正常人新环境中睡眠第一晚效应研究

本研究旨在观察睡眠实验室的睡眠环境和实验操作对正常人新环境中第一晚睡眠的影响。描记１９例正常人在新环境中连续两晚的多导睡眠图。结果发现，第一晚的睡眠潜伏期延长，睡眠效率下降，深睡期和快动眼睡眠期减少。提示正常人的第一晚效应是存在的。

阻塞型睡眠呼吸暂停综合征96例临床分析

为观察不同程度的睡眠呼吸暂停综合征病人有关诊断指标与临床表现的相关关系。将多导脑电图仪改装成睡眠多导图监测仪。记录病人整夜睡眠时的脑电、眼动、肌电、心电、口鼻呼吸、胸腹呼吸、血压、脉搏及血氧饱和度（ＳａＯ２）等，并进行分析。阻塞型睡眠呼吸暂停综合征（ＯＳＡＳ）９６例，根据程度将其分为轻、中、重３个组。其呼吸暂停指数（ＡＨＩ）和ＳａＯ２的均值分别为１２．７７，７８．５％；３０．９９，７２．６２％；７３．９３，５６．８８％；总共低通气时间均值为１３．８８分，３４．９３分，１０３．５９分。说明随着ＡＨＩ的增加，总共低通气时间越长，ＯＳＡＳ的病情越重。肥胖与ＯＳＡＳ密切相关。

Effect of Huatan Jieyu granules in treatment of Parkinson’s disease patients with sleep disorder identified as symptom pattern of phlegma-heat-stirring wind

OBJECTIVE: To investigate the safety and efficacy of Huatan Jieyu granules in treatment of Parkinson’s disease(PD) patients with sleep disorder identified as symptom pattern of phlegma-heat-stirring wind in terms of the theory of Traditional Chinese Medicine.METHODS: In total, 107 Parkinson’s disease patients with sleep disorders identified as symptom pattern of phlegma-heat-stirring wind were selected and randomly divided into the experimental group(55 cases) and the control group(52 cases).Both groups were given basic treatment with prednisone. The experimental group of patients was treated with Huatan Jieyu granules and the control group of patents was treated with only the basic treatment. Treatment lasted for 4 weeks. Sleep polygraph were recorded before the study as well as 3 months and 6 months after treatment.RESULTS: After treated with Huatan Jieyu granules,the total sleep time, and the percentage of non rapid eye movement 2(NREM 2), non rapid eye movement 3(NREM 3) and rapid eye movement(REM)sleep period increased significantly, while the percentage of NREM1 sleep period decreased significantly compared with before treatment(P < 0.05).CONCLUSION: The treatment of PD patients with sleep disorder by Huatan Jieyu granules can improve their sleep structure and their sleep quality.