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EFFECT OF INHALED NANO-TiO_2 ON LUNG AND SERUM BIOCHEMICAL INDEXES OF MICE 被引量:2
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作者 何娉婷 陶杰 +2 位作者 张焱焱 汤育欣 王月勤 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2010年第4期338-344,共7页
The effect of inhaled nano-TiO2 on lung histology and serum biochemical indexes is evaluated in healthy and adult Kunming mice(eight in each group)after exposure to TiO2 aerosols(1 500 mg/m3)in a sealed chamber.An... The effect of inhaled nano-TiO2 on lung histology and serum biochemical indexes is evaluated in healthy and adult Kunming mice(eight in each group)after exposure to TiO2 aerosols(1 500 mg/m3)in a sealed chamber.Another eight mice are exposed to indoor air to be served as a control group.Lung tissue and blood are collected after euthanizing the animals.The results show that lactate dehydrogenase(LDH)activity increases in all experimental groups.Alanine aminotransferase(ALT)activity and blood urea nitrogen(BUN)levels are increased in the group exposed to TiO2 aerosols for 28 d,and creatinine(Cr)levels are increased in 14 d and 28 d samples(P0.05).No obvious changes are observed in other serum indexes.Lungs of mice exposed to 28 d exposure show significant but moderate increase in pulmonary inflammation,and many TiO2 particles are found in the interstitium of pulmonary alveoli. 展开更多
关键词 Titanium dioxide particle NANOMATERIAL pulmonary toxicity serum biochemical indexes INHALATION TOXICOLOGY
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Effects of Compound Herbal Medicine on Serum Biochemical Indexes and Egg Nutritional Quality in Laying Hens 被引量:3
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作者 ZHANG Li-juan WANG Zhi-xiang 《Animal Husbandry and Feed Science》 CAS 2010年第2期23-25,共3页
[ Objective] To investigate the effects of traditional Chinese medicine compound preparation on serum biochemical indexes and egg nutri- tional quality of laying hens. [Method] A total of 1 200 chickens at the age of ... [ Objective] To investigate the effects of traditional Chinese medicine compound preparation on serum biochemical indexes and egg nutri- tional quality of laying hens. [Method] A total of 1 200 chickens at the age of 44 weeks were selected and randomly divided into five groups. After administration with different dosages of astragalus polysaccharides and berberine for 9 weeks, serum biochemical indexes were determined and nu- trient contents of egg were detected. [ ltesultl The contents of total protein, globulin, high-density lipoprotein cholesterol (HDL-C) and alkaline phosphatase (ALP) in all treatment groups were significantly ( P 〈 0.05 or 0.01 ) higher than those in the control group. The cholesterol contents of all treatment groups were significantly ( P 〈 0.05 or 0.01 ) lower than those of the control group. E Conclusion~ The optimal concentrations of as- tragalus polysacchaddes and berberine in basic diets are 200 and 30 mg/kg, respectively. 展开更多
关键词 Astragalus polysaccharides BERBERINE serum biochemical indexes Egg nutritional quality
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Parameters Influencing Haematological, Serum and Bio-Chemical References in Livestock Animals under Different Management Systems 被引量:3
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作者 Gbolabo O. Onasanya Florence O. Oke +1 位作者 Timothy M. Sanni Aliyu I. Muhammad 《Open Journal of Veterinary Medicine》 2015年第8期181-189,共9页
Serum bio-chemical and haematological indices constitute important panels in the diagnosis, prognosis and treatment of livestock diseases via the investigations of myriads of parameters influencing these blood and ser... Serum bio-chemical and haematological indices constitute important panels in the diagnosis, prognosis and treatment of livestock diseases via the investigations of myriads of parameters influencing these blood and serum bio-chemical indices. Serum bio-chemical indices, haematological indices and blood electrolytes are critical physiological indices which have health implications on the diagnosis, prognosis and treatment of livestock diseases especially in animals bred under different management systems. It is important to stress that cascades of parameters of both genetic and non-genetic origin greatly have direct and in-direct health implications on serum bio-chemical indices and blood electrolytes in livestock animals and subsequently on their health/ production performances. Laboratory blood tests would be a vital tool to help detect any deviation from normal state of wellbeing in animals. Therefore, this review intends to provide base line information to establish certain haematological and serum bio-chemical indices as standard references which can be employed as alternative therapy for diagnosis, prognosis and treatment of cascades of diseases plaguing livestock animals bred under different management systems especially under the harsh condition of the tropics. Hence, it is important to establish standard values for the various blood and serum bio-chemical indices base on parameters of non-genetic origin;age, sex, physiological state, stress level, management systems, medication, health status, nutrition, hormone, climate, etc. and genetic parameters which include the breed and genotype of the animal among others obviously affect the blood and serum profile of healthy animal which subsequently influence their production performance and efficiency. 展开更多
关键词 Haematological Indices serum bio-chemical Indices Diagnosis Blood Electrolytes Physiological Indices
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Effects of Fermentation Bed Padding on Intestinal Flora,Serum Biochemical Indexes and Immune Function of Growing-finishing Pigs 被引量:1
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作者 Guo Tongi Tian Jin +1 位作者 Li Lingyan Li Xiaochen 《Animal Husbandry and Feed Science》 CAS 2020年第3期1-5,共5页
[Objective]The paper was to study the effects of fermentation bed padding on intestinal flora,serum biochemical indexes and immune function of growing-finishing pigs.[Method]A total of 90 growing-finishing pigs(Duroc ... [Objective]The paper was to study the effects of fermentation bed padding on intestinal flora,serum biochemical indexes and immune function of growing-finishing pigs.[Method]A total of 90 growing-finishing pigs(Duroc × Landrace × Yorkshire)with the body weight of(30.5±0.8)kg were randomly divided into five groups,three replicates each group,six pigs each replicate.The padding of five groups were:50%rice husk+50%sawdust(control group),100%spent mushroom substrate of Pleurotus eryngii(100%spent mushroom substrate group),15%rice husk+15%sawdust+70%spent mushroom substrate(70%spent mushroom substrate group),25%rice husk+25%sawdust+50%spent mushroom substrate(50%spent mushroom substrate group),35%rice husk+35%sawdust+30%spent mushroom substrate(30%spent mushroom substrate group).The pre-trial lasted 7 d,and the formal trial lasted 90 d.[Result]Compared with the control group,the number of Escherichia col in 100%,70%and 50%spent mushroom substrate groups decreased by 35.4%,24.0%and 20.8%,respectively(P<0.05);the number of salmonella successively decreased by 29.4%,19.3%and 15.2%,respectively(P<0.05);the number of lactobacillus successively increased by 21.7%,15.9%and 12.2%,respectively(P<0.05);and the number of bifidobacteria successively increased by 20.2%,16.7%and 11.8%,respectively(P<0.05).Compared with the control group,the total serum protein content in 100%,70%,50%and 30%spent mushroom substrate groups increased by 30.6%,33.0%,28.0%and 18.4%,respectively(P<0.05);and the serum urea nitrogen content decreased by 32.4%,34.5%,33.9%and 22.0%,respectively(P<0.05).There was no significant difference in serum albumin,aspartate aminotransferase(AST)and alanine aminotransferase(ALT)between treatment groups and control group.The IgA,IgG,IgM and IL-6 levels in serum of each treatment group were significantly different from those of the control group(P<0.05).There was no significant difference in IgA,IgG,IgM and IL-6 levels among 100%,70%and 50%spent mushroom substrate groups.[Conclusion]It improves the balance of intestinal microecological flora of growing-finishing pigs and enhances the immune performance of pigs by using spent mushroom substrate of P.eryngii as the fermentation bed padding.15%rice husk+15%sawdust+70%spent mushroom substrate is the optimal proportion of spent mushroom substrate for growing-finishing pigs. 展开更多
关键词 Fermentation bed PADDING Growing-finishing pig Intestinal flora serum biochemical indexes Immune function
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EFFECTS OF INHALED TiO_2 NANOTUBES ON LUNG TISSUE AND SERUM BIOCHEMICAL INDEXES OF MICE
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作者 陶杰 何娉婷 +2 位作者 张焱焱 汤育欣 王月勤 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2013年第1期96-103,共8页
To evaluate the acute lung toxicity and the effect on serum biochemical indexes of inhaled TiO2 nanotubes , healthy and adult Kunming mice are exposed to aerosols of TiO2nanotubes in a sealed chamber , the concentrati... To evaluate the acute lung toxicity and the effect on serum biochemical indexes of inhaled TiO2 nanotubes , healthy and adult Kunming mice are exposed to aerosols of TiO2nanotubes in a sealed chamber , the concentration of which is 250mg / m 3 while another group of mice are exposed to room air only served as control.The blood , alveolar lavaged fluid and lungs of the mice are collected and examined after exposed for 7 , 14and 28d , respectively.The serum analysis shows that glucose ( Glu ) values with 7dexposure , alanine aminotransferase ( ALT ) and aspartate aminotransferase ( AST ) activities with 28dinhalation , and total bile acid ( TBA ) values with 7 , 28d as well as the creatine kinase ( CK ) levels with 28dexposure are significantly different from those of controls ( P< 0.05 ) .The pathological findings exhibit that more TiO 2 nanotubes are found in the interstitium of pulmonary alveoli with the experimental time prolonged.The results suggest that TiO 2 nanotubes do produce adverse responses to the lung and serum biochemical indexes of mice.Moreover , the responses become severer with the exposed-time prolonged. 展开更多
关键词 NANOMATERIALS titanium dioxide nanotubes pulmonary toxicity serum biochemical indexes INHALATION
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Effects of Dietary Picria felterrae Lour Extracts on Serum Biochemical Indexes and Immune Function of Guangxi Partridge Chickens
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作者 Yang Cui Bi Xianda +9 位作者 Hu Tingjun Yang Jian Huang Hongye Tan Honglian Peng Jianbo Luo Wenjuan Li Lu Li Chunjie Liao Yuying Yang Jiahuang 《Animal Husbandry and Feed Science》 CAS 2018年第1期52-57,共6页
[Objective] This trial was to investigate the effect of dietary Picria felterrae Lour extracts on serum biochemical indexes and immune function of Guangxi Partridge chickens. [Method] Totally 500 individuals of 1-day-... [Objective] This trial was to investigate the effect of dietary Picria felterrae Lour extracts on serum biochemical indexes and immune function of Guangxi Partridge chickens. [Method] Totally 500 individuals of 1-day-old Guangxi Partridge chickens were randomly divided into five groups, five replicates each group and 20 chicks each replicate. Groups A, B and C were treatment groups supplemented with 0.70%, 0.35% and0.175% P. felterrae extracts in the basal diet, respectively; group D was a medical control group supplemented with 0.01% colistin sulfate premix in the basal diet; and group E was a control group with basal diet. Serum samples were collected from 10 chickens in each group at 21, 35 and 49 days of age, to analyze the biochemical and immune indexes. [Result] It had no significant impact on serum TP and GLU contents of chickens by adding different levels of P. felterrae extracts in the basal diet(P 〉0.05). However, at 21 and 35 days of age, the TBILI content of chickens in groups A, B and C were extremely lower or significantly lower than that in group E( P〈0.01; P〈0.05). At 35 days of age, the serum AKP activities in groups A, B and C were extremely higher than that in group E(P〈0.01), and the serum GOT activities at 21 and 35 days of age in group C were significantly higher than that in group E(P〈0.05). At 49 days of age, the serum Ig G content in groups A, B and C and the IL-2 content in group B and group C were significantly lower or extremely lower than that in group E( P〈0.05; P〈0.01); the T-AOC content in group B was significantly higher than that in group E(P〈0.05); the GSH content in groups A, B and C were significantly higher than that in group E( P〈0.05). Adding different levels of P. felterrae extracts in the diet significantly decreased the TBILI content, reduced the Ig G, IL-2 and IL-6 contents, and improved the AKP and GOT activities and the T-AOC and GSH contents of Guangxi Partridge chicken. [Conclusion] Adding 0.35% P. felterrae extracts in the basal diet received the best effort. 展开更多
关键词 Picria felterrae Lour extracts Guangxi Partridge chicken serum biochemical index Immune index Antioxidant ability
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Correlation of serum albumin and prognostic nutritional index with outcomes following pancreaticoduodenectomy 被引量:7
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作者 Narongsak Rungsakulkij Pongsatorn Tangtawee +3 位作者 Wikran Suragul Paramin Muangkaew Somkit Mingphruedhi Suraida Aeesoa 《World Journal of Clinical Cases》 SCIE 2019年第1期28-38,共11页
BACKGROUND Pancreaticoduodenectomy(PD) is a complex surgical procedure with a high morbidity rate. The serious complications are major risk factors for poor longterm surgical outcome. Studies have reported an associat... BACKGROUND Pancreaticoduodenectomy(PD) is a complex surgical procedure with a high morbidity rate. The serious complications are major risk factors for poor longterm surgical outcome. Studies have reported an association between early postoperative prognostic nutritional index(PNI) and prediction of severe complications after abdominal surgery. However, there have been no studies on the use of early postoperative PNI for predicting serious complications following PD.AIM To analyze the risk factors and early postoperative PNI for predicting severe complications following PD.METHODS We retrospectively analyzed 238 patients who underwent PD at our hospital between January 2007 and December 2017. The postoperative complications were classified according to the Dindo-Clavien classification. Grade Ⅲ-Ⅴ postoperative complications were classified as serious. The risk factors for serious complications were analyzed by univariate analysis and multivariate logistic regression analysis.RESULTS Overall complications were detected in 157 of 238 patients(65.9%) who underwent PD. The grade Ⅲ-Ⅴ complication rate was 26.47%(63/238 patients).The mortality rate was 3.7%(9/238 patients). Multivariate logistic regression analysis revealed that preoperative serum albumin [odds ratio(OR): 0.883, 95%confidence interval(CI): 0.80-0.96; P < 0.01] and PNI on postoperative day 3 <40.5(OR: 2.77, 95%CI: 1.21-6.38, P < 0.05) were independent factors associated with grade Ⅲ-Ⅴ postoperative complications.CONCLUSION Perioperative albumin is an important factor associated with serious complications following PD. Low early postoperative PNI(< 40.5) is a predictor for serious complications. 展开更多
关键词 POSTOPERATIVE complications PANCREATECTOMY serum ALBUMIN Risk factors PROGNOSTIC NUTRITIONAL index
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Body mass index and serum lipid profile influence serum prostate-specific antigen in Chinese men younger than 50 years of age 被引量:5
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作者 Ming Liu Jian-Ye Wang +1 位作者 Ling Zhu Gang Wan 《Asian Journal of Andrology》 SCIE CAS CSCD 2011年第4期640-643,共4页
This study is to assess the potential factors that could affect the serum prostate-specific antigen (PSA) level in healthy younger men. We evaluated the associations of age, body mass index (BMI) and serum lipid p... This study is to assess the potential factors that could affect the serum prostate-specific antigen (PSA) level in healthy younger men. We evaluated the associations of age, body mass index (BMI) and serum lipid profile with serum PSA level in 6774 Chinese men (aged 20-49 years) who received a routine health examination. Eligible men were classified into 10-year age groups, BMI was categorized as underweight (〈18.5), normal (18.5-22.9), overweight (23.0-24.9), obese (25.0-29,9) and very obese (〉30) according to the redefined World Health Organization (WHO) criteria for the Asia-Pacific region. PSA levels were compared among groups as well, In multiple linear regression analysis, PSA was positively correlated with age (P〈0.0001). Negative correlations existed between PSA and BMI (P〈0.0001) and triglyceride level (P=0.01). No relationship could be found between PSA and serum cholesterol (P=0.711) or high-density lipoprotein (HDL; P =0.665). In addition, we found that serum PSA levels increased with age and decreased with BMI. Our study demonstrates that age, BMI and triglyceride levels influence the PSA level in men 〈50 years of age. 展开更多
关键词 age body mass index prostate-specific antigen serum lipid profile
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Effects of Dietary Crude Fiber Levels on Growth Performance and Serum Biochemical Index of Dingan Geese Aged from 35 to 70 Days 被引量:3
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作者 Liu Quanwei Wang Feng +5 位作者 Wei Limin Lin Dajie Xing Manping Yang Shaoxiong Sun Ruiping Ye Baoguo 《Animal Husbandry and Feed Science》 CAS 2019年第1期12-15,共4页
[Objective] The study was carried out to investigate the effects of dietary crude fiber on growth performance and serum biochemical in-dex of Dingan geese aged from 35 to 70 days.[Method] A total of 120 Dingan geese o... [Objective] The study was carried out to investigate the effects of dietary crude fiber on growth performance and serum biochemical in-dex of Dingan geese aged from 35 to 70 days.[Method] A total of 120 Dingan geese on day 28 with the same genetic background and similar initial weight(1 384.83.73±0.76 g) were randomly assigned into 3 groups, with 4 replicates per group and 10 geese per replicate. Geese were fed the diets containing 4.29%, 5.29% and 6.29 % crude fiber, respectively. The experiment lasted 35 d.[Result] Final weight and daily gain of 5.29 %CF group were significantly higher than those of 6.29 % CF group(P<0.05);Feed intake was markedly higher than those of 4.29% and 6.29 % CF groups(P<0.05);Feed gain ratio was significantly lower than that of 6.29 % CF group(P<0.05). Compared with 4.29% and 6.29 % CF groups, serum albumin concentrations of 5.29 % CF group increased significantly(P<0.05), while serum total protein and globin contents were higher(P>0.05), but serum uric acid level was lower(P>0.05).[Conclusion] 5.29 % crude fiber could lead to higher growth performance of Dingan geese. 展开更多
关键词 CRUDE fiber Dingan GEESE Growth performance serum BIOCHEMICAL index
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Effects of Crude Fiber Levels on Production Performance, Organ Index and Serum Biochemical Parameters of Dingan Geese Aged from 1 to 28 Days 被引量:1
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作者 Liu Quanwei Wei Limin +5 位作者 Wang Feng Lin Dajie Xing Manping Yang Shaoxiong Sun Ruiping Ye Baoguo 《Animal Husbandry and Feed Science》 CAS 2019年第3期98-102,共5页
[Objective]The paper was to investigate the effects of dietary crude fiber level on production performance,organ index and serum biochemical parameters of Dingan geese aged from 1 to 28 days.[Method]A total of 144 1-d... [Objective]The paper was to investigate the effects of dietary crude fiber level on production performance,organ index and serum biochemical parameters of Dingan geese aged from 1 to 28 days.[Method]A total of 144 1-day-old Dingan geese with the same genetic background and similar initial weight(88.75±0.21g)were randomly assigned into 3 groups with 4 replicates per group and 12 geese per replicate,and fed with the diets containing 2.56%,3.52% and 4.48% crude fiber,respectively.The trial lasted 28 d.[Result]1)The final weight and daily gain of 3.52% CF group were significantly higher than those of 2.56% CF group(P<0.05);the feed/gain ratio was markedly lower than that of 2.56% CF group(P<0.05).2)The slaughter rate,semi-eviscerated rate and leg muscle rate of 3.52% CF group were higher than those of 2.56% and 4.48% CF groups(P>0.05).3)As the dietary crude fiber levels rose,the abdominal fat rate showed a downward trend(P>0.05).4)The liver index of 3.52% CF group was significantly higher than that of 2.56% CF group(P<0.05).4)Compared with 2.5%and 4.48% CF groups,the serum albumin concentrations of 3.52% CF group markedly increased(P<0.05),the serum total protein and globin contents were higher(P>0.05),but the serum uric acid level was lower(P>0.05).[Conclusion]When the crude fiber level was 3.52%,the production performances of Dingan geese aged from 1 to 28 days were better,and the liver index and serum albumin level could be obviously improved. 展开更多
关键词 CRUDE fiber Dingan GEESE Production performance ORGAN index serum BIOCHEMICAL index
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Relationship Between Serum Leptin Concentration and Lipids & Body Mass Index in Patients With Chronic Congestive Heart Failure 被引量:1
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作者 李刚 严清波 魏良明 《South China Journal of Cardiology》 CAS 2006年第1期40-43,9,共5页
Objectives To investigate the relationship of serum leptin concentration with the lipids and body mass index (BMI) in patients with chronic congestive heart failure(CHF). Methods The serum concentration of leptin ... Objectives To investigate the relationship of serum leptin concentration with the lipids and body mass index (BMI) in patients with chronic congestive heart failure(CHF). Methods The serum concentration of leptin in 39 patients with CHF (14 in cardiac function class Ⅱ , 21 in class Ⅲ, 4 in classⅣ , NYHA) and in 46 patients with cardiac function class Ⅰ (NYHA) were assessed by radioimmunoassay. Results The serum concentration of leptin were 9.018±4.519 μg/l in CHF group (cardiac function class Ⅱ 11.492±5.649 μg/l, class Ⅲ 7.763±3.321 μg/l, class Ⅳ 6.100±2.657 μg/l); 11.674± 6.911 μg/l in class Ⅰ group. The serum concentrations of leptin were significantly lower in CHF group, as compared with class Ⅰ group (P〈 0.05). Moreover, the decrease of serum leptin concentration was significantly correlated with the decreased serum concentrations of total cholesterol, triglyceride, body mass index and left ventricular ejection fraction in CHF group, respectively (P 〈 0.05). Conclusions The significance of the decrease in serum leptin in CHF patients needs further study. 展开更多
关键词 Congestive heart failure Leptin serum lipids Body mass index
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Influence of reduced-port laparoscopic surgery on perioperative indicators, postoperative recovery, and serum inflammation in patients with colorectal carcinoma
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作者 Hong-Biao Wu Dong-Fang Liu +2 位作者 Ye-Lei Liu Xiao-Feng Wang Yue-Peng Cao 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第6期1734-1741,共8页
BACKGROUND Conventional five-port laparoscopic surgery,the current standard treatment for colorectal carcinoma(CRC),has many disadvantages.AIM To assess the influence of reduced-port laparoscopic surgery(RPLS)on perio... BACKGROUND Conventional five-port laparoscopic surgery,the current standard treatment for colorectal carcinoma(CRC),has many disadvantages.AIM To assess the influence of reduced-port laparoscopic surgery(RPLS)on perioperative indicators,postoperative recovery,and serum inflammation indexes in patients with CRC.METHODS The study included 115 patients with CRC admitted between December 2019 and May 2023,52 of whom underwent conventional five-port laparoscopic surgery(control group)and 63 of whom underwent RPLS(research group).Comparative analyses were performed on the following dimensions:Perioperative indicators[operation time(OT),incision length,intraoperative blood loss(IBL),and rate of conversion to laparotomy],postoperative recovery(first postoperative exhaust,bowel movement and oral food intake,and bowel sound recovery time),serum inflammation indexes[high-sensitivity C-reactive protein(hs-CRP),tumor necrosis factor-α(TNF-α),and interleukin-6(IL-6)],postoperative complications(anastomotic leakage,incisional infection,bleeding,ileus),and therapeutic efficacy.RESULTS The two groups had comparable OTs and IBL volumes.However,the research group had a smaller incision length;lower rates of conversion to laparotomy and postoperative total complication;and shorter time of first postoperative exhaust,bowel movement,oral food intake,and bowel sound recovery;all of which were significant.Furthermore,hs-CRP,IL-6,and TNF-αlevels in the research group were significantly lower than the baseline and those of the control group,and the total effective rate was higher.CONCLUSION RPLS exhibited significant therapeutic efficacy in CRC,resulting in a shorter incision length and a lower conversion rate to laparotomy,while also promoting postoperative recovery,effectively inhibiting the inflammatory response,and reducing the risk of postoperative complications. 展开更多
关键词 Reduced-port laparoscopic surgery Colorectal carcinoma Perioperative indicators Postoperative recovery serum inflammation indexes
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Effects of Serum Calcium and Phosphorus under Different Feeding Conditions on Production Traits of Young Xinjiang Brown Bulls
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作者 居来提.阿不都外力 任万平 +2 位作者 张浩 吕强 余雄 《Agricultural Science & Technology》 CAS 2014年第4期668-671,677,共5页
[Objective] In the Xinjiang new era from October 2012 to February 2013, agricultural and animal husbandry Co. Ltd. feedlot Yining Tuogelake village used tethered and scattered feeding methods to conduct fattening youn... [Objective] In the Xinjiang new era from October 2012 to February 2013, agricultural and animal husbandry Co. Ltd. feedlot Yining Tuogelake village used tethered and scattered feeding methods to conduct fattening young Xinjiang brown cattle experiment. [Method] The 16-month-old young Xinjiang brown bulls were se- lected totaling 68 heads, divided into scattered group and tethered group. Male claves were taken as test subjects from October to February of following year and body conformation linear evaluation were made, followed by measurement of body size indexes and Regular collection of Blood samples. [Result] In the two feeding ways, scattered group feeding improved the ADG of youth Xinjiang brown cattle bull calf (P〈0.01), and the whole calf ADG 845.58g was significantly higher than that in tethered group at 619.11g, increasing by 36.58%; furthermore, scattered group in the December, January and February average daily weight gain was significantly higher compared with the tethered group at 13.61%, 32.32%, 53.47%, respectively. Scattered group feeding significantly increased the young calf serum phosphorus content (P〈0.01), higher than the tethered group at 0.62%, 7.89%, 14.29% in February, December and January respectively. But the tethered feeding young cattle serum phosphorus content gradually declined. Of the two groups, male calf serum calcium content had little effects on the serum calcium with insignificant difference (P〉0.05). Bulls by scattered feeding method was proved faster and better in the whole growth period, in terms of body height, body length, circumference, leg cir- cumference, rump length, waist high, sciatic wide, hip width basically in the contin- ued growth trend. [Conclusion] Scattered feeding can significantly improve the young Xinjiang brown cattle's daily gain, and accelerate the body height, heart girth and body length etc body growth. What's more, scattered feeding serum calcium and phosphorus content are significantly higher than tethered feeding. 展开更多
关键词 Tethered SCATTERED serum calcium serum phosphorus Body size index
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Inverted U-Shaped Associations between Glycemic Indices and Serum Uric Acid Levels in the General Chinese Population:Findings from the China Cardiometabolic Disease and Cancer Cohort(4C)Study 被引量:3
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作者 ZHU Yuan Yue ZHENG Rui Zhi +36 位作者 WANG Gui Xia CHEN Li SHI Li Xin SU Qing XU Min XU Yu CHEN Yu Hong YU Xue Feng YAN Li WANG Tian Ge ZHAO Zhi Yun QIN Gui Jun WAN Qin CHEN Gang GAO Zheng Nan SHEN Fei Xia LUO Zuo Jie QIN Ying Fen HUO Ya Nan LI Qiang YE Zhen ZHANG Yin Fei LIU Chao WANG You Min WU Sheng Li YANG Tao DENG Hua Cong ZHAO Jia Jun CHEN Lu Lu MU Yi Ming TANG Xu Lei HU Ru Ying WANG Wei Qing NING Guang LI Mian LU Jie Li BI Yu Fang 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2021年第1期9-18,共10页
Objective The relationship between serum uric acid(SUA)levels and glycemic indices,including plasma glucose(FPG),2-hour postload glucose(2 h-PG),and glycated hemoglobin(HbA1 c),remains inconclusive.We aimed to explore... Objective The relationship between serum uric acid(SUA)levels and glycemic indices,including plasma glucose(FPG),2-hour postload glucose(2 h-PG),and glycated hemoglobin(HbA1 c),remains inconclusive.We aimed to explore the associations between glycemic indices and SUA levels in the general Chinese population.Methods The current study was a cross-sectional analysis using the first follow-up survey data from The China Cardiometabolic Disease and Cancer Cohort Study.A total of 105,922 community-dwelling adults aged≥40 years underwent the oral glucose tolerance test and uric acid assessment.The nonlinear relationships between glycemic indices and SUA levels were explored using generalized additive models.Results A total of 30,941 men and 62,361 women were eligible for the current analysis.Generalized additive models verified the inverted U-shaped association between glycemic indices and SUA levels,but with different inflection points in men and women.The thresholds for FPG,2 h-PG,and HbA1 c for men and women were 6.5/8.0 mmol/L,11.0/14.0 mmol/L,and 6.1/6.5,respectively(SUA levels increased with increasing glycemic indices before the inflection points and then eventually decreased with further increases in the glycemic indices).Conclusion An inverted U-shaped association was observed between major glycemic indices and uric acid levels in both sexes,while the inflection points were reached earlier in men than in women. 展开更多
关键词 Cross-sectional study serum uric acid Glycemic index Glycemic status
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Serum Ion Concentrations and Antioxidation of Dairy Cows with Retained Fetal Placenta 被引量:1
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作者 ZHANG Shou WANG Yong +2 位作者 LU Fu-shan LI Yue-yun LI Long 《Animal Husbandry and Feed Science》 CAS 2010年第2期32-34,共3页
[ Objective] TO further explore the mechanism of retained fetal membrane (RFM) of dairy cows in Qinghai Province. [ Methed] As many as 15 dairy cows with retained fetal placenta and 15 without retained fetal placent... [ Objective] TO further explore the mechanism of retained fetal membrane (RFM) of dairy cows in Qinghai Province. [ Methed] As many as 15 dairy cows with retained fetal placenta and 15 without retained fetal placenta were selected. The serum concentrations of eight metal ions, namely, potassium, sodium, calcium, magnesium, copper, iron, zinc and manganese at parturition and 12 h post partum were determined by atomic absorption spectrometry. The anti-oxidative indexes at parturition were determined by UV-1601 doub|e-beam visib|e spectrophotometer. ~=- sultl In the dairy cows with retained fetal placenta, the concentrations of calcium, magnesium, copper, zinc and manganese were decreased signif- icantly ( P 〈 0.05) ; that of iron was increased significantly ( P 〈 0.01 ) ; those of potassium and sodium did not change greatly; the activities of su- peroxide dismutase and glutathione peroxidase were decreased significantly ( P 〈 0.01 ) ; and the MDA content was increased significantly ( P 〈 0.05). However, the concentrations of the eight metal ions and anti-oxidative indexes did not change in the dairy cows without retained fetal placen- ta, [ CondusionJ The RFM of dairy cows has some relationships with the serum concentrations of metal ions and antioxidation. 展开更多
关键词 Dairy cows Retainecl fetal placenta serum Metal ions Anti-oxidative indexes
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Effects of High Dietary Fluoride on Serum Biochemistry and Oxidative Stress Parameters in Broiler Chickens 被引量:1
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作者 Yubing Deng Hengmin Cui +4 位作者 Xi Peng Jing Fang Zhicai Zuo Junliang Deng Qin Luo 《Health》 2014年第14期1840-1848,共9页
The aim of this study was to investigate the effects of high dietary fluoride (F) on serum biochemistry and oxidative damage in broiler chickens. 280 one-day-old healthy avian broiler chickens were randomly allotted i... The aim of this study was to investigate the effects of high dietary fluoride (F) on serum biochemistry and oxidative damage in broiler chickens. 280 one-day-old healthy avian broiler chickens were randomly allotted into four equal groups and fed with a corn-soybean basal diet containing 22.6 mg·F/kg (control group) or same basal diets supplemented with 400, 800, and 1200 mg·F/kg (high F groups I, II, and III) in the form of sodium fluoride for 42 days. At 42 days of age, the serum F content was markedly higher in the three high F groups than that in the control group. From 28 to 42 days of age, the contents of serum total protein (TP) and albumin (ALB) were significantly lower in the three high F groups. From 14 to 42 days of age, the activities of alkaline phosphatase (ALP), alanine aminotransferase (ALT) and the creatinine (Crea) contents in the serum showed a marked increase in the three high F groups;aspartate aminotransferase (AST) activity and uric acid (Ua) content were significantly increased, and a significant increase in the content of malondialdehyde (MDA) along with marked decreases in the activities of total superoxide dismutase (T-SOD), glutathione peroxidase (GSH-Px), catalase (CAT), the glutathione (GSH) content and the ability to inhibit hydroxyl radical were observed in the high F groups II and III. In conclusion, F has accumulated in the blood circulatory system and dietary F in the range of 800 - 1200 mg/kg could significantly induce abnormalities of bone, liver and kidney, inhibit the synthesis of protein, enhance lipid peroxidation and disturb the antioxidative system of broiler chickens. 展开更多
关键词 BIOCHEMICAL indexes BROILER CHICKENS HIGH DIETARY FLUORIDE Oxidative Stress serum
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Association between Serum Uric Acid to HDL-Cholesterol Ratio and Nonalcoholic Fatty Liver Disease Risk among Chinese Adults 被引量:1
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作者 ZHAO Hui QIU Xia +2 位作者 LI Hua Zi CUI Jia Jia SUN Yong Ye 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2023年第1期1-9,共9页
Objective The aim of this case-control study was to explore the association between serum uric acid to high density lipoprotein cholesterol ratio(UHR) and the risk of nonalcoholic fatty liver disease(NAFLD) in Chinese... Objective The aim of this case-control study was to explore the association between serum uric acid to high density lipoprotein cholesterol ratio(UHR) and the risk of nonalcoholic fatty liver disease(NAFLD) in Chinese adults.Methods A total of 636 patients with NAFLD and 754 controls were enrolled from the Affiliated Hospital of Qingdao University, China, between January and December 2016. All patients completed a comprehensive questionnaire survey and underwent abdominal ultrasound examination and a blood test. NAFLD was diagnosed using ultrasonography after other etiologies were excluded. Logistic regression and restricted cubic spline model were conducted to evaluate the relationship of UHR with NAFLD risk.Results The multivariable adjusted odds ratio(95% confidence interval, CI) for NAFLD in the highest versus lowest quartile of UHR was 3.888(2.324–6.504). In analyses stratified by sex and age, we observed significant and positive associations between UHR and the risk of NAFLD in each subgroup. In analyses stratified by body mass index(BMI), a significant and positive association was found only in individuals with a BMI of ≥ 24 kg/m2. Our dose-response analysis indicated a linear positive correlation between UHR and the risk of NAFLD.Conclusion UHR is positively associated with the risk of NAFLD and may serve as an innovative and noninvasive marker for identifying individuals at risk of NAFLD. 展开更多
关键词 serum uric acid HDL-CHOLESTEROL The UHR index INFLAMMATION Nonalcoholic fatty liver disease
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Aspartate transferase-to-platelet ratio index-plus: A new simplified model for predicting the risk of mortality among patients with COVID-19 被引量:1
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作者 Ali Madian Ahmed Eliwa +1 位作者 Hytham Abdalla Haitham A Azeem Aly 《World Journal of Gastroenterology》 SCIE CAS 2022年第16期1671-1680,共10页
BACKGROUND Coronavirus disease 2019(COVID-19)has a spectrum of clinical syndromes with serious involvement of the lung and frequent effection of the liver and hemostatic system.Blood biomarkers are affordable,rapid,ob... BACKGROUND Coronavirus disease 2019(COVID-19)has a spectrum of clinical syndromes with serious involvement of the lung and frequent effection of the liver and hemostatic system.Blood biomarkers are affordable,rapid,objective,and useful in the evaluation and prognostication of COVID-19 patients.AIM To investigate the association between aspartate transferase-to-platelet ratio index(APRI)and in-hospital mortality to develop a COVID-19 mortality prediction model.METHODS A multicenter cohort study with a retrospective design was conducted.Medical records of all consecutive adult patients admitted to Al-Azhar University Hospital(Assiut,Egypt)and Chest Hospital(Assiut,Egypt)with confirmed COVID-19 from July 1,2020 to October 1,2020,were retrieved and analyzed.The patient cohort was classified into the following two categories based on the APRI:(1)COVID-19 presenting with APRI≤0.5;and(2)COVID-19 presenting with APRI(>0.5 and≤1.5).The association between APRI and all-cause in-hospital mortality was analyzed,and the new model was developed through logistic regression analyses.RESULTS Of the 353 patients who satisfied the inclusion criteria,10%were admitted to the intensive care unit(n=36)and 7%died during the hospital stay(n=25).The median age was 40 years and 50.7%were male.On admission,49%had aspartate transferase-dominant liver injury.On admission,APRI(>0.5 and≤1.5)was independently associated with all-cause in-hospital mortality in unadjusted regression analysis and after adjustment for age and sex;after stepwise adjustment for several clinically relevant confounders,APRI was still significantly associated with all-cause inhospital mortality.On admission,APRI(>0.5 and≤1.5)increased the odds of mortality by fivetimes(P<0.006).From these results,we developed a new predictive model,the APRI-plus,which includes the four predictors of age,aspartate transferase,platelets,and serum ferritin.Performance for mortality was very good,with an area under the receiver operating curve of 0.90.CONCLUSION APRI-plus is an accurate and simplified prediction model for mortality among patients with COVID-19 and is associated with in-hospital mortality,independent of other relevant predictors. 展开更多
关键词 COVID-19 Aspartate transferase-to-platelet ratio index Aspartate transferase All-cause inhospital mortality serum ferritin SARS-CoV-2
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Effects of hyperbaric oxygen on serum inflammatory factors, oxidative stress, endothelin and intracranial pressure in patients with severe head injury 被引量:1
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作者 Dai Liu Hu-Yin Yang 《Journal of Hainan Medical University》 2017年第5期83-86,共4页
Objective:To investigate the effect of hyperbaric oxygen (HBO) on serum inflammatory factors, oxidative stress status, endothelial cell function and intracranial pressure in patients with severe craniocerebral injury ... Objective:To investigate the effect of hyperbaric oxygen (HBO) on serum inflammatory factors, oxidative stress status, endothelial cell function and intracranial pressure in patients with severe craniocerebral injury (STBI), and to provide scientific basis for clinical treatment of patients with severe craniocerebral injury.Methods: 110 cases of STBI were selected and divided into control group and treatment group according to the random data table, 55 cases in each group. The control group received conventional combined therapy, the observation group were given HBO treatment on the base of the control group, the inflammatory factors [C reactive protein (CRP), tumor necrosis factor alpha (TNF-α), interleukin-6 (IL-6), and interleukin-10 (IL-10)] and oxidative stress [malondialdehyde (MDA) and superoxide dismutase-1 (SOD-1)], endothelin (ET) and intracranial pressure (ICP) level changes of the two groups were observed and compared before and after treatment for 10 d in patients. Results: The levels of CRP, TNF-α, IL-6, MDA, ET and ICP in the treatment group and the control group were significantly lower than those in the same group before treatment, the difference was statistically significant (P<0.05), the CRP, TNF-α, IL-6, MDA, ET and ICP levels of the observation group after treatment were significantly lower than the control group after treatment (P<0.05);After treatment, IL-10 and SOD-1 levels of the two groups of patients were significantly increased than the same group before treatment (P<0.05), and both levels in the observation group after treatment was significantly higher than the control group after treatment (P<0.05).Conclusions: HBO treatment of severe brain injury patients with significant effect, can effectively reduce oxidative stress damage and inflammation, improve patients' endothelial cell function, reduce intracranial pressure, and has a certain clinical value. 展开更多
关键词 SEVERE CRANIOCEREBRAL injury HYPERBARIC oxygen therapy CURATIVE effect serum BIOCHEMICAL index
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Clinical value evaluation of serum markers for early diagnosis of colorectal cancer
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作者 Wen-Yue Song Xin Zhang +2 位作者 Qi Zhang Peng-Jun Zhang Rong Zhang 《World Journal of Gastrointestinal Oncology》 SCIE CAS 2020年第2期219-227,共9页
BACKGROUND Early screening for colorectal cancer(CRC)is important in clinical practice.However,the currently methods are inadequate because of high cost and low diagnostic value.AIM To develop a new examination method... BACKGROUND Early screening for colorectal cancer(CRC)is important in clinical practice.However,the currently methods are inadequate because of high cost and low diagnostic value.AIM To develop a new examination method based on the serum biomarker panel for the early detection of CRC.METHODS Three hundred and fifty cases of CRC,300 cases of colorectal polyps and 360 cases of normal controls.Combined with the results of area under curve(AUC)and correlation analysis,the binary Logistic regression analysis of the remaining indexes which is in accordance with the requirements was carried out,and discriminant analysis,classification tree and artificial neural network analysis were used to analyze the remaining indexes at the same time.RESULTS By comparison of these methods,we obtained the ability to distinguish CRC from healthy control group,malignant disease group and benign disease group.Artificial neural network had the best diagnostic value when compared with binary logistic regression,discriminant analysis,and classification tree.The AUC of CRC and the control group was 0.992(0.987,0.997),sensitivity and specificity were 98.9%and 95.6%.The AUC of the malignant disease group and benign group was 0.996(0.992,0.999),sensitivity and specificity were 97.4%and 96.7%.CONCLUSION Artificial neural network diagnosis method can improve the sensitivity and specificity of the diagnosis of CRC,and a novel assistant diagnostic method was built for the early detection of CRC. 展开更多
关键词 Colorectal cancer serum index BIOMARKER Artificial neural network
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