Selecting the optimal one from similar schemes is a paramount work in equipment design.In consideration of similarity of schemes and repetition of characteristic indices,the theory of set pair analysis(SPA)is proposed...Selecting the optimal one from similar schemes is a paramount work in equipment design.In consideration of similarity of schemes and repetition of characteristic indices,the theory of set pair analysis(SPA)is proposed,and then an optimal selection model is established.In order to improve the accuracy and flexibility,the model is modified by the contribution degree.At last,this model has been validated by an example,and the result demonstrates the method is feasible and valuable for practical usage.展开更多
A modified selectively infective phage (SIP) is developed to facilitate the selection of interacting antibody antigen pairs from a large single chain antibody (scFv) library in vivo. The system is constructed with a m...A modified selectively infective phage (SIP) is developed to facilitate the selection of interacting antibody antigen pairs from a large single chain antibody (scFv) library in vivo. The system is constructed with a modified helper phage M13KO7 and phagemid pCANTAB 5 E. The antigen fused to the C terminal of N1 N2 domain and the scFv to the N terminal of CT domain of the gIIIp of filamentous phage are encoded on the phage and phagemid vectors respectively. The phages produced by co transformants restore infectivity via interaction between antigen and antibody fusions in the cell periplasm. In a model system, the scFv fragment of the anti hemagglutinin 17/9 antibody and its corresponding antigen are detected in the presence of a 10 5 fold excess of a non interacting control pairs, which demonstrates this system to be very sensitive and facile to screen a large single chain antibody library.展开更多
Test points selection for integer-coded fault wise table is a discrete optimization problem. On one hand, traditional exhaustive search method is computationally expensive. On the other hand, the space complexity of t...Test points selection for integer-coded fault wise table is a discrete optimization problem. On one hand, traditional exhaustive search method is computationally expensive. On the other hand, the space complexity of traditional exhaustive is low. A tradeoff method between the high time complexity and low space complexity is proposed. At first, a new fault-pair table is constructed based on the integer-coded fault wise table. The fault-pair table consists of two columns： one column represents fault pair and the other represents test points set that can distinguish the corresponding faults. Then, the rows are arranged in ascending order according to the cardinality of corresponding test points set. Thirdly, test points in the top rows are selected one by one until all fault pair are isolated. During the test points selection process, the rows that contain selected test points are deleted and then the dimension of fault-pair table decreases gradually. The proposed test points selection algorithm is illustrated and tested using an integercoded fault wise table derived from a real analog circuit. Computational results suggest show policies are better than the exhaustive strategy.展开更多
In order to improve the reliability of the mechanical movement of the rotary electronic dobby, the kinematics analysis of the heald selection mechanism is carried out and the simulation is carried out with Matlab. Fir...In order to improve the reliability of the mechanical movement of the rotary electronic dobby, the kinematics analysis of the heald selection mechanism is carried out and the simulation is carried out with Matlab. Firstly, the operation mechanism of the heald selection mechanism is analyzed in detail. The conjugate cam is mapped. The cam profile curve is fitted with cubic spline interpolation. Secondly, based on the overall analysis method and the complex vector method, the kinematics analysis of the key components after the high pair low generation is performed, and the angular displacement and angular velocity of each component are calculated with the rotation of the active cam. Finally, the movement curve diagram is drawn with Matlab, which lays the foundation for the dynamic analysis and in-depth study of the selection mechanism in the future.展开更多
Molecularly imprinted polymers (MIPs) have great potential as adsorbents for selective adsorption and separation of nucleoside compounds,but effectively enhancing the affinity of recognition sites by adjusting the for...Molecularly imprinted polymers (MIPs) have great potential as adsorbents for selective adsorption and separation of nucleoside compounds,but effectively enhancing the affinity of recognition sites by adjusting the forces between template molecules and functional monomers remains an important challenge.In this work,a surface imprinting strategy was used to construct bowl-shaped molecularly imprinted composite sorbents (BHPN@MIPs) based on polydopamine (PDA) particles and have achieved selective separation and purification of 2'-deoxyadenosine (dA).Where by the base complementary pairing interaction of the combined template molecule d A and the pyrimidine functional monomer can enhance the preassembly force,and the hydrophilic bowl-shaped PDA can provide a larger storage space contact efficiency of d A in the test solution,causing the site utilization much higher and improving the kinetic adsorption performance.The equilibrium adsorption time and maximum adsorption capacity of60 min and 328.45μmol·g^(-1)were observed by static adsorption experiments,and the selectivity experimental results showed an imprinting factor IF of 1.30.After four adsorption–desorption cycles,the initial adsorption equilibrium adsorption capacity of BHPN@MIPs still retained 91.14%.By evaluating the selective adsorption of d A in spiked human serum solutions,BHPN@MIPs can be used to selectively enrich and analyze target d A in complex biological samples.展开更多
We propose and experimentally demonstrate compact on-chip 1×2 wavelength selective switches(WSSs) based on silicon microring resonators(MRRs) with nested pairs of subrings(NPSs). Owing to the resonance splitting ...We propose and experimentally demonstrate compact on-chip 1×2 wavelength selective switches(WSSs) based on silicon microring resonators(MRRs) with nested pairs of subrings(NPSs). Owing to the resonance splitting induced by the inner NPSs, the proposed devices are capable of performing selective channel routing at certain resonance wavelengths of the outer MRRs. System demonstration of dynamic channel routing using fabricated devices with one and two NPSs is carried out for 10 Gb∕s non-return-to-zero signal. The experimental results verify the effectiveness of the fabricated devices as compact on-chip WSSs.展开更多
利用Wi-Fi信号中信道状态信息(Channel State Information,CSI)的变化特征可实现被动行为检测.通过预选择出CSI数据中性能优良的子载波和对环境区分度更好的MIMO天线对,实现对数据的深度预处理,以及在提取到幅值和相位差特征后,经过小...利用Wi-Fi信号中信道状态信息(Channel State Information,CSI)的变化特征可实现被动行为检测.通过预选择出CSI数据中性能优良的子载波和对环境区分度更好的MIMO天线对,实现对数据的深度预处理,以及在提取到幅值和相位差特征后,经过小波变换得到更细粒度特征的数据后处理算法,提高行为的识别率.实验结果表明,该算法在150组测试数据集上的分类准确率高达97.1%,比在同等条件下未经过预处理和后处理算法的分类准确率高约6.6%.展开更多
对于多输入多输出系统,在控制系统设计时首先要对被控变量和操纵变量进行控制结构选择.Bristol提出的相关增益矩阵(Relative gain array,RGA)法,以及学者们后来提出的各种改进方法,都只适用于稳定系统.本文针对不稳定系统,基于多变量广...对于多输入多输出系统,在控制系统设计时首先要对被控变量和操纵变量进行控制结构选择.Bristol提出的相关增益矩阵(Relative gain array,RGA)法,以及学者们后来提出的各种改进方法,都只适用于稳定系统.本文针对不稳定系统,基于多变量广义预测控制(Generalized predictive control,GPC)的闭环控制律提出了一种控制结构的变量匹配准则.通过对预测时域、控制时域等各个参数的优化选择,使系统闭环稳定;由闭环控制律得到被控变量期望值与操纵变量的相关性矩阵,以此得出控制结构的变量配对方案.通过实例研究表明,对于开环不稳定系统,该方法可以得出正确的变量配对结果.展开更多
文摘Selecting the optimal one from similar schemes is a paramount work in equipment design.In consideration of similarity of schemes and repetition of characteristic indices,the theory of set pair analysis(SPA)is proposed,and then an optimal selection model is established.In order to improve the accuracy and flexibility,the model is modified by the contribution degree.At last,this model has been validated by an example,and the result demonstrates the method is feasible and valuable for practical usage.
文摘A modified selectively infective phage (SIP) is developed to facilitate the selection of interacting antibody antigen pairs from a large single chain antibody (scFv) library in vivo. The system is constructed with a modified helper phage M13KO7 and phagemid pCANTAB 5 E. The antigen fused to the C terminal of N1 N2 domain and the scFv to the N terminal of CT domain of the gIIIp of filamentous phage are encoded on the phage and phagemid vectors respectively. The phages produced by co transformants restore infectivity via interaction between antigen and antibody fusions in the cell periplasm. In a model system, the scFv fragment of the anti hemagglutinin 17/9 antibody and its corresponding antigen are detected in the presence of a 10 5 fold excess of a non interacting control pairs, which demonstrates this system to be very sensitive and facile to screen a large single chain antibody library.
基金supported by National Natural Science Foundation of China under Grant No.60934002General Armament Department under Grant No.51317040102
文摘Test points selection for integer-coded fault wise table is a discrete optimization problem. On one hand, traditional exhaustive search method is computationally expensive. On the other hand, the space complexity of traditional exhaustive is low. A tradeoff method between the high time complexity and low space complexity is proposed. At first, a new fault-pair table is constructed based on the integer-coded fault wise table. The fault-pair table consists of two columns： one column represents fault pair and the other represents test points set that can distinguish the corresponding faults. Then, the rows are arranged in ascending order according to the cardinality of corresponding test points set. Thirdly, test points in the top rows are selected one by one until all fault pair are isolated. During the test points selection process, the rows that contain selected test points are deleted and then the dimension of fault-pair table decreases gradually. The proposed test points selection algorithm is illustrated and tested using an integercoded fault wise table derived from a real analog circuit. Computational results suggest show policies are better than the exhaustive strategy.
文摘In order to improve the reliability of the mechanical movement of the rotary electronic dobby, the kinematics analysis of the heald selection mechanism is carried out and the simulation is carried out with Matlab. Firstly, the operation mechanism of the heald selection mechanism is analyzed in detail. The conjugate cam is mapped. The cam profile curve is fitted with cubic spline interpolation. Secondly, based on the overall analysis method and the complex vector method, the kinematics analysis of the key components after the high pair low generation is performed, and the angular displacement and angular velocity of each component are calculated with the rotation of the active cam. Finally, the movement curve diagram is drawn with Matlab, which lays the foundation for the dynamic analysis and in-depth study of the selection mechanism in the future.
基金financially supported by the National Natural Science Foundation of China (22078132 and 22108103)Open Funding Project of the National Key Laboratory of Biochemical Engineering (2021KF-02)+3 种基金China Postdoctoral Science Foundation (2021M691301)Jiangsu Agricultural Independent Innovation Fund Project (CX(21)3079)Graduate Research Innovation Program of Jiangsu Province (KYCX20-3040)China Postdoctoral Science Foundation (2021M691301)。
文摘Molecularly imprinted polymers (MIPs) have great potential as adsorbents for selective adsorption and separation of nucleoside compounds,but effectively enhancing the affinity of recognition sites by adjusting the forces between template molecules and functional monomers remains an important challenge.In this work,a surface imprinting strategy was used to construct bowl-shaped molecularly imprinted composite sorbents (BHPN@MIPs) based on polydopamine (PDA) particles and have achieved selective separation and purification of 2'-deoxyadenosine (dA).Where by the base complementary pairing interaction of the combined template molecule d A and the pyrimidine functional monomer can enhance the preassembly force,and the hydrophilic bowl-shaped PDA can provide a larger storage space contact efficiency of d A in the test solution,causing the site utilization much higher and improving the kinetic adsorption performance.The equilibrium adsorption time and maximum adsorption capacity of60 min and 328.45μmol·g^(-1)were observed by static adsorption experiments,and the selectivity experimental results showed an imprinting factor IF of 1.30.After four adsorption–desorption cycles,the initial adsorption equilibrium adsorption capacity of BHPN@MIPs still retained 91.14%.By evaluating the selective adsorption of d A in spiked human serum solutions,BHPN@MIPs can be used to selectively enrich and analyze target d A in complex biological samples.
基金supported in part by the National Natural Science Foundation of China under Grant 61125504/61235007in part by the 863 High-Tech Program under Grant 2013AA013402
文摘We propose and experimentally demonstrate compact on-chip 1×2 wavelength selective switches(WSSs) based on silicon microring resonators(MRRs) with nested pairs of subrings(NPSs). Owing to the resonance splitting induced by the inner NPSs, the proposed devices are capable of performing selective channel routing at certain resonance wavelengths of the outer MRRs. System demonstration of dynamic channel routing using fabricated devices with one and two NPSs is carried out for 10 Gb∕s non-return-to-zero signal. The experimental results verify the effectiveness of the fabricated devices as compact on-chip WSSs.
文摘利用Wi-Fi信号中信道状态信息(Channel State Information,CSI)的变化特征可实现被动行为检测.通过预选择出CSI数据中性能优良的子载波和对环境区分度更好的MIMO天线对,实现对数据的深度预处理,以及在提取到幅值和相位差特征后,经过小波变换得到更细粒度特征的数据后处理算法,提高行为的识别率.实验结果表明,该算法在150组测试数据集上的分类准确率高达97.1%,比在同等条件下未经过预处理和后处理算法的分类准确率高约6.6%.
文摘对于多输入多输出系统,在控制系统设计时首先要对被控变量和操纵变量进行控制结构选择.Bristol提出的相关增益矩阵(Relative gain array,RGA)法,以及学者们后来提出的各种改进方法,都只适用于稳定系统.本文针对不稳定系统,基于多变量广义预测控制(Generalized predictive control,GPC)的闭环控制律提出了一种控制结构的变量匹配准则.通过对预测时域、控制时域等各个参数的优化选择,使系统闭环稳定;由闭环控制律得到被控变量期望值与操纵变量的相关性矩阵,以此得出控制结构的变量配对方案.通过实例研究表明,对于开环不稳定系统,该方法可以得出正确的变量配对结果.
