Interference-Free Pilot Design and Channel Estimation Using ZCZ Sequences for MIMO-OFDM-Based C-V2X Communications

Cellular vehicle-to-everything(C-V2X) communications is regarded as a promising and feasible solution for 5G-enabled vehicular communications and networking. In this paper, we investigate the pilot design and channel estimation problem in MIMO-OFDM-based C-V2X systems with severe co-channel interference due to spectrum reusing among different V2X communication links. By using zero-correlation zone(ZCZ) sequences, we provide an interference-free pilot design scheme and a corresponding time-domain(TD) correlation-based channel estimation(TD-CCE) method. We employ the ZCZ sequences from the same family set to be designed as the TD pilot symbols and guarantee the pilot sequeneces for neighboring V2X communication links are code-division multiplexing(CDM). The co-channel pilot interference of the deisgned pilot symbols can be effectively eliminated by exploiting the provided TD-CCE method. Simulation results indicate that the accuracy of channel estimation can be effectively improved by the proposed scheme, whose performance is close to that of the non-interference situation.

Design of control sequence of pulses for the population transfer of high dimensional spin 1/2 quantum systems

On the basis of the relationship between the Hamiltonian of spin 1/2 quantum system under control and the energy level structure and transitions, a radio frequency pulse sequence is designed using intuitive and half counter-intuitive sequences of pulse to transfer the population of the 3-qubit system coherently. The effectiveness of the designed control sequence is verified through the system simulation experiment of the evolution of state. In principle, the design method of the control pulse sequence proposed can be generalized to use in the quantum systems of higher dimension.

A novel deep generative model for mRNA vaccine development: Designing 5′ UTRs with N1-methyl-pseudouridine modification

Efficient translation mediated by the 5'untranslated region(5'UTR)is essential for the robust efficacy of mRNA vaccines.However,the N1-methyl-pseudouridine(m1)modification of mRNA can impact the translation efficiency of the 5'UTR.We discovered that the optimal 5'UTR for m1y-modified mRNA(m1y-5'UTR)differs significantly from its unmodified counterpart,high-lighting the need for a specialized tool for designing mly-5'UTRs rather than directly utilizing high-expression endogenous gene 5'UTRs.In response,we developed a novel machine learning-based tool,Smart5UTR,which employs a deep generative model to identify superior m1y-5'UTRs in silico.The tailored loss function and network architecture enable Smart5UTR to overcome limitations inherent in existing models.As a result,Smart5UTR can successfully design superior 5'UTRs,greatly benefiting mRNA vaccine development.Notably,Smart5UTR-designed superior 5'UTRs significantly enhanced antibody titers induced by COVID-19 mRNA vaccines against the Delta and Omicron variants of SARS-CoV-2,surpassing the performance of vaccines using high-expression endogenous gene 5'UTRs.

Constructions for almost perfect binary sequence pairs with even length

The concept of the binary sequence pair is generalized from a single binary sequence. Binary sequence pairs are applied in many fields of radar, sonar or communication systems, in which signals with optimal periodic correlation are required. Several types of almost perfect binary sequence pairs of length T = 2q are constructed, where q is an odd number. These almost perfect binary sequence pairs are based on binary ideal sequence or binary ideal two-level correlation sequence pairs by using Chinese remainder theorem. For these almost perfect binary sequence pairs with good balanced property, their corresponding divisible difference set pairs(DDSPs) are also derived.

On a general class of quadratic hopping sequences

Based upon quadratic polynomials over the finite field, a new class of frequency hopping sequences with large family size suitable for applications in time/frequency hopping CDMA systems, multi-user radar and sonar systems is proposed and investigated. It is shown that the new time/frequency hopping sequences have at most one hit in their autocorrelation functions and at most two hits in their crosscorrelation functions except for a special case, and their family size is much larger than the conventional quadratic hopping sequences. The percentage of full collisions for the new quadratic hopping sequences is discussed. In addition, the average number of hits for the new quadratic hopping sequences, quadratic congruence sequences, extended quadratic congruence sequences and the general linear hopping sequences are also derived.