15;95%CI(-4.79,-1.52);P=0.0002],adverse reactions rate[RR=0.32;95%CI(0.15,0.66);P=0.002],and recurrence rate[RR=0.48;95%CI(0.30,0.79);P=0.004]than NB-UVB alone.The addition of CHM fumigation to NB-UVB also showed a higher response rate[RR=1.29;95%CI(1.11,1.49);P=0.0007]and lower adverse reactions rate[RR=0.44;95%CI(0.24,0.79);P=0.006].In addition,CHM bath could reduce the adverse reactions induced by 308 nm excimer laser and improve patients’quality of life better than phototherapy.CHM fumigation could improve the efficacy of calcipotriol ointment and reduce the adverse reactions.CHM fumigation combined with external washing plus acitretin showed better results than using acitretin alone.No statistical difference was observed between CHM external washing and calcipotriol ointment or CHM ointment and retinoic acids.CONCLUSIONS:Current evidence showed that CHM bath and fumigation appeared to be efficient and safe for PV treatment.However,no definite conclusion could be drawn due to the low quality of included studies and thus more well-designed studies are needed for further assessment.展开更多
As a series of and continuous publication,the papers published on Chinese Traditional and Herbal Drugs in 2010 were selectively and briefly highlighted to reflect the new progress on modern research of Chinese herbal ...As a series of and continuous publication,the papers published on Chinese Traditional and Herbal Drugs in 2010 were selectively and briefly highlighted to reflect the new progress on modern research of Chinese herbal medicines.Within 617 articles,chemical constituents(127),pharmaceutics and technology(149),pharmacological studies and clinical observation,and medicinal materials are still major categories.Some comments have also been personally provided.展开更多
文摘Traditional Chinese medicine (TCM) plays a very important role in Chinese people ’ s health-keeping, enjoying an position of the same significance with Western medicine and drugs. Entering into the 21 century, and due to the swift and drastic development in economy and elevation in living quality, the public have come to pay much more
基金Supported by Fund for Key Laboratories in Guangxi Universities-Featured Resource Research and Development Laboratory of Northwest of Guangxi(GJKY 2010[6])Fund for Platform Built by University and Local Government or University and EnterpriseLocal Resource Protection and Utilization Engineering Center of Northwest of Guangxi(GJKY 2010[9])~~
文摘Objective] This study was conducted to evaluate the product quality and safety of Peristrophe roxburghiana_ col ected from different places in Hechi City, northwest of Gunagxi, so as to provide basic data for further development and uti-lization of the characteristic plant resource P. roxburghiana. [Method] Contents of 9 kinds of heavy metals including Cd, Mn, Pb, Zn and Cu in the herb were deter-mined by the method of wet digestion-flame atomic absorption spectrophotometry and atomic fluorescence spectrometry, respectively. [Results] Heavy metal contents of Cd, Mn, Pb, Fe, Cu, Zn, As, Hg and Se were 1.62-17.25, 8.93-142.53, 4.37-18.43, 103.7-242.81, 2.55-5.35, 85.40-146.30, 0.07-0.54, 0.00-0.08 and 0.00-0.47 mg/kg, respectively. According to the national food safety standards and Green Trade Standards of lmporting &amp; Exporting Medicinal plants &amp; Preparations, the heavy metal contents of the P. roxburghiana_samples col ected from different coun-ties in Hechi City exceeded standards or at the critical values. Among which, Cd, Pb and Zn contents of the samples are seriously higher than the standards. [Con-clusion] Therefore, the impact of soil heavy metal pol ution on the safety of edible plants in the northwest of Guangxi should be highly concerned.
基金supported by CAMS Innovation Fund for Medical Sciences (No. 2016-I2M-1-012, 2017-I2M-1-013)National Natural Science Foundation of China (No. 81573595, 81703699)National Project for Standardization of Chinese Materia Medica (No. ZYBZH-Y-JIN-34)
文摘Chinese herbal medicines(CHMs)are playing important roles in the treatment of diseases and human health care throughout the world.However,the extrinsic harmful residues have been threatening the therapies by destroying CHMs qualtiy which hinders the international trades of CHMs.This review summarized the extrinsic harmful residues contaminating CHMs in types,detection methods,national and international regulations,and made safety evaluations according to their contaminated levels,aiming to establish understanding among nations or organizations and provide references for the formulation or amendment of relative regulations.
基金Supported by the National Natural Science Foundation of China:to Study the Immunoanti-inflammatory Mechanism of Cooling Blood Detoxification Methods for Psoriasis Treatment from Influence of S1P/S1PRs to Th17/KC Inflammatory Axis(No.81874393)
文摘OBJECTIVE:To evaluate the clinical efficacy and safety of external application of Chinese herbal medicine(exCHM)for psoriasis vulgaris(PV).METHODS:Different search portals,including the China National Knowledge Infrastructure Database,China Science and Technology Journal Database,Wanfang,Sino Med,clinicaltrials,Pub Med,Cochrane Library,and Cochrane Central Register of Controlled Trials,were searched for randomized controlled trials(RCTs)that compared the ex-CHM intervention with other treatment protocols for PV,with available data as of November 25,2020.The Review Manager 5.3 software was used for analysis.RESULTS:Nineteen RCTs involving 1988 participants were included,of which twelve RCTs qualified for the Meta-analysis.The results showed that the addition of CHM bath to narrow-band ultraviolet B(NB-UVB)had a higher response rate[RR=1.29;95%CI(1.19,1.40);P<0.00001];lower psoriasis area severity index(PASI)[MD=-3.15;95%CI(-4.79,-1.52);P=0.0002],adverse reactions rate[RR=0.32;95%CI(0.15,0.66);P=0.002],and recurrence rate[RR=0.48;95%CI(0.30,0.79);P=0.004]than NB-UVB alone.The addition of CHM fumigation to NB-UVB also showed a higher response rate[RR=1.29;95%CI(1.11,1.49);P=0.0007]and lower adverse reactions rate[RR=0.44;95%CI(0.24,0.79);P=0.006].In addition,CHM bath could reduce the adverse reactions induced by 308 nm excimer laser and improve patients’quality of life better than phototherapy.CHM fumigation could improve the efficacy of calcipotriol ointment and reduce the adverse reactions.CHM fumigation combined with external washing plus acitretin showed better results than using acitretin alone.No statistical difference was observed between CHM external washing and calcipotriol ointment or CHM ointment and retinoic acids.CONCLUSIONS:Current evidence showed that CHM bath and fumigation appeared to be efficient and safe for PV treatment.However,no definite conclusion could be drawn due to the low quality of included studies and thus more well-designed studies are needed for further assessment.
文摘As a series of and continuous publication,the papers published on Chinese Traditional and Herbal Drugs in 2010 were selectively and briefly highlighted to reflect the new progress on modern research of Chinese herbal medicines.Within 617 articles,chemical constituents(127),pharmaceutics and technology(149),pharmacological studies and clinical observation,and medicinal materials are still major categories.Some comments have also been personally provided.