Osteoporosis,a prevalent systemic degenerative disease,poses significant challenges to China’s national health,particularly due to complications such as fractures.Therapeutic interventions for osteoporosis primarily ...Osteoporosis,a prevalent systemic degenerative disease,poses significant challenges to China’s national health,particularly due to complications such as fractures.Therapeutic interventions for osteoporosis primarily involve bone resorption inhibitors(antiresorptive)and bone formation promoters(anabolic).Numerous studies underscore the importance of sequential and combination treatments using diverse drug types.Such approaches have shown considerable efficacy in increasing bone mineral density,reducing fracture risk,and preventing the progression of osteoporosis.This article aimed to consolidate various sequential treatment schemes,offering valuable insights for clinicians in their practice.展开更多
This paper presents a sequential approach with matrix framework for solving various kinds of economic dispatch problems. The objective of the economic dispatch problems of electrical power generation is to schedule th...This paper presents a sequential approach with matrix framework for solving various kinds of economic dispatch problems. The objective of the economic dispatch problems of electrical power generation is to schedule the committed generating units output so as to meet the required load demand while satisfying the system equality and inequality constraints. This is a maiden approach developed to obtain the optimal dispatches of generating units for all possible load demands of power system in a single execution. The feasibility of the proposed method is demonstrated by solving economic load dispatch problem, combined economic and emission dispatch problem, multiarea economic dispatch problem and economic dispatch problem with multiple fuel options. The proposed methodology is tested with different scale of power systems. The generating unit operational constraints are also considered. The simulation results obtained by proposed methodology for various economic dispatch problems are compared with previous literatures in terms of solution quality. Numerical simulation results indicate an improvement in total cost saving and hence the superiority of the proposed method is also revealed for economic dispatch problems.展开更多
某电厂安萨尔多AE94.3A燃气-蒸汽联合循环调峰机组,在投入商业运行初期,运行人员在机组启停过程中有过多次误操作,导致机组跳闸。在原有集散控制系统(DCS)的基础上进行了自动启停(automatic procedure startup and shutdown,APS)技术升...某电厂安萨尔多AE94.3A燃气-蒸汽联合循环调峰机组,在投入商业运行初期,运行人员在机组启停过程中有过多次误操作,导致机组跳闸。在原有集散控制系统(DCS)的基础上进行了自动启停(automatic procedure startup and shutdown,APS)技术升级改造,从而降低了运行人员的工作强度,减少误操作,对机组长期的安全稳定运行有重大意义。本文围绕某电厂安萨尔多AE94.3A联合循环机组自动启停技术项目的实施,介绍了自动启停技术整体设计框架,并对各功能断点进行了分层解析,最终对项目碰到的难点进行分析,提出了解决方案。展开更多
Background The prognostic power of n-terminal pro-brain natriuretic peptide （NT-proBNP） in sepsis is disputable and unstable among different models. We attempt to evaluate the prognostic potential of NT-proBNP in co...Background The prognostic power of n-terminal pro-brain natriuretic peptide （NT-proBNP） in sepsis is disputable and unstable among different models. We attempt to evaluate the prognostic potential of NT-proBNP in combination with the sequential organ failure assessment （SOFA） score in sepsis. Methods In this retrospective study, 100 consecutive sepsis patients were enrolled. Clinical data such as admission SOFA, the Acute Physiologic and Chronic Health Evaluation score, shock prevalence, use of lung protective ventilation, vasopressors, and glucocorticoids were recorded. Additionally, serum creatinine （Scrl and Scr3） and NT-proBNP （NT-proBNP1 and NT-proBNP3） were assayed and evaluated at admission and on day 3 respectively. Results ANT-proBNP （NT-proBNP3 minus NT-proBNP1） （P 〈0.001, Hazard ratio （HR）=1.245, 95% confidence interval （CI）, 1.137-1.362） and admission SOFA （P 〈0.001, HR=1.197, 95% CI, 1.106-1.295） were independently related to in-hospital mortality. Their combination was a more robust predictor for in-hospital mortality than either of them individually. Patients with high ANT-proBNP and SOFA had the poorest prognosis. Conclusions In our study, both ANT-proBNP and SOFA were independent predictors of septic patients＇ prognosis. Moreover, the combination of ,~NT-proBNP and admission SOFA provided a novel strategy that contained information regarding both the response to treatment and sepsis severity.展开更多
OBJECTIVE:To evaluate the clinical efficacy of nourishing Yin and tonifying Yang sequential therapy(NYTYST)in combination with the Western Medicine Climen in treating diminished ovarian reserve(DOR).METHODS:From Septe...OBJECTIVE:To evaluate the clinical efficacy of nourishing Yin and tonifying Yang sequential therapy(NYTYST)in combination with the Western Medicine Climen in treating diminished ovarian reserve(DOR).METHODS:From September 2014 to September2016,46 patients with DOR who received NYTYST and Climen(treatment group)and 51 patients who received Climen only(control group)at the Jiangsu Provincial Traditional Chinese Medicine Hospital(Nanjing,China)were retrospectively reviewed.Before and at 3 months after treatment,serum levels of follicle-stimulating hormone(FSH),FSH/luteinizing hormone(LH),estradiol(E2),and anti-Mullerian hormone(AMH),the antral follicle count(AFC),stromal peak systolic velocity(PSV),symptom scores,and the clinical effectiveness rate were measured and compared between the two groups.RESULTS:After treatment,serum levels of FSH,FSH/LH and E2,and symptom scores were significantly decreased compared with before treatment(all P<0.05)in the two groups.AMH levels,AFC,and PSV were significantly increased after treatment compared with before treatment in both groups(all P<0.05).Serum levels of FSH,FSH/LH,and E2 after treatment were significantly lower in the treatment group than in the control group(all P<0.05).However,AMH levels and the AFC were significantly higher after treatment in the treatment group than in the control group(both P<0.05).The clinical effectiveness rate was significantly higher in the treatment group than in the control group(87%vs 68.6%,P<0.05).CONCLUSION:NYTYST combined with Climen may be more effective in treating DOR than Climen alone.展开更多
In this paper it is shown that cyclostationary spectrum sensing for Cognitive Radio networks, applying multiple cyclic frequencies for single user detection can be interpreted (with some assumptions) in terms of optim...In this paper it is shown that cyclostationary spectrum sensing for Cognitive Radio networks, applying multiple cyclic frequencies for single user detection can be interpreted (with some assumptions) in terms of optimal incoherent diversity addition for “virtual diversity branches” or SIMO radar. This approach allows proposing, by analogy to diversity combining, suboptimal algorithms which can provide near optimal characteristics for the Neyman-Pearson Test (NPT) for single user detection. The analysis is based on the Generalized Gaussian (Klovsky-Middleton) Channel Model, which allows obtaining the NPT noise immunity characteristics: probability of misdetection error (PM) and probability of false alarm (Pfa) or Receiver Operational Characteristics (ROC) in the most general way. Some quasi-optimum algorithms such as energetic receiver and selection addition algorithm are analyzed and their comparison with the noise immunity properties (ROC) of the optimum approach is provided as well. Finally, the diversity combining approach is applied for the collaborative spectrum sensing and censoring. It is shown how the diversity addition principles are applied for distributed detection algorithms, called hereafter as SIMO radar or distributed SIMO radar, implementing Majority Addition (MA) approach and Weighted Majority Addition (WMA) principle.展开更多
INTRODUCTIONLeft ventricular aneurysm and ischemic mitral regurgitation are two of most common complications of acute myocardial infarction （AMI）. Combination of both these two fatal complications is not rare and th...INTRODUCTIONLeft ventricular aneurysm and ischemic mitral regurgitation are two of most common complications of acute myocardial infarction （AMI）. Combination of both these two fatal complications is not rare and the management of these complicated cases is always a challenge to cardiac surgeon because of its relatively high mortality. We reported a rare case of AMI in which a singlestage correction of mitral valve replacement with preservation of mitral apparatus, sequential left internal thoracic artery （ITA） grafting and Cooley＇s technique.展开更多
基金The Undergraduate Research Innovation Program of Capital Medical University(Grant No.XSKY2021387).
文摘Osteoporosis,a prevalent systemic degenerative disease,poses significant challenges to China’s national health,particularly due to complications such as fractures.Therapeutic interventions for osteoporosis primarily involve bone resorption inhibitors(antiresorptive)and bone formation promoters(anabolic).Numerous studies underscore the importance of sequential and combination treatments using diverse drug types.Such approaches have shown considerable efficacy in increasing bone mineral density,reducing fracture risk,and preventing the progression of osteoporosis.This article aimed to consolidate various sequential treatment schemes,offering valuable insights for clinicians in their practice.
文摘This paper presents a sequential approach with matrix framework for solving various kinds of economic dispatch problems. The objective of the economic dispatch problems of electrical power generation is to schedule the committed generating units output so as to meet the required load demand while satisfying the system equality and inequality constraints. This is a maiden approach developed to obtain the optimal dispatches of generating units for all possible load demands of power system in a single execution. The feasibility of the proposed method is demonstrated by solving economic load dispatch problem, combined economic and emission dispatch problem, multiarea economic dispatch problem and economic dispatch problem with multiple fuel options. The proposed methodology is tested with different scale of power systems. The generating unit operational constraints are also considered. The simulation results obtained by proposed methodology for various economic dispatch problems are compared with previous literatures in terms of solution quality. Numerical simulation results indicate an improvement in total cost saving and hence the superiority of the proposed method is also revealed for economic dispatch problems.
文摘某电厂安萨尔多AE94.3A燃气-蒸汽联合循环调峰机组,在投入商业运行初期,运行人员在机组启停过程中有过多次误操作,导致机组跳闸。在原有集散控制系统(DCS)的基础上进行了自动启停(automatic procedure startup and shutdown,APS)技术升级改造,从而降低了运行人员的工作强度,减少误操作,对机组长期的安全稳定运行有重大意义。本文围绕某电厂安萨尔多AE94.3A联合循环机组自动启停技术项目的实施,介绍了自动启停技术整体设计框架,并对各功能断点进行了分层解析,最终对项目碰到的难点进行分析,提出了解决方案。
文摘Background The prognostic power of n-terminal pro-brain natriuretic peptide （NT-proBNP） in sepsis is disputable and unstable among different models. We attempt to evaluate the prognostic potential of NT-proBNP in combination with the sequential organ failure assessment （SOFA） score in sepsis. Methods In this retrospective study, 100 consecutive sepsis patients were enrolled. Clinical data such as admission SOFA, the Acute Physiologic and Chronic Health Evaluation score, shock prevalence, use of lung protective ventilation, vasopressors, and glucocorticoids were recorded. Additionally, serum creatinine （Scrl and Scr3） and NT-proBNP （NT-proBNP1 and NT-proBNP3） were assayed and evaluated at admission and on day 3 respectively. Results ANT-proBNP （NT-proBNP3 minus NT-proBNP1） （P 〈0.001, Hazard ratio （HR）=1.245, 95% confidence interval （CI）, 1.137-1.362） and admission SOFA （P 〈0.001, HR=1.197, 95% CI, 1.106-1.295） were independently related to in-hospital mortality. Their combination was a more robust predictor for in-hospital mortality than either of them individually. Patients with high ANT-proBNP and SOFA had the poorest prognosis. Conclusions In our study, both ANT-proBNP and SOFA were independent predictors of septic patients＇ prognosis. Moreover, the combination of ,~NT-proBNP and admission SOFA provided a novel strategy that contained information regarding both the response to treatment and sepsis severity.
基金Supported by the Clinical Medical Science and Technology Special of Jiangsu Provincial Science and Technology Project(No.BL2013039).
文摘OBJECTIVE:To evaluate the clinical efficacy of nourishing Yin and tonifying Yang sequential therapy(NYTYST)in combination with the Western Medicine Climen in treating diminished ovarian reserve(DOR).METHODS:From September 2014 to September2016,46 patients with DOR who received NYTYST and Climen(treatment group)and 51 patients who received Climen only(control group)at the Jiangsu Provincial Traditional Chinese Medicine Hospital(Nanjing,China)were retrospectively reviewed.Before and at 3 months after treatment,serum levels of follicle-stimulating hormone(FSH),FSH/luteinizing hormone(LH),estradiol(E2),and anti-Mullerian hormone(AMH),the antral follicle count(AFC),stromal peak systolic velocity(PSV),symptom scores,and the clinical effectiveness rate were measured and compared between the two groups.RESULTS:After treatment,serum levels of FSH,FSH/LH and E2,and symptom scores were significantly decreased compared with before treatment(all P<0.05)in the two groups.AMH levels,AFC,and PSV were significantly increased after treatment compared with before treatment in both groups(all P<0.05).Serum levels of FSH,FSH/LH,and E2 after treatment were significantly lower in the treatment group than in the control group(all P<0.05).However,AMH levels and the AFC were significantly higher after treatment in the treatment group than in the control group(both P<0.05).The clinical effectiveness rate was significantly higher in the treatment group than in the control group(87%vs 68.6%,P<0.05).CONCLUSION:NYTYST combined with Climen may be more effective in treating DOR than Climen alone.
文摘In this paper it is shown that cyclostationary spectrum sensing for Cognitive Radio networks, applying multiple cyclic frequencies for single user detection can be interpreted (with some assumptions) in terms of optimal incoherent diversity addition for “virtual diversity branches” or SIMO radar. This approach allows proposing, by analogy to diversity combining, suboptimal algorithms which can provide near optimal characteristics for the Neyman-Pearson Test (NPT) for single user detection. The analysis is based on the Generalized Gaussian (Klovsky-Middleton) Channel Model, which allows obtaining the NPT noise immunity characteristics: probability of misdetection error (PM) and probability of false alarm (Pfa) or Receiver Operational Characteristics (ROC) in the most general way. Some quasi-optimum algorithms such as energetic receiver and selection addition algorithm are analyzed and their comparison with the noise immunity properties (ROC) of the optimum approach is provided as well. Finally, the diversity combining approach is applied for the collaborative spectrum sensing and censoring. It is shown how the diversity addition principles are applied for distributed detection algorithms, called hereafter as SIMO radar or distributed SIMO radar, implementing Majority Addition (MA) approach and Weighted Majority Addition (WMA) principle.
基金supported by grants National Dis-tinguished Youth Science Fund (No.30525020)
文摘INTRODUCTIONLeft ventricular aneurysm and ischemic mitral regurgitation are two of most common complications of acute myocardial infarction （AMI）. Combination of both these two fatal complications is not rare and the management of these complicated cases is always a challenge to cardiac surgeon because of its relatively high mortality. We reported a rare case of AMI in which a singlestage correction of mitral valve replacement with preservation of mitral apparatus, sequential left internal thoracic artery （ITA） grafting and Cooley＇s technique.
