Nitric oxide(NO)participates in various pathways and revealing its dynamics is critical for resolving its pathophysiology.While there are methods available for detecting biological NO,few are capable of tracking NO dy...Nitric oxide(NO)participates in various pathways and revealing its dynamics is critical for resolving its pathophysiology.While there are methods available for detecting biological NO,few are capable of tracking NO dynamics.Herein,inspired by the cellular machinery of reversible thiol modification by NO,we have successfully designed a family of cysteine analogues tagged with fluorophores for visualizing cellular NO dynamics.展开更多
Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）,Ag~＋ phosphors were synthesized by solid-state reaction technique. The crystalline phase and luminescence performances of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）,Ag~＋ were observe...Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）,Ag~＋ phosphors were synthesized by solid-state reaction technique. The crystalline phase and luminescence performances of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）,Ag~＋ were observed by X-ray powder diffractometer（XRD）, transmission electron microscope（TEM）, photoluminescence spectrometer and brightness meter, respectively. The addition of Ag~＋ can diminish in the crystal particle sizes of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）. Because Ag＋ can reduce the concentration of the undesirable defects in the phosphor, luminescence intensity of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）,Ag~＋ is 2.3 times as high as that of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）at the same preparation condition. The effect of Ag＋ on the persistent afterglow properties is to deepen the energy storage traps and enhance the energy transfer efficiency from Ca_（0.9）Mg_（0.1）TiO_3 to Pr^（3＋）. The persistent afterglow properties of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）,Ag~＋ are better than those of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋） at the same preparation condition. In conclusion,Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）,Ag~＋ phosphor with molar ratio of Ag~＋to Pr^（3＋） 3：1 obtained at 900 ℃ for 4 h exhibits the optimal photoluminescence performances.展开更多
基金supported by the National Natural Science Foundations of China(nos.22077112,21778048,81673489,31871414,and 81125023)Natural Science Foundation of Zhejiang Province,China(no.LR18H300001)National Science and Technology Major Project“Key New Drug Creation and Manufacturing Program”(nos.2018ZX09711002-010-004,2018ZX09711002-007-002,2019ZX09201001-003-009,2019ZX09201001-003-010,and 2019ZX09201001-004-010),K.C.Wong Education Foundation,and Singapore University of Technology and Design(SUTD)[SUTD-ZJU IDEA grant nos.T1SRCI17126 and SUTD-ZJU(VP)201905].
文摘Nitric oxide(NO)participates in various pathways and revealing its dynamics is critical for resolving its pathophysiology.While there are methods available for detecting biological NO,few are capable of tracking NO dynamics.Herein,inspired by the cellular machinery of reversible thiol modification by NO,we have successfully designed a family of cysteine analogues tagged with fluorophores for visualizing cellular NO dynamics.
基金Project supported by the Education Department of Yunnan,China(Grant No.2015Y103)
文摘Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）,Ag~＋ phosphors were synthesized by solid-state reaction technique. The crystalline phase and luminescence performances of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）,Ag~＋ were observed by X-ray powder diffractometer（XRD）, transmission electron microscope（TEM）, photoluminescence spectrometer and brightness meter, respectively. The addition of Ag~＋ can diminish in the crystal particle sizes of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）. Because Ag＋ can reduce the concentration of the undesirable defects in the phosphor, luminescence intensity of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）,Ag~＋ is 2.3 times as high as that of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）at the same preparation condition. The effect of Ag＋ on the persistent afterglow properties is to deepen the energy storage traps and enhance the energy transfer efficiency from Ca_（0.9）Mg_（0.1）TiO_3 to Pr^（3＋）. The persistent afterglow properties of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）,Ag~＋ are better than those of Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋） at the same preparation condition. In conclusion,Ca_（0.9）Mg_（0.1）TiO_3：Pr^（3＋）,Ag~＋ phosphor with molar ratio of Ag~＋to Pr^（3＋） 3：1 obtained at 900 ℃ for 4 h exhibits the optimal photoluminescence performances.
