VR环境下SET GO教学法的构建及在耳鼻喉临床教学的应用

SET GO教学法也称为应诊录像教学法,就是在教学过程中,通过观察操作者的视频录像,进行教学的教学法。由于耳、鼻、喉的结构复杂,内部空间狭小,增加了视频录制的难度。在此背景下,吉林药学院附属医院将VR技术融入SET GO教学法中,借助VR技术录制成三维视频,使录制的视频清晰度更高,为SET GO教学法的实施提供了可行性。具体的教学环节分为前期教学、VR模拟操作及录制、VR录像加工、See和Else教学环节、Think教学环节、Goals和Offers教学环节等。通过以上环节的有序实施,提高了耳鼻喉科的临床教学效果。如在视频录制质量评价和SET GO教学效果评价方面,学生各项指标评价的良好率均在90%以上。建议进一步推广和应用。

基于AGREEⅡ和RIGHT对医患沟通指南的质量评价研究

目的对医患沟通的临床实践指南进行方法学和报告质量评价,以期确定高质量指南,提供临床参考。方法通过检索MEDLINE(PubMed)、Web of Science、中国知网(CNKI)、万方数据知识服务平台、维普(VIP),补充医脉通、用药助手、丁香园网站的相关临床实践指南(CPG),使用AGREEⅡ和RIGHT工具进行指南质量评价,采用组内相关系数(ICC)用于评估评审者对每个项目理解的一致性。结果共纳入2份临床实践指南,每个领域的评审人员的总体一致性是可以接受的。AGREEⅡ评价结果显示,2篇指南推荐级别均为B级,CPG所有7个领域的平均报告率为50.64%,其中领域1最高(88.89%),领域3最低(30.95%)。RIGHT评价结果显示,指南平均报告率为29.22%。结论医患沟通相关指南质量与数量仍有待提高,指南制订者应严格按照AGREEⅡ和RIGHT的要求规范撰写,以期提出高水平、高标准的循证指南,来指导医护人员的临床实践。

SETD5介导AKT1磷酸化调控结肠癌细胞的迁移和5-FU敏感性

目的:探讨含SET结构域蛋白5(SETD5)对结肠癌细胞增殖、迁移和对5-氟尿嘧啶(5-FU)药物敏感性的影响及机制。方法:常规培养结肠癌细胞,用Lipofectamine 2000将siSETD5-NC、si-SETD5-1~3质粒转染至HT-29细胞中,将其分为对照组(未处理)、si-SETD5-NC组、si-SETD5组和si-SETD5+SC79组,si-SETD5+SC79组HT-29细胞转染质粒的同时用10µmol/L SC79处理。qPCR法检测NCM460、HT-29和LoVo细胞中SETD5 mRNA表达,流式细胞术、细胞划痕法、WB法和CCK-8法分别检测各组HT-29细胞的凋亡情况、迁移能力、相关蛋白的表达,以及对5-FU的敏感性。结果:SETD5 mRNA在HT-29、LoVo细胞中均呈高表达(均P<0.01)。在HT-29细胞中成功地敲减了SETD5 mRNA(P<0.01)。敲减SETD5 mRNA可明显抑制HT-29细胞的增殖活性(P<0.01)、迁移能力(P<0.01)、相关蛋白(SETD5、p-PI3K、p-AKT1、p-mTOR蛋白)的表达(均P<0.01)、促进细胞凋亡(P<0.01),且提高其对5-FU的敏感性(P<0.01),这些作用均可被AKT激活剂SC79部分阻挡(P<0.05或P<0.01)。结论:SETD5在HT-29、LoVo细胞中高表达,SETD5通过PI3K/AKT1通路促进结肠癌HT-29细胞的增殖、迁移,且降低其对5-FU的敏感性,SETD5是结肠癌临床诊断、治疗的潜在靶点。

基于SET-AHP-TRIZ的坐式康复训练器设计研究

为解决现有坐式康复训练器形式与功能单一、操作使用缺乏智能化等问题,文章构建了基于SET-AHP-TRIZ的设计思路。首先,对产品的现状、用户进行市场调研,采用SET分析法确定目标产品的机会缺口;其次,应用AHP法对需求点进行定量计算,以确定创新过程中需要着重改善的问题;最后,通过应用TRIZ理论分析出现的矛盾问题,并总结其矛盾类型,利用发明原理解决问题,进行坐式康复训练器设计实践,减少了设计过程主观因素的影响,使设计结果更为科学合理,以期提高用户的满意度。

Federated Learning Model for Auto Insurance Rate Setting Based on Tweedie Distribution

In the assessment of car insurance claims,the claim rate for car insurance presents a highly skewed probability distribution,which is typically modeled using Tweedie distribution.The traditional approach to obtaining the Tweedie regression model involves training on a centralized dataset,when the data is provided by multiple parties,training a privacy-preserving Tweedie regression model without exchanging raw data becomes a challenge.To address this issue,this study introduces a novel vertical federated learning-based Tweedie regression algorithm for multi-party auto insurance rate setting in data silos.The algorithm can keep sensitive data locally and uses privacy-preserving techniques to achieve intersection operations between the two parties holding the data.After determining which entities are shared,the participants train the model locally using the shared entity data to obtain the local generalized linear model intermediate parameters.The homomorphic encryption algorithms are introduced to interact with and update the model intermediate parameters to collaboratively complete the joint training of the car insurance rate-setting model.Performance tests on two publicly available datasets show that the proposed federated Tweedie regression algorithm can effectively generate Tweedie regression models that leverage the value of data fromboth partieswithout exchanging data.The assessment results of the scheme approach those of the Tweedie regressionmodel learned fromcentralized data,and outperformthe Tweedie regressionmodel learned independently by a single party.

MTA2、SET8蛋白在喉癌中的表达及与临床病理特征的关系

目的探讨MTA2、SET8蛋白在喉癌中的表达及与临床病理特征的关系。方法收集喉癌患者205例作为研究对象,采用免疫组织化学染色法检测MTA2、SET8阳性蛋白,采用Real-time PCR检测MTA2、SET8 mRNA表达水平。分析MTA2、SET8蛋白表达与喉癌患者临床病理特征的关系。Spearson相关性分析MTA2蛋白与SET8蛋白表达之间的关系。结果喉癌组MTA2、SET8蛋白阳性表达率(56.10%、54.15%)显著高于癌旁组,差异均有统计学意义(χ^(2)=27.926,P<0.001;χ^(2)=28.277,P<0.001);喉癌组MTA2、SET8 mRNA表达水平高于癌旁组,差异均具有统计学意义(t=25.005,P<0.001;t=20.390,P<0.001)。喉癌组织中MTA2、SET8蛋白阳性表达与性别、年龄、是否吸烟、临床分型均无关(P>0.05),与淋巴结是否转移、病理分级、临床分期有关(P<0.05)。Spearson相关性分析显示,MTA2蛋白与SET8蛋白表达呈现正相关(γ=0.477,P<0.05)。结论MTA2、SET8蛋白在喉癌中表达明显上升,且与喉癌的发展密切相关,预示其可能成为诊断分子的潜能。

Addressing Japan’s disposal of nuclear-contaminated water from the perspective of international human rights law

The discharge of nuclear-contaminated water containing radionuclides into the ocean by Japan will lead to its integration into the entire ecosystem through processes of circulation and biomagnification,eventually entering the human body via the food chain.This poses a substantial risk of irreversible damage to both the ecosystem and human health,a situation that will worsen with the ongoing discharge of such water.The respect and protection of human rights represent an international consensus,and safeguarding fundamental human rights is a substantial obligation that states must undertake in accordance with both international and domestic law.Since the Fukushima nuclear disaster,Japan has continuously violated its international legal obligations to protect human rights in several areas,including the resettlement of disaster victims,the reduction of nuclear radiation levels,and the handling of contaminated water.Such actions have compromised and will continue to compromise the basic human rights of not only its citizens but also those of people worldwide,including environmental rights,the right to life,development rights,and food rights.In the aftermath of the Fukushima meltdown,the public and workers involved in handling nuclear contaminants have been continually exposed to high radiation levels,endangering their rights to life,development,and health.Japan’s inadequate efforts in victim resettlement and environmental restoration have jeopardized the environmental and food rights of its citizens to live healthily and access food in an environment unaffected by nuclear radiation.The release of nuclear-contaminated water poses a risk of Japan’s nuclear pollution to the people of neighboring countries and the global population at large.The principle of human rights underpins the theory of a community with a shared future for humanity,and human rights are a crucial area of China’s active participation in United Nations affairs and global governance.By voicing concerns over Japan’s potential human rights violations globally,China demonstrates its role as a responsible major country.In response to Japan’s breach of legal obligations and human rights violations,China can adopt a reasoned and beneficial approach,including calling on the international community to hold Japan criminally accountable for crimes against humanity under the Rome Statute and advancing scholarly discussions on ecocide and crimes against the marine environment.Furthermore,China should persist in seeking advisory opinions from the International Court of Justice and strive for substantive accountability,utilizing the mechanisms of international human rights organizations to make its voice heard.

双碳目标下减压渣油高值利用的RIGHT技术研发

炼油低碳转型发展的关键是高含碳重组分的高效高值利用。通过溶剂脱沥青技术把质量较差的常规焦化原料(即减压渣油)分为脱油沥青(DOA)和脱沥青油(DAO),然后利用相似相溶原理,把两种低价值的以芳烃结构为主的DOA和催化裂化轻循环油(LCO)混合进行加氢(组分炼油),同时DAO单独加氢,形成了中石化石油化工科学研究院有限公司一体化加氢RIGHT(RIPP InteGrated HydroTreating)技术。加氢后DOA进焦化装置可以生产低金属(V、Ni质量分数均小于150μg/g)或低金属低硫(硫质量分数不大于3.0%)的石油焦,为高端炭材料提供高质量前躯体。与常规焦化相比,RIGHT技术可把低档次的高金属和高硫含量的石油焦产率降低约70%。加氢后的LCO满足LTAG进料要求,可以生产轻芳烃(BTX)和高辛烷值汽油调合组分;DAO在比常规渣油加氢质量空速高1倍的情况下进行加氢,加氢后DAO的氢质量分数为12.25%~12.32%,残炭小于2.0%,金属(Ni+V)质量分数小于0.1μg/g,是优质催化裂化/催化裂解原料,可以多产低碳烯烃和高辛烷值汽油调合组分并大幅度降低过程剂耗。基于DOA和LCO混合油中高金属含量特点,研发了脱金属和容金属能力更强的RRC系列资源再造催化剂,运转后催化剂金属V和Ni沉积量高,是获取高价值V和Ni,尤其是V的宝贵资源。DAO加氢装置运转周期可以提高至4年,从根本上解决渣油加氢装置运转周期短的问题,同时后部渣油加氢脱硫催化剂可以再生,能够提高催化剂资源利用率。RIGHT技术能把减压渣油通过组分炼油技术更多地用于生产高价值低硫低金属含量石油焦和化工料,从而实现炼油领域高碳含量组分的低碳化和高值化利用。

Laparoscopic right radical hemicolectomy: Central vascular ligation and complete mesocolon excision vs D3 lymphadenectomy - How I do it?

In colon cancer surgery,ensuring the complete removal of the primary tumor and draining lymph nodes is crucial.Lymphatic drainage in the colon follows the vascular supply,typically progressing from pericolic to paraaortic lymph nodes.While NCCN guidelines recommend the removal of 10-12 lymph nodes for ade-quate oncological resection,achieving complete oncological resection involves more than just meeting these numerical targets.Various techniques have been developed and studied over time to attain optimal oncological outcomes.A key technique central to this goal is identifying the ileocolic vessels at their origin from the superior mesenteric vessels.Complete excision of the visceral and parietal mesocolon ensures the intact removal of the specimen,while D3 lymphade-nectomy targets all draining regional lymph nodes.Although these principles emphasize different aspects,they ultimately converge to achieve the same goal of complete oncological resection.This article aims to simplify the surgical steps that align with the principle of central vascular ligation and mesocolon mobilization while ensuring adequate D3 dissection.

Evaluation of Industrial IoT Service Providers with TOPSIS Based on Circular Intuitionistic Fuzzy Sets

Industrial Internet of Things(IIoT)service providers have become increasingly important in the manufacturing industry due to their ability to gather and process vast amounts of data from connected devices,enabling manufacturers to improve operational efficiency,reduce costs,and enhance product quality.These platforms provide manufacturers with real-time visibility into their production processes and supply chains,allowing them to optimize operations and make informed decisions.In addition,IIoT service providers can help manufacturers create new revenue streams through the development of innovative products and services and enable them to leverage the benefits of emerging technologies such as Artificial Intelligence(AI)and machine learning.Overall,the implementation of IIoT platforms in the manufacturing industry is crucial for companies seeking to remain competitive and meet the ever-increasing demands of customers in the digital age.In this study,the evaluation criteria to be considered in the selection of IIoT service provider in small andmedium-sized(SME)manufacturing enterprises will be determined and IIoT service providers alternatives will be evaluated using the technique for order preference by similarity to an ideal solution(TOPSIS)method based on circular intuitionistic fuzzy sets.Based on the assessments conducted in accordance with the literature review and expert consultations,a set of 8 selection criteria has been established.These criteria encompass industry expertise,customer support,flexibility and scalability,security,cost-effectiveness,reliability,data analytics,as well as compatibility and usability.Upon evaluating these criteria,it was observed that the security criterion holds the highest significance,succeeded by cost-effectiveness,data analytics,flexibility and scalability,reliability,and customer support criteria,in descending order of importance.Following the evaluation of seven distinct alternatives against these criteria,it was deduced that the A6 alternative,a German service provider,emerged as the most favorable option.The identical issue was addressed utilizing sensitivity analysis alongside various multi-criteria decision-making(MCDM)methods,and after comprehensive evaluation,the outcomes were assessed.Spearman’s correlation coefficient was computed to ascertain the association between the rankings derived from solving the problem using diverse MCDM methods.

Fuzzy Multi-Criteria Decision Support System for the Best Anti-Aging Treatment Selection Process through Normal Wiggly Hesitant Fuzzy Sets

This socialized environment among educated and developed people causes themto focusmore on their appearance and health,which turns them towards medical-related treatments,leading us to discuss anti-aging treatment methods for each age group,particularly for urban people who are interested in this.Some anti-aging therapies are used to address the alterations brought on by aging in human life without the need for surgery or negative effects.Five anti-aging therapies such as microdermabrasion or dermabrasion,laser resurfacing anti-aging skin treatments,chemical peels,dermal fillers for aged skin,and botox injections are considered in this study.Based on the criteria of safety risk,investment cost,customer happiness,and side effects,the optimal alternative is picked.As a result,a NormalWiggly Hesitant Pythagorean Fuzzy Set(NWHPFS)is constructed and used in Multi-Criteria Decision-Making(MCDM)using traditional wavy mathematical approaches.The entropy approach is utilized to determine weight values,and the Normal Wiggly Hesitant Pythagorean-VlseKriterijumska Optimizacija I Kompromisno Resenje(NWHPF-VIKOR)method is utilized to rank alternatives using MCDM methodologies.Sensitivity analysis and comparative analysis were performed to ensure the robustness and reliability of the proposed method.The smart final choice will undoubtedly assist Decision Makers(DM)in making the right judgments,and the MCDM approach will undoubtedly assist individuals in understanding the medicine.

The Theoretical Logic of the Right to Security

The growing significance of security issues has expanded the necessity and possibility of recognizing and achieving the goal of security from the perspective of human rights.Combined with socio-cultural and historical dynamics,human rights can be construed as the needs of people to which social authorities should and can respond,and their mechanism depends on“the alignment between people’s intrinsic needs and the social resources available.”Security,as a significant part of people’s intrinsic needs,should be supported by social resources;social authorities at all levels have the duty and potential to support people’s security needs.Thus,security has the socio-cultural basis to be considered as a branch of human rights.Once the human rights attribution of security has been established,further consideration is required for its place in the human rights spectrum.When analyzing the existing set of human rights,we can classify them based on the subject,the object,or the goal.The right to security is more appropriately classified within the dimension of goals,thereby being placed alongside the right to subsistence and the right to development.Integrating security into human rights can resolve the relationship between the right to security and other human rights using the theoretical framework of rights conflict,rights hierarchy,and rights system ranking,thereby avoiding the tendency to curb the security needs of countries and individuals by ideologizing human rights.

Fate of Right Coronary Artery Occlusion after a Surgically Repaired Aorto- Ventricular Tunnel in a Neonate

The aorto-ventricular tunnel is a rare congenital cardiac anomaly.We present a case of aorto-ventricular tunnel diagnosed via fetal echocardiography.Emergency surgery was performed on the 2nd day of life to close the tun-nel,located just in front of the right coronary ostium,due to the patient’s unstable health condition.The post-operative period revealed complete occlusion of the right coronary artery.Due to the patient’s stability,we opted not to reintervene on the right coronary artery.The patient fully recovered without the need for further coronary intervention.In cases of patients with an aorto-ventricular tunnel(AVT)and associated coronary lesions,it is crucial to exercise caution when intervening in the coronary arteries.

Quantum algorithm for minimum dominating set problem with circuit design

Using quantum algorithms to solve various problems has attracted widespread attention with the development of quantum computing.Researchers are particularly interested in using the acceleration properties of quantum algorithms to solve NP-complete problems.This paper focuses on the well-known NP-complete problem of finding the minimum dominating set in undirected graphs.To expedite the search process,a quantum algorithm employing Grover’s search is proposed.However,a challenge arises from the unknown number of solutions for the minimum dominating set,rendering direct usage of original Grover’s search impossible.Thus,a swap test method is introduced to ascertain the number of iterations required.The oracle,diffusion operators,and swap test are designed with achievable quantum gates.The query complexity is O(1.414^(n))and the space complexity is O(n).To validate the proposed approach,qiskit software package is employed to simulate the quantum circuit,yielding the anticipated results.

SET悬吊训练结合生物反馈技术在卒中患者下肢运动功能训练中的疗效观察

目的:探讨SET悬吊训练结合生物反馈技术在卒中患者下肢运动功能训练中的疗效。方法:选取佛山市南海区第五人民医院2022年1月—2023年12月期间收治的卒中下肢运动功能障碍患者72例为研究对象,分为2组,对照组(36例,实施SET悬吊训练)和实验组(36例,SET悬吊训练结合生物反馈技术),比较两组干预效果。结果:治疗后,实验组患者肌张力低于对照组;治疗后,实验组患者运动功能(FMA)评分、平衡功能(BBS)评分高于对照组(P<0.05)。结论:SET悬吊训练结合生物反馈技术对改善卒中患者下肢运动功能具有积极意义,有效改善患者的神经肌肉控制、降低肌张力、增强平衡和运动功能,进而提高其生活质量,值得推广和实施。

Arterial Hypertension-Related Factors within Custodial Settings of Southern Benin in 2023

Introduction: Hypertension, a non-communicable disease, is a major public health threat worldwide, accounting for a high level of morbidity and mortality. Although it has been extensively published among the general population, further research is needed to understand the reality of hypertension within the custodial setting. This study aimed to investigate the factors associated with arterial hypertension in custodial settings in southern Benin in 2023. Methods: This was a cross-sectional, descriptive, analytical study held in prisons in southern Benin from March to April 2023, involving inmates selected by two-stage random sampling. In the first stage, four prisons out of the six in the southern region of Benin were selected by simple random sampling. In the second stage, the prisoners were selected by systematic random sampling, with the sampling frame being the numbered list of eligible prisoners in each prison selected. Data collected by observation and questionnaire survey were analyzed using Stata 11 software. Hypertension was defined as systolic blood pressure ≥ 140 mmHg and diastolic blood pressure ≥ 90 mmHg. Overweight was defined by a body mass index (weight/height2 (kg/m2) ≥ 25. Factors associated with hypertension were identified by multiple logistic regression, at a 5% threshold of significance. Results: Altogether 336 inmates aged 37.55 ± 1.72 years were surveyed. The prevalence of hypertension in custodial settings in southern Benin in 2023 was 31.32% (95% CI [17.06;52.57]). Associated factors were inmate age (ORa = 3.36 95% CI: [1.94;5.85]) and abnormal waist circumference (ORa = 2.61 95% CI [1.27;5.40]). Conclusion: The prevalence of arterial hypertension in prisons of southern Benin (31.32%) is high when compared with the national average (25.9% (22.5-29.3)). The ministries of the Interior and Health need to collaborate to involve inmates in preventive strategies for non-communicable diseases, including hypertension.

Pragmatist View of Human Rights:Theoretical Explanations of China’s Human Rights Practice

The pragmatist view of human rights represents a the-oretical condensation of the Chinese practice in human rights devel-opment.In view of the problem of circular idling between rights and claims caused by the traditional view of human rights of focusing on contents and not valuing implementation,social segmentation caused by empty talks on interests and claims while ignoring social develop-ment,and the phenomenon of the issue of human rights completely becoming empty and useless political rhetoric,the pragmatic view of human rights,based on the fact that there is a gap between the claims and realization of human rights,emphasizes that instead of blindly ex-panding the types of rights in term of text,it is better to base on prac-tice and promote the maximum realization of existing rights through development.The pragmatist view of human rights attaches impor-tance to relevant economic,social and cultural basis to promote the realization of human rights,rather than only focusing on the claims themselves;it pays greater attention to enhancing the realization of rights,rather than the distribution of rights under the total limit;it ad-vocates more for cooperativism in the realization of rights,rather than confrontation.The pragmatic concept of human rights takes Marxism as its theoretical basis and the gene of practice and the dimension of development as its theoretical characteristics,and promotes the devel-opment of human rights through the realization of rights.

Incidence and Survivability of Acute Lymphocytic Leukemia Patients in the United States: Analysis of SEER Data Set from 2000-2019

The main goal of this research is to assess the impact of race, age at diagnosis, sex, and phenotype on the incidence and survivability of acute lymphocytic leukemia (ALL) among patients in the United States. By taking these factors into account, the study aims to explore how existing cancer registry data can aid in the early detection and effective treatment of ALL in patients. Our hypothesis was that statistically significant correlations exist between race, age at which patients were diagnosed, sex, and phenotype of the ALL patients, and their rate of incidence and survivability data were evaluated using SEER*Stat statistical software from National Cancer Institute. Analysis of the incidence data revealed that a higher prevalence of ALL was among the Caucasian population. The majority of ALL cases (59%) occurred in patients aged between 0 to 19 years at the time of diagnosis, and 56% of the affected individuals were male. The B-cell phenotype was predominantly associated with ALL cases (73%). When analyzing survivability data, it was observed that the 5-year survival rates slightly exceeded the 10-year survival rates for the respective demographics. Survivability rates of African Americans patients were the lowest compared to Caucasian, Asian, Pacific Islanders, Alaskan Native, Native Americans and others. Survivability rates progressively decreased for older patients. Moreover, this study investigated the typical treatment methods applied to ALL patients, mainly comprising chemotherapy, with occasional supplementation of radiation therapy as required. The study demonstrated the considerable efficacy of chemotherapy in enhancing patients’ chances of survival, while those who remained untreated faced a less favorable prognosis from the disease. Although a significant amount of data and information exists, this study can help doctors in the future by diagnosing patients with certain characteristics. It will further assist the health care professionals in screening potential patients and early detection of cases. This could also save the lives of elderly patients who have a higher mortality rate from this disease.

Venopulmonary ECMO Improved Hypoxemia and Supported the Right Ventricle in a Patient with Decompensated Eisenmenger Syndrome

Mechanical circulatory and/or respiratory assistance with extracorporeal membrane oxygenation (ECMO) has become a standard of care for patients with circulatory (venoarterial) and/or respiratory (venovenous) failure refractory to standard therapies. Adult patients with congenital heart disease are an increasingly recognized and growing population and include various groups, such as undiagnosed cases in childhood and palliated and/or corrected cases, which require subsequent care because of residual lesions, cardiac arrest/insufficiency, and arrhythmias, among other conditions. In addition, these patients are prone to developing pathologies that are typical of adulthood with a generally increased risk of morbidity and mortality because of their low reserves and organic damage associated with the underlying heart disease, which makes them candidates for ECMO. These patients represent an additional challenge in this therapy because malformations and the presence of a shunt can generally affect the usual cannulation methods and hemodynamic and oximetry monitoring. Thus, the configuration decision must be made on a case-by-case basis. Here, we present a cannulation method, venopulmonary artery ECMO, which provides hemodynamic and respiratory support, and may be ideal for patients with shunts and/or right ventricular dysfunction. To our knowledge, this is the first report of this configuration in patients with congenital heart diseases.

Development of a High Early Strength Non-fuorine and Non-alkaline Flash Setting Admixture and Flash Mechanism

To solve the problems of high rebound rate and strength reversion of shotcrete,a non-fluorine and non-alkaline liquid flash setting admixture(FSN)with low rebound and high early strength was synthesized under 60-65℃water bath environment through orthogonal test design and taking setting time and compressive strength as indicators.The experimental results show that the optimum mass ratio of FSN is aluminum sulfate:diethanolamine:triethanolamine:pseudo-boehmite:lithium carbonate:water=57%:8%:0.05%:2%:2%:31%.When FSN is added with 7%of the mass of portland cement,the cement paste can be initially set in 3 min and finally set in 5 min.The compressive strength of mortar is 1.2 MPa at 6 h,18.0 MPa at 1 d,and more than 100%at 28 days;The microscopic analysis shows that the rapid release of Li^(+),NH^(4+),and CO_(3)^(2-)ions by FSN in the paste solution effectively shortens the induction period of high C_(3)S content in Portland cement,directly forms early coagulation AFt crystals in FSN and CH dominated by Al_(2)(SO_(4))_(3),and forms a large number of C-S-H gels in the later stage,so that the cement can quickly coagulate and harden,and the strength in the later stage is not retracted.