Dyslipidemia the major cause of atherosclerosis are suggested to act synergistically with non-lipid risk factors to increase atherogenesis.Low-density lipoprotein cholesterol(LDL-C) is the main therapeutic target in t...Dyslipidemia the major cause of atherosclerosis are suggested to act synergistically with non-lipid risk factors to increase atherogenesis.Low-density lipoprotein cholesterol(LDL-C) is the main therapeutic target in the prevention of CVD.Increased triglycerides(TG) and decreased high-density lipoprotein(LDL-C) are considered to be a major risk factor for the development of insulin resistant and metabolic syndrome.Although the TG/ HDL-C ratio has been used in recent studies as a clinical indicator for insulin resistance,results were inconsistent. The TG/HDL-C ratio is also widely used to assess the lipid atherogenesis.How ever the utility of this rate for predicting coronary heart disease(CHD) risk is not clear.We encountered myocardial infarct patients with normal serum lipid concentration so this study was undertaken to evaluate the usefulness of these lipid ratios in predicting CHD risk in normolipidemic AMI patients and to compare the results with healthy subjects.The aim of the present study was to evaluate serum TC/HDL-C,TG/HDL-C and LDL-C/HDL-C in myocardial infarct subjects with normal lipid profile.To study this,lipid profile was determined in 165 normolipidemic acute myocardial infarction patients and 165 age/sex-matched controls.Total cholesterol,triglycerides,and HDL-cholesterol were analyzed enzymatically using kits obtained from Randox Laboratories Limited,Crumlin,UK. Plasma LDL-cholesterol was determined from the values of total cholesterol and HDL- cholesterol using the friedwalds formula.The values were expressed as means±standard deviation(SD) and data from patients and controls was compared using students t-test.The results and conclusion of the study were:Total cholesterol, TC:HDL-C ratio,triglycerides,LDL-cholesterol,LDL:HDL-C ratio were higher in MI patients(p【0. 001).HDL-C concentration was significantly lower in MI patients than controls(p【0.001).Higher ratio of TC/HDL-C,TG/HDL-C and LDL-C/HDL-C was observed in AMI patients compared to controls.展开更多
目的探讨分析不同年龄阶段抗苗勒氏管激素(anti-mullerian hormone,AMH)与三酰甘油(triglyceride,TG)、高密度脂蛋白胆固醇(high density liptein cholesterol,HDL-C)、低密度脂蛋白(low density lipoprotein,LDL)等心血管风险因子相关...目的探讨分析不同年龄阶段抗苗勒氏管激素(anti-mullerian hormone,AMH)与三酰甘油(triglyceride,TG)、高密度脂蛋白胆固醇(high density liptein cholesterol,HDL-C)、低密度脂蛋白(low density lipoprotein,LDL)等心血管风险因子相关性。方法将我院2018年12月—2019年12月门诊计划生育专科体检的100例育龄期女性作为研究对象,将其分为25~35岁女性作为A组,将36~45岁女性作为B组,对其血清抗苗勒氏管激素进行测定,分析与其TG、HDL-C、LDL-C等心血管风险评估指标之间的相关性。结果A组女性抗苗勒氏管激素水平与血清甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、血清总胆固醇(TC)之间正线相关性(P<0.05),与高密度脂蛋白胆固醇(HDL-C)之间无明显相关性(P>0.05)。B组女性的抗苗勒氏管激素水平与TG、HDL-C、LDL-C、TC等风险因子之间并无明显相关性(P>0.05)。结论针对各年龄阶段育龄期女性血清抗苗勒氏管激素水平测定,对早期心血管疾病发生及评估具有一定的临床参考价值。展开更多
Serum lipids were determined in 100 psoriatics and the results indicated (1) the incidences of hypercholesterolemia (9%) and hypertriglyceridemia (17%) in psoriatics were significantly higher than in controls; (2) the...Serum lipids were determined in 100 psoriatics and the results indicated (1) the incidences of hypercholesterolemia (9%) and hypertriglyceridemia (17%) in psoriatics were significantly higher than in controls; (2) the mean values of serum TC, LDL-C and TC/HDL-C in psoriatics were significantly higher as compared with normal healthy controls matched for sex and age; (3) serum TC, LDL-C and TG values were significantly higher in cases whose disease was progressive or whose lesions involved more than 20% of body surface area than in cases whose disease stationary or lesions less than 20%. As the incidences of hypertension and coronary heart disease were also significantly higher in psoriatics than in controls, the authors proposed that some integrated relationship would exist.展开更多
文摘Dyslipidemia the major cause of atherosclerosis are suggested to act synergistically with non-lipid risk factors to increase atherogenesis.Low-density lipoprotein cholesterol(LDL-C) is the main therapeutic target in the prevention of CVD.Increased triglycerides(TG) and decreased high-density lipoprotein(LDL-C) are considered to be a major risk factor for the development of insulin resistant and metabolic syndrome.Although the TG/ HDL-C ratio has been used in recent studies as a clinical indicator for insulin resistance,results were inconsistent. The TG/HDL-C ratio is also widely used to assess the lipid atherogenesis.How ever the utility of this rate for predicting coronary heart disease(CHD) risk is not clear.We encountered myocardial infarct patients with normal serum lipid concentration so this study was undertaken to evaluate the usefulness of these lipid ratios in predicting CHD risk in normolipidemic AMI patients and to compare the results with healthy subjects.The aim of the present study was to evaluate serum TC/HDL-C,TG/HDL-C and LDL-C/HDL-C in myocardial infarct subjects with normal lipid profile.To study this,lipid profile was determined in 165 normolipidemic acute myocardial infarction patients and 165 age/sex-matched controls.Total cholesterol,triglycerides,and HDL-cholesterol were analyzed enzymatically using kits obtained from Randox Laboratories Limited,Crumlin,UK. Plasma LDL-cholesterol was determined from the values of total cholesterol and HDL- cholesterol using the friedwalds formula.The values were expressed as means±standard deviation(SD) and data from patients and controls was compared using students t-test.The results and conclusion of the study were:Total cholesterol, TC:HDL-C ratio,triglycerides,LDL-cholesterol,LDL:HDL-C ratio were higher in MI patients(p【0. 001).HDL-C concentration was significantly lower in MI patients than controls(p【0.001).Higher ratio of TC/HDL-C,TG/HDL-C and LDL-C/HDL-C was observed in AMI patients compared to controls.
文摘目的探讨分析不同年龄阶段抗苗勒氏管激素(anti-mullerian hormone,AMH)与三酰甘油(triglyceride,TG)、高密度脂蛋白胆固醇(high density liptein cholesterol,HDL-C)、低密度脂蛋白(low density lipoprotein,LDL)等心血管风险因子相关性。方法将我院2018年12月—2019年12月门诊计划生育专科体检的100例育龄期女性作为研究对象,将其分为25~35岁女性作为A组,将36~45岁女性作为B组,对其血清抗苗勒氏管激素进行测定,分析与其TG、HDL-C、LDL-C等心血管风险评估指标之间的相关性。结果A组女性抗苗勒氏管激素水平与血清甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、血清总胆固醇(TC)之间正线相关性(P<0.05),与高密度脂蛋白胆固醇(HDL-C)之间无明显相关性(P>0.05)。B组女性的抗苗勒氏管激素水平与TG、HDL-C、LDL-C、TC等风险因子之间并无明显相关性(P>0.05)。结论针对各年龄阶段育龄期女性血清抗苗勒氏管激素水平测定,对早期心血管疾病发生及评估具有一定的临床参考价值。
文摘Serum lipids were determined in 100 psoriatics and the results indicated (1) the incidences of hypercholesterolemia (9%) and hypertriglyceridemia (17%) in psoriatics were significantly higher than in controls; (2) the mean values of serum TC, LDL-C and TC/HDL-C in psoriatics were significantly higher as compared with normal healthy controls matched for sex and age; (3) serum TC, LDL-C and TG values were significantly higher in cases whose disease was progressive or whose lesions involved more than 20% of body surface area than in cases whose disease stationary or lesions less than 20%. As the incidences of hypertension and coronary heart disease were also significantly higher in psoriatics than in controls, the authors proposed that some integrated relationship would exist.
