Purpose research on nursing sensitive indicators in tumor Patients application effect in immune-related skin toxicity management. Method select our hospital April to June, 202360 cases patients with immune therapy set...Purpose research on nursing sensitive indicators in tumor Patients application effect in immune-related skin toxicity management. Method select our hospital April to June, 202360 cases patients with immune therapy settings as the control group. August-October, 2023 60 cases the patients treated with immune therapy were the experimental group. The control group adopted regular nursing methods, while the experimental group sensitive Indicators, evidence-based give preventive care. The social situation, psychological state, physical function, quality of life score, incidence of skin toxicity caused by immune checkpoint inhibitors, moderate and above of the two groups of patients were compared. Incidence of skin toxicity. Result: experience group SAS score, SDS score higher than the control group, the difference was statistically significant (P < 0.05);The incidence of skin toxic reactions caused by immune checkpoint inhibitors and the incidence of moderate and above skin toxic reactions in the experimental group are lower than those in the control group, and the difference is statistically significant (P < 0.05). Conclusion: sensitive indicator guidance evidence-based preventive care can reduce the degree of immune-related skin toxicity, improve the psychological state and quality of life of tumor patients treated with immune therapy and reduce the incidence of adverse reactions, improve nursing quality and patient satisfaction.展开更多
GM(1,1)models have been widely used in various fields due to their high performance in time series prediction.However,some hypotheses of the existing GM(1,1)model family may reduce their prediction performance in some...GM(1,1)models have been widely used in various fields due to their high performance in time series prediction.However,some hypotheses of the existing GM(1,1)model family may reduce their prediction performance in some cases.To solve this problem,this paper proposes a self-adaptive GM(1,1)model,termed as SAGM(1,1)model,which aims to solve the defects of the existing GM(1,1)model family by deleting their modeling hypothesis.Moreover,a novel multi-parameter simultaneous optimization scheme based on firefly algorithm is proposed,the proposed multi-parameter optimization scheme adopts machine learning ideas,takes all adjustable parameters of SAGM(1,1)model as input variables,and trains it with firefly algorithm.And Sobol’sensitivity indices are applied to study global sensitivity of SAGM(1,1)model parameters,which provides an important reference for model parameter calibration.Finally,forecasting capability of SAGM(1,1)model is illustrated by Anhui electricity consumption dataset.Results show that prediction accuracy of SAGM(1,1)model is significantly better than other models,and it is shown that the proposed approach enhances the prediction performance of GM(1,1)model significantly.展开更多
文摘Purpose research on nursing sensitive indicators in tumor Patients application effect in immune-related skin toxicity management. Method select our hospital April to June, 202360 cases patients with immune therapy settings as the control group. August-October, 2023 60 cases the patients treated with immune therapy were the experimental group. The control group adopted regular nursing methods, while the experimental group sensitive Indicators, evidence-based give preventive care. The social situation, psychological state, physical function, quality of life score, incidence of skin toxicity caused by immune checkpoint inhibitors, moderate and above of the two groups of patients were compared. Incidence of skin toxicity. Result: experience group SAS score, SDS score higher than the control group, the difference was statistically significant (P < 0.05);The incidence of skin toxic reactions caused by immune checkpoint inhibitors and the incidence of moderate and above skin toxic reactions in the experimental group are lower than those in the control group, and the difference is statistically significant (P < 0.05). Conclusion: sensitive indicator guidance evidence-based preventive care can reduce the degree of immune-related skin toxicity, improve the psychological state and quality of life of tumor patients treated with immune therapy and reduce the incidence of adverse reactions, improve nursing quality and patient satisfaction.
基金supported by the National Natural Science Foundation of China(72171116,71671090)the Fundamental Research Funds for the Central Universities(NP2020022)+1 种基金the Key Research Projects of Humanities and Social Sciences in Anhui Education Department(SK2021A1018)Qinglan Project for Excellent Youth or Middlea ged Academic Leaders in Jiangsu Province,China.
文摘GM(1,1)models have been widely used in various fields due to their high performance in time series prediction.However,some hypotheses of the existing GM(1,1)model family may reduce their prediction performance in some cases.To solve this problem,this paper proposes a self-adaptive GM(1,1)model,termed as SAGM(1,1)model,which aims to solve the defects of the existing GM(1,1)model family by deleting their modeling hypothesis.Moreover,a novel multi-parameter simultaneous optimization scheme based on firefly algorithm is proposed,the proposed multi-parameter optimization scheme adopts machine learning ideas,takes all adjustable parameters of SAGM(1,1)model as input variables,and trains it with firefly algorithm.And Sobol’sensitivity indices are applied to study global sensitivity of SAGM(1,1)model parameters,which provides an important reference for model parameter calibration.Finally,forecasting capability of SAGM(1,1)model is illustrated by Anhui electricity consumption dataset.Results show that prediction accuracy of SAGM(1,1)model is significantly better than other models,and it is shown that the proposed approach enhances the prediction performance of GM(1,1)model significantly.
