The sedimentation rates in the Okinawa Trough during the Late Quaternary

On the basis of accelerator mass spectrometer radiocarbon （AMS ^14C） dating, sedimentation rates of 11 cores collected from the northern to southern Okinawa Trough are discussed. The sedimentation rates in the Okinawa Trough roughly range from 11 to 39cm/ka, and the average is 23.0cm/ka. China＇s continental matter is the main sediment source of the middle Okinawa Trough and has important contribution to the northern and southern Okinawa Trough. The sedimentation rates during the marine oxygen isotope （MIS） 2 are uniformly higher than those during MIS 1 in the northern and middle Okinawa Trough while they are on the contrary in the southern Okinawa Trough. Sedimentation rates in the Okinawa Trough can be one of the proxies of sediment source and an indicator of cooling events.

Sedimentation rates in the Wanggang salt marshes,Jiangsu

Coastal salt-marshes represent an important coastal wetland system. The total area of coastal wetlands exceeds 5000 km2 in Jiangsu Province, China, but it is decreasing rapidly in response to the intense reclamation activities and coastal erosion along a part of the coastline. Hence, two types of plants, Spartina angelica and Spartina alterniflora, were introduced successively into the Jiangsu coastal areas, in order to protect the coastline from erosion and to increase the accumulation rate. Pb-210 and Cs-137 analyses were carried out for sediment samples from the salt-marshes of Wanggang to determine the sedimentation rate, on the basis of an evaluation of the background activity values and the factors affecting the enrichment of Pb-210. Analysis of a typical sediment column of the tidal flat shows that there is weak absorption of Pb-210 in the silt-dominated sediment. Because of the influences of factors such as storm events, bioturbation, material sources and analytical error, some abnormal data points appear in the Pb-210 record. After ignoring these data the calculated sedimentation rate was 3.3 cm yr-1 on average. Based upon analysis of the Cs-137 dating, the rate since 1963 was 3.1 cm yr-1 on average, similar to the data by Pb-210 dating and the previous studies. The dating results show that there were three stages of sedimentation, with the most rapid accretion being taking place after Spartina angelica was introduced into the area. The study also shows that at the stage of Spartina alterniflora growth, the accretion rate was higher than on the flat surface with the same elevation without the cover of this plant.

Determination of sedimentation rates in Izmir Bay using ^(210)Pb radionuclide

In this study, using the constant rate of supply model, sedimentation rates of Izmir Bay were calculated and discussed. For this purpose, eight sediment cores were collected from inner part of the bay and sedimentation rates were calculated from vertical distribution of^(210)Pb.^(210)Pb activities were determined indirectly from ^(210)Po activities.Sedimentation rates ranged from 0.10 to 0.52 cm/year. The highest sedimentation rates were determined in stations close to the Poligon stream. It was concluded that main transporting mechanism for sediments is river and streams in the area. In addition, sediment cores taken from the harbor were mixed due to bioturbation, water circulation and/or other factors.

Modern sedimentation rates in the intertidal zone on the west coast of the Bohai Gulf

On the basis of the measurement of 210Pbex and 137Cs activities in the sediment cores taken from the intertidal zone on the west coast of the Bohai Gulf, the average sedimentation rates of modern sediments are calculated. The results indicate that in the sandy area of the intertidal zone (from Daogouzi to the Duliujian River), the sedimentation rate from 1955 to 1963 is 3.43-4.06 cm/a, and is within the range of 0.65￣1.59 cm/a since 1963. The average sedimentation rate in the muddy area (around Qikou) is approximately 1.81 cm/a. The results above suggest that the sandy area of the intertidal zone has experienced rapid sedimentation from the 1950s to the 1960s, and the sedimentation slows down after the 1960s, and the sedimentation rates increase from north to south spatially. The rapid sedi- mentation from the 1950s to the 1960s in the sandy area is due to the fact that North China has plentiful precipitation during this period and the intertidal zone is supplied with abundant matter sources for sedimentation. After the 1960s, the weakened sedimentation may be a result of the reduction of sand transported to the intertidal zone, which is a consequence of diminished rainfall in North China and intensive human activities in the Haihe basin.

MODERN SEDIMENTATION RATES AND SEDIMENTATION FEATURE IN THE HUANGHE RIVER ESTUARY BASED ON ^(210)Pb TECHNIQUE

Based on Pb technique, sedimentation rates of 11 cores collected from the Huanghe River estuary were determined. CaCO3 distribution of 4 cores chosen from among these was measured. Profiles of 210Pb in the cores showed that the distribution of 210Pb activity decayed with depth, appeared in stages and in more than one segment. The sedimentation rates,210Pb and CaCO3 data have similar distribution trend in the 4 cores. Jhe profiles of Pb and CaCO3 were used to study sedimentation in -tensity, transportation trend of material and sedimentation features in the coring area.

Investigation of the Clinical Diagnostic Significance of the T-Cell Test for Tuberculosis combined with Erythrocyte Sedimentation Test in Pulmonary Tuberculosis

Objective:To investigate the clinical diagnostic significance of peripheral blood T-cell test(T-spot test)for tuberculosis(TB)infection combined with erythrocyte sedimentation rate(ESR)in pulmonary TB.Methods:41 patients with a clinical diagnosis of TB during hospitalization from January 2020 to April 2023 in our hospital were selected as the experimental group,and 45 patients without TB(bronchopneumonia patients)were selected as the control group.The diagnostic specificity,sensitivity,and accuracy of the T-spot TB test,ESR test,and the combined test of the two were calculated respectively.Results:The sensitivity,specificity,and accuracy of the T-spot TB test combined with ESR for the diagnosis of TB in the experimental group were significantly higher than the individual results of the T-spot TB test and ESR test alone(P<0.05).Conclusion:The T-spot TB test combined with the ESR test for TB diagnosis has greater clinical value than carrying out the tests individually.

Human-induced changes in recent sedimentation rates in Bohai Bay, China： Implications for coastal development

In many countries, coastal planners strive to balance the demands between civil, commercial strategy and environmental conversation interests for future development, particularly given the sea level rise in the 21 st century. Achieving a sustainable balance is often a dilemma, especially in low-lying coastal areas where dams in inland river basin are trapping significant amounts of fluvial sediments. We recently investigated the shore of Bohai Bay in northern China where there has been a severe increase in sea level following a program of large-scale coastal reclamation and infrastructure development over the last five decades. To investigate this trend, we obtained sediment cores from near-shore in Bohai Bay, which were dated by ^(137)Cs and ^(210)Pb radionuclides to determine the sedimentation rates for the last 50 years. The average sedimentation rates of Bohai Bay exceeded 10 mm yr^(-1) before 1963, which was much higher than the rate of local sea-level rise. However, our results showed an overall decreasing sedimentation rate after 1963, which was not able to compensate for the increasing relative sea-level rise in that period. In addition, our results revealed that erosion occurred after the 1980 s in the shallow sea area of Bohai Bay. We suggest that this situation places the Bohai Bay coast at a greater risk of inundation and erosion within the next few decades than previously thought, especially in the large new reclamation area. This study may be a case study for many other shallow sea areas of the muddy coast if the sea level continues to rise rapidly and the sediment delivered by rivers continues to decrease.

Effects of Different Cations on the Flocculation and Sedimentation of Static Fine-Grained

Natural water bodies mostly contain cations,and the type and content of these cations are the main factors affecting the flocculation of fine-grained cohesive sediments and the floc sedimentation rate at the interface between clear and turbid water.From the microscopic aspect,this study examined the changing patterns of porosity and the fractal dimension of the flocs of fine-grained cohesive sediments.Sedimentation experiments under different sediment contents and electrolyte conditions were conducted,and microscopic images of the flocs were analysed using Image-Pro Plus(IPP)and MATLAB based on the fractal theory.From the macroscopic aspect,this study experimentally investigated the flocculation and sedimentation of fine-grained cohesive sediments and proposed a sedimentation rate equation by introducing an ion concentration-related parameter into an existing sedimentation rate equation(stagnation zone)based on the adsorption isotherm equation.The equation proposed in this study was validated with measured data.The calculated values were in good agreement with the measured values,with a relative error of 16%.The findings of this study provide a reference for further research on the flocculation and sedimentation of fine-grained cohesive sediments in different water bodies.

Clinical efficacy and safety of flexible ureteroscopy and percutaneous nephrolithotomy for large kidney stones:A retrospective comparative study

BACKGROUND Renal stones ranging 20–40 mm are very common in China.Although no largesample clinical studies have confirmed the clinical efficacy and safety of this method,there is also a lack of comparative data with traditional treatment.AIM To investigate the clinical efficacy of flexible ureteroscopy(FURS)and percutaneous nephrolithotomy(PCNL)by postoperative stone clearance and changes in soluble vascular cell adhesion molecule 1(sVCAM-1)and kidney injury molecule 1(KIM-1)levels in patients with large kidney stones(>2 cm in diameter).METHODS This single-center observational study was performed at a Chinese hospital between January 1,2021,and October 30,2023.All 250 enrolled patients were diagnosed with large kidney stones(>2 cm)and divided into a FURS group(n=145)and a PCNL group(n=105)by the surgical method.The FURS group was treated with flexible ureteroscopy and the PCNL group was treated with percutaneous nephrolithotomy.The operation time,time to palinesthesia,intraoperative blood loss,drop in hemoglobin,length of hospital stay,stone clearance rate,and complications were recorded in the two groups.Preoperative and postoperative serum sVCAM-1 levels,erythrocyte sedimentation rate(ESR),urine KIM-1 levels,preoperative and postoperative pain visual analog scale(VAS)and Wisconsin Stone Quality of Life Questionnaire(WISQOL)scores were also documented.RESULTS All 250 eligible patients completed the follow-up.There were no significant differences in baseline characteristics between the two groups(P>0.05).The operation time in the FURS group was significantly greater than that in the PCNL group.The time to ambulation,intraoperative blood loss,decrease in hemoglobin,and length of hospital stay were significantly lower in the FURS group than in the PCNL group.The FURS group also had a significantly higher stone clearance rate and a lower incidence of postoperative complications.There was no significant difference in antibiotic use between the groups.Postoperative serum sVCAM-1 levels,urine KIM-1 levels,and VAS scores were lower in the FURS group than in the PCNL group,but postoperative ESR and WISQOL scores were greater in the FURS group than in the PCNL group.CONCLUSION FURS demonstrated superior clinical efficacy in treating large kidney stones(>2 cm in diameter)compared PCNL.It not only improved the postoperative stone clearance rate and reduced complications and recovery time but also positively affected serum SCM-1,ESR,and urine KIM-1 levels,subsequent improvement of patient quality of life.

Sedimentation and morphological changes at Yuantuojiao Point, estuary of the North Branch, Changjiang River

The North Branch, separated by the Chongming Island, was once the main channel in the estuary of the Changjiang River. Reclamation and a decrease in runoffto the North Branch had led to the narrowing and shallowing of the channel. The Yuantuojiao Point is located at the intersecting point connecting the North Branch of the Changjiang River and the Jiangsu coastline. Erosion cliffs are developed between the typical silty-muddy tidal flat and the salt marsh occupied by Spartina alterniflorea, and this has changed rapidly over the past few years. The sediment grain size analysis results of the surficial and two core samples indi- cate that the Yuantuoiiao Point tidal fiat experienced continuous accretional processes. Based upon 137Cs analysis results of the YT and YY Cores sampled from the tidal flat at the Yuantuojiao Point, the average sed- imentation rate of the YT Core was 2.30 cm/a from 1963 to 2007, and 2.38 cm/a from 1954 to 2007 for the YY Core. The sedimentation rates of both core locations have declined since the 1960s corresponding to the seaward reclamation at the Yuantuojiao Point. The average sedimentation rates at the Yuantnojiao Point were similar to that of the silty-muddy tidal flat at the northern ]iangsu coast, but lower than that of the south of the Changjiang River Estuary. According to field morphological investigations from 2006 to 2008 on the salt marsh at the Yuantuojiao Point, cliffs retreated markedly by storm surges and disappeared gradu- ally because of the rapid sedimentation on the silty-muddy tidal flat. The maximum annual retreat reached 10 m. The recent sedimentation and morphological changes of the Yuantuojiao Point tidal flat not only displayed the retreat of the salt marsh and the disappearance of cliffs, but also was accompanied by rapid sedimentation of the silty-muddy tidal flat and the salt marsh, indicating the responses to the tidal currents, storm surges, Spartina alterniflorea trapping sediments and large-scale reclamation. The sediment grain size and their trends, southward coastal flow, and sandspits of the longshore bars suggest that the main sediment source at the Yuantuoijao Point, estuary of the North Branch was possibly from the Changjiang River before 1958, since then, it has been from the south of the submarine radial sand ridges of the southern Huanghai Sea （Yellow Sea）.

Late Quaternary terrigenous sedimentation in the Western Arctic Ocean as exemplified by a sedimentary record from the Alpha Ridge

Terrigenous components in sediment core B84A from the Alpha Ridge, Western Arctic Ocean, have been investigated to reconstruct Mid to Late Quaternary variations in sedimentation, provenance, and related climate changes. The core stratigraphy, evaluated by a combination of variations in Mn content, color cycles, foraminiferal abundance, and lithological correlation, extends back to estimated Marine Isotope Stage 12. Twelve Ice Rafted Detritus （IRD, 〉250 ttm） events were identified and interpreted to mostly occur during deglaciation. The Canadian Arctic, which was covered by ice sheets during glacial periods, is suggested to be the major source region. The IRD events likely indicate the collapses of ice sheets, possibly in response to abrupt climate changes. Grain size analysis of B84A indicates sedimentologically sensitive components in core B84A in the 4 9 #m and 19 53/~m silt subfractions, which are inferred to be mainly transported by currents and sea ice, respectively. Down core variability of these two fractions may indicate changes in ice drift and current strength. In accordance with previous studies in the central Arctic Ocean, the average sedimentation rate in core B84A is about 0.4 cm.ka-1. Compared with the relatively high sedimentation rates on the margins, sedimentation in the central Arctic Ocean is limited by sea ice cover and the correspondingly low bioproductivity, as well as the long distance from source regions of terrigenous sediment.

Settlement prediction model of slurry suspension based on sedimentation rate attenuation

This paper introduces a slurry suspension settlement prediction model for cohesive sediment in a still water environment. With no sediment input and a still water environment condition, control forces between settling particles are significantly different in the process of sedimentation rate attenuation, and the settlement process includes the free sedimentation stage, the log-linear attenuation stage, and the stable consolidation stage according to sedimentation rate attenuation. Settlement equations for sedimentation height and time were established based on sedimentation rate attenuation properties of different sedimentation stages. Finally, a slurry suspension settlement prediction model based on slurry parameters was set up with a foundation being that the model parameters were determined by the basic parameters of slurry. The results of the settlement prediction model show good agreement with those of the settlement column experiment and reflect the main characteristics of cohesive sediment. The model can be applied to the prediction of cohesive soil settlement in still water environments.

Sedimentation Processes and Useful Life of Mosul Dam Reservoir, Iraq

The sedimentation process is the most important problems that affects directly the performance of reservoirs due to the reduction of the storage capacity and possible problems effecting the operation. Thus periodic assessment of the storage capacity and determining sediment deposition patterns is an important issue for operation and management of the reservoirs. In this study, bathymetric survey results and an analytical approach had been used to assess the characteristics of sedimentation and estimate the useful life of Mosul Reservoir. It is located on the Tigris River in the north of Iraq. The water surface area of its reservoir is 380 km2 with a designed storage capacity of 11.11 km3 at a maximum operating level (330 m a.s.l). The dam started operating in 1986. No detailed study was yet carried out to assess its reservoir. The present study indicated that the annual reduction rate in the dead and live storage capacities of the reservoir is 0.786% and 0.276% respectively. The observed results (bathymetric survey) and algebraic formula show approximately that the useful life of Mosul dam reservoir is about 125 years. Furthermore, the stage-storage capacity curves for the future periods (prediction curves) were established using bathymetric survey data.

Relationship between reference value (Wintrobe) of Chinese people's erythrocyte sedimentation rate (ESR) and geographical factors

In order to provide a scientific basis for laying out a unified standard of the reference value (Wintrobe) of Chinese people's erythrocyte sedimentation rate (ESR). this paper studies the relationship between the reference values (Wintrobe) of Chinese healthy people's ESR, and the test is done according to the Wintrobe Laws and five geographical factors. It is found that the altitude is the modt important factor affecting the reference value (Wintrobe) of Chinese people's ESR. As altitude increases gradually, the reference value (Wintrobe) of people's ESR decreases accordingly, the correlation is quite obvious. By using the method of regression analysis, two multivariate regression equations and ten univariate regression equations are deduced If the geographical index values in a particular area are known, the reference value (Wintrobe) of Chinese people's ESR of this region can be established by means of the regression equations. Furthermore, according to the dependent relationship of the reference value (Wintrobe) of Chinese people's ESR on geographical factors.China can be divided into sin districts: Qinghai-Tibet, Southwest. Northwest. Southeast, North and Northeast China.

A New Method to Predict Erythrocyte Sedimentation Rate with Natural Geographical Factors and Location by Case-based Reasoning: A Case Study of China

Reference values of erythrocyte sedimentation rate(ESR)are the key to interpret ESR blood test in clinic.The common local reference ESR values are more accuracy in blood test that are established with natural geographical factors by using the multiple linear regression(MLR)model and the artificial neural network(ANN).These knowledge-based methods have limitations since the knowledge domains of ESR and natural geographical factors are limited.This paper presents a new cases-depended model to establish reference ESR values with natural geographical factors and location using case-based reasoning(CBR)since knowledge domain of ESR and geographical factors is weak.Overall 224 local normal ESR values of China that calculated from 13623 samples were obtained,and the corresponding natural geographical factors and location that include altitude,sunshine hours,relative humidity,temperature,precipitation,annual temperature range and annual average wind speed were obtained from the National Geomatics Center of China.CBR was used to predict the unseen local reference ESR values with cases.The average absolute deviation(AAD),mean square error(MSE),prediction accuracy(PA),and Pearson correlation coefficient(r)between the observed and estimated data of proposed model is 33.07%,9.02,66.93% and 0.78,which are better than those of ANN and MLR model.The results show that the proposed model provides higher prediction accuracy than those of the artificial neural network and multiple linear regression models.The predicted values are very close to the observed values.Model results show significant agreement of cases data.Consequently,the model is used to predict the unseen local reference ESR with natural geographical factors and location.In spatial,the highest ESR reference areas are distributed in the southern-western district of China that includes Sichuan,Chongqing,Guangxi and Guizhou provinces,and the reference ESR values are greater than 23 mm/60 min.The higher ESR reference values are distributed in the middle part and northern-eastern of China which include Hubei,Henan,Shaanxi,Shanxi,Jilin and Heilongjiang provinces,and the reference ESR values are greater than 18 mm/60min.The lowest ESR reference values are distributed in the northern-western of China that includes Tibet and Xinjiang,and the reference ESR values are lower than 5 mm/60min.

Unexplained elevation of erythrocyte sedimentation rate in a patient recovering from COVID-19:A case report

BACKGROUND A disease caused by a novel coronavirus virus,named coronavirus disease 2019(COVID-19),broke out in Wuhan,China in December 2019,and spread around the word.As of March 4,2020,93090 confirmed cases and 2984 deaths have been reported in more than 80 countries and territories.It has triggered global public health security.However,the features and prognosis of COVID-19 are incompletely understood.CASE SUMMARY We here report that the erythrocyte sedimentation rate(ESR)increased in a confirmed COVID patient.The high level of ESR sustained for a long time even after the patient recovered from COVID-19,while all results related to tumor,tuberculosis,rheumatic diseases,anemia,etc.cannot explain the abnormal elevation of ESR presented in this case.CONCLUSION Although the increased ESR cannot be explained by all existing evidence,it possibly links the abnormal pathologic change in some COVID-19 patients and negative prognosis,and provides the clue to dissect the mechanism of illness progressing in COVID-19 and its prognosis.

Relevant detection indicator of prethrombotic state in patients with primary hypertension

BACKGROUND Hypertension is a common chronic disease that affects many people worldwide.Only a few reports related to the exploration of relevant indicators of the prethrombotic state in patients with primary hypertension(PH)in clinical settings were available.AIM To detect prethrombotic state-related indicators in patients with PH and analyze their differences in different patient populations to provide a laboratory basis for the clinical prevention and control of hypertensive thrombotic diseases.METHODS The general data of patients with PH who attended the Department of Cardiovascular Medicine,The First Affiliated Hospital of Jiangxi Medical College,from January 2022 to December 2022 were collected retrospectively.The patients were divided into three groups of 40 patients each according to the Grade of PH:Grade 1,Grade 2,and Grade 3 hypertension experimental group.The baseline data of 40 volunteers,who underwent physical examination in our hospital but were not diagnosed with PH during the same period,were included in the control group.The relevant indicators of prethrombotic state of the participants were compared,and mainly included inflammation-related indicators,hemorheology-related indicators,and coagulation function related indicators.The relationship between the aforementioned indicators and the progression of PH was analyzed.RESULTS No significant differences were observed in age,sex,diabetes mellitus,smoking history,drinking history,body mass index,New York Heart Association functional classification,or the course of hypertension among the four groups(P>0.05).The expressions of high-sensitivity C-reactive protein(hs-CRP),thrombomodulin(TM),hematocrit(Hct),erythrocyte sedimentation rate(ESR),P-selectin on platelet surface(CD62P),and fibrinogen(FIB)in the control group were<Grade 1 hypertension group<Grade 2 hypertension group<Grade 3 hypertension group,and the expressions of platelet(PLT),activated partial thromboplastin time(APTT),prothrombin(PT),and plasma thrombin time(TT)in the control group was>Grade 1 hypertension group>Grade 2 hypertension group>Grade 3 hypertension group,and the difference was statistically significant(P<0.05).The results of the multivariate logistic regression model showed that the expression of hs-CRP,TM,Hct,ESR,CD62P,PLT,APTT,PT,TT,and FIB in the included participants was related to the progression of PH.Among these,high expression of hs-CRP,TM,Hct,ESR,CD62P,APTT,PT,and TT,and low expression of PLT and FIB were risk factors for PH(OR>1,P<0.05).The results of the receiver operating characteristic curve analysis showed that the area under the curve of hs-CRP,TM,ESR,CD62P,APTT,PT,TT,and FIB for the prediction of PH were>0.80,and the prediction value was ideal.Linear correlation analysis with bivariate Spearman showed that hs-CRP,TM,Hct,ESR,CD62P,APTT,PT,and TT were positively correlated with each other(r>0,P<0.05);PLT and FIB were negatively correlated with hs-CRP,TM,Hct,ESR,CD62P,APTT,PT,and TT(r<0,P<0.05);and PLT and FIB were positively correlated(r>0,P<0.05).Linear correlation analysis using bivariate Spearman showed that hs-CRP,TM,Hct,ESR,CD62P,and FIB were positively correlated with each other(r>0,P<0.05),whereas PLT,APTT,PT,and TT were negatively correlated with hs-CRP,TM,Hct,ESR,CD62P,and FIB(r<0,P<0.05).There was a positive correlation between PLT,APTT,PT,and TT(r>0,P<0.05).CONCLUSION The relevant indicators of the prethrombotic state in patients with PH,such as hs-CRP,TM,Hct,ESR,CD62P,PLT,APTT,PT,TT,and FIB,showed differences.High expression of hs-CRP,TM,Hct,ESR,CD62P,and FIB,and low expression of PLT,APTT,PT,and TT are the keys to the occurrence,progression,and thrombotic state of PH.Based on the above serum indicators’expression in patients,targeted interventions can be administered to patients with abnormal expression levels to control the progression of their disease and reduce the risk of developing a prethrombotic state.

Musculoskeletal Ultrasonography for the Assessment of Combined Drug Therapy for Rheumatoid Arthritis

Background: To evaluate the effect of treatment on musculoskeletal ultrasound (MSUS) and explore whether MSUS are associated with therapeutic response in rheumatoid arthritis (RA) patients treated with Tofacitinib in combination with methotrexate (MTX). Methods: We enrolled 102 RA patients treated with Tofacitinib in combination with MTX from a multicenter, exploratory, short-term, prospective and observational ultrasound cohort study of patients who received biologic or targeted synthetic disease-modifying antirheumatic drug (DMARD) therapy. We evaluated the patients’ clinical disease activity and musculoskeletal ultrasound (MSUS) scores. The serum concentrations of two venous blood inflammatory indicators were evaluated (c-reactive protein [CRP], erythrocyte sedimentation rate [ESR]) by multiplex bead assays at baseline, 3, and 6?months: the change over 6?months was defined as the P value. Before MSUS score treatment, an associate chief physician tested the wrist joints of each patient at the first treatment, and the attending physician with 3 years of MSUS experience and 7 years of work experience also performed semi-quantitative scores on the same RA patients and tested the consistency of the results. Results: Tofacitinib in combination with MTX significantly improved the clinical disease activity and MSUS score over 6?months. Serum ESR and CRP were significantly elevated at 6?months after the Tofacitinib in combination with MTX introduction (P P P Conclusions: MSUS scores may be useful for predicting RA patients’ therapeutic responses to abatacept.

Cenozoic Evolution of Sediments and Climate Change and Response to Tectonic Uplift of the Northeastern Tibetan Plateau

Through a comprehensive study of magnetostratigraphy and sedimentology of several basins in the northeastern Tibetan Plateau,we reveal that the study area mainly experienced six tectonic uplift stages at approximately 52 Ma,34-30 Ma,24-20 Ma,16-12 Ma,8-6 Ma,and 3.6-2.6 Ma.Comprehensive analyses of pollen assemblages from the Qaidam,Linxia,Xining,and West Jiuquan Basins show that the northeastern Tibetan Plateau has undergone six major changes in vegetation types and climate：50-40 Ma for the warm-humid forest vegetation,40-23 Ma for the warm-arid and temperate-arid forest steppe vegetation,23-18.6 Ma for the warm-humid and temperate-humid forest vegetation,18.6-8.5 Ma for the warm-humid and cool-humid forest steppe vegetation,8.6-5 Ma for the temperate sub-humid savanna steppe vegetation,and 5-1.8 Ma for the cold-arid steppe vegetation.Comprehensive comparisons of tectonic uplift events inferred from sedimentary records,climatic changes inferred from pollen,and global climate changes show that in the northeastern Tibetan Plateau the climate in the Paleogene at low altitude was mainly controlled by the global climate change,while that in the Neogene interval with high altitude landscapes of mountains and basins is more controlled by altitude and morphology.

Distribution of ^137Cs and ^210Ppb in sediments of tidal flats in north Jiangsu Province

Seven cores were collected from different sediment zones of tidal flats at Xin- yanggang in north Jiangsu province in August 2007. Sediment grain-size distribution and radioisotopes of ^137Cs and ^210Ppb analysis were carried out for these cores. Sediment rates of the cores and radioisotopes distribution in surface sediment in different zones of the tidal flat were calculated from the ^137Cs and ^210Ppb activities in sediments cores. The results indicated that each tidal zone had experienced different evolution phases, hydrological dynamics in the tidal flats made the grain-size of the surface sediment change gradually. ^137Cs and ^210Ppb activities on the superficial layer of the cores varied spatially and the reason was discussed. On tidal flats, the fluctuation of ^137Cs and ^210Ppb activities in the cores reflected the special sedimentary characteristics. Vegetation affects the grain-size distribution and the vertical profiles of ^137Cs and ^210Ppb in the upper depths. ^137Cs and ^210Ppb chronology got the comparable average sediment rates on the tidal flat. The characteristics of ^137Cs and ^210Ppb in the cores reflected various depositional dynamical environments in different tidal zones and gave information on the different evolvement phases of the tidal zones. Based on the information of grain-size distribution, texture of the cores, sediment rates and topography, the evolution lines of the tidal flat were reconstructed.