By analyzing the questionnaires recollected from 74 different government departments in Chengdu, China, an evaluation model for scientific quality of civil servants was developed with the rough set theory. In the empi...By analyzing the questionnaires recollected from 74 different government departments in Chengdu, China, an evaluation model for scientific quality of civil servants was developed with the rough set theory. In the empirical study, a series of important rules were given to help to check and forecast the degree of the scientific quality of civil servants by using the reduction algorithm, and the total accuracy of prediction was 93.2%.展开更多
Animal models are crucial for the study of severe infectious diseases,which is essential for determining their pathogenesis and the development of vaccines and drugs.Animal experiments involving risk grade 3 agents su...Animal models are crucial for the study of severe infectious diseases,which is essential for determining their pathogenesis and the development of vaccines and drugs.Animal experiments involving risk grade 3 agents such as SARS CoV,HIV,M.tb,H7N9,and Brucella must be conducted in an Animal Biosafety Level 3(ABSL-3)facility.Because of the in vivo work,the biosafety risk in ABSL-3 facilities is higher than that in BSL-3 facilities.Undoubtedly,management practices must be strengthened to ensure biosafety in the ABSL-3 facility.Meanwhile,we cannot ignore the reliable scientific results obtained from animal experiments conducted in ABSL-3 laboratories.It is of great practical significance to study the overall biosafety concepts that can increase the scientific data quality.Based on the management of animal experiments in the ABSL-3 Laboratory of Wuhan University,combined with relevant international and domestic literature,we indicate the main safety issues and factors affecting animal experiment results at ABSL-3 facilities.Based on these issues,management practices regarding animal experiments in ABSL-3 facilities are proposed,which take into account both biosafety and scientifically sound data.展开更多
基金Doctoral Fund of Ministry of Educationof China (No20060613019)
文摘By analyzing the questionnaires recollected from 74 different government departments in Chengdu, China, an evaluation model for scientific quality of civil servants was developed with the rough set theory. In the empirical study, a series of important rules were given to help to check and forecast the degree of the scientific quality of civil servants by using the reduction algorithm, and the total accuracy of prediction was 93.2%.
基金We are grateful for the funding from the National Key Research and Development Program of China(grant No.:2016YFC1202203).
文摘Animal models are crucial for the study of severe infectious diseases,which is essential for determining their pathogenesis and the development of vaccines and drugs.Animal experiments involving risk grade 3 agents such as SARS CoV,HIV,M.tb,H7N9,and Brucella must be conducted in an Animal Biosafety Level 3(ABSL-3)facility.Because of the in vivo work,the biosafety risk in ABSL-3 facilities is higher than that in BSL-3 facilities.Undoubtedly,management practices must be strengthened to ensure biosafety in the ABSL-3 facility.Meanwhile,we cannot ignore the reliable scientific results obtained from animal experiments conducted in ABSL-3 laboratories.It is of great practical significance to study the overall biosafety concepts that can increase the scientific data quality.Based on the management of animal experiments in the ABSL-3 Laboratory of Wuhan University,combined with relevant international and domestic literature,we indicate the main safety issues and factors affecting animal experiment results at ABSL-3 facilities.Based on these issues,management practices regarding animal experiments in ABSL-3 facilities are proposed,which take into account both biosafety and scientifically sound data.