Based on the continuously stratified quasi-geostrophic vorticity equation. the present paper analyses the instabilityof three-dimensional shear waves.The cause that most shear waves occur on the shelfside of strong cu...Based on the continuously stratified quasi-geostrophic vorticity equation. the present paper analyses the instabilityof three-dimensional shear waves.The cause that most shear waves occur on the shelfside of strong current near the west boundaries of the oceans is presented. The growth rate of small perturbations relies on the stratification charctters, and a maximum value of growth rate exists for certain stratification.展开更多
Starting from vorticity equation, the triggering mechanism and amplitude decay of shear waves in the ocean are discussed in this paper. The theoretical analysis indicates that by the action of stripped external force ...Starting from vorticity equation, the triggering mechanism and amplitude decay of shear waves in the ocean are discussed in this paper. The theoretical analysis indicates that by the action of stripped external force (for examples, the sudden setting of stripped wind, moving stripped wind, etc. ), shear waves can be triggered. This is qualitatively consistent with satellite observations. The amplitude decay process of shear waves by the action of side friction is also discussed in the paper. The theoretical model is quantitatively consistent with satellite observations.展开更多
- Starting from satellite remote sensing data, the dynamical processes of shear waves occurring at the boundary between the western boundary current and the shelf slope water are studied and dynamically analyzed in th...- Starting from satellite remote sensing data, the dynamical processes of shear waves occurring at the boundary between the western boundary current and the shelf slope water are studied and dynamically analyzed in this study. The average wavelength is 75 km, and the average amplitude (from crest to trough )17 km. the average phase speed 100 cms-1 for the shear waves along the north wall of the Gulf Stream to the east of Cape Hatteras measured from NOAA satellite IR (infrared ) images. The average wavelength of shear waves along the north wall of the Kuroshio Current is 57 km, and the average amplitude 17 km. For the shear waves occurring along the west wall of the Gulf Stream to the south of Cape Hatteras, the average wavelength is 131 km, and the average amplitude 33 km measured from Seasat SAR (synthetic aperture radar )images. The time for one cycle of shear wave event is about one week.In order to explore the dynamical mechanisms of shear waves, we solved the vorticity equation for a stratified fluid, and obtained an analytical expression of dispersion relation of shear waves. The results indicated that there was a parabolic relation between the phase speed and the wavelength of shear waves, and the mean flow field was an important factor in the dispersion relation. The latter point means that the horizontal tangent variation of velocity is a basic condition for shear wave occurrence. Theoretical analyses are confirmed by satellite remote sensing data.展开更多
In this paper, the scattering of harmonic antiplane shear waves bytwo finite cracks is studied using the non-local theory. The Fouriertransform is applied and a mixed boundary value prob- lem isformulated. Then a set ...In this paper, the scattering of harmonic antiplane shear waves bytwo finite cracks is studied using the non-local theory. The Fouriertransform is applied and a mixed boundary value prob- lem isformulated. Then a set of triple integral equations is solved using anew method, namely Schimidt's method. This method is more exact andmore reasonable than Erigen's for solving this Kind of problem. Theresult of the stress near the crack tip was obtained. Contrary to theclassical elas- Ticity solution, it is found that no stresssingularity is present at the crack tip, which can explain theProblem of macroscopic and microscopic mechanics.展开更多
This paper studies the propagation of horizontally polarized shear waves in an internal magnetoelastic monoclinic stratum with irregularity in lower interface. The stratum is sandwiched between two magnetoelastic mono...This paper studies the propagation of horizontally polarized shear waves in an internal magnetoelastic monoclinic stratum with irregularity in lower interface. The stratum is sandwiched between two magnetoelastic monoclinic semi-infinite media. Dispersion equation is obtained in a closed form. In the absence of magnetic field and irregularity of the medium, the dispersion equation agrees with the equation of classical case in three layered media. The effects of magnetic field and size of irregularity on the phase velocity are depicted by means of graphs.展开更多
Based on the quasi-geostrophic vorticity equation, the present peper simulates the water mxing process in the formation Of ocean shear waves using large eddy simulation methods. From Lagrangian tracing, we study the o...Based on the quasi-geostrophic vorticity equation, the present peper simulates the water mxing process in the formation Of ocean shear waves using large eddy simulation methods. From Lagrangian tracing, we study the ocean shear wave's changing from wave character to vortex character. The distance between tracer groups increases near the ocean shear wave area, and decreases between ocean shear waves. The tracers that are uniformally distributed in space do not retain the uniform character in the mixing process. The frequency shift of the perturbation waves is caused by their nonlinear interaction. The wave number ratio and phase lag of the initial perturbation waves affect the mixing process, but the results show little difference. The increase of the viscosity coefficient will restrain the mixing process.展开更多
Elastography can be used as a diagnostic method for quantitative characterization of tissue hardness information and thus,differential changes in pathophysiological states of tissues.In this study,we propose a new met...Elastography can be used as a diagnostic method for quantitative characterization of tissue hardness information and thus,differential changes in pathophysiological states of tissues.In this study,we propose a new method for shear wave elastography(SWE)based on laser-excited shear wave,called photoacoustic shear wave elastography(PASWE),which combines photoacoustic(PA)technology with ultrafast ultrasound imaging.By using a focused laser to excite shear waves and ultrafast ultrasonic imaging for detection,high-frequency excitation of shear waves and noncontact elastic imaging can be realized.The laser can stimulate the tissue with the light absorption characteristic to produce the thermal expansion,thus producing the shear wave.The frequency of shear wave induced by laser is higher and the frequency band is wider.By tracking the propagation of shear wave,Young’s modulus of tissue is reconstructed in the whole shear wave propagation region to further evaluate the elastic information of tissue.The feasibility of the method is verified by experiments.Compared with the experimental results of supersonic shear imaging(SSI),it is proved that the method can be used for quantitative elastic imaging of the phantoms.In addition,compared with the SSI method,this method can realize the noncontact excitation of the shear wave,and the frequency of the shear wave excited by the laser is higher than that of the acoustic radiation force(ARF),so the spatial resolution is higher.Compared to the traditional PA elastic imaging method,this method can obtain a larger imaging depth under the premise of ensuring the imaging resolution,and it has potential application value in the clinical diagnosis of diseases requiring noncontact quantitative elasticity.展开更多
BACKGROUND Integrating conventional ultrasound features with 2D shear wave elastography(2D-SWE)can potentially enhance preoperative hepatocellular carcinoma(HCC)predictions.AIM To develop a 2D-SWE-based predictive mod...BACKGROUND Integrating conventional ultrasound features with 2D shear wave elastography(2D-SWE)can potentially enhance preoperative hepatocellular carcinoma(HCC)predictions.AIM To develop a 2D-SWE-based predictive model for preoperative identification of HCC.METHODS A retrospective analysis of 884 patients who underwent liver resection and pathology evaluation from February 2021 to August 2023 was conducted at the Oriental Hepatobiliary Surgery Hospital.The patients were divided into the modeling group(n=720)and the control group(n=164).The study included conventional ultrasound,2D-SWE,and preoperative laboratory tests.Multiple logistic regression was used to identify independent predictive factors for RESULTS In the modeling group analysis,maximal elasticity(Emax)of tumors and their peripheries,platelet count,cirrhosis,and blood flow were independent risk indicators for malignancies.These factors yielded an area under the curve of 0.77(95%confidence interval:0.73-0.81)with 84%sensitivity and 61%specificity.The model demonstrated good calibration in both the construction and validation cohorts,as shown by the calibration graph and Hosmer-Lemeshow test(P=0.683 and P=0.658,respectively).Additionally,the mean elasticity(Emean)of the tumor periphery was identified as a risk factor for microvascular invasion(MVI)in malignant liver tumors(P=0.003).Patients receiving antiviral treatment differed significantly in platelet count(P=0.002),Emax of tumors(P=0.033),Emean of tumors(P=0.042),Emax at tumor periphery(P<0.001),and Emean at tumor periphery(P=0.003).CONCLUSION 2D-SWE’s hardness value serves as a valuable marker for enhancing the preoperative diagnosis of malignant liver lesions,correlating significantly with MVI and antiviral treatment efficacy.展开更多
Shear wave splitting(SWS)is regarded as the most effective geophysical method to delineate mantle flow fields by detecting seismic azimuthal anisotropy in the earth's upper mantle,especially in tectonically active...Shear wave splitting(SWS)is regarded as the most effective geophysical method to delineate mantle flow fields by detecting seismic azimuthal anisotropy in the earth's upper mantle,especially in tectonically active regions such as subduction zones.The Aleutian-Alaska subduction zone has a convergence rate of approximately 50 mm/yr,with a trench length reaching nearly 2800 km.Such a long subduction zone has led to intensive continental deformation and numerous strong earthquakes in southern and central Alaska,while northern Alaska is relatively inactive.The sharp contrast makes Alaska a favorable locale to investigate the impact of subduction on mantle dynamics.Moreover,the uniqueness of this subduction zone,including the unusual subducting type,varying slab geometry,and atypical magmatic activity and composition,has intrigued the curiosity of many geoscientists.To identify different sources of seismic anisotropy beneath the Alaska region and probe the influence of a geometrically varying subducting slab on mantle dynamics,extensive SWS analyses have been conducted in the past decades.However,the insufficient station and azimuthal coverage,especially in early studies,not only led to some conflicting results but also strongly limited the in-depth investigation of layered anisotropy and the estimation of anisotropy depth.With the completion of the Transportable Array project in Alaska,recent studies have revealed more detailed mantle structures and characteristics based on the dense station coverage and newly collected massive seismic data.In this study,we review significant regional-and continental-scale SWS studies in the Alaska region and conclude the mantle flow fields therein,to understand how a geometrically varying subducting slab alters the regional mantle dynamics.The summarized mantle flow mechanisms are believed to be conducive to the understanding of seismic anisotropy patterns in other subduction zones with a complicated tectonic setting.展开更多
BACKGROUND Real-time shear wave elastography(SWE)is a non-invasive imaging technique used to measure tissue stiffness by generating and tracking shear waves in real time.This advanced ultrasound-based method provides ...BACKGROUND Real-time shear wave elastography(SWE)is a non-invasive imaging technique used to measure tissue stiffness by generating and tracking shear waves in real time.This advanced ultrasound-based method provides quantitative information regarding tissue elasticity,offering valuable insights into the mechanical properties of biological tissues.However,the application of real-time SWE in the musculoskeletal system and sports medicine has not been extensively studied.AIM To explore the practical value of real-time SWE for assessing Achilles tendon hardness in older adults.METHODS A total of 60 participants were enrolled in the present study,and differences in the elastic moduli of the bilateral Achilles tendons were compared among the following categories:(1)Age:55-60,60-65,and 65-70-years-old;(2)Sex:Male and female;(3)Laterality:Left and right sides;(4)Tendon state:Relaxed and tense state;and(5)Tendon segment:Proximal,middle,and distal.RESULTS There were no significant differences in the elastic moduli of the bilateral Achilles tendons when comparing by age or sex(P>0.05).There were,however,significant differences when comparing by tendon side,state,or segment(P<0.05).CONCLUSION Real-time SWE plays a significant role compared to other examination methods in the evaluation of Achilles tendon hardness in older adults.展开更多
BACKGROUND Detection of early chronic changes in the kidney allograft is important for timely intervention and long-term survival.Conventional and novel ultrasound-based investigations are being increasingly used for ...BACKGROUND Detection of early chronic changes in the kidney allograft is important for timely intervention and long-term survival.Conventional and novel ultrasound-based investigations are being increasingly used for this purpose with variable results.AIM To compare the diagnostic performance of resistive index(RI)and shear wave elastography(SWE)in the diagnosis of chronic fibrosing changes of kidney allograft with histopathological results.METHODS This is a cross-sectional and comparative study.A total of 154 kidney transplant recipients were included in this study,which was conducted at the Departments of Transplantation and Radiology,Sindh Institute of Urology and Transplantation,Karachi,Pakistan,from August 2022 to February 2023.All consecutive patients with increased serum creatinine levels and reduced glomerular filtration rate(GFR)after three months of transplantation were enrolled in this study.SWE and RI were performed and the findings of these were evaluated against the kidney allograft biopsy results to determine their diagnostic utility.RESULTS The mean age of all patients was 35.32±11.08 years.Among these,126(81.8%)were males and 28(18.2%)were females.The mean serum creatinine in all patients was 2.86±1.68 mg/dL and the mean estimated GFR was 35.38±17.27 mL/min/1.73 m2.Kidney allograft biopsy results showed chronic changes in 55(37.66%)biopsies.The sensitivity,specificity,positive predictive value(PPV),and negative predictive value(NPV)of SWE for the detection of chronic allograft damage were 93.10%,96.87%%,94.73%,and 95.87%,respectively,and the diagnostic accuracy was 95.45%.For RI,the sensitivity,specificity,PPV,and NPV were 76.92%,83.33%,70.17%,and 87.62%,respectively,and the diagnostic accuracy was 81.16%.CONCLUSION The results from this study show that SWE is more sensitive and specific as compared to RI in the evaluation of chronic allograft damage.It can be of great help during the routine follow-up of kidney transplant recipients for screening and early detection of chronic changes and selecting patients for allograft biopsy.展开更多
The ability to reliably detect coronary artery disease based on the acousticnoises produced by a stenosis can provide a simple, non-invasive technique for diagnosis.Current research exploits the shear wave fields in b...The ability to reliably detect coronary artery disease based on the acousticnoises produced by a stenosis can provide a simple, non-invasive technique for diagnosis.Current research exploits the shear wave fields in body tissue to detect andanalyze coronary stenoses. The methods and ideas outlined in earlier efforts [6] includinga mathematical model utilizing an internal strain variable approximation tothe quasi-linear viscoelastic constitutive equation proposed by Fung in [19] is extendedhere. As an initial investigation, a homogeneous two-dimensional viscoelastic geometryis considered. Being uniform in θ, this geometry behaves as a one dimensionalmodel, and the results generated from it are compared to the one dimensional resultsfrom [6]. To allow for different assumptions on the elastic response, several variationsof the model are considered. A statistical significance test is employed to determine ifthe more complex models are significant improvements. After calibrating the modelwith a comparison to previous findings, more complicated geometries are considered.Simulations involving a heterogeneous geometrywith a uniformring running throughthe original medium, a θ-dependent model which considers a rigid partial occlusionformed along the inner radius of the geometry, and a model which combines the ringand occlusion are presented.展开更多
Two-dimensional scalar equation for the displacement of steady cross-plane shear (SH) waves in homogeneous and transversely isotropic media like unidirectional fibrous com-posites is given. Then, thrbugh a simple coor...Two-dimensional scalar equation for the displacement of steady cross-plane shear (SH) waves in homogeneous and transversely isotropic media like unidirectional fibrous com-posites is given. Then, thrbugh a simple coordinate system transform, the scalar equation is standardized into a Helmholtz equation. Corresponding integral equations are derived for the scattering problems and boundary element method (BEM) is used to calculate the scattered fields of arbitrarily shaped obstacles with both soft and rigid boudary conditions numerically.A discussion is given on the numerical results which is mainly focused on the influence of the a-nisotropy of the media to the directivity of the scattered fields by circular cylindrical voids.展开更多
Cyclic freezing-thawing can lead to fracture development in coal,affecting its mechanical and consumer properties.To study crack formations in coal,an ultrasonic sounding method using shear polarized waves was propose...Cyclic freezing-thawing can lead to fracture development in coal,affecting its mechanical and consumer properties.To study crack formations in coal,an ultrasonic sounding method using shear polarized waves was proposed.Samples of three coal types(anthracite,lignite and hard coal)were tested.The research results show that,in contrast to the shear wave velocity,the shear wave amplitude is extremely sensitive to the formation of new cracks at the early stages of cyclic freezing-thawing.Tests also show an inverse correlation between coal compressive strength and its tendency to form cracks under temperature impacts;shear wave attenuation increases more sharply in high-rank coals after the first freezing cycle.Spectral analysis of the received signals also confirmed significant crack formation in anthracite after the first freeze-thaw cycle.The initial anisotropy was determined,and its decrease with an increase in the number of freeze-thaw cycles was shown.The data obtained forms an experimental basis for the development of new approaches to preserve coal consumer properties during storage and transportation under severe natural and climatic conditions.展开更多
The Shimian area of Sichuan sits at the junction of the Bayan Har block.Sichuan-Yunnan rhombic block,and Yangtze block,where several faults intersect.This region features intense tectonic activity and frequent earthqu...The Shimian area of Sichuan sits at the junction of the Bayan Har block.Sichuan-Yunnan rhombic block,and Yangtze block,where several faults intersect.This region features intense tectonic activity and frequent earthquakes.In this study,we used local seismic waveform data recorded using dense arrays deployed in the Shimian area to obtain the shear wave splitting parameters at 55 seismic stations and thereby determine the crustal anisotropic characteristics of the region.We then analyzed the crustal stress pattern and tectonic setting and explored their relationship in the study area.Although some stations returned a polarization direction of NNW-SSE.a dominant polarization direction of NW-SE was obtained for the fast shear wave at most seismic stations in the study area.The polarization directions of the fast shear wave were highly consistent throughout the study-area.This orientation was in accordance with the direction of the regional principal compressive stress and parallel to the trend of the Xianshuihe and Daliangshan faults.The distribution of crustal anisotropy in this area was affected by the regional tectonic stress field and the fault structures.The mean delay time between fast and slow shear waves was 3.83 ms/km.slightly greater than the values obtained in other regions of Sichuan.This indicates that the crustal media in our study area had a high anisotropic strength and also reveals the influence of tectonic complexity resulting from the intersection of multiple faults on the strength of seismic anisotropy.展开更多
The discrete element method(DEM)is a capable tool used to simulate shear wave propagation in granular assemblies for many years.Researchers have studied assembly shapes such as rectangles(in 2D simulations)or cylinder...The discrete element method(DEM)is a capable tool used to simulate shear wave propagation in granular assemblies for many years.Researchers have studied assembly shapes such as rectangles(in 2D simulations)or cylinders and cubes(in 3D simulations).This paper aimed to qualify the effect of assembly shape on the shear wave propagation and maximum amplification in the vertical plane(horizontal and vertical directions)caused by this propagation.To this end,shear wave propagations in different assembly shapes such as rectangle,trapezium,and triangle with rigid boundary conditions were simulated.A sine wave pulse was applied with a point source by moving a particle as the transmitter particle.To evaluate the shear wave velocity of the assemblies,the transmitter and receiver particles were simulated.All the simulations were performed with 2D DEM which is a useful tool to determine the amount and location of the maximum amplification factor of the assembly in both horizontal and vertical directions.An advantage of this study was assessing the effect of parameters such as input wave frequency,assembly height,shape,and aspect ratios on the amplification of the input waves.展开更多
BACKGROUND The treatment of hepatitis C with direct-acting antiviral agents(DAAs)produces a high rate of sustained virological response(SVR)with fewer adverse events than interferon(IFN)therapy with a similar effect i...BACKGROUND The treatment of hepatitis C with direct-acting antiviral agents(DAAs)produces a high rate of sustained virological response(SVR)with fewer adverse events than interferon(IFN)therapy with a similar effect in inhibiting carcinogenesis as IFN therapy.The age-male-albumin-bilirubin-platelets(aMAP)score is useful for stratifying the risk of hepatocellular carcinoma in chronic hepatitis patients,and the velocity of shear waves(Vs)measured by shear wave elastography has also been shown to be useful for diagnosing the level of fibrotic progression in hepatitis C and predicting carcinogenic risk.Combining these two may improve the prediction of carcinogenic risk.AIM To determine whether combining the aMAP score with Vs improves carcinogenic risk stratification in medium-to-high-risk hepatitis C patients.METHODS This retrospective,observational study involved hepatitis C patients treated with DAAs who achieved SVR.Vs was measured before treatment(baseline),at the end of treatment(EOT),and 12 wk(follow-up 12)and 24 wk(follow-up 24)after treatment.The patients were followed for at least six months after EOT to determine whether cancer developed.Multiple regression analysis was used to identify factors contributing to hepatic carcinogenesis.The diagnostic performances of clinical parameters for predicting the presence of hepatocellular carcinoma were evaluated using receiver-operating characteristic(ROC)curve analyses.RESULTS A total of 279 patients(mean age 65.9 years,118 males,161 females)were included in the analysis.Multiple regression analysis was performed with carcinogenesis as the target variable and alanine aminotransferase,platelets,α-fetoprotein,Vs,and the Fib-4 index as explanatory variables;only Vs was found to be significant(P=0.0296).The cut-off value for Vs for liver carcinogenesis calculated using the ROC curve was 1.53 m/s.Carcinoma developed in 2.0%(3/151)of those with Vs<1.53 m/s and in 10.5%(9/86)of those with Vs≥1.53 m/s.CONCLUSION In hepatitis C patients after SVR,combining the aMAP score and Vs to stratify the risk of carcinogenesis is more efficient than uniform surveillance of all patients.展开更多
Characterizing the gap eigenmode of shear Alfv′en waves(SAWs) and its interaction with energetic ions is important to the success of magnetically confined fusion. Previous studies have reported an experimental observ...Characterizing the gap eigenmode of shear Alfv′en waves(SAWs) and its interaction with energetic ions is important to the success of magnetically confined fusion. Previous studies have reported an experimental observation of the spectral gap of SAW on the on Large Plasma Device(LAPD)(Zhang et al. 2008 Phys. Plasmas 15 012103), a linear large plasma device(Gekelman et al. 1991 Rev. Sci. Instrum. 62 2875) possessing easier diagnostic access and lower cost compared with traditional fusion devices, and analytical theory and numerical gap eigenmode using ideal conditions(Chang 2014 Ph.D Thesis at Australian National University). To guide experimental implementation, the present work models the gap eigenmode of SAWs using exact LAPD parameters. A full picture of the wave field for previous experiment reveals that the previously observed spectral gap is not global but an axially local result. To form a global spectral gap, the number of magnetic mirrors has to be increased and stronger static magnetic field makes it clearer. Such a spectral gap is obtained for the magnetic field of B0(z) = 1.2 + 0.6 cos[2π(z-33.68)/3.63] with 7.74-m magnetic beach. By introducing two types of local defects(corresponding to Eθ(z0) = 0 and E’θ(z0) = 0 respectively), odd-parity and even-parity discrete eigenmodes are formed clearly inside the gap. The strength of these gap eigenmodes decreases significantly with collision frequency, which is consistent with previous studies. Parameter scans show that these gap eigenmodes can be even formed successfully for the field strength of B0(z) = 0.2 + 0.1 cos[2π(z-33.68)/3.63] and with only four magnetic mirrors, which are achievable by the LAPD at its present status. This work can serve as a strong motivation and direct reference for the experimental implementation of the gap eigenmode of SAWs on the LAPD and other linear plasma devices.展开更多
BACKGROUND Primary breast diffuse large B-cell lymphoma(PB-DLBCL)is a rare subtype of non-Hodgkin lymphoma that accounts for<3%of extranodal lymphomas and 1%of breast tumors.Its diagnosis and management are challen...BACKGROUND Primary breast diffuse large B-cell lymphoma(PB-DLBCL)is a rare subtype of non-Hodgkin lymphoma that accounts for<3%of extranodal lymphomas and 1%of breast tumors.Its diagnosis and management are challenging because of its rarity,heterogeneity,and aggressive behavior.Conventional ultrasound(US)is the first-line imaging modality for breast lesions;however,it has limited specificity and accuracy for PB-DLBCL.Shear wave elastography(SWE)is a novel US technique that measures tissue stiffness and may reflect the histological characteristics and biological behavior of breast lesions.AIM To compare the conventional US and SWE features of PB-DLBCL and evaluate their diagnostic performance and prognostic value.METHODS We retrospectively reviewed the clinical data and US images of 32 patients with pathologically confirmed PB-DLBCL who underwent conventional US and SWE before treatment.We analyzed conventional US features(shape,margin,orientation,echo,posterior acoustic features,calcification,and vascularity)and SWE features(mean elasticity value,standard deviation,minimum elasticity value,maximum elasticity value,and lesion-to-fat ratio)of the PB-DLBCL lesions.Using receiver operating characteristic curve analysis,we determined the optimal cutoff values and diagnostic performance of conventional US and SWE features.We also performed a survival analysis to assess the prognostic value of conventional US and SWE features.RESULTS The results showed that the PB-DLBCL lesions were mostly irregular in shape(84.4%),microlobulated or spiculated in margins(75%),parallel in orientation(65.6%),hypoechoic in echo(87.5%),and had posterior acoustic enhancement(65.6%).Calcification was rare(6.3%)and vascularity was variable(31.3%avascular,37.5%hypovascular,and 31.3%hypervascular).The mean elasticity value of PB-DLBCL lesions was significantly higher than that of benign breast lesions(113.4±46.9 kPa vs 27.8±16.4 kPa,P<0.001).The optimal cutoff value of the mean elasticity for distinguishing PB-DLBCL from benign breast lesions was 54.5 kPa,with a sensitivity of 93.8%,specificity of 92.9%,positive predictive value of 93.8%,negative predictive value of 92.9%,and accuracy of 93.3%.The mean elasticity value was also significantly correlated with Ki-67 expression level(r=0.612,P<0.001),which is a marker of tumor proliferation and aggressiveness.Survival analysis showed that patients with higher mean elasticity values(>54.5 kPa)had worse overall survival(OS)and progression-free survival(PFS)than those with lower mean elasticity values(<54.5 kPa)(P=0.038 for OS and P=0.027 for PFS).CONCLUSION Conventional US and SWE provide useful information for diagnosing and forecasting PB-DLBCL.SWE excels in distinguishing PB-DLBCL from benign breast lesions,reflects tumor proliferation and aggressiveness,and improves disease management.展开更多
The vibrator plate is the link between the vibroseis vehicle and the earth,as well as the core com-ponent of the vibrator vehicle.In this paper,the coupling effect between the vibrator plate and the earth is an-alyzed...The vibrator plate is the link between the vibroseis vehicle and the earth,as well as the core com-ponent of the vibrator vehicle.In this paper,the coupling effect between the vibrator plate and the earth is an-alyzed from two aspects of reaction tooth arrangement and reaction tooth conical angle,and three groups of experimental models are optimized and designed.The model construction and numerical analysis of the shear wave vibroseis vibrator plate are carried out with ANSYS software.The motion law between the vibration plate and the earth at work was studied,the strain energy of the three experimental models in operation,the maximum displacement of particle at the same position and other reference indices were compared and ana-lyzed,with 28 conical reaction teeth were arranged on both sides.The coupling effect between the vibration plate and the earth was best when the tooth angle was 60°.Compared with the toothless vibration plate,the energy efficiency is improved by about 20%,and the coupling effect between the vibrator plate and the earth is effectively enhanced.It is found that the coupling effect is enhanced through increasing the number of reac-tion teeth of the vibration plate by increasing the coupling area between the vibration plate and the earth.展开更多
文摘Based on the continuously stratified quasi-geostrophic vorticity equation. the present paper analyses the instabilityof three-dimensional shear waves.The cause that most shear waves occur on the shelfside of strong current near the west boundaries of the oceans is presented. The growth rate of small perturbations relies on the stratification charctters, and a maximum value of growth rate exists for certain stratification.
文摘Starting from vorticity equation, the triggering mechanism and amplitude decay of shear waves in the ocean are discussed in this paper. The theoretical analysis indicates that by the action of stripped external force (for examples, the sudden setting of stripped wind, moving stripped wind, etc. ), shear waves can be triggered. This is qualitatively consistent with satellite observations. The amplitude decay process of shear waves by the action of side friction is also discussed in the paper. The theoretical model is quantitatively consistent with satellite observations.
文摘- Starting from satellite remote sensing data, the dynamical processes of shear waves occurring at the boundary between the western boundary current and the shelf slope water are studied and dynamically analyzed in this study. The average wavelength is 75 km, and the average amplitude (from crest to trough )17 km. the average phase speed 100 cms-1 for the shear waves along the north wall of the Gulf Stream to the east of Cape Hatteras measured from NOAA satellite IR (infrared ) images. The average wavelength of shear waves along the north wall of the Kuroshio Current is 57 km, and the average amplitude 17 km. For the shear waves occurring along the west wall of the Gulf Stream to the south of Cape Hatteras, the average wavelength is 131 km, and the average amplitude 33 km measured from Seasat SAR (synthetic aperture radar )images. The time for one cycle of shear wave event is about one week.In order to explore the dynamical mechanisms of shear waves, we solved the vorticity equation for a stratified fluid, and obtained an analytical expression of dispersion relation of shear waves. The results indicated that there was a parabolic relation between the phase speed and the wavelength of shear waves, and the mean flow field was an important factor in the dispersion relation. The latter point means that the horizontal tangent variation of velocity is a basic condition for shear wave occurrence. Theoretical analyses are confirmed by satellite remote sensing data.
文摘In this paper, the scattering of harmonic antiplane shear waves bytwo finite cracks is studied using the non-local theory. The Fouriertransform is applied and a mixed boundary value prob- lem isformulated. Then a set of triple integral equations is solved using anew method, namely Schimidt's method. This method is more exact andmore reasonable than Erigen's for solving this Kind of problem. Theresult of the stress near the crack tip was obtained. Contrary to theclassical elas- Ticity solution, it is found that no stresssingularity is present at the crack tip, which can explain theProblem of macroscopic and microscopic mechanics.
基金supported by the Department of Science and Technology of New Delhi(No.SR/S4/MS:436/07)
文摘This paper studies the propagation of horizontally polarized shear waves in an internal magnetoelastic monoclinic stratum with irregularity in lower interface. The stratum is sandwiched between two magnetoelastic monoclinic semi-infinite media. Dispersion equation is obtained in a closed form. In the absence of magnetic field and irregularity of the medium, the dispersion equation agrees with the equation of classical case in three layered media. The effects of magnetic field and size of irregularity on the phase velocity are depicted by means of graphs.
文摘Based on the quasi-geostrophic vorticity equation, the present peper simulates the water mxing process in the formation Of ocean shear waves using large eddy simulation methods. From Lagrangian tracing, we study the ocean shear wave's changing from wave character to vortex character. The distance between tracer groups increases near the ocean shear wave area, and decreases between ocean shear waves. The tracers that are uniformally distributed in space do not retain the uniform character in the mixing process. The frequency shift of the perturbation waves is caused by their nonlinear interaction. The wave number ratio and phase lag of the initial perturbation waves affect the mixing process, but the results show little difference. The increase of the viscosity coefficient will restrain the mixing process.
基金supported by the National Key R&D Program of China(Grant No.2022YFC2402400)the National Natural Science Foundation of China(Grant No.62275062)and Guangdong Provincial Key Laboratory of Biomedical Optical Imaging Technology(Grant No.2020B121201010-4).
文摘Elastography can be used as a diagnostic method for quantitative characterization of tissue hardness information and thus,differential changes in pathophysiological states of tissues.In this study,we propose a new method for shear wave elastography(SWE)based on laser-excited shear wave,called photoacoustic shear wave elastography(PASWE),which combines photoacoustic(PA)technology with ultrafast ultrasound imaging.By using a focused laser to excite shear waves and ultrafast ultrasonic imaging for detection,high-frequency excitation of shear waves and noncontact elastic imaging can be realized.The laser can stimulate the tissue with the light absorption characteristic to produce the thermal expansion,thus producing the shear wave.The frequency of shear wave induced by laser is higher and the frequency band is wider.By tracking the propagation of shear wave,Young’s modulus of tissue is reconstructed in the whole shear wave propagation region to further evaluate the elastic information of tissue.The feasibility of the method is verified by experiments.Compared with the experimental results of supersonic shear imaging(SSI),it is proved that the method can be used for quantitative elastic imaging of the phantoms.In addition,compared with the SSI method,this method can realize the noncontact excitation of the shear wave,and the frequency of the shear wave excited by the laser is higher than that of the acoustic radiation force(ARF),so the spatial resolution is higher.Compared to the traditional PA elastic imaging method,this method can obtain a larger imaging depth under the premise of ensuring the imaging resolution,and it has potential application value in the clinical diagnosis of diseases requiring noncontact quantitative elasticity.
基金Supported by the National Natural Science Foundation of China Youth Training Project,No.2021GZR003and Medical-engineering Interdisciplinary Research Youth Training Project,No.2022YGJC001.
文摘BACKGROUND Integrating conventional ultrasound features with 2D shear wave elastography(2D-SWE)can potentially enhance preoperative hepatocellular carcinoma(HCC)predictions.AIM To develop a 2D-SWE-based predictive model for preoperative identification of HCC.METHODS A retrospective analysis of 884 patients who underwent liver resection and pathology evaluation from February 2021 to August 2023 was conducted at the Oriental Hepatobiliary Surgery Hospital.The patients were divided into the modeling group(n=720)and the control group(n=164).The study included conventional ultrasound,2D-SWE,and preoperative laboratory tests.Multiple logistic regression was used to identify independent predictive factors for RESULTS In the modeling group analysis,maximal elasticity(Emax)of tumors and their peripheries,platelet count,cirrhosis,and blood flow were independent risk indicators for malignancies.These factors yielded an area under the curve of 0.77(95%confidence interval:0.73-0.81)with 84%sensitivity and 61%specificity.The model demonstrated good calibration in both the construction and validation cohorts,as shown by the calibration graph and Hosmer-Lemeshow test(P=0.683 and P=0.658,respectively).Additionally,the mean elasticity(Emean)of the tumor periphery was identified as a risk factor for microvascular invasion(MVI)in malignant liver tumors(P=0.003).Patients receiving antiviral treatment differed significantly in platelet count(P=0.002),Emax of tumors(P=0.033),Emean of tumors(P=0.042),Emax at tumor periphery(P<0.001),and Emean at tumor periphery(P=0.003).CONCLUSION 2D-SWE’s hardness value serves as a valuable marker for enhancing the preoperative diagnosis of malignant liver lesions,correlating significantly with MVI and antiviral treatment efficacy.
基金supported by the Outstanding Youth Project of Natural Science Foundation of Heilongjiang(YQ2023D006).
文摘Shear wave splitting(SWS)is regarded as the most effective geophysical method to delineate mantle flow fields by detecting seismic azimuthal anisotropy in the earth's upper mantle,especially in tectonically active regions such as subduction zones.The Aleutian-Alaska subduction zone has a convergence rate of approximately 50 mm/yr,with a trench length reaching nearly 2800 km.Such a long subduction zone has led to intensive continental deformation and numerous strong earthquakes in southern and central Alaska,while northern Alaska is relatively inactive.The sharp contrast makes Alaska a favorable locale to investigate the impact of subduction on mantle dynamics.Moreover,the uniqueness of this subduction zone,including the unusual subducting type,varying slab geometry,and atypical magmatic activity and composition,has intrigued the curiosity of many geoscientists.To identify different sources of seismic anisotropy beneath the Alaska region and probe the influence of a geometrically varying subducting slab on mantle dynamics,extensive SWS analyses have been conducted in the past decades.However,the insufficient station and azimuthal coverage,especially in early studies,not only led to some conflicting results but also strongly limited the in-depth investigation of layered anisotropy and the estimation of anisotropy depth.With the completion of the Transportable Array project in Alaska,recent studies have revealed more detailed mantle structures and characteristics based on the dense station coverage and newly collected massive seismic data.In this study,we review significant regional-and continental-scale SWS studies in the Alaska region and conclude the mantle flow fields therein,to understand how a geometrically varying subducting slab alters the regional mantle dynamics.The summarized mantle flow mechanisms are believed to be conducive to the understanding of seismic anisotropy patterns in other subduction zones with a complicated tectonic setting.
基金Supported by Sichuan Orthopaedic Hospital Research Project,No.2019MS02.
文摘BACKGROUND Real-time shear wave elastography(SWE)is a non-invasive imaging technique used to measure tissue stiffness by generating and tracking shear waves in real time.This advanced ultrasound-based method provides quantitative information regarding tissue elasticity,offering valuable insights into the mechanical properties of biological tissues.However,the application of real-time SWE in the musculoskeletal system and sports medicine has not been extensively studied.AIM To explore the practical value of real-time SWE for assessing Achilles tendon hardness in older adults.METHODS A total of 60 participants were enrolled in the present study,and differences in the elastic moduli of the bilateral Achilles tendons were compared among the following categories:(1)Age:55-60,60-65,and 65-70-years-old;(2)Sex:Male and female;(3)Laterality:Left and right sides;(4)Tendon state:Relaxed and tense state;and(5)Tendon segment:Proximal,middle,and distal.RESULTS There were no significant differences in the elastic moduli of the bilateral Achilles tendons when comparing by age or sex(P>0.05).There were,however,significant differences when comparing by tendon side,state,or segment(P<0.05).CONCLUSION Real-time SWE plays a significant role compared to other examination methods in the evaluation of Achilles tendon hardness in older adults.
文摘BACKGROUND Detection of early chronic changes in the kidney allograft is important for timely intervention and long-term survival.Conventional and novel ultrasound-based investigations are being increasingly used for this purpose with variable results.AIM To compare the diagnostic performance of resistive index(RI)and shear wave elastography(SWE)in the diagnosis of chronic fibrosing changes of kidney allograft with histopathological results.METHODS This is a cross-sectional and comparative study.A total of 154 kidney transplant recipients were included in this study,which was conducted at the Departments of Transplantation and Radiology,Sindh Institute of Urology and Transplantation,Karachi,Pakistan,from August 2022 to February 2023.All consecutive patients with increased serum creatinine levels and reduced glomerular filtration rate(GFR)after three months of transplantation were enrolled in this study.SWE and RI were performed and the findings of these were evaluated against the kidney allograft biopsy results to determine their diagnostic utility.RESULTS The mean age of all patients was 35.32±11.08 years.Among these,126(81.8%)were males and 28(18.2%)were females.The mean serum creatinine in all patients was 2.86±1.68 mg/dL and the mean estimated GFR was 35.38±17.27 mL/min/1.73 m2.Kidney allograft biopsy results showed chronic changes in 55(37.66%)biopsies.The sensitivity,specificity,positive predictive value(PPV),and negative predictive value(NPV)of SWE for the detection of chronic allograft damage were 93.10%,96.87%%,94.73%,and 95.87%,respectively,and the diagnostic accuracy was 95.45%.For RI,the sensitivity,specificity,PPV,and NPV were 76.92%,83.33%,70.17%,and 87.62%,respectively,and the diagnostic accuracy was 81.16%.CONCLUSION The results from this study show that SWE is more sensitive and specific as compared to RI in the evaluation of chronic allograft damage.It can be of great help during the routine follow-up of kidney transplant recipients for screening and early detection of chronic changes and selecting patients for allograft biopsy.
基金the U.S.Air Force Office of Scientific Research under grant AFOSR-FA9550-04-1-0220 and in part by The David and Lucille Packard Foundation.
文摘The ability to reliably detect coronary artery disease based on the acousticnoises produced by a stenosis can provide a simple, non-invasive technique for diagnosis.Current research exploits the shear wave fields in body tissue to detect andanalyze coronary stenoses. The methods and ideas outlined in earlier efforts [6] includinga mathematical model utilizing an internal strain variable approximation tothe quasi-linear viscoelastic constitutive equation proposed by Fung in [19] is extendedhere. As an initial investigation, a homogeneous two-dimensional viscoelastic geometryis considered. Being uniform in θ, this geometry behaves as a one dimensionalmodel, and the results generated from it are compared to the one dimensional resultsfrom [6]. To allow for different assumptions on the elastic response, several variationsof the model are considered. A statistical significance test is employed to determine ifthe more complex models are significant improvements. After calibrating the modelwith a comparison to previous findings, more complicated geometries are considered.Simulations involving a heterogeneous geometrywith a uniformring running throughthe original medium, a θ-dependent model which considers a rigid partial occlusionformed along the inner radius of the geometry, and a model which combines the ringand occlusion are presented.
文摘Two-dimensional scalar equation for the displacement of steady cross-plane shear (SH) waves in homogeneous and transversely isotropic media like unidirectional fibrous com-posites is given. Then, thrbugh a simple coordinate system transform, the scalar equation is standardized into a Helmholtz equation. Corresponding integral equations are derived for the scattering problems and boundary element method (BEM) is used to calculate the scattered fields of arbitrarily shaped obstacles with both soft and rigid boudary conditions numerically.A discussion is given on the numerical results which is mainly focused on the influence of the a-nisotropy of the media to the directivity of the scattered fields by circular cylindrical voids.
基金Russian Foundation for Basic Research,grant number 18-05-70002.
文摘Cyclic freezing-thawing can lead to fracture development in coal,affecting its mechanical and consumer properties.To study crack formations in coal,an ultrasonic sounding method using shear polarized waves was proposed.Samples of three coal types(anthracite,lignite and hard coal)were tested.The research results show that,in contrast to the shear wave velocity,the shear wave amplitude is extremely sensitive to the formation of new cracks at the early stages of cyclic freezing-thawing.Tests also show an inverse correlation between coal compressive strength and its tendency to form cracks under temperature impacts;shear wave attenuation increases more sharply in high-rank coals after the first freezing cycle.Spectral analysis of the received signals also confirmed significant crack formation in anthracite after the first freeze-thaw cycle.The initial anisotropy was determined,and its decrease with an increase in the number of freeze-thaw cycles was shown.The data obtained forms an experimental basis for the development of new approaches to preserve coal consumer properties during storage and transportation under severe natural and climatic conditions.
基金This work is jointly supported by the National Natural Science Foundation of China(No.41904057)the National Key Research and Development Program of China(No.2018YFC1503402).
文摘The Shimian area of Sichuan sits at the junction of the Bayan Har block.Sichuan-Yunnan rhombic block,and Yangtze block,where several faults intersect.This region features intense tectonic activity and frequent earthquakes.In this study,we used local seismic waveform data recorded using dense arrays deployed in the Shimian area to obtain the shear wave splitting parameters at 55 seismic stations and thereby determine the crustal anisotropic characteristics of the region.We then analyzed the crustal stress pattern and tectonic setting and explored their relationship in the study area.Although some stations returned a polarization direction of NNW-SSE.a dominant polarization direction of NW-SE was obtained for the fast shear wave at most seismic stations in the study area.The polarization directions of the fast shear wave were highly consistent throughout the study-area.This orientation was in accordance with the direction of the regional principal compressive stress and parallel to the trend of the Xianshuihe and Daliangshan faults.The distribution of crustal anisotropy in this area was affected by the regional tectonic stress field and the fault structures.The mean delay time between fast and slow shear waves was 3.83 ms/km.slightly greater than the values obtained in other regions of Sichuan.This indicates that the crustal media in our study area had a high anisotropic strength and also reveals the influence of tectonic complexity resulting from the intersection of multiple faults on the strength of seismic anisotropy.
文摘The discrete element method(DEM)is a capable tool used to simulate shear wave propagation in granular assemblies for many years.Researchers have studied assembly shapes such as rectangles(in 2D simulations)or cylinders and cubes(in 3D simulations).This paper aimed to qualify the effect of assembly shape on the shear wave propagation and maximum amplification in the vertical plane(horizontal and vertical directions)caused by this propagation.To this end,shear wave propagations in different assembly shapes such as rectangle,trapezium,and triangle with rigid boundary conditions were simulated.A sine wave pulse was applied with a point source by moving a particle as the transmitter particle.To evaluate the shear wave velocity of the assemblies,the transmitter and receiver particles were simulated.All the simulations were performed with 2D DEM which is a useful tool to determine the amount and location of the maximum amplification factor of the assembly in both horizontal and vertical directions.An advantage of this study was assessing the effect of parameters such as input wave frequency,assembly height,shape,and aspect ratios on the amplification of the input waves.
文摘BACKGROUND The treatment of hepatitis C with direct-acting antiviral agents(DAAs)produces a high rate of sustained virological response(SVR)with fewer adverse events than interferon(IFN)therapy with a similar effect in inhibiting carcinogenesis as IFN therapy.The age-male-albumin-bilirubin-platelets(aMAP)score is useful for stratifying the risk of hepatocellular carcinoma in chronic hepatitis patients,and the velocity of shear waves(Vs)measured by shear wave elastography has also been shown to be useful for diagnosing the level of fibrotic progression in hepatitis C and predicting carcinogenic risk.Combining these two may improve the prediction of carcinogenic risk.AIM To determine whether combining the aMAP score with Vs improves carcinogenic risk stratification in medium-to-high-risk hepatitis C patients.METHODS This retrospective,observational study involved hepatitis C patients treated with DAAs who achieved SVR.Vs was measured before treatment(baseline),at the end of treatment(EOT),and 12 wk(follow-up 12)and 24 wk(follow-up 24)after treatment.The patients were followed for at least six months after EOT to determine whether cancer developed.Multiple regression analysis was used to identify factors contributing to hepatic carcinogenesis.The diagnostic performances of clinical parameters for predicting the presence of hepatocellular carcinoma were evaluated using receiver-operating characteristic(ROC)curve analyses.RESULTS A total of 279 patients(mean age 65.9 years,118 males,161 females)were included in the analysis.Multiple regression analysis was performed with carcinogenesis as the target variable and alanine aminotransferase,platelets,α-fetoprotein,Vs,and the Fib-4 index as explanatory variables;only Vs was found to be significant(P=0.0296).The cut-off value for Vs for liver carcinogenesis calculated using the ROC curve was 1.53 m/s.Carcinoma developed in 2.0%(3/151)of those with Vs<1.53 m/s and in 10.5%(9/86)of those with Vs≥1.53 m/s.CONCLUSION In hepatitis C patients after SVR,combining the aMAP score and Vs to stratify the risk of carcinogenesis is more efficient than uniform surveillance of all patients.
基金Project supported by the National Natural Science Foundation of China(Grant No.11405271)the China Postdoctoral Science Foundation(Grant No.2017M612901)+4 种基金the Fund from Chongqing Science and Technology Commission(Grant No.cstc2017jcyjAX0047)Chongqing Postdoctoral Special Foundation(Grant No.Xm2017109)the Fundamental Research Funds for Central Universities,China(Grant No.YJ201796)the Pre-research Key Laboratory Fund for Equipment(Grant No.61422070306)the Fund from the Laboratory of Advanced Space Propulsion(Grant No.LabASP-2017-10)
文摘Characterizing the gap eigenmode of shear Alfv′en waves(SAWs) and its interaction with energetic ions is important to the success of magnetically confined fusion. Previous studies have reported an experimental observation of the spectral gap of SAW on the on Large Plasma Device(LAPD)(Zhang et al. 2008 Phys. Plasmas 15 012103), a linear large plasma device(Gekelman et al. 1991 Rev. Sci. Instrum. 62 2875) possessing easier diagnostic access and lower cost compared with traditional fusion devices, and analytical theory and numerical gap eigenmode using ideal conditions(Chang 2014 Ph.D Thesis at Australian National University). To guide experimental implementation, the present work models the gap eigenmode of SAWs using exact LAPD parameters. A full picture of the wave field for previous experiment reveals that the previously observed spectral gap is not global but an axially local result. To form a global spectral gap, the number of magnetic mirrors has to be increased and stronger static magnetic field makes it clearer. Such a spectral gap is obtained for the magnetic field of B0(z) = 1.2 + 0.6 cos[2π(z-33.68)/3.63] with 7.74-m magnetic beach. By introducing two types of local defects(corresponding to Eθ(z0) = 0 and E’θ(z0) = 0 respectively), odd-parity and even-parity discrete eigenmodes are formed clearly inside the gap. The strength of these gap eigenmodes decreases significantly with collision frequency, which is consistent with previous studies. Parameter scans show that these gap eigenmodes can be even formed successfully for the field strength of B0(z) = 0.2 + 0.1 cos[2π(z-33.68)/3.63] and with only four magnetic mirrors, which are achievable by the LAPD at its present status. This work can serve as a strong motivation and direct reference for the experimental implementation of the gap eigenmode of SAWs on the LAPD and other linear plasma devices.
基金This study was reviewed and approved by the Ethics Committee of the Affiliated Hospital of Guizhou Medical University.
文摘BACKGROUND Primary breast diffuse large B-cell lymphoma(PB-DLBCL)is a rare subtype of non-Hodgkin lymphoma that accounts for<3%of extranodal lymphomas and 1%of breast tumors.Its diagnosis and management are challenging because of its rarity,heterogeneity,and aggressive behavior.Conventional ultrasound(US)is the first-line imaging modality for breast lesions;however,it has limited specificity and accuracy for PB-DLBCL.Shear wave elastography(SWE)is a novel US technique that measures tissue stiffness and may reflect the histological characteristics and biological behavior of breast lesions.AIM To compare the conventional US and SWE features of PB-DLBCL and evaluate their diagnostic performance and prognostic value.METHODS We retrospectively reviewed the clinical data and US images of 32 patients with pathologically confirmed PB-DLBCL who underwent conventional US and SWE before treatment.We analyzed conventional US features(shape,margin,orientation,echo,posterior acoustic features,calcification,and vascularity)and SWE features(mean elasticity value,standard deviation,minimum elasticity value,maximum elasticity value,and lesion-to-fat ratio)of the PB-DLBCL lesions.Using receiver operating characteristic curve analysis,we determined the optimal cutoff values and diagnostic performance of conventional US and SWE features.We also performed a survival analysis to assess the prognostic value of conventional US and SWE features.RESULTS The results showed that the PB-DLBCL lesions were mostly irregular in shape(84.4%),microlobulated or spiculated in margins(75%),parallel in orientation(65.6%),hypoechoic in echo(87.5%),and had posterior acoustic enhancement(65.6%).Calcification was rare(6.3%)and vascularity was variable(31.3%avascular,37.5%hypovascular,and 31.3%hypervascular).The mean elasticity value of PB-DLBCL lesions was significantly higher than that of benign breast lesions(113.4±46.9 kPa vs 27.8±16.4 kPa,P<0.001).The optimal cutoff value of the mean elasticity for distinguishing PB-DLBCL from benign breast lesions was 54.5 kPa,with a sensitivity of 93.8%,specificity of 92.9%,positive predictive value of 93.8%,negative predictive value of 92.9%,and accuracy of 93.3%.The mean elasticity value was also significantly correlated with Ki-67 expression level(r=0.612,P<0.001),which is a marker of tumor proliferation and aggressiveness.Survival analysis showed that patients with higher mean elasticity values(>54.5 kPa)had worse overall survival(OS)and progression-free survival(PFS)than those with lower mean elasticity values(<54.5 kPa)(P=0.038 for OS and P=0.027 for PFS).CONCLUSION Conventional US and SWE provide useful information for diagnosing and forecasting PB-DLBCL.SWE excels in distinguishing PB-DLBCL from benign breast lesions,reflects tumor proliferation and aggressiveness,and improves disease management.
基金Supported by National Key Research and Development Program(No.20220101172JC).
文摘The vibrator plate is the link between the vibroseis vehicle and the earth,as well as the core com-ponent of the vibrator vehicle.In this paper,the coupling effect between the vibrator plate and the earth is an-alyzed from two aspects of reaction tooth arrangement and reaction tooth conical angle,and three groups of experimental models are optimized and designed.The model construction and numerical analysis of the shear wave vibroseis vibrator plate are carried out with ANSYS software.The motion law between the vibration plate and the earth at work was studied,the strain energy of the three experimental models in operation,the maximum displacement of particle at the same position and other reference indices were compared and ana-lyzed,with 28 conical reaction teeth were arranged on both sides.The coupling effect between the vibration plate and the earth was best when the tooth angle was 60°.Compared with the toothless vibration plate,the energy efficiency is improved by about 20%,and the coupling effect between the vibrator plate and the earth is effectively enhanced.It is found that the coupling effect is enhanced through increasing the number of reac-tion teeth of the vibration plate by increasing the coupling area between the vibration plate and the earth.