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Urban Growth Modelling Using Determinism and Stochasticity in a Touristic Village in Western Greece
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作者 Dimitrios P. Triantakonstantis 《Open Journal of Civil Engineering》 2012年第1期42-48,共7页
Urban development has acquired an important magnitude in touristic places in Greece. Many villages, especially in seaside areas have adapted to touristic requirements by the necessary infrastructures and activities. P... Urban development has acquired an important magnitude in touristic places in Greece. Many villages, especially in seaside areas have adapted to touristic requirements by the necessary infrastructures and activities. Pogonia, located in Vonitsa Etoloakarnanias, is a village which has welcomed the opportunity of touristic development. As a result, the house settlements increased 57.5% during the last 8 years. Urban growth modelling using Artificial Neural Networks (ANNs) was applied in order to simulate the urban development in Pogonia village using two methods: determinism and stochasticity. The variables used for deterministic simulation were: distances to roads, urban areas and coastline, slope and elevation. It was found that urban development can be better described using the network of distances between all urban settlements (stochastic approach) rather than using determinism. This can be explained by the importance of the neighbourhood relationships and the interaction between urban settlements, occurred within the interconnected network of the self-organized urban system. 展开更多
关键词 Urban Growth MODELLING determinism Stochasticiy Pogonia Artificial Neural Network CHAOS Theory
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Laboratory Growth of <i>Anopheles gambiae</i>(Diptera: Culicidae) and Morphological Determinism of Moulting
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作者 Henri Gabriel Tsila Patrick Akono Ntonga +2 位作者 Alvine Larissa Meyabeme Elono Timoleon Tchuinkam Mpoame Mbida 《Advances in Entomology》 2021年第4期176-185,共10页
Growth in arthropods in general and in insects in particular, is supposed to be discontinuous and occurs during moulting. In Culicidae in general and <i> <i><span style="font-family:Verdana;"&... Growth in arthropods in general and in insects in particular, is supposed to be discontinuous and occurs during moulting. In Culicidae in general and <i> <i><span style="font-family:Verdana;">Anopheles</span></i></i><span style="font-family:Verdana;"> in particular, the number of moults is five with the fourth which gives the pupae. It is known that moulting in insects is a genetic and physio</span><span><span style="font-family:Verdana;">logical phenomenon. Most physiological reactions are triggered by chemical or physical stimuli. The pressure exerted by the growth of the larval body on the exocuticle is one of the triggers of moulting. The objective of this work was therefore to determine the exact timing of the first three moults that determine the growth of <i></i></span><i><i><span style="font-family:Verdana;">An. gambiae</span></i></i></span><span style="font-family:Verdana;"> larvae from egg hatch to pupation to highlight the role of increased larval size in the stimulation of moulting. We therefore, undertook to rear larvae of this anopheline species</span><i> </i><span style="font-family:Verdana;">in the laboratory under conditions close to their natural environment from hatching to pupation. The length and width of the head, thorax and abdomen were recorded daily. Data analysis showed that the size of the head and thorax remained constant for the first three days (D0 to D2) of development and ab</span><span style="font-family:Verdana;">domen’s length for the first two days and then increased daily until day seven (D7) when it stopped. These observations led us to say that the M1 moult occurs at end of the third day of development and the M3 moult at end of the eighth day;the M2 moult could not be determined. All these observations led </span><span><span style="font-family:Verdana;">to the conclusion that the larval growth of <i> </i></span><i><i><span style="font-family:Verdana;">An. gambiae</span></i></i></span><span style="font-family:Verdana;"> has a continuous</span><span style="font-family:Verdana;"> regimen and the growth of the head and thorax of the larva plays a crucial role in the onset of moulting.</span> 展开更多
关键词 Anopheles gambiae Larva GROWTH determinism Body Sizes MOULTING
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Determinism, Free Will, and Moral Responsibility
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作者 Paul Appiah-Sekyere 《Journal of Philosophy Study》 2013年第11期1032-1041,共10页
Human beings live amidst several bonds. These bonds often place both internal and external limitations that apparently create the view that a human being has no free will but is determined. This paper explores the con... Human beings live amidst several bonds. These bonds often place both internal and external limitations that apparently create the view that a human being has no free will but is determined. This paper explores the controversial issue whether a human being possesses free will to make free choices or is determined. It is the stance of this study that if one does not have free will then one cannot be morally responsible for one's actions and consequently praise and blame would then have no value. The paper, therefore, is of the view that notwithstanding the many bonds within which they live, humans, with their special dignity, have free will that operate within the respective constraints set by the bonds of human life. Furthermore, since morality involves good and bad, the paper asserts that for an act to be designated as morally good or bad, it implies that the agent was free to perform the said act or do otherwise to merit praise or blame respectively. Thus, for human freedom to be significant, it must be responsible. 展开更多
关键词 determinism Free will Moral Responsibility
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Quantum Inverse Measurement Theory Contributing to the Birth of Interpretation System of Quantum Mechanics of Local-Realism and Determinism
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作者 Runsheng Tu 《Journal of Modern Physics》 2017年第8期1398-1469,共72页
The existing interpretation of quantum mechanics is contrary to common sense. The existing quantum mechanical interpretation schemes are puzzling. The confusing theory is unconvincing, and needs to be amended and comp... The existing interpretation of quantum mechanics is contrary to common sense. The existing quantum mechanical interpretation schemes are puzzling. The confusing theory is unconvincing, and needs to be amended and completed. The successful interpretation program of quantum mechanics of local-realism and determinism is undoubtedly the most attractive. Preparing the interpretation program deserves to be chosen as a research goal. It is a very good premise to believe that an object particle consists of light-knot of monochromatic waves. According to this premise, the erroneous recognition about “superposition principle, wave-particle duality and uncertainty principle” can be corrected. Under this premise, above research goal is achieved by establishing, applying quantum mechanics inverse measurement theory, adhering to the principle that there must be a complete empirical chain in the derivation process of experimental conclusion, and using the side effect caused by accompanying-light to explain the diffraction experiment of object particles. Electron secondarily diffraction and other experiments directly prove that there is the measurement (observation) which may not destroy quantum coherence. The diffraction experiments of all kinds of particles show that the Keeping and playing of the coherence of moving particles in the vacuum have nothing to do with their previous experience. These are the existing experiments, to be found, that support the theory of quantum inverse measurements. The verification experiment of quantum inverse measurement is designed. The absolute superiorities of quantum inverse measurement and the new view of measurement of quantum mechanics are listed. These superiorities are that: it has the characteristics of local-realism and determinism;it is not contrary to common sense and there is no confusing place;it can predict several phenomena that cannot be predicted by other theories. A solid theoretical foundation has been laid for “correctly understanding the microscopic world” and establishment of local realism quantum mechanics. 展开更多
关键词 QUANTUM INVERSE MEASUREMENT LOCAL REALISM determinism QUANTUM Entanglement Tu’s MEASUREMENT View of QUANTUM Mechanics Light-Knot Electronic Structure Model
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Relativity of a Free Will Concept Depending on Both Conscious Indeterminism and Unconscious Determinism
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作者 Franz Klaus Jansen 《Journal of Philosophy Study》 2011年第2期103-117,共15页
Free will is difficult to classify with respect to determinism or indeterminism, and its phenomenology in consciousness often shows both aspects. Initially, it is felt as unlimited and indeterminate will power, with t... Free will is difficult to classify with respect to determinism or indeterminism, and its phenomenology in consciousness often shows both aspects. Initially, it is felt as unlimited and indeterminate will power, with the potentiality of multiple choices. Thereafter, reductive deliberation is led by determinism to the final decision, which realises only one of the potential choices. The reductive deliberation phase tries to find out the best alternative and simultaneously satisfying vague motivations, contextual conditions and personal preferences. The essential sense of free will is the introduction of personal preferences, which allows a higher diversity of reactions to vague motivations. With an oversimplified model of determinism as a chain of events, incompatibilists define "free" as "undetermined" so that determinism becomes incompatible with any free choice between alternatives. In consciousness, free will requires a more complex model of network determinism as well as the consideration of unconsciousness as a causal factor. When "free" defined as "undetermined" is applied to the context of consciousness, it should be reinterpreted as "unconscious of being determined" or not aware of underlying determinism. Lacking information on determinism generates a feeling of "free" in consciousness and, therefore, gives the impression of indeterminism. Lacking information may be induced by an uncertain future without determined events--an unconscious past with biological reactions suddenly emerging from the unconsciousness or an unknown present unable to distinguish determinism of complex events. Therefore, at the level of human consciousness, the experience of free will is associated with apparent indeterminism although it is based on unconscious determinism. The concepts of compatibilism and incompatibilism are only two different aspects of the same phenomenon and correspond to consciousness and unconsciousness. Nevertheless, they can be considered together with a free will concept based on relativity depending on two different reference frames--the first person's experience frame or the Laplace's demon frame with knowledge on every molecule of the universe. Only relativity of the free will concept avoids the contradiction between "free" and "unfree" for the same phenomenon and could be a compromise for considering compatibilism and incompatibilism equally. 展开更多
关键词 free will determinism INdeterminism consciousness UNCONSCIOUSNESS RELATIVITY reference frames MOTIVATIONS personal preferences
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Attempting Discussion of Mythological Concepts' Determinism
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作者 YE Shu-xian 《Journal of Literature and Art Studies》 2015年第12期1158-1167,共10页
Current sciences fail in understanding the future trends of human beings' behaviors and cultures. From the hunting tribes to the agricultural society, the civilized country, and then to the industrial society, none o... Current sciences fail in understanding the future trends of human beings' behaviors and cultures. From the hunting tribes to the agricultural society, the civilized country, and then to the industrial society, none of these developments is the results of human beings' reasonable proposal. The human beings are "developed", i.e. pushed forward by certain invisible forces. As being cultural, they are dominated by their cultural concepts. To explore the source of every civilization's concepts, the formation history of its mythological concepts during the pre-historic period or at the beginning of its civilization shall be studied first. By interpreting the first literature works at the beginning of western civilization, the temporary mythologists reveal the rule that mythological concepts dominate the ritual behaviors and narrative expressions. This paper interprets the historical narratives in Records of the Grand Historian." Annals of the First Emperor of Qin, to reproduce the concepts that dominate China's national rulers, present the theory of Mythological Concepts' Determinism, and correspond to the counter-force of ideology put forward by Friedrich Engels in his later years and the religious concepts' determinism by Max Weber, so as to illustrate the mythological concepts' function as the prototype code of ideology, and refer to a common and effective directory approach of social science studies. 展开更多
关键词 human beings being developed MYTHOLOGY mythological concepts determinism historical causaltheory
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DETERMINE评分与急性心肌梗死PCI术预后关系的分析
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作者 李加乐 刘泽岩 程景林 《中文科技期刊数据库(引文版)医药卫生》 2024年第5期0051-0054,共4页
探讨DETERMINE评分(病理性Q波导联数*2+碎裂QRS波导联数+T波倒置导联数)与急性心肌梗死患者经皮冠状动脉介入(PCI)术后预后的关系。方法 选择2021.1-2022.12在我院住院接受PCI治疗的急性心肌梗死患者206例,根据预后情况分为预后良好组(... 探讨DETERMINE评分(病理性Q波导联数*2+碎裂QRS波导联数+T波倒置导联数)与急性心肌梗死患者经皮冠状动脉介入(PCI)术后预后的关系。方法 选择2021.1-2022.12在我院住院接受PCI治疗的急性心肌梗死患者206例,根据预后情况分为预后良好组(165例)和预后不良组(41例)。比较两组患者的临床资料及DETERMINE评分,采用多因素Logistic回归法分析影响急性心肌梗死PCI术后预后的相关因素;创建受试者工作特征曲线(ROC),分析DETERMINE评分对急性心肌梗死PCI术后预后的预测价值。分析急性心肌梗死PCI术预后不良的影响因素。结果 与预后良好组比较,预后不良组糖尿病史、心律失常史比例及DETERMINE评分、年龄、体重指数、左室射血分数、糖化血红蛋白、低密度脂蛋白胆固醇、总胆固醇水平均显著升高,差异具有统计学意义;二元Logistic回归分析显示DETERMINE评分、心律失常史、体重指数、糖化血红蛋白、低密度脂蛋白胆固醇是冠心病患者PCI手术预后不良的独立危险因素(OR=1.443~15.658,P<0.05)。结论 DETERMINE评分与冠心病PCI术预后相关,需引起临床关注。 展开更多
关键词 determinE评分 急性心肌梗死 PCI术后 预后
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On Reflection of Environmental Determinism in The Call of the Wild
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作者 罗垚 《海外英语》 2016年第7期169-170,共2页
This essay intends to find out the key functions of environment in different periods of Buck's life by further analysis of the author and the novel itself.Besides,under the direction of environmental determinism,t... This essay intends to find out the key functions of environment in different periods of Buck's life by further analysis of the author and the novel itself.Besides,under the direction of environmental determinism,this essay analyzes the reasons that Buck changes into a wild wolf from a civilized dog. 展开更多
关键词 BUCK ENVIRONMENTAL determinism ADAPTION
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A Comparative Study of Sister Carrie and Xiangzi Based on Environmental Determinism
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作者 HUANG Linling YAN Chunmei 《Sino-US English Teaching》 2021年第9期261-265,共5页
Dreiser’s Sister Carrie and Lao She’s Camel Xiangzi are two classic novels.Both of them demonstrate the decisive influence of environmental factors on the characters’destiny.This paper tries to explore their tragic... Dreiser’s Sister Carrie and Lao She’s Camel Xiangzi are two classic novels.Both of them demonstrate the decisive influence of environmental factors on the characters’destiny.This paper tries to explore their tragic fates comparatively based on environmental determinism.Actually,the two protagonists of two novels were both dream chasers in social changes at first,and then they transformed into strugglers under the oppression of patriarchy and biological power,and eventually they became victims of the social values under the fateful role of the environment.Obviously,the fights between the two protagonists and the environment have certain enlightening effects on current human life and the process of urbanization. 展开更多
关键词 environmental determinism Sister Carrie Xiangzi comparative study
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Determinants of Modern Contraceptive Uptake among the Youth in Akuse Township in the Lower Manya Krobo Municipality, Ghana
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作者 Raymond Mawusi Amenya Stephen Manortey +2 位作者 Millicent Ofori Boateng Sandra Kushitor Edward Sutherland 《Health》 2024年第1期72-86,共15页
Background: Access to safe and effective contraception is crucial for sexual and reproductive health to be at its best. This allows improved pregnancy results and the avoidance of unintended births. Teenagers’ views ... Background: Access to safe and effective contraception is crucial for sexual and reproductive health to be at its best. This allows improved pregnancy results and the avoidance of unintended births. Teenagers’ views on using contraceptives are influenced by the information available at their disposal. The study assessed the influential factors affecting the utilization of modern contraceptives among the youth in Akuse in the Eastern Region of Ghana. Methods: The data for the study were gathered from 378 consented youth aged 15 - 24 years using a quantitative cross-sectional study design and a well-structured questionnaire. Person’s Chi-Square test was adopted to measure the association between the outcome variable and selected independent variables. Logistic regression models were utilized to measure the odds of the factors influencing modern contraceptive use among the respondents. Results: The results of the study suggested a high knowledge level of contraceptives;however, the prevalence of utilization was low. The level of education and age were factors found to influence the uptake of contraceptives. A bivariate analysis to examine the association between selected socio-demographic variables revealed that educational level (p = 0.044), religious affiliation (p = 0.002), and ethnicity (p = 0.016) were statistically associated with modern contraceptive use among the respondents. All other tested demographic variables including the age groups, gender, marital status, and residential status proved otherwise at the observed p-values greater than the 0.05 threshold. Respondents who indicated staying with partners were 6.79 times more likely to use contraceptives compared to their counterparts staying with a parent, after controlling for all other covariates. Conclusions: Based on the findings of this study, it was concluded that high contraceptive knowledge influences the choice of contraceptive preferred by the youth, and contraceptive use is also influenced by the advancement in age and educational level of the youth. It is however recommended that parents, guidance, and teachers be entreated to offer relevant and timely sexual information or education as these will most likely improve the uptake of modern contraceptives among the targeted population. 展开更多
关键词 determinants Modern Contraceptive YOUTH Akuse Ghana
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Sex Determination in Homo sapiens as a Multi-Step Process: Potential for Development of Variants and Sex Differences in Disease Risk
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作者 David A. Hart 《Journal of Biomedical Science and Engineering》 2024年第1期13-34,共22页
Reproduction via cis-binary mechanisms appears to have evolved fairly early in the evolution of complex organisms, and a system committed to prior to evolution of humans. While the evolution of a chromosomal-specific ... Reproduction via cis-binary mechanisms appears to have evolved fairly early in the evolution of complex organisms, and a system committed to prior to evolution of humans. While the evolution of a chromosomal-specific approach has been a successful strategy for survival of a large variety of species including humans, the fidelity of sex determination leading to 100% cis-binary outcomes is not achieved in many species, with evidence for homosexual or bisexual behaviour evident in more than 1500 species. Thus, such outcomes indicates that sex determination is a multi-step process and not a single event, and as such, could lead to the appearance of variants during the process which developed much earlier than humans. Variants could arise either due to intrinsic variation in the steps of determination, or also be influenced by environmental factors of a biological or psychological nature. In contrast to homosexual variants which do not require interventions such as hormone therapy or surgery, expression of gender dysphoria, is more based in psychology, but also has biological underpinnings and can be influenced by such hormonal interventions and surgery. While the numbers of those with gender dysphoria is small (~0.6% - 1.0% of population), the attention given to this issue raises the possibility of biological and psychological environmental factors impacting the emergence of some of those expressing gender dysphoria. Furthermore, transitioning from male-to-female or female-to-male can have consequences regarding disease risks latter in life, including the appearance of autoimmune diseases. This review will attempt to review some of the evidence regarding sex determination, discuss why the system has potentially not been improved upon during evolution, how a potential role for sex chromosome function on neurodevelopment may be central to variation in humans, and how commitment to the current strategy is likely integrated into other sex-related events such as puberty, pregnancy, and menopause to ensure species survival. It will also discuss how variants in sex determination could contribute to sex differences in disease risk and how epigenetic modifications could play a role in such risk. . 展开更多
关键词 Sex determination Variant Development Fidelity of Sex determination Biological Sex determination Species Variation
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Relationship Between Language and Thought:Linguistic Determinism,Independence,or Interaction?
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作者 Jing Li 《Journal of Contemporary Educational Research》 2022年第5期32-37,共6页
The relationship between language and thought has long been a topic of great interest in the field of linguistics,especially in psycholinguistics.Herder,Humboldt,Trendelenburg Sapir,Whorf,Gui Shichun,Lian Shuneng,and ... The relationship between language and thought has long been a topic of great interest in the field of linguistics,especially in psycholinguistics.Herder,Humboldt,Trendelenburg Sapir,Whorf,Gui Shichun,Lian Shuneng,and Bao Human are some of the well-known scholars who have conducted research on the relationship between language and thought.With regard to the relationship between language and thought,there are three main viewpoints.The first group of scholars,represented by Sapir and Whorf,supports linguistic determinism.Some scholars believe that language and thought are mutually independent.However,others believe that language and thought are inseparable.Beginning from Sapir-Whorf hypothesis and their theory of linguistic determinism and linguistic relativity,this article agrees with the influence of language over thought but refutes the extreme viewpoint of linguistic determinism from several points,proving the independence and mutual influence of language and thought.This article finally concludes that the preferred relationship between language and thought should be that they are independent but interactive. 展开更多
关键词 LANGUAGE THOUGHT Linguistic determinism INTERACTIVE INDEPENDENT
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The Influence Mechanism of an Inclusive Organizational Climate on Innovation Input of Sci-Tech Talents
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作者 Yang Xiaoyi Zhao Weihong Ma Xiaomeng 《Contemporary Social Sciences》 2024年第2期52-66,共15页
With the implementation of China’s innovation-driven development strategy,the competition among sci-tech talents has become increasingly fierce.Stimulating the innovative vigor of sci-tech talents has become a hot to... With the implementation of China’s innovation-driven development strategy,the competition among sci-tech talents has become increasingly fierce.Stimulating the innovative vigor of sci-tech talents has become a hot topic in theoretical research and policy practice.Based on the data from 246 questionnaires collected from sci-tech talents in Hebei province,this study explored the influence mechanism of an inclusive organizational climate on innovation input from technological talents and verified the mediating effects of innovation self-efficacy and intrinsic motivation.The results indicate that an inclusive organizational climate has a significant positive impact on innovation input,innovation self-efficacy,and intrinsic motivation of sci-tech talents.Both innovation self-efficacy and intrinsic motivation play a partial mediating role between an inclusive climate and innovation input.This study verified the important role of an inclusive climate in an organization’s human resource management practices and encouraged managers to emphasize enhancing the innovation self-efficacy and intrinsic motivation of sci-tech talents,thereby continuously improving the level of innovation. 展开更多
关键词 inclusive climate innovation self-efficacy intrinsic motivation sci-tech talents
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TOEPLITZ DETERMINANTS IN ONE AND HIGHER DIMENSIONS
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作者 Surya GIRI S.Sivaprasad KUMAR 《Acta Mathematica Scientia》 SCIE CSCD 2024年第5期1931-1944,共14页
In this study,we derive the sharp bounds of certain Toeplitz determinants whose entries are the coefficients of holomorphic functions belonging to a class defined on the unit disk U.Furthermore,these results are exten... In this study,we derive the sharp bounds of certain Toeplitz determinants whose entries are the coefficients of holomorphic functions belonging to a class defined on the unit disk U.Furthermore,these results are extended to a class of holomorphic functions on the unit ball in a complex Banach space and on the unit polydisc in C^(n).The obtained results provide the bounds of Toeplitz determinants in higher dimensions for various subclasses of normalized univalent functions. 展开更多
关键词 holomorphic mappings starlike mappings Toeplitz determinants coefficient inequalities
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Rabies by Dog Bites in Benin: Determinants of Good Knowledge of the Rabies Risk among Subjects Exposed in the Plateau Department in 2023
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作者 Benoit Sedegnon Agossoukpe Finagnon Armand Wanvoegbe +6 位作者 Georgia Barikissou Ignace Coovi Nonwanou Tokpanoude Elvire Se Djossou Phinées Adegbola Gilchrist Mègnisse Orphé Laly Tagnon Gautier Raphaël Gnonlonfoun Badirou Aguemon 《Open Journal of Epidemiology》 2024年第2期378-396,共19页
Rabies, a viral zoonosis, is one of the neglected tropical diseases (NTDs) that mainly affects poor and vulnerable populations. Human rabies is endemic in Benin. Although listed among the notifiable diseases, it never... Rabies, a viral zoonosis, is one of the neglected tropical diseases (NTDs) that mainly affects poor and vulnerable populations. Human rabies is endemic in Benin. Although listed among the notifiable diseases, it nevertheless remains a neglected and under-reported disease. The objective of this study was to investigate the determinants of knowledge of rabies risk among subjects exposed to human rabies by dog bites in the Plateau department of Benin. Methods: This was a cross-sectional study with an analytical aim which involved a sample of 900 people aged at least 18 years old chosen randomly and residing in the Plateau department for at least six months. A pre-tested and validated digital questionnaire served as a data collection tool. Data analysis was done with R 3.4.1 software. The prevalence ratio was used as a measure of association. The confidence threshold was set at 5%. We carried out a multiple logistic regression using the likelihood ratio (top-down approach) in order to identify the main factors which influenced the good knowledge of human rabies in the population of Plateau. Results: In the study population, 80.89% of the subjects surveyed lived in a rural area. The sex ratio (Male/Female) was 1.11. The average age of the subjects was 40.24 ± 14.52 years. The prevalence of dog bites was 4.11% (95% CI = [3.00;5.63]) or 37 subjects bitten. After evaluation of knowledge of rabies risk in the study population, the main factors which positively influenced good knowledge of human rabies were age (p linear trend 0.01), residence of the subject in the municipality of Pobè (ORa = 8.34;95% CI = 0.83 - 1.23;p < 0.01), individual dwelling (ORa = 17.95;95% CI = 13.12 - 49.58;p < 0. 01), educational level of at least secondary (ORa = 5.53;CI 95 = 3.06 - 10.15;p = 0.01), the existence of a veterinary center (ORa = 3.66;CI 95 = 1.07 - 12.43 p = 0.01) and knowledge of a dog bites victim (ORa = 6.55;95% CI = 2.73 - 8.25;p < 0.01). Conclusion: This population study confirms that human rabies remains a public health problem with a need to raise awareness among populations on good prevention practices against human rabies after a dog bite in the Plateau department. This could help to improve strategies surveillance for the control and eradication of human rabies through the implementation of the One Health approach. 展开更多
关键词 RABIES determinants KNOWLEDGE Associated Factors BENIN
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Unintended Pregnancy Determinants among Antenatal Clinic Attendees: A University of Port Harcourt Teaching Hospital Experience
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作者 Ijeoma Chioma Oppah Terhemen Kasso Emmanuel Okwudili Oranu 《Journal of Biosciences and Medicines》 2024年第4期229-245,共17页
An unintended pregnancy is a pregnancy that is either mistimed or unplanned. The objectives of this study were to determine the prevalence of unintended pregnancy as well as to document the determinant factors among p... An unintended pregnancy is a pregnancy that is either mistimed or unplanned. The objectives of this study were to determine the prevalence of unintended pregnancy as well as to document the determinant factors among pregnant women attending antenatal clinics at the University of Port Harcourt Teaching Hospital (UPTH), Port Harcourt, Rivers State, Nigeria. It was a descriptive, cross-sectional study of 215 women attending the antenatal clinic of UPTH from July to August 2022. Information on socio-demographic characteristics, reproductive history, desirability of the current pregnancy at the time of conception, knowledge and use of contraceptive methods were collected using a pretested questionnaire and analyzed using SPSS version 26.0. Chi-square test was used for test of associations with the level of significance set at P < 0.05. The prevalence rate of unintended pregnancy from the study was 16.28% (≈16%). The contraceptive awareness was very high (209, 97.21%), however, 101 (46.98%) participants had never used any form of contraceptives. Univariate analysis using Chi-square test showed a statistically significant association between age and unintended pregnancy (P = 0.042), level of education and unwanted pregnancy (P = 0.033) as well as parity and unintended pregnancy (P = 0.019). The prevalence of unintended pregnancy among women attending antenatal clinics was high, possibly due to low contraceptive usage. More efforts should be geared towards ensuring access to comprehensive contraceptive care and contraceptive methods, this will enhance uptake and reduce the rate of unintended pregnancy. 展开更多
关键词 Unintended Pregnancy determinants PREVALENCE Antenatal Attendees
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Determinants of Early Survival of Breast Cancer Patients in Yaoundé-Cameroon
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作者 Um Esther Meka Ngo Junie Annick Metogo Ntsama +4 位作者 Kodoumé Motolouze Naomi Marie Laurene Ndtoungou Schouame Obalemba Etienne Atenguena Claude Cyrille Noa Ndoua Robinson Enow Mbu 《Open Journal of Obstetrics and Gynecology》 2024年第3期487-501,共15页
Introduction: Breast cancer is one of the leading causes of death worldwide. We carried out this study with the aim of evaluating the determinants of early survival of women with breast cancer in two hospitals in the ... Introduction: Breast cancer is one of the leading causes of death worldwide. We carried out this study with the aim of evaluating the determinants of early survival of women with breast cancer in two hospitals in the city of Yaoundé. Methodology: This was an analytical cross-sectional study with retrospective and prospective data collection of breast cancer patients during 6 years in two Hospitals of Yaoundé from January 2017 to December 2022. We consulted the files in search of epidemiological, clinical, paraclinical, therapeutic and survival variables. We completed the survival data directly from the patients or their relatives after their consent. We analyzed the data using SPSS version 23.0 software. Survival analysis was done using the Kaplan-Meier method and survival curves were compared using the Log Rank test. Factors influencing survival were evaluated using the Cox model. The significance threshold (P value) was set at 0.05 at 95% confidence interval. The study was approved by the ethics committees. Results: We included 500 patients whose ages varied between 22 and 83 years with a mean age of 47.19 ± 11.61 years. The most represented age group was 30 to 45 years old (45.8%). Less than half (41.6%) were postmenopausal. The most frequent reason for consultation was a breast lump (79.9%). The most common clinical stage at presentation was stage-3 (47.6%). Infiltrating ductal carcinoma was the most represented histological type (84.7%). The most represented histological grade was grade 2 (40.2%). Immunohistochemistry was performed in 34.20% of cases. The most represented molecular subtype was triple negative (41.8%) followed by Luminal A (30%). Concerning treatment, 17.2% did not receive any, 45% had surgery, 79.4% had chemotherapy, 34.2% hormone therapy, and 14.6% radiotherapy. The survival of patients with breast cancer at 1, 2, 3, 4 and 5 years was respectively 90.6%;83.1%;74.2%;69.8% and 59.2%. The median survival was not reached;however, the first quartile (Q1) was 36 months (3 years). Independent factors associated with reduced survival were breast ulceration (aHR = 3.23;p = 0.002), bilateral tumor location (aHR = 9.2;p < 0.001) and clinical stage 3 (aHR = 1.72;p = 0.010) while patients classified ACR3 on imaging (aHR = 0.19;p = 0.005) had improved survival. Conclusion: Breast cancer survival from 1 to 5 years decrease from 90 to 59%. Mortality was highest in the first 40 months. Independent factors associated with reduced survival were breast ulceration, bilateral tumor location and clinical stage 3 while patients classified ACR3 on imaging had improved survival. 展开更多
关键词 determinants Early Survival Breast Cancer Yaoundé
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Silencing transformer and transformer-2 in Zeugodacus cucurbitae causes defective sex determination with inviability of most pseudomales
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作者 Qin Ma Zizhen Fan +5 位作者 Ping Wang Siya Ma Jian Wen Fengqin Cao Xianwu Lin Rihui Yan 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第3期938-947,共10页
transformer is a switch gene for sex determination in many insects, which cooperates with transformer-2 that is expressed in both sexes to regulate female differentiation, particularly in dipterans. Zeugodacus cucurbi... transformer is a switch gene for sex determination in many insects, which cooperates with transformer-2 that is expressed in both sexes to regulate female differentiation, particularly in dipterans. Zeugodacus cucurbitae(Coquillett) is a very destructive pest worldwide, however, its sex determination pathway remains largely uncharacterized. Here, we show that the female sex ratio is sharply reduced with knockdown of either transformer or transformer-2 by RNA interference in early embryos of Z. cucurbitae. Most of the males grown from the embryos with transient transformer and transformer-2 suppression mated with wild-type females and produced mixed sex progeny, with one exception that produced only female progeny, and all of the few remaining males failed to mate with wild-type females and produced no progeny. The exceptional male and those males with mating failure were XX pseudomales as determined by the detection of Y chromosome-linked Maleness-on-the-Y, indicating that most XX pseudomales are not viable. The phenotypes of transformer and transformer-2 suggest that they play a key role in regulating sex determination and are required for female sexual development of Z. cucurbitae. Our results will be beneficial to the understanding of sex determination in Z. cucurbitae and can facilitate the development of genetic sexing strains for its biological control. 展开更多
关键词 Zeugodacus cucurbitae TRANSFORMER transformer-2 sex determination RNA interference biological control
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Relative orbit determination algorithm of space targets with passive observation
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作者 DAI Chenchao QIANG Hongfu +2 位作者 ZHANG Degang HU Shaolei GONG Baichun 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2024年第3期793-804,共12页
Angles-only relative orbit determination for space non-cooperative targets based on passive sensor is subject to weakly observable problem of the relative state between two spacecraft. Previously, the evidence for ang... Angles-only relative orbit determination for space non-cooperative targets based on passive sensor is subject to weakly observable problem of the relative state between two spacecraft. Previously, the evidence for angles-only observability was found by using cylindrical dynamics, however, the solution of orbit determination is still not provided. This study develops a relative orbit determination algorithm with the cylindrical dynamics based on differential evolution. Firstly, the relative motion dynamics and line-of-sight measurement model for nearcircular orbit are established in cylindrical coordinate system.Secondly, the observability is qualitatively analyzed by using the dynamics and measurement model where the unobservable geometry is found. Then, the angles-only relative orbit determination problem is modeled into an optimal searching frame and an improved differential evolution algorithm is introduced to solve the problem. Finally, the proposed algorithm is verified and tested by a set of numerical simulations in the context of highEarth and low-Earth cases. The results show that initial relative orbit determination(IROD) solution with an appropriate accuracy in a relative short span is achieved, which can be used to initialize the navigation filter. 展开更多
关键词 angles-only measurement relative orbit determination cylindrical coordinate differential evolution
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The Role of Electrocardiogram DETERMINE Score in Prediction of Coronary Artery Disease Severity
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作者 Ismail N. El-Sokkary Essam Ahmed Khalil +5 位作者 Mohammed Wael Badawi Ibrahim K. Gamil Shousha Abdalla A. Elsebaey Mohamed Kamal Rehan Mahmoud Ibrahim Elshamy Yasser Ahmed Sadek 《World Journal of Cardiovascular Diseases》 CAS 2024年第9期567-580,共14页
Background: A major cause of mortality and disability on a global scale is myocardial infarction (MI). These days, the most reliable way to detect and measure MI is via cardiovascular magnetic resonance imaging (CMR).... Background: A major cause of mortality and disability on a global scale is myocardial infarction (MI). These days, the most reliable way to detect and measure MI is via cardiovascular magnetic resonance imaging (CMR). Aims and Objectives: To evaluate the effectiveness of the Electrocardiogram DETERMINE Score in predicting the severity of coronary artery disease (CAD) in patients who have experienced an Acute Myocardial Infarction (AMI) & to assess improvements in left ventricular function at 6 months following coronary artery bypass grafting (CABG). Subjects and Methods: This Observational cohort study was done at the Cardiology and Radiology department and cardiac surgery department, Al-Azhar university hospitals and Helwan University hospital. The study involved 700 cases who patients diagnosed with Acute Myocardial Infarction and fulfilled specific criteria for selection. Result: There was highly statistically significant relation between Myocardial infarction size and ECG Marker Score as mean infarct size elevated When the number of ECG markers increased. There was a highly statistically significant relation between myocardial infarct segments, myocardial infarction size and improvement of cardiac function 6 months post-CABG. Conclusion: The study found that larger myocardial infarctions corresponded with higher DETERMINE Scores. It concluded that an ECG-based score better estimates infarct size than LVEF alone. Additionally, there was a significant statistical correlation between the size and segmentation of myocardial infarction and better cardiac function six months after CABG. 展开更多
关键词 Electrocardiogram determinE Score Coronary Artery Disease OUTCOME Acute Myocardial Infarction Coronary Artery Bypass Grafting
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