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Single Photon Scattering in a Pair of Waveguides Coupled by a Whispering-Gallery Resonator Interacting with a Semiconductor Quantum Dot 被引量:2
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作者 程木田 叶根龙 +1 位作者 纵卫卫 马小三 《Chinese Physics Letters》 SCIE CAS CSCD 2016年第2期47-50,共4页
The single photon scattering properties in a pair of waveguides coupled by a whispering-gallery resonator in- teracting with a semiconductor quantum dot are investigated theoretically. The two waveguides support four ... The single photon scattering properties in a pair of waveguides coupled by a whispering-gallery resonator in- teracting with a semiconductor quantum dot are investigated theoretically. The two waveguides support four possible ports for an incident single photon. The quantum dot is considered a V-type system. The incident direction-dependent single photon scattering properties are studied and equal-output probability from the four ports for a single photon incident is discussed. The influences of backscattering between the two modes of the whispering-gallery resonator for incident direction-dependent single photon scattering properties are also pre- sented. 展开更多
关键词 of is from in single photon Scattering in a Pair of Waveguides Coupled by a Whispering-Gallery resonator Interacting with a Semiconductor Quantum Dot mode with by
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Single-Photon Scattering by a Three-level System Interacting with a Whispering-Gallery Resonator Coupled to One-Dimensional Waveguide:
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作者 CHENG Mu-Tian SONG Yan-Yan LUO Ya-Qin ZHAO Guang-Xing 《Communications in Theoretical Physics》 SCIE CAS CSCD 2011年第3期501-505,共5页
We investigate theoretically the single-photon scattering by a A-type three-level system interacting with a whispering-gallery-type resonator which is coupled to a one-dimensional waveguide by full quantum-mechanical ... We investigate theoretically the single-photon scattering by a A-type three-level system interacting with a whispering-gallery-type resonator which is coupled to a one-dimensional waveguide by full quantum-mechanical approach. The single-photon transmission amplitude and reflection amplitude are obtained exactly via real-space approach. The single-photon transport properties controlling by classic optical field are discussed. The critical coupling condition in the coupled waveguide-whispering-gallery resonator-atom with three-level system is also analyzed. 展开更多
关键词 one-dimensional waveguide whispering gallery resonator SCATTERING single photon A-type threelevel
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Resonant cavity-enhanced quantum dot field-effect transistor as a single-photon detector
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作者 董宇 王广龙 +6 位作者 王红培 倪海桥 陈建辉 高凤岐 乔中涛 杨晓红 牛智川 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第10期162-167,共6页
A resonant cavity-enhanced (RCE) quantum dot (QD) field-effect transistor (RCEQDFET) is designed for single- photon detection in this paper. Adding distributed Bragg reflection (DBR) mirrors to the single-phot... A resonant cavity-enhanced (RCE) quantum dot (QD) field-effect transistor (RCEQDFET) is designed for single- photon detection in this paper. Adding distributed Bragg reflection (DBR) mirrors to the single-photon detector (SPD), we improve the light absorption efficiency of the SPD. The effects of the reflectivity of the mirrors, the thickness and light absorption coefficient of the absorbing layer on the detector's light absorption efficiency are investigated, and the resonant cavity is determined by using the air/semiconductor interface as the mirror on the top. Through analyzing the relationship between the refractive index of AlxGal_xAs and A1 component, we choose A1As/Alo.15Gao.85As as the material of the mirror on the bottom. The pairs of A1As/Alo.15Gao.85As film are further determined to be 21 by calculating the reflectivity of the mirror. The detector is fabricated from semiconductor heterostructures grown by molecular beam epitaxy. The reflection spectrum, photoluminescence (PL) spectrum, photocurrent response, and channel current of the detector are tested and the results show that the RCEQDFET-SPD designed in this paper has better performances in photonic response and wavelength selection. 展开更多
关键词 single-photon detector quantum dot field-effect transistor resonant cavity enhanced
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Low noise,continuous-wave single-frequency 1.5-μm laser generated by a singly resonant optical parametric oscillator 被引量:3
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作者 刘建丽 刘勤 +2 位作者 李宏 李鹏 张宽收 《Chinese Physics B》 SCIE EI CAS CSCD 2011年第11期312-316,共5页
We report a low noise continuous-wave (CW) single-frequency 1.5-μm laser source obtained by a singly resonant optical parametric oscillator (SRO) based on periodically poled lithium niobate (PPLN). The SRO was ... We report a low noise continuous-wave (CW) single-frequency 1.5-μm laser source obtained by a singly resonant optical parametric oscillator (SRO) based on periodically poled lithium niobate (PPLN). The SRO was pumped by a CW single-frequency Nd:YVO4 laser at 1.06μm. The 1.02 W of CW single-frequency signal laser at 1.5 μm was obtained at pump power of 6 W. At the output power of around 0.75 W, the power stability was better than ±l.5% and no mode-hopping was observed in 30 min and frequency stability was better than 8.5 MHz in 1 min. The signal wavelength could be tuned from 1.57 to 1.59 μm by varying the PPLN temperature. The 1.5-μm laser exhibits low noise characteristics, the intensity noise of the laser reaches the shot noise limit (SNL) at an analysis frequency of 4 MHz and the phase noise is less than 1 dB above the SNL at analysis frequencies above 10 MHz. 展开更多
关键词 singly resonant optical parametric oscillator 1.5-μm laser single-frequency operation low noise
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Resonantly driven exciton Rabi oscillation in single quantum dots emitting at 1300 nm 被引量:3
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作者 薛永洲 陈泽升 +4 位作者 倪海桥 牛智川 江德生 窦秀明 孙宝权 《Chinese Physics B》 SCIE EI CAS CSCD 2017年第8期185-188,共4页
We report on the resonance fluorescence (RF) from single InAs quantum dots (QDs) emitting at the telecom band of 1300 nm. The InAs/GaAs QDs are embedded in a planar optical microcavity and the RF is measured by an... We report on the resonance fluorescence (RF) from single InAs quantum dots (QDs) emitting at the telecom band of 1300 nm. The InAs/GaAs QDs are embedded in a planar optical microcavity and the RF is measured by an orthogonal excitation-detection geometry for deeply suppressing the residual laser scattering. An ultra-weak He-Ne laser is necessary to be used as a gate laser for obtaining RE Rabi oscillation with more than one period is observed through the picosecond (ps) pulsed laser excitation. The resonant control of exciton opens up new possibilities for realizing the on-demand single photon emission and quantum manipulation of solid-state qubits at telecom band. 展开更多
关键词 quantum dots resonance fluorescence single photons Rabi oscillation
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Microwave photonic filter with a continuously tunable central frequency using an SOI high-Q microdisk resonator 被引量:1
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作者 刘力 杨婷 董建绩 《Chinese Physics B》 SCIE EI CAS CSCD 2014年第9期165-169,共5页
Utilizing a high-Q microdisk resonator (MDR) on a single silicon-on-insulator (SOI) chip, a compact microwave photonic filter (MPF) with a continuously tunable central frequency is proposed and experimentally de... Utilizing a high-Q microdisk resonator (MDR) on a single silicon-on-insulator (SOI) chip, a compact microwave photonic filter (MPF) with a continuously tunable central frequency is proposed and experimentally demonstrated. Assisted by the optical single side-band (OSSB) modulation, the optical frequency response of the MDR is mapped to the microwave frequency response to form an MPF with a continuously tunable central frequency and a narrow 3-dB bandwidth. In the experiment, using an MDR with a compact size of 20×20 μm^2 and a high Q factor of 1.07×10^5, we obtain a compact MPF with a high rejection ratio of about 40 dB, a 3-dB bandwidth of about 2 GHz, and a frequency tuning range larger than 12 GHz. Our approach may allow the implementation of very compact, low-cost, low-consumption, and integrated notch MPF in a silicon chip. 展开更多
关键词 microwave photonic filter (MPF) microdisk resonator (MDR) silicon-on-insulator (SOI) chip optical single side-band (OSSB) modulation
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Diffusion-weighted magnetic resonance imaging with short T1 inversion recovery-echo planar imaging combined with dual-head coincidence single photon emission computed tomography for diagnosing solitary pulmonary nodule 被引量:1
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作者 WANG Wei XU Jin-zhi +1 位作者 ZHANG Tong SHEN Bao-zhong 《Chinese Medical Journal》 SCIE CAS CSCD 2010年第24期3717-3721,共5页
Positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) has not been widely used in China for expensive cost ($1200). Dual-head coincidence single photon emission computed tomography (DHC-SPECT) ... Positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) has not been widely used in China for expensive cost ($1200). Dual-head coincidence single photon emission computed tomography (DHC-SPECT) can depict many of the lesions depicted with a PET scanner in the lungs, which is used in place of PET-CT for discriminating malignant from benign pulmonary nodules in many studies. However, DHC-SPECT has inevitable false-negative results because the sensitivity for small lesions less than 2.0 cm is limited, and has high false-positive rate for active inflammatory nodules. Furthermore,DHC-SPECT also has a considerably higher cost ($300 in China) than other imaging examination. 展开更多
关键词 diffusion-weighted imaging magnetic resonance imaging decision tree analysis dual-head coincidence single photon emission computed tomography solitary pulmonary nodules lung cancer
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Resonant tunneling properties of photonic crystals consisting of single-negative materials 被引量:4
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作者 DENG XinHua LIU NianHua 《Chinese Science Bulletin》 SCIE EI CAS 2008年第4期529-533,共5页
We studied the resonant tunneling properties of one-dimensional photonic crystals consisting of single-negative permittivity and single-negative permeability media using transfer matrix methods.The results show that t... We studied the resonant tunneling properties of one-dimensional photonic crystals consisting of single-negative permittivity and single-negative permeability media using transfer matrix methods.The results show that there exists a pair of resonant tunneling modes in this structure.The separation of the pair of tunneling modes can be tuned by varying the ratio of thicknesses of the two single-negative layers or the thickness of the defect layer.The electric field intensity of the resonant tunneling modes increases rapidly with the increase of the ratio of thicknesses of the two single-negative layers.The peak value of the field intensity of the resonant tunneling modes is enhanced by one order of magnitude when the ratio of thicknesses of the two single-negative layers increases by 0.4.This property will be applied widely in the field of nonlinearity optics.With the increase of the ratio of thicknesses of the two single-negative layers,the electric field of the tunneling modes becomes more localized,and the full width at half maximum of the tunneling modes becomes narrower.Besides,the pair of tunneling modes is insensitive to incident angle and thickness fluctuation.These properties will be used for the design of tunable omnidirectional double-channel filter with high quality factor. 展开更多
关键词 单阴极材料 光子晶体 共振隧道效应 介电常数
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SPECT、SPECT-CT与MRI对新鲜骨质疏松性椎体压缩骨折的诊断价值 被引量:26
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作者 江晓兵 莫凌 +7 位作者 姚珍松 罗耀武 梁德 陆卫钦 张顺聪 丁金勇 杨志东 晋大祥 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2013年第10期891-897,共7页
目的:比较分析单光子发射计算机断层摄影术(SPECT)、单光子发射计算机断层摄影术联合同机CT扫描图像融合技术(SPECT-CT)与磁共振成像(MRI)对新鲜骨质疏松性椎体压缩骨折(OVCF)的诊断价值。方法:对2011年10月~2012年4月因OVCF... 目的:比较分析单光子发射计算机断层摄影术(SPECT)、单光子发射计算机断层摄影术联合同机CT扫描图像融合技术(SPECT-CT)与磁共振成像(MRI)对新鲜骨质疏松性椎体压缩骨折(OVCF)的诊断价值。方法:对2011年10月~2012年4月因OVCF就诊而又同时接受了胸腰椎MRI、SPECT及SPECT-CT检查的20例老年患者进行回顾性分析,其中女12例,男8例,年龄60~80岁,平均73.5岁,平均病程21d。根据MRI表现确定最终诊断,MRI上出现骨髓水肿像的椎体定义为新鲜骨折椎体,椎体形态有压缩改变但MRI信号无异常者定义为陈旧骨折。由2位核医学医师分别评估SPECT及SPECT-CT检查,记录出现核素浓集的椎体,并给出疾病诊断意见。采用Kappa检验对比MRI与SPECT-CT判断新鲜骨折及陈旧骨折的一致性以及定性诊断能力。参考MRI发现,采用卡方检验分析SPECT与SPECT-CT定位病椎能力的异同。结果:根据MRI或SPECT-CT,20例患者均确诊为新鲜OVCF,其中MRI发现32个椎体存在新鲜OVCF,SPECT-CT发现34个椎体存在新鲜OVCF;根据SPECT诊断新鲜OVCF 12例,疑似新鲜OVCF但难以与肿瘤、感染相鉴别8例,共发现34个椎体存在核素浓集。MRI发现新鲜OVCF 32个椎体、陈旧OVCF 10个椎体,SPECT-CT发现新鲜OVCF 34个椎体、陈旧OVCF 8个椎体,两者之间具有良好的一致性(Kappa=0.0577,P〈0.05)。在对病椎定位的准确性上,以MRI定位的病椎节段为参考,SPECT与MRI定位相同24个椎体,SPECT-CT与MRI定位相同30个椎体,SPECT-CT定位准确性优于SPECT(P〈0.05)。SPECT-CT检查还发现了MRI未能显示的骨骼病损,其中骶尾椎骨折1例,肋骨骨折2例,骶髂关节炎1例,胸锁关节良性病变1例。结论:SPECT-CT在OVCF的定位、定性诊断上与MRI的价值相似,其准确定位病椎的性能优于传统SPECT检查;SPECT-CT还可以发现一些MRI未能显示的合并骨骼病损。SPECT-CT是患者不能接受MRI时的可靠选择。 展开更多
关键词 椎体压缩骨折 单光子发射计算机断层摄影术 单光子发射计算机断层摄影术联合同机CT扫描图像融合技术 磁共振成像 骨质疏松
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SPECT-CT与MRI对确定骨质疏松性椎体压缩骨折疼痛责任椎体的价值比较 被引量:25
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作者 李永博 武汉 +3 位作者 韩硕 邓志洋 崔明超 赵明明 《中国脊柱脊髓杂志》 CAS CSCD 北大核心 2017年第11期997-1003,共7页
目的 :探讨单光子发射计算机断层摄影术联合同机CT扫描图像融合技术(single photon emission computed tomography-computed tomography,SPECT-CT)与磁共振成像(MRI)在确定骨质疏松性椎体压缩骨折(osteoporotic vertebral compression f... 目的 :探讨单光子发射计算机断层摄影术联合同机CT扫描图像融合技术(single photon emission computed tomography-computed tomography,SPECT-CT)与磁共振成像(MRI)在确定骨质疏松性椎体压缩骨折(osteoporotic vertebral compression fractures,OVCFs)疼痛责任椎体的一致性。方法 :选取2015年12月~2016年12月期间吉林大学中日联谊医院46例OVCFs患者,其中28例患者病程在3周之内,属于急性期骨折;18例病程在3周以上,属于非急性骨折。患者均行SPECT-CT和MRI检查,根据MRI及SPECT-CT共同确定疼痛责任椎体,行PKP术,采用疼痛视觉模拟评分法(visual analogue score,VAS)评估手术治疗效果,使用配对样本t检验分析治疗前后VAS评分,从而判定责任椎体的准确性,应用Kappa检验和Mc Nemar检验分析两种检查法的一致性和差异性,并计算SPECT-CT诊断的准确性指标。结果:46例患者中,MRI检查出OVCFs的责任节段79个,SPECT-CT检查出责任节段83个,最终77个椎体行PKP手术治疗。术前VAS评分8.33±2.12分,术后3天评分0.89±1.86分,术后1个月评分0.30±0.94分,较术前明显改善(P<0.05)。急性期28例患者共36个椎体行PKP手术治疗,MRI检查符合诊断标准的37个节段,SPECT-CT检查36个节段。非急性期18例患者共41个椎体行PKP手术治疗,MRI检查出42个节段,SPECT-CT检查出47个节段。分别将骨折不同时期的MRI和SPECT-CT的诊断结果进行Kappa检验,结果提示结果提示急性期两种检查方法高度一致(Kappa=0.943,P<0.05),非急性期一致性一般(Kappa=0.734,P<0.05)。对比不同时期骨折的SPECT-CT与MRI检查结果的符合性采用Mc Nemar检验,结果提示两种检验方法之间的差异不具有统计学意义(P>0.05)。此外,骨折的不同时期尤其是急性期,SPECT-CT与MRI的诊断性试验指标一致性较高。结论:SPECT-CT在骨质疏松性椎体压缩骨折的定位、定性上与MRI具有较高的一致性,尤其对于急性期骨折的患者,其具有较好的临床应用价值。 展开更多
关键词 骨质疏松椎体压缩骨折 单光子发射计算机断层摄影术联合同机CT扫描图像融合技术 磁共振成像 椎体后凸成形术
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rCBF-SPECT及MRA评价椎基底动脉供血不足性眩晕的价值 被引量:4
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作者 杨小丰 谭毓绘 +4 位作者 张林川 任永芳 张云 徐小煌 曹务成 《心血管康复医学杂志》 CAS 2002年第4期305-307,共3页
目的:探讨脑血流单光子断层显像(rCBF-SPECT)及磁共振血管造影(MRA)对椎基底动脉供血不足(VBI)性眩晕的评价价值。方法:对121例VBI患者(VBI组)和41例前庭周围性疾病(PVD)患者(对照组)均行rCBF-SPECT显像检查;VBI组66例,对照... 目的:探讨脑血流单光子断层显像(rCBF-SPECT)及磁共振血管造影(MRA)对椎基底动脉供血不足(VBI)性眩晕的评价价值。方法:对121例VBI患者(VBI组)和41例前庭周围性疾病(PVD)患者(对照组)均行rCBF-SPECT显像检查;VBI组66例,对照组29例行MRA检查。结果:VBI组rCBF-SPECT异常率93.38%.多数发生在左颞,MRA异常率65.15%(43/66),两者与对照组之间的差异均有显著性(P<0.01);VBI组rCBF-SPECT异常率明显高于MRA(P<0.01)。结论:rCBF-SPECT有助于脑功能及脑血流灌注状态的研究,MRA有助于脑供血减少的病因学研究,两者对VBI性眩晕的诊断和治疗均有指导意义。 展开更多
关键词 rCBF-SPECT MRA 椎基底动脉供血不足 眩晕 脑血流单光子断层显像 磁共振血管造影
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^(99)Tc^m-HMPAO-SPECT功能影像在胶质瘤评估中意义的比较研究 被引量:1
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作者 郭宗泽 李光宇 李亚明 《中国临床医学影像杂志》 CAS 北大核心 2007年第6期408-410,共3页
目的:为了评估99Tcm-HMPAO-SPECT影像在脑胶质瘤诊断中的意义。方法:72例经病理证实为胶质瘤的病人经作99Tcm-HMPAO单光子计算机断层扫描(SPECT)和核磁共振成像(MRI)检查。按WHO分类,其中包括33例低级别胶质瘤和39例高级别胶质瘤。使用... 目的:为了评估99Tcm-HMPAO-SPECT影像在脑胶质瘤诊断中的意义。方法:72例经病理证实为胶质瘤的病人经作99Tcm-HMPAO单光子计算机断层扫描(SPECT)和核磁共振成像(MRI)检查。按WHO分类,其中包括33例低级别胶质瘤和39例高级别胶质瘤。使用肿瘤感兴趣区与小脑比值(TCI)半定量损害区99Tcm-HMPAO的摄取。MRI显示的肿瘤增强、坏死和水肿被分为三个等级;损害的99Tcm-HMPAO的摄取指数与其组织学级别和MRI特点的关系被分别评估。结果:在高级别胶质瘤组32.6%的损害显示了高的99Tcm-HMPAO吸收(TCI>1.0),55.8%为低吸收(TCI<0.8),仅11.6%显示了与正常脑组织近似的中度吸收(TCI:0.8~1.0);在低级别胶质瘤组分别为10.3%,27.6%和62.1%,两组间TCI分布的差别是有意义的(P<0.01),同时肿瘤坏死和水肿对99Tcm-HMPAO吸收显示了有意义的影响。结论:与低级别胶质瘤相比,高级别胶质瘤的血流高低变化更为明显,肿瘤的坏死及水肿是导致局部血流降低的主要因素。 展开更多
关键词 脑肿瘤 神经胶质瘤 体层摄影术 发射型计算机 单光子 磁共振成像
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^(99)Tc^(m)-亚甲基二膦酸盐单光子发射计算机断层成像术/CT骨显影联合磁共振成像对退行性骨关节炎的临床价值 被引量:4
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作者 汪建强 陈春梦 廖杰 《实用医技杂志》 2021年第9期1065-1068,F0003,共5页
目的探讨多模态影像锝亚甲基二膦酸盐(^(99)Tc^(m)-MDP)单光子发射计算机断层成像术(SPECT)/CT骨显影联合磁共振成像(MRI)对退行性骨关节炎(OA)的临床价值。方法搜集53例OA及33例骨关节正常的患者行^(99)Tc^(m)-MDP SPECT/CT骨显影,对... 目的探讨多模态影像锝亚甲基二膦酸盐(^(99)Tc^(m)-MDP)单光子发射计算机断层成像术(SPECT)/CT骨显影联合磁共振成像(MRI)对退行性骨关节炎(OA)的临床价值。方法搜集53例OA及33例骨关节正常的患者行^(99)Tc^(m)-MDP SPECT/CT骨显影,对研究关节行SPECT/CT融合断层显影,利用勾画感兴趣区技术(ROI)测定各骨关节最大放射性计数,获得异常关节组和正常关节组的半定量靶/非靶(T/NT)放射性计数比值。在前后2周内完成MRI检查。结合临床资料、影像检查及随访结果进行统计对比分析,2组比值进行t检验,同时2种影像检查行χ^(2)检验。结果53例OA中46例放射性摄取为不均匀中高度浓聚,其关节放射性计数均值为(4.39±2.02),另7例轻度浓聚为稳定性骨质增生。33例正常组关节均值为(1.43±0.29),2组比较差异有统计学意义(t=-10.29,P<0.05)。MRI显示OA多为骨髓水肿、软骨水肿、毛糙、关节腔积液、周围软组织改变等异常信号。2种影像方法在OA诊断方面比较差异无统计学意义(χ^(2)=0.70,P>0.05),但侧重关节病变不同方面。结论多模态影像SPECT/CT骨显影联合MRI对OA的活动性病灶诊断、评估及随访复查具有重要临床价值及指导意义。 展开更多
关键词 磁共振成像 骨关节炎 多模态影像 骨显影 单光子发射计算机断层成像术/CT
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^1H-MRS和SPECT对脑肿瘤放疗后复发与放射性坏死的鉴别诊断价值 被引量:2
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作者 张泉 柏根基 《山东医药》 CAS 北大核心 2008年第25期22-24,共3页
目的探讨质子磁共振波谱(^1H-MRS)和^99mTc-甲氧基异丁基异腈(MIBI)单光子发射计算机断层显像(SPECT)对脑肿瘤患者放疗后复发(下称复发)与放射性坏死(下称坏死)的鉴别诊断作用。方法对35例脑肿瘤患者进行^1H-MRS和SPECT检查... 目的探讨质子磁共振波谱(^1H-MRS)和^99mTc-甲氧基异丁基异腈(MIBI)单光子发射计算机断层显像(SPECT)对脑肿瘤患者放疗后复发(下称复发)与放射性坏死(下称坏死)的鉴别诊断作用。方法对35例脑肿瘤患者进行^1H-MRS和SPECT检查。结果复发20例,^1H-MRS表现为胆碱(Cho)波上升,N-乙酰天门冬氨酸(NAA)波下降,乳酸和脂质波升高;^99mTc-MIBI摄取指数T/C比值1.9~6.7(3.7±1.5)。坏死15例,^1H-MRS表现为Cho、NAA、肌酸波降低;^99mTc-MIBI摄取指数T/C比值0.8~1.8(1.1±0.3)。两组比较均有统计学差异(P均〈0.01)。结论’H.MRS和SPECT检查对脑肿瘤复发及坏死有鉴别诊断价值。 展开更多
关键词 脑肿瘤 复发 坏死 放射性 质子磁共振波谱 单光子发射计算机断层显像
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Case Report:Lance-Adams syndrome:a report of two cases 被引量:6
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作者 ZHANG Yan-xing1,2, LIU Jian-ren1, JIANG biao3, LIU Hui-qin1, DING Mei-ping1, SONG Shui-jiang1, ZHANG Bao-rong1, ZHANG Hong4, XU Bin5, CHEN Huai-hong6, WANG Zhong-jin1, HUANG Jian-zheng1 (1Department of Neurology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China) (2Department of Neurology, Shaoxing People’s Hospital, Shaoxing 312000, China) (3Department of Radiology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China) (4Department of Nuclear Medicine, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China) (5Department of Neurology, the Second Affiliated Hospital, Zhejiang University of Traditional Chinese Medicine, Hangzhou 310005, China) (6Department of Geratology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China) 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 SCIE CAS CSCD 2007年第10期715-720,共6页
Chronic post-hypoxic myoclonus, also known as Lance-Adams syndrome (LAS), is a rare complication of successful cardiopulmanry resuscitation often accompanied by action myoclonus and cerebellar ataxia. It is seen in pa... Chronic post-hypoxic myoclonus, also known as Lance-Adams syndrome (LAS), is a rare complication of successful cardiopulmanry resuscitation often accompanied by action myoclonus and cerebellar ataxia. It is seen in patients who have un-dergone a cardiorespiratory arrest, regained consciousness afterwards, and then developed myoclonus days or weeks after the event. Worldwide, 122 cases have been reported in the literature so far, including 1 case of Chinese. Here we report 2 Chinese LAS patients with detailed neuroimagings. Cranial single photon emission computed tomography (SPECT) of patient 1, a 52-year-old woman, showed a mild hypoperfusion in her left temporal lobe, whereas patient 2, a 54-year-old woman, manifested a mild bilateral decrease of glucose metabolism in the frontal lobes and a mild to moderate decrease of the N-acetyl aspartate (NAA) peak in the bilateral hippocampi by cranial [18F]-fluorodeoxyglucose positron emission tomographic (PET) scan and cranial magnetic resonance spectroscopy (MRS), respectively. We also review the literature on the neuroimaging, pathogenesis, and treatment of LAS. 展开更多
关键词 Lance-Adams SYNDROME Chronic post-hypoxic MYOCLONUS Action MYOCLONUS CEREBELLAR ATAXIA single photon EMISSION computed TOMOGRAPHY Positron EMISSION TOMOGRAPHY Magnetic resonance spectroscopy
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Non-invasive detection of vulnerable coronary plaque 被引量:2
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作者 Faisal Sharif Derek G Lohan William Wijns 《World Journal of Cardiology》 CAS 2011年第7期219-229,共11页
Critical coronary stenosis have been shown to contribute to only a minority of acute coronary syndromes and sudden cardiac death.Autopsy studies have identified a subgroup of high-risk patients with disrupted vulnerab... Critical coronary stenosis have been shown to contribute to only a minority of acute coronary syndromes and sudden cardiac death.Autopsy studies have identified a subgroup of high-risk patients with disrupted vulnerable plaque and modest stenosis.Consequently,a clinical need exists to develop methods to identify these plaques prospectively before disruption and clinical expression of disease.Recent advances in invasive and non-invasive imaging techniques have shown the potential to identify these high-risk plaques.Non-invasive imaging with magnetic resonance imaging,computed tomography and positron emission tomography holds the potential to differentiate between low-and highrisk plaques.There have been significant technological advances in non-invasive imaging modalities,and the aim is to achieve a diagnostic sensitivity for these technologies similar to that of the invasive modalities.Molecular imaging with the use of novel targeted nanoparticles may help in detecting high-risk plaques that will ultimately cause acute myocardial infarction.Moreover,nanoparticle-based imaging may even provide non-invasive treatments for these plaques.However,at present none of these imaging modalities are able to detect vulnerable plaque nor have they been shown to definitively predict outcome.Further trials are needed to provide more information regarding the natural history of high-risk but non-flow-limiting plaque to establish patient specific targeted therapy and to refine plaque stabilizing strategies in the future. 展开更多
关键词 ATHEROSCLEROTIC PLAQUE Magnetic resonance imaging MULTIDETECTOR row COMPUTED TOMOGRAPHY single photon emission COMPUTED TOMOGRAPHY
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Imaging-based diagnosis of acute renal allograft rejection 被引量:2
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作者 Gerold Th?lking Katharina Schuette-Nuetgen +2 位作者 Dominik Kentrup Helga Pawelski Stefan Reuter 《World Journal of Transplantation》 2016年第1期174-182,共9页
Kidney transplantation is the best available treatment for patients with end stage renal disease. Despite the introduction of effective immunosuppressant drugs, episodes of acute allograft rejection still endanger gra... Kidney transplantation is the best available treatment for patients with end stage renal disease. Despite the introduction of effective immunosuppressant drugs, episodes of acute allograft rejection still endanger graft survival. Since efficient treatment of acute rejection is available, rapid diagnosis of this reversible graft injury is essential. For diagnosis of rejection, invasive core needle biopsy of the graft is the "gold-standard". However, biopsy carries the risk of significant graft injury and is not immediately feasible in patients taking anticoagulants. Therefore, a non-invasive tool assessing the whole organ for specific and fast detection of acute allograft rejection is desirable. We herein review current imaging-based state of the art approaches for non-invasive diagnostics of acute renal transplant rejection. We especially focus on new positron emission tomography-based as well as targeted ultrasoundbased methods. 展开更多
关键词 ACUTE ALLOGRAFT rejection IMAGING POSITRON EMISSION TOMOGRAPHY Ultrasound Magnetic resonance IMAGING single photon EMISSION computed TOMOGRAPHY Kidney transplantation Renal
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99Tcm-MDP全身骨显像联合局部SPECT/CT断层显像在骶骨功能不全性骨折中的诊断价值 被引量:13
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作者 丁浩源 蔡亮 +2 位作者 陈跃 张蜀茂 张莉 《中国医学影像学杂志》 CSCD 北大核心 2019年第8期612-617,共6页
目的比较CT、MRI和99Tc^m标记亚甲基二膦酸盐(MDP)全身骨显像联合局部SPECT/CT断层显像诊断骶骨功能不全性骨折(SIF)的临床价值。资料与方法回顾性分析55例X线平片无明显异常而临床高度怀疑SIF的患者,所有患者均进一步行CT、MRI和全身... 目的比较CT、MRI和99Tc^m标记亚甲基二膦酸盐(MDP)全身骨显像联合局部SPECT/CT断层显像诊断骶骨功能不全性骨折(SIF)的临床价值。资料与方法回顾性分析55例X线平片无明显异常而临床高度怀疑SIF的患者,所有患者均进一步行CT、MRI和全身骨显像及局部SPECT/CT断层显像。结合影像学表现、临床及随访确定诊断,分析其CT、MRI和全身骨显像及局部SPECT/CT断层显像表现,对比3种检查诊断SIF的差异。结果31例患者确诊为SIF。CT、MRI和全身骨显像联合局部SPECT/CT断层显像诊断SIF的敏感度分别为74.2%、87.5%和80.0%,特异度分别为80.6%、91.7%和85.5%,准确度分别为100%、83.3%和92.7%;全身骨显像联合局部SPECT/CT断层显像的敏感度和准确度与MRI、CT比较,差异有统计学意义(P<0.05);而MRI与CT比较,差异均无统计学意义(P>0.05)。结论与CT和MRI相比,全身骨显像联合局部SPECT/CT断层显像诊断SIF具有更好的准确性。 展开更多
关键词 骨折 应力性 骶骨 体层摄影术 螺旋计算机 磁共振成像 体层摄影术 发射型计算机 单光子 99M锝美罗酸盐
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Ultra-wide tuning single channel filter based on one-dimensional photonic crystal with an air cavity 被引量:1
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作者 Xiaodan Zhao Yibiao Yang +3 位作者 Zhihui Chen Yuncai Wang Hongming Fei Xiao Deng 《Journal of Semiconductors》 EI CAS CSCD 2017年第2期26-30,共5页
By inserting an air cavity into a one-dimensional photonic crystal of LiF/GaSb, a tunable filter covering the whole visible range is proposed. Following consideration of the dispersion of the materials, through modula... By inserting an air cavity into a one-dimensional photonic crystal of LiF/GaSb, a tunable filter covering the whole visible range is proposed. Following consideration of the dispersion of the materials, through modulating the thickness of the air cavity, we demonstrate that a single resonant peak can shift from 416.1 to 667.3 nm in the band gap at normal incidence by means of the transfer matrix method. The research also shows that the transmittance of the channel can be maximized when the number of periodic Li F/Ga Sb layers on one side of the air defect layer is equal to that of the other side. When adding a period to both sides respectively, the full width at half maximum of the defect mode is reduced by one order of magnitude. This structure will provide a promising approach to fabricate practical tunable filters in the visible region with ultra-wide tuning range. 展开更多
关键词 photonic crystal filters transfer matrix method single resonant peak ultra-wide tuning range mechanical modulation
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mpMRI联合^(99m)Tc-PSMA SPECT/CT检测前列腺癌新辅助雄激素剥夺治疗后显著残留病灶的价值研究 被引量:4
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作者 周冰妮 刘晓航 +2 位作者 顾丙新 周良平 顾雅佳 《中国癌症杂志》 CAS CSCD 北大核心 2022年第2期134-141,共8页
背景与目的:雄激素剥夺治疗(androgen deprivation therapy,ADT)是前列腺癌患者常用的治疗方法之一,然而对于ADT后病灶的变化,目前仍缺乏直接、精准的评估方法。以术后病理学检查结果作为金标准,初步探讨多参数磁共振成像(multiparametr... 背景与目的:雄激素剥夺治疗(androgen deprivation therapy,ADT)是前列腺癌患者常用的治疗方法之一,然而对于ADT后病灶的变化,目前仍缺乏直接、精准的评估方法。以术后病理学检查结果作为金标准,初步探讨多参数磁共振成像(multiparametric magnetic resonance imaging,mpMRI)联合^(99m)Tc标记前列腺特异性膜抗原(prostate specific membrane antigen,PSMA)小分子抑制剂(HYNIC-Glu-Urea-A,简称^(99m)Tc-PSMA)单光子发射计算机体层成像(single photon emission computed tomography,SPECT)/计算机体层成像(computed tomography,CT)评估前列腺癌新辅助ADT后的疗效,即检测显著残留病灶的价值。方法:回顾并分析2017年3月—2021年7月复旦大学附属肿瘤医院收治的154例接受新辅助ADT后行根治性前列腺切除术的前列腺癌患者的临床资料。所有患者均在术前行mpMRI及^(99m)Tc-PSMA SPECT/CT检查,根据术后病理学检查结果分为显著残留组及完全缓解/微残留两组。比较两组的临床病理学特征、mpMRI前列腺局部复发磁共振成像报告评分(Prostate Magnetic Resonance Imaging for Local Recurrence Reporting,PI-RR)分数及^(99m)Tc-PSMA SPECT/CT阳性率。采用受试者工作特征(receiver operating characteristic,ROC)曲线及曲线下面积(area under curve,AUC)分析mpMRI、^(99m)Tc-PSMA SPECT/CT单独使用及联合使用时的诊断效能差异。结果:术后病理学检查结果证实显著残留组128例、完全缓解/微残留组26例。患者平均年龄为(66.88±7.79)岁,中位年龄68岁,年龄47~85岁。两组患者年龄、初始PSA、Gleason评分差异无统计学意义(P>0.05);而新辅助ADT后PSA显著残留组明显高于完全缓解/微残留组,差异有统计学意义(P<0.05)。mpMRI诊断显著残留的AUC值为0.713,以PI-RR评分3为界值时灵敏度为78.13%,特异度为30.77%;以PI-RR评分4为界值时灵敏度为68.75%,特异度为69.23%。^(99m)Tc-PSMA SPECT/CT诊断显著残留的AUC值为0.729,与mpMRI相比差异无统计学意义(P>0.05),灵敏度为76.56%,特异度为69.23%。mpMRI联合^(99m)Tc-PSMA SPECT/CT使用时AUC为0.809,显著高于两者单独使用时(P<0.05)。结论:mpMRI与^(99m)Tc-PSMA SPECT/CT均可用于诊断前列腺癌新辅助ADT后显著残留灶,两者联合运用时可以显著提高诊断效能。 展开更多
关键词 前列腺癌 新辅助雄激素剥夺治疗 磁共振成像 前列腺特异性膜抗原 单光子发射计算机体层成像
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