Recently, the phase compensation technique has allowed the ultrasound to propagate through the skull and focus into the brain. However, the temperature evolution during treatment is hard to control to achieve effectiv...Recently, the phase compensation technique has allowed the ultrasound to propagate through the skull and focus into the brain. However, the temperature evolution during treatment is hard to control to achieve effective treatment and avoid over-high temperature. Proposed in this paper is a method to modulate the temperature distribution in the focal region. It superimposes two signals which focus on two preset different targets with a certain distance. Then the temperature distribution is modulated by changing triggering time delay and amplitudes of the two signals. The simulation model is established based on an 82-element transducer and computed tomography （CT） data of a volunteer＇s head. A finite- difference time-domain （FDTD） method is used to calculate the temperature distributions. The results show that when the distances between the two targets respectively are 7.5-12.5 mm on the acoustic axis and 2.0-3.0 mm in the direction perpendicular to the acoustic axis, a focal region with a uniform temperature distribution （64-65 ℃） can be created. Moreover, the volume of the focal region formed by one irradiation can be adjusted （26.8-266.7 mm3） along with the uniform temperature distribution. This method may ensure the safety and efficacy of HIFU brain tumor therapy.展开更多
The three-phase bridge inverter is used as the converter topology in the power controller for a 9 kW doubly salient permanent magnet （DSPM） motor. Compared with common three-phase bridge inverters, the proposed inve...The three-phase bridge inverter is used as the converter topology in the power controller for a 9 kW doubly salient permanent magnet （DSPM） motor. Compared with common three-phase bridge inverters, the proposed inverter works under more complicated conditions with different principles for special winding back EMFs, position signals of hall sensors, and the given mode of switches. The ideal steady driving principles of the inverter for the motor are given. The working state with asymmetric winding back EMFs, inaccurate position signals of hall sensors, and the changing input voltage is analyzed. Finally, experimental results vertify that the given anal ysis is correct.展开更多
According to the characteristic of global positioning system（GPS） reflection signals,a GPS delay mapping receiver system scheme is put forward,which not only satisfies the unmanned aerial vehicle（UAV） guidance loc...According to the characteristic of global positioning system（GPS） reflection signals,a GPS delay mapping receiver system scheme is put forward,which not only satisfies the unmanned aerial vehicle（UAV） guidance localization but also realizes height measurement.A code delay algorithm is put forward,which processes the direct and land reflected signal and outputs the navigation data and specular point.The GPS terrain reflected echo signal mathematical equation is inferred.The reflecting signal area,when the GPS signal passes the land,is analyzed.The height survey model reflected land surface characteristic is established.A simulation system which carries guidance localization of the UAV and the height measuring control through the GPS direct signal and the land reflected signal is designed,taken the GPS satellite as the illumination source,the receiver is put on the UAV.Then the UAV guidance signal,the GPS reflection signal and receiver＇s parallel processing are realized.The parallel processing reduces UAV＇s payload and raises system＇s operating efficiency.The simulation results confirms the validity of the model and also provides the basis for the UAV＇s optimization design.展开更多
The nucleosome is the fundamental unit of eukaryotic genomes.Its positioning in the promoter region plays a central role in regulating gene transcription.Experimental evidence suggests that the genomic DNA sequence is...The nucleosome is the fundamental unit of eukaryotic genomes.Its positioning in the promoter region plays a central role in regulating gene transcription.Experimental evidence suggests that the genomic DNA sequence is one important determinant of nucleosome positioning.Several approaches have been developed to predict nucleosome positions based on DNA sequence features,but the results indicate that there is room for improvement.This paper presents a new computational approach to predict genome-wide nucleosome locations in promoter regions.Importantly,the proposed approach outperforms existing approaches in yeast.Further anal-ysis demonstrates that DNA signals for nucleosome posi-tioning vary with species and composition of histones.Analysis of individual genes reveals that the role of the underlying DNA sequence in nucleosome positioning var-ies with genes.展开更多
The small ubiquitin-related modifier （SUMO） modification plays an important role in the regulation of abscisic acid （ABA） signaling, but the function of the SUMO protease, in ABA signaling, remains largely unknown...The small ubiquitin-related modifier （SUMO） modification plays an important role in the regulation of abscisic acid （ABA） signaling, but the function of the SUMO protease, in ABA signaling, remains largely unknown. Here, we show that the SUMO protease, ASPI positively regulates ABA signaling. Mutations in ASPI resulted in an ABA-insensitive phenotype, during early seedling develop- ment. Wild-type ASP1 successfully rescued, whereas an ASPI mutant （C577S）, defective in SUMO protease activity, failed to rescue, the ABA-insensitive phenotype of asp1-1. Expression of ABI5 and MYB3o target genes was attenuated in asp^-I and our genetic analyses revealed that ASP1 may function upstream of ABI5 and MYB3o.展开更多
In this paper, the problem of parameter estimation of the combined radar signal adopting chaotic pulse position modulation （CPPM） and linear frequency modulation （LFM）, which can be widely used in electronic count...In this paper, the problem of parameter estimation of the combined radar signal adopting chaotic pulse position modulation （CPPM） and linear frequency modulation （LFM）, which can be widely used in electronic countermeasures, is addressed. An approach is proposed to estimate the initial frequency and chirp rate of the combined signal by exploiting the second-order cyclostationarity of the intra-pulse signal. In addition, under the condition of the equal pulse width, the pulse repetition interval （PRI） of the combined signal is predicted using the low-order Volterra adaptive filter. Simulations demonstrate that the proposed cyclic autocorrelation Hough transform （CHT） algorithm is theoretically tolerant to additive white Gaussian noise. When the value of signal noise to ratio （SNR） is less than 4 dB, it can still estimate the intra-pulse parameters well. When SNR = 3 dB, a good prediction of the PRI sequence can be achieved by the Volterra adaptive filter algorithm, even only 100 training samples.展开更多
The Chinese economy always receives attention from the international community.According to data released by National Bureau of Statistics on January 18,the Chinese economy maintained sound growth in 2017,better than ...The Chinese economy always receives attention from the international community.According to data released by National Bureau of Statistics on January 18,the Chinese economy maintained sound growth in 2017,better than expected.China’s economic development remains stable,ramping up confidence in global growth.There were some pessimistic views about China’s economy.Especially when China’s GDP growth went down in 2014,some international media and economists talked a lot about the bleak prospects of the Chinese economy.The latest data show that China’s economy grew 6.9 percent year on展开更多
基金Project supported by the National Natural Science Foundation of China(Grant No.81272495)the Natural Science Foundation of Tianjin,China(Grant No.16JC2DJC32200)
文摘Recently, the phase compensation technique has allowed the ultrasound to propagate through the skull and focus into the brain. However, the temperature evolution during treatment is hard to control to achieve effective treatment and avoid over-high temperature. Proposed in this paper is a method to modulate the temperature distribution in the focal region. It superimposes two signals which focus on two preset different targets with a certain distance. Then the temperature distribution is modulated by changing triggering time delay and amplitudes of the two signals. The simulation model is established based on an 82-element transducer and computed tomography （CT） data of a volunteer＇s head. A finite- difference time-domain （FDTD） method is used to calculate the temperature distributions. The results show that when the distances between the two targets respectively are 7.5-12.5 mm on the acoustic axis and 2.0-3.0 mm in the direction perpendicular to the acoustic axis, a focal region with a uniform temperature distribution （64-65 ℃） can be created. Moreover, the volume of the focal region formed by one irradiation can be adjusted （26.8-266.7 mm3） along with the uniform temperature distribution. This method may ensure the safety and efficacy of HIFU brain tumor therapy.
文摘The three-phase bridge inverter is used as the converter topology in the power controller for a 9 kW doubly salient permanent magnet （DSPM） motor. Compared with common three-phase bridge inverters, the proposed inverter works under more complicated conditions with different principles for special winding back EMFs, position signals of hall sensors, and the given mode of switches. The ideal steady driving principles of the inverter for the motor are given. The working state with asymmetric winding back EMFs, inaccurate position signals of hall sensors, and the changing input voltage is analyzed. Finally, experimental results vertify that the given anal ysis is correct.
基金supported by the National High Technology Researchand Development Program of China(863 Program)(2008AA12A216)
文摘According to the characteristic of global positioning system（GPS） reflection signals,a GPS delay mapping receiver system scheme is put forward,which not only satisfies the unmanned aerial vehicle（UAV） guidance localization but also realizes height measurement.A code delay algorithm is put forward,which processes the direct and land reflected signal and outputs the navigation data and specular point.The GPS terrain reflected echo signal mathematical equation is inferred.The reflecting signal area,when the GPS signal passes the land,is analyzed.The height survey model reflected land surface characteristic is established.A simulation system which carries guidance localization of the UAV and the height measuring control through the GPS direct signal and the land reflected signal is designed,taken the GPS satellite as the illumination source,the receiver is put on the UAV.Then the UAV guidance signal,the GPS reflection signal and receiver＇s parallel processing are realized.The parallel processing reduces UAV＇s payload and raises system＇s operating efficiency.The simulation results confirms the validity of the model and also provides the basis for the UAV＇s optimization design.
基金supported by the National Natural Science Foundation of China(Grant No.60474075)。
文摘The nucleosome is the fundamental unit of eukaryotic genomes.Its positioning in the promoter region plays a central role in regulating gene transcription.Experimental evidence suggests that the genomic DNA sequence is one important determinant of nucleosome positioning.Several approaches have been developed to predict nucleosome positions based on DNA sequence features,but the results indicate that there is room for improvement.This paper presents a new computational approach to predict genome-wide nucleosome locations in promoter regions.Importantly,the proposed approach outperforms existing approaches in yeast.Further anal-ysis demonstrates that DNA signals for nucleosome posi-tioning vary with species and composition of histones.Analysis of individual genes reveals that the role of the underlying DNA sequence in nucleosome positioning var-ies with genes.
基金supported by grants from the National Natural Science Foundation of China(31670186)the Chinese Academy of Sciences(XDA08010105)
文摘The small ubiquitin-related modifier （SUMO） modification plays an important role in the regulation of abscisic acid （ABA） signaling, but the function of the SUMO protease, in ABA signaling, remains largely unknown. Here, we show that the SUMO protease, ASPI positively regulates ABA signaling. Mutations in ASPI resulted in an ABA-insensitive phenotype, during early seedling develop- ment. Wild-type ASP1 successfully rescued, whereas an ASPI mutant （C577S）, defective in SUMO protease activity, failed to rescue, the ABA-insensitive phenotype of asp1-1. Expression of ABI5 and MYB3o target genes was attenuated in asp^-I and our genetic analyses revealed that ASP1 may function upstream of ABI5 and MYB3o.
基金supported by the National Natural Science Foundation of China under Grant 61172116
文摘In this paper, the problem of parameter estimation of the combined radar signal adopting chaotic pulse position modulation （CPPM） and linear frequency modulation （LFM）, which can be widely used in electronic countermeasures, is addressed. An approach is proposed to estimate the initial frequency and chirp rate of the combined signal by exploiting the second-order cyclostationarity of the intra-pulse signal. In addition, under the condition of the equal pulse width, the pulse repetition interval （PRI） of the combined signal is predicted using the low-order Volterra adaptive filter. Simulations demonstrate that the proposed cyclic autocorrelation Hough transform （CHT） algorithm is theoretically tolerant to additive white Gaussian noise. When the value of signal noise to ratio （SNR） is less than 4 dB, it can still estimate the intra-pulse parameters well. When SNR = 3 dB, a good prediction of the PRI sequence can be achieved by the Volterra adaptive filter algorithm, even only 100 training samples.
文摘The Chinese economy always receives attention from the international community.According to data released by National Bureau of Statistics on January 18,the Chinese economy maintained sound growth in 2017,better than expected.China’s economic development remains stable,ramping up confidence in global growth.There were some pessimistic views about China’s economy.Especially when China’s GDP growth went down in 2014,some international media and economists talked a lot about the bleak prospects of the Chinese economy.The latest data show that China’s economy grew 6.9 percent year on
