The authors report clinical correlations of single photon emission computerized tomography (SPECT) findings in reversible posterior leukoencephalopathy (RPL). These are observations that have not received wide attenti...The authors report clinical correlations of single photon emission computerized tomography (SPECT) findings in reversible posterior leukoencephalopathy (RPL). These are observations that have not received wide attention in literature. A 31-year-old hypertensive gentleman, on discontinuing antihypertensive medications, presented with vomiting, headache, focal motor to bilateral tonic-clonic seizures, altered sensorium, right gaze palsy and right hemiparesis. Accelerated hypertension was noted and he improved well with antihypertensive and anticonvulsant therapy. While cranial magnetic resonance imaging (MRI) revealed extensive bilateral lesions, SPECT imaging revealed perfusion defects involving bilateral basal ganglia, left parieto-occipital, right cerebellar and right occipital regions, which corresponded with clinical deficits on examination. While MRI is the standard of care for the evaluation of RPL, this case suggests that SPECT abnormalities may be better localized to the pathogenic lesions. Furthermore, this may begin to explain the pathophysiology of injury in RPL.展开更多
目的总结Hawkeye SPECT/CT固有均匀性在日常质量控制中的校准方法,并分析其产生性能漂移的常见原因。方法选择我院2013年1月-6月Hawkeye仪器日常质控的部分数据,分析仪器的均匀性等基本情况;针对我院Hawkeye探头出现的中心视野＂亮点＂...目的总结Hawkeye SPECT/CT固有均匀性在日常质量控制中的校准方法,并分析其产生性能漂移的常见原因。方法选择我院2013年1月-6月Hawkeye仪器日常质控的部分数据,分析仪器的均匀性等基本情况;针对我院Hawkeye探头出现的中心视野＂亮点＂,而且中心视野均匀性（Center Field of View,CFOV）均匀性值偏离很大（23.17%）的现象,使用仪器提供的迭代校准程序（Iterative Calibration,ITER）进行校正。结果仪器固有均匀性通过校正后均可达到正常值（CFOV〈3.5%）。结论 Hawkeye仪器均匀性值的漂移可以通过有效的日常质量控制得到校准,通过校准可以使相机均匀性保持在较理想状态、仪器整体性能得以保证。展开更多
目的:评价单光子发射计算机断层显像(SPECT)检查过程中患者和照顾者的受照剂量及患者附近的周围剂量当量率,探讨SPECT检查过程中加强辐射防护的重要性。方法:采用In Light型光激发光(OSL)剂量计测量SPECT患者注射药物99Tcm后3 d内照顾...目的:评价单光子发射计算机断层显像(SPECT)检查过程中患者和照顾者的受照剂量及患者附近的周围剂量当量率,探讨SPECT检查过程中加强辐射防护的重要性。方法:采用In Light型光激发光(OSL)剂量计测量SPECT患者注射药物99Tcm后3 d内照顾者的个人剂量当量Hp(10),用γ剂量率仪测量SPECT患者注射药物99Tcm后距患者不同距离及不同方向的周围剂量当量率H·*(10)。结果:SPECT患者佩戴的个人剂量当量Hp(10)在0.45~1.12 m Sv之间,照顾者个人剂量当量Hp(10)在0.09~0.22 m Sv之间。注射放射性药物99Tcm后患者体表周围剂量当量率较高,一定距离处的剂量率显著下降,注射后5.5 h的周围剂量当量率降至注射后即刻测量结果的15%~25%。结论:在SPECT检查过程中,患者注射放射性药物99Tcm后其周围辐射水平较高,应加强防护及管理,提高专业工作人员的防护意识。展开更多
文摘The authors report clinical correlations of single photon emission computerized tomography (SPECT) findings in reversible posterior leukoencephalopathy (RPL). These are observations that have not received wide attention in literature. A 31-year-old hypertensive gentleman, on discontinuing antihypertensive medications, presented with vomiting, headache, focal motor to bilateral tonic-clonic seizures, altered sensorium, right gaze palsy and right hemiparesis. Accelerated hypertension was noted and he improved well with antihypertensive and anticonvulsant therapy. While cranial magnetic resonance imaging (MRI) revealed extensive bilateral lesions, SPECT imaging revealed perfusion defects involving bilateral basal ganglia, left parieto-occipital, right cerebellar and right occipital regions, which corresponded with clinical deficits on examination. While MRI is the standard of care for the evaluation of RPL, this case suggests that SPECT abnormalities may be better localized to the pathogenic lesions. Furthermore, this may begin to explain the pathophysiology of injury in RPL.
文摘目的总结Hawkeye SPECT/CT固有均匀性在日常质量控制中的校准方法,并分析其产生性能漂移的常见原因。方法选择我院2013年1月-6月Hawkeye仪器日常质控的部分数据,分析仪器的均匀性等基本情况;针对我院Hawkeye探头出现的中心视野＂亮点＂,而且中心视野均匀性（Center Field of View,CFOV）均匀性值偏离很大（23.17%）的现象,使用仪器提供的迭代校准程序（Iterative Calibration,ITER）进行校正。结果仪器固有均匀性通过校正后均可达到正常值（CFOV〈3.5%）。结论 Hawkeye仪器均匀性值的漂移可以通过有效的日常质量控制得到校准,通过校准可以使相机均匀性保持在较理想状态、仪器整体性能得以保证。
文摘目的:评价单光子发射计算机断层显像(SPECT)检查过程中患者和照顾者的受照剂量及患者附近的周围剂量当量率,探讨SPECT检查过程中加强辐射防护的重要性。方法:采用In Light型光激发光(OSL)剂量计测量SPECT患者注射药物99Tcm后3 d内照顾者的个人剂量当量Hp(10),用γ剂量率仪测量SPECT患者注射药物99Tcm后距患者不同距离及不同方向的周围剂量当量率H·*(10)。结果:SPECT患者佩戴的个人剂量当量Hp(10)在0.45~1.12 m Sv之间,照顾者个人剂量当量Hp(10)在0.09~0.22 m Sv之间。注射放射性药物99Tcm后患者体表周围剂量当量率较高,一定距离处的剂量率显著下降,注射后5.5 h的周围剂量当量率降至注射后即刻测量结果的15%~25%。结论:在SPECT检查过程中,患者注射放射性药物99Tcm后其周围辐射水平较高,应加强防护及管理,提高专业工作人员的防护意识。
