Cloud data centers face the largest energy consumption.In order to save energy consumption in cloud data centers,cloud service providers adopt a virtual machine migration strategy.In this paper,we propose an efficient...Cloud data centers face the largest energy consumption.In order to save energy consumption in cloud data centers,cloud service providers adopt a virtual machine migration strategy.In this paper,we propose an efficient virtual machine placement strategy(VMP-SI)based on virtual machine selection and integration.Our proposed VMP-SI strategy divides the migration process into three phases:physical host state detection,virtual machine selection and virtual machine placement.The local regression robust(LRR)algorithm and minimum migration time(MMT)policy are individual used in the first and section phase,respectively.Then we design a virtual machine migration strategy that integrates the process of virtual machine selection and placement,which can ensure a satisfactory utilization efficiency of the hardware resources of the active physical host.Experimental results show that our proposed method is better than the approach in Cloudsim under various performance metrics.展开更多
Near infrared spectroscopy (NIR) is now probably the most popular process analytical technology (PAT) for pharmaceutical and some other industries. However, unlike mid-IR, NIR is known to have difficulties in moni...Near infrared spectroscopy (NIR) is now probably the most popular process analytical technology (PAT) for pharmaceutical and some other industries. However, unlike mid-IR, NIR is known to have difficulties in monitoring crystallization or precipitation processes because the existence of solids could cause distortion of the spectra. This phenomenon, seen as unfavorable previously, is however an indication that NIR spectra contain rich information about both solids and liquids, giving the possibility of using the same instrument for multiple property characterization. In this study, transflectance NIR calibration data was obtained using solutions and slurries of varied solution concentration, particle size, solid concentration and temperature. The data was used to build calibration models for prediction of the multiple properties of both phases. Predictive models were developed for this challenging application using an approach that combines genetic algorithm (GA) and support vector machine (SVM). GA is used for wavelength selection and SVM for mode building. The new GA-SVM approach is shown to outperform other methods including GA-PLS (partial least squares) and traditional SVM. NIR is thus successfully applied to monitoring seeded and unseeded cooling crystallization processes of L-glutamic acid.展开更多
Essential proteins are vital to the survival of a cell. There are various features related to the essentiality of proteins, such as biological and topological features. Many computational methods have been developed t...Essential proteins are vital to the survival of a cell. There are various features related to the essentiality of proteins, such as biological and topological features. Many computational methods have been developed to identify essential proteins by using these features. However, it is still a big challenge to design an effective method that is able to select suitable features and integrate them to predict essential proteins. In this work, we first collect 26 features, and use SVM-RFE to select some of them to create a feature space for predicting essential proteins, and then remove the features that share the biological meaning with other features in the feature space according to their Pearson Correlation Coefficients(PCC). The experiments are carried out on S. cerevisiae data. Six features are determined as the best subset of features. To assess the prediction performance of our method, we further compare it with some machine learning methods, such as SVM, Naive Bayes, Bayes Network, and NBTree when inputting the different number of features. The results show that those methods using the 6 features outperform that using other features, which confirms the effectiveness of our feature selection method for essential protein prediction.展开更多
文摘Cloud data centers face the largest energy consumption.In order to save energy consumption in cloud data centers,cloud service providers adopt a virtual machine migration strategy.In this paper,we propose an efficient virtual machine placement strategy(VMP-SI)based on virtual machine selection and integration.Our proposed VMP-SI strategy divides the migration process into three phases:physical host state detection,virtual machine selection and virtual machine placement.The local regression robust(LRR)algorithm and minimum migration time(MMT)policy are individual used in the first and section phase,respectively.Then we design a virtual machine migration strategy that integrates the process of virtual machine selection and placement,which can ensure a satisfactory utilization efficiency of the hardware resources of the active physical host.Experimental results show that our proposed method is better than the approach in Cloudsim under various performance metrics.
基金UK Engineering and Physical Sciences Research Council for funding the research (EPSRCGrant Reference: EP/C001788/1)
文摘Near infrared spectroscopy (NIR) is now probably the most popular process analytical technology (PAT) for pharmaceutical and some other industries. However, unlike mid-IR, NIR is known to have difficulties in monitoring crystallization or precipitation processes because the existence of solids could cause distortion of the spectra. This phenomenon, seen as unfavorable previously, is however an indication that NIR spectra contain rich information about both solids and liquids, giving the possibility of using the same instrument for multiple property characterization. In this study, transflectance NIR calibration data was obtained using solutions and slurries of varied solution concentration, particle size, solid concentration and temperature. The data was used to build calibration models for prediction of the multiple properties of both phases. Predictive models were developed for this challenging application using an approach that combines genetic algorithm (GA) and support vector machine (SVM). GA is used for wavelength selection and SVM for mode building. The new GA-SVM approach is shown to outperform other methods including GA-PLS (partial least squares) and traditional SVM. NIR is thus successfully applied to monitoring seeded and unseeded cooling crystallization processes of L-glutamic acid.
基金supported by the National Natural Science Foundation of China(Nos.61232001,61502166,61502214,61379108,and 61370024)Scientific Research Fund of Hunan Provincial Education Department(Nos.15CY007 and 10A076)
文摘Essential proteins are vital to the survival of a cell. There are various features related to the essentiality of proteins, such as biological and topological features. Many computational methods have been developed to identify essential proteins by using these features. However, it is still a big challenge to design an effective method that is able to select suitable features and integrate them to predict essential proteins. In this work, we first collect 26 features, and use SVM-RFE to select some of them to create a feature space for predicting essential proteins, and then remove the features that share the biological meaning with other features in the feature space according to their Pearson Correlation Coefficients(PCC). The experiments are carried out on S. cerevisiae data. Six features are determined as the best subset of features. To assess the prediction performance of our method, we further compare it with some machine learning methods, such as SVM, Naive Bayes, Bayes Network, and NBTree when inputting the different number of features. The results show that those methods using the 6 features outperform that using other features, which confirms the effectiveness of our feature selection method for essential protein prediction.