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Astrocytic calcium waves:unveiling their roles in sleep and arousal modulation
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作者 Erxi Wu Dan Qi +1 位作者 Damir Nizamutdinov Jason H.Huang 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第5期984-987,共4页
Neuron-astrocyte interactions are vital for the brain’s connectome.Understanding astrocyte activities is crucial for comprehending the complex neural network,particularly the population-level functions of neurons in ... Neuron-astrocyte interactions are vital for the brain’s connectome.Understanding astrocyte activities is crucial for comprehending the complex neural network,particularly the population-level functions of neurons in different cortical states and associated behaviors in mammals.Studies on animal sleep and wakefulness have revealed distinct cortical synchrony patterns between neurons.Astrocytes,outnumbering neurons by nearly fivefold,support and regulate neuronal and synaptic function.Recent research on astrocyte activation during cortical state transitions has emphasized the influence of norepinephrine as a neurotransmitter and calcium waves as key components of ion channel signaling.This summary focuses on a few recent studies investigating astrocyte-neuron interactions in mouse models during sleep,wakefulness,and arousal levels,exploring the involvement of noradrenaline signaling,ion channels,and glutamatergic signaling in different cortical states.These findings highlight the significant impact of astrocytes on large-scale neuronal networks,influencing brain activity and responsiveness.Targeting astrocytic signaling pathways shows promise for treating sleep disorders and arousal dysregulation.More research is needed to understand astrocytic calcium signaling in different brain regions and its implications for dysregulated brain states,requiring future human studies to comprehensively investigate neuron-astrocyte interactions and pave the way for therapeutic interventions in sleep-and arousal-related disorders. 展开更多
关键词 AROUSAL ASTROCYTE calcium waves locus coeruleus neuron-astrocyte interaction NOREPINEPHRINE sleep wakeFULNESS
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Nasal Cycle Dilemma: Nasal Cycle Is Associated to Brain Wake/REM States or Is Associated to Conscious State in Them?
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作者 Atanas Todorov Atanasov 《Open Journal of Biophysics》 2019年第1期1-9,共9页
Experimental and theoretical arguments have been described in favor of the hypothesis that the nasal cycle reversals of the nostril’s airflow occurs only in the consciousness states of the brain (during awake/wake st... Experimental and theoretical arguments have been described in favor of the hypothesis that the nasal cycle reversals of the nostril’s airflow occurs only in the consciousness states of the brain (during awake/wake state, REM state and during dreams in St.1, 2 of the non-REM sleep). This finding gives possibility to use nasal cycle as “marker for consciousness states”. An idea for clinical application of the hypothesis is proposed. 展开更多
关键词 NASAL cycle sleep cycle Consciousness EEG Waves
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An Energy-Efficient Duty-Cycled Wake-Up Radio Protocol for Avoiding Overhearing in Wireless Sensor Networks
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作者 Jean Mickael Lebreton Somasekhar Kandukuri +1 位作者 Nour Murad Richard Lorion 《Wireless Sensor Network》 2016年第8期176-190,共15页
Wake-up radio (WuR) system is often presented as the best candidate for replacing traditional duty cycled Medium Access Control (MAC) protocols in Wireless Sensor Networks (WSNs). The Double Radio (DoRa) protocol is a... Wake-up radio (WuR) system is often presented as the best candidate for replacing traditional duty cycled Medium Access Control (MAC) protocols in Wireless Sensor Networks (WSNs). The Double Radio (DoRa) protocol is a new MAC protocol for in-band WuR system with addressing capabilities. While the DoRa protocol improves the WSNs energy efficiency, it still suffers from an overhearing problem when the WuR system is very often requested. The WuR wastes a noticeable amount of energy when overhearing to wake-up demand intended to other nodes, but it is neither measured nor solved in other works. In this paper, an adaptive duty-cycled DoRa (DC-DoRa) is then proposed to solve the overhearing problem. The primary concept of the work is to enable the WuR functionality before the node is addressed and to disable the WuR after the node sent data. Extensive simulations under OMNeT++ using real input parameters are then performed to show the significant energy-savings through the two protocols and the nearly suppression of overhearing with DC-DoRa. In fact, the mean power consumption is three-order below using the DoRa protocol compared to traditional MAC protocols. While overhearing can represent up to 93% of the WuR energy consumption with the DoRa protocol, it is reduced to only 1% with the DC-DoRa protocol. 展开更多
关键词 Wireless Sensor Networks wake-Up Radio MAC Protocol Energy Efficiency Duty cycling
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Genetically engineered systems revealed the roles of basal ganglia in sleep-wake regulation 被引量:1
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作者 黄志力 《中国药理学与毒理学杂志》 CAS CSCD 北大核心 2017年第5期470-470,共1页
The basal ganglia(BG) act as a cohesive functional unit that regulates motor function,habit formation,and reward/addictive behaviors. However,it is still not well understood how the BG maintains wakefulness and suppre... The basal ganglia(BG) act as a cohesive functional unit that regulates motor function,habit formation,and reward/addictive behaviors. However,it is still not well understood how the BG maintains wakefulness and suppresses sleep to achieve al these fundamental functions until genetical y engineered systems developed these years. Significant research efforts have recently been directed at developing genetic-molecular tools to achieve reversible and cell-type specific in vivo silencing or activation of neurons in behaving animals. Optogenetic tools can be used both to specifically activate or inhibit neurons of interest and identify functional synaptic connectivity between specific neuronal populations,both in vivo and in brain slices. Another recently developed system by Roth and colleagues permits the selective and ″remote″ manipulation(activation and silencing) of neuronal activity via all 3 major GPCR signaling pathways(G_i,G_s and G_q). These so-called ″ designer receptors exclusively activated by designer drugs″(DREADD) involve mutant GPCRs that do not respond to their endogenous ligands but are responsive to otherwise inert biological compounds. Recently,we demonstrated the essential roles and the neural pathways of the neurons expressing adenosine A_(2A) receptors or dopamine D_1 receptors in the BG for sleep-wake regulation using the genetically engineered systems including optogenetics and DREADD. We proposed a plausible model in which the caudate-putamen and the nucleus accumbens integrates behavioral processes with sleep/wakefulness through adenosine and dopamine receptors. 展开更多
关键词 adeno-associated virus OPTOGENETICS DREADD basal ganglia sleep-wake regulation
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Dynamic detection of wake-sleep transition with reaction time-magnitude 被引量:3
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作者 Chuang Gao Bin Chen Wei Wei 《Neural Regeneration Research》 SCIE CAS CSCD 2009年第7期552-560,共9页
BACKGROUND: According to observable behaviors, sleep and wakefulness are two fundamentally different behavioral states. Although electroencephalogram (EEG) is traditionally used to define sleep stage, it is difficu... BACKGROUND: According to observable behaviors, sleep and wakefulness are two fundamentally different behavioral states. Although electroencephalogram (EEG) is traditionally used to define sleep stage, it is difficult to detect or to quantify microarousals or disruptions during sleep. In addition initial sleep cannot be defined. It is thought that the wake-sleep transition cannot be defined by EEG patterns. OBJECTIVE: To observe the behavioral response magnitude during wake-sleep transition by EEG monitoring and to define the wake-sleep transition. DESIGN, TIME AND SETTING: A behavioral and neural network study was performed at the Key Lab of Human Being Development and Mental Health of Central China Normal University, and Lab of Brain and Cognitive Science of South Central University for Nationalities, China in July 2007. PARTICIPANTS: A total of 30 healthy volunteers, of equal gender and aged (19.7 ± 1.1 ) years, were recruited from the Central China Normal University, China for this study. None of the subjects had undergone EEG recording prior to this study or received any medication for sleep disturbances. METHODS: A novel adaptive approach was applied to detect wake-sleep transition, which avoided stimulus-induced waking. To test the difference between wake state and wake-sleep transition, the amount of self-information and mutual-information were effective parameters to analyze wake-sleep transition. MAIN OUTCOME MEASURES: The following parameters were measured: morphological changes in reaction time-magnitude, as well as correlation between phase changes and sleep, and wake and wake-sleep transition. RESULTS: There were three typical phases in morphological changes of reaction time-magnitude. With regard to the behavioral definition and criterion for sleep, the phase morphological characteristics displayed good correlation with behavioral states, such as sleep, wakefulness, and sleep onset. Entropy as an indicator of brain cognitive processes was introduced to test for differences between the wakefulness and sleep onset phase. Results indicated a cognitive declined transitional period different between sleep and wake. After staggered cognitive changes during the wake-sleep transition, the brain underwent marked alterations and transitioned into sleep quickly with no bi-directional EEG changes. CONCLUSION: Wake-sleep transition exists as an independent stage. 展开更多
关键词 wake-sleep transition reaction time-magnitude ELECTROENCEPHALOGRAM sleep-wake states
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Photoacoustic treatment mitigates cognitive dysfunction in a model of sleep-wake rhythm disturbance 被引量:5
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作者 Fang Xing Xin Fang +5 位作者 Xiang-Dan Gong Xin Zhao Ying Du Zheng-Liang Ma Xiao-Ping Gu Tian-Jiao Xia 《Neural Regeneration Research》 SCIE CAS CSCD 2020年第6期1094-1101,共8页
Sleep-wake rhythm disturbances,which are characterized by abnormal sleep timing or duration,are associated with cognitive dysfunction.Photoacoustic treatments including light and sound stimulation have been found to b... Sleep-wake rhythm disturbances,which are characterized by abnormal sleep timing or duration,are associated with cognitive dysfunction.Photoacoustic treatments including light and sound stimulation have been found to be effective in modulating sleep patterns and improving cognitive behavior in abnormal sleep-wake pattern experiments.In this study,we examined whether light and sound interventions could reduce sleep-wake pattern disturbances and memory deficits in a sleep rhythm disturbance model.We established a model of sleep rhythm disturbance in C57 BL/6 J mice via a sleep deprivation method involving manual cage tapping,cage jostling,and nest disturbance.We used a Mini Mitter radio transmitter device to monitor motor activity in the mice and fear conditioning tests to assess cognitive function.Our results indicated that an intervention in which the mice were exposed to blue light(40-Hz flickering frequency)for 1 hour during their subjective daytime significantly improved the 24-hour-acrophase shift and reduced the degree of memory deficit induced by sleep deprivation.However,interventions in which the mice were exposed to a 40-Hz blue light at offset time or subjective night time points,as well as 2 Hz-blue light at 3 intervention time points(subjective day time,subjective night time,and offset time points),had no positive effects on circadian rhythm shift or memory deficits.Additionally,a 2000-Hz sound intervention during subjective day time attenuated the24-hour-acrophase shift and memory decline,while 440-Hz and 4000-Hz sounds had no effect on circadian rhythms.Overall,these results demonstrate that photoacoustic treatment effectively corrected abnormal sleep-wake patterns and cognitive dysfunction associated with sleep-deprivation-induced disturbances in sleep-wake rhythm.All animal experiments were approved by the Experimental Animal Ethics Committee of Drum Tower Hospital Affiliated to the Medical College of Nanjing University,China(approval No.20171102)on November20,2017. 展开更多
关键词 CIRCADIAN RHYTHM cognitive impairment fear conditioning light INTERVENTION photoacoustic treatment RHYTHM DISTURBANCE RHYTHM shift sleep DEPRIVATION sleep-wake RHYTHM sound INTERVENTION
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Lights at night:does photobiomodulation improve sleep? 被引量:1
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作者 Audrey Valverde Catherine Hamilton +3 位作者 Cécile Moro Malvina Billeres Pierre Magistretti John Mitrofanis 《Neural Regeneration Research》 SCIE CAS CSCD 2023年第3期474-477,共4页
Sleep is a critical part of our daily routine.It impacts every organ and system of our body,from the brain to the heart and from cellular metabolism to immune function.A consistent daily schedule of quality of sleep m... Sleep is a critical part of our daily routine.It impacts every organ and system of our body,from the brain to the heart and from cellular metabolism to immune function.A consistent daily schedule of quality of sleep makes a world of difference to our health and well-being.Despite its importance,so many individuals have trouble sleeping well.Poor quality sleep has such a detrimental impact on many aspects of our lives;it affects our thinking,learning,memory,and movements.Further,and most poignantly,poor quality sleep over time increases the risk of developing a serious medical condition,including neurodegenerative disease.In this review,we focus on a potentially new non-pharmacological treatment that improves the quality of sleep.This treatment,called photobiomodulation,involves the application of very specific wavelengths of light to body tissues.In animal models,these wavelengths,when applied at night,have been reported to stimulate the removal of fluid and toxic waste-products from the brain;that is,they improve the brain’s inbuilt house-keeping function.We suggest that transcranial nocturnal photobiomodulation,by improving brain function at night,will help improve the health and well-being of many individuals,by enhancing the quality of their sleep. 展开更多
关键词 aquaporin 4 glymphhatic infrared NON-PHARMACOLOGICAL red sleep cap TRANSCRANIAL wakeFULNESS
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Length of Periods in the Nasal Cycle during 24-Hours Registration
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作者 Atanas Todorov Atanasov 《Open Journal of Biophysics》 2014年第3期93-96,共4页
The periodic congestion and decongestion of the nasal venous sinuses and an alternation of airflow from one side of the nose to the other are known in literature as “nasal cycle”. It is established that nasal cycle ... The periodic congestion and decongestion of the nasal venous sinuses and an alternation of airflow from one side of the nose to the other are known in literature as “nasal cycle”. It is established that nasal cycle during 24-hours registration contains from 4 to 8 time full periods, length of which varies from 0.80 h to 5.75 h. The mean length of all full periods is 2.80 ± 0.17 h. The mean length of full periods of left nostril is 3.07 h and the mean length of periods of right nostril is 2.43 h. The result suggests that there is any asymmetry in length of periods of airflow trough left and right nostrils about 40 min. The longer periods of left nostril can be connected with higher metabolic and functional activity of brain and human organism during active work. 展开更多
关键词 NASAL cycle PERIODS of Nostril sleep cycle
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Wake-up effect in Hf_(0.4)Zr_(0.6)O_(2) ferroelectric thin-film capacitors under a cycling electric field
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作者 Yilin Li Hui Zhu +7 位作者 Rui Li Jie Liu Jinjuan Xiang Na Xie Zeng Huang Zhixuan Fang Xing Liu Lixing Zhou 《Chinese Physics B》 SCIE EI CAS CSCD 2022年第8期695-699,共5页
We examined the wake-up effect in a Ti N/Hf_(0.4)Zr_(0.6)O_(2)/TiN structure.The increased polarization was affected by the cumulative duration of a switched electric field and the single application time of the field... We examined the wake-up effect in a Ti N/Hf_(0.4)Zr_(0.6)O_(2)/TiN structure.The increased polarization was affected by the cumulative duration of a switched electric field and the single application time of the field during each switching cycle.The space-charge-limited current was stable,indicating that the trap density did not change during the wake-up.The effective charge density in the space-charge region was extracted from capacitance-voltage curves,which demonstrated an increase in free charges at the interface.Based on changing characteristics in these properties,the wake-up effect can be attributed to the redistribution of oxygen vacancies under the electric field. 展开更多
关键词 wake up HZO ferroelectric thin-film cycling electric field oxygen vacancy
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Significant change of sensitivity index d' in sensory processing of human brain during wake-sleep transition
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作者 Chuang Gao Fengjuan Zhang +2 位作者 Wei Wei Yang Zhang Shanyu Ke 《Neural Regeneration Research》 SCIE CAS CSCD 2011年第24期1894-1897,共4页
The sensor area in the brain remains active during the wake-sleep transition. However, the behavioral mechanisms of sensor sensitivity involved in the transition from a state of wakefulness to a sleep state remain poo... The sensor area in the brain remains active during the wake-sleep transition. However, the behavioral mechanisms of sensor sensitivity involved in the transition from a state of wakefulness to a sleep state remain poorly understood. To detect sensitivity index (d) changes during the wake-sleep transition, the present study recorded response times of wakefulness versus wake-sleep transition in 14 healthy undergraduate volunteers. During wake-sleep transition testing, morphological changes in the time courses of behavior response revealed 2 typical phases (stages A and B). In stage A, subject behavior responses exhibited temporal fluctuations, and all subjects displayed a high accuracy rate. In stage B, subjects did not exhibit behavioral responses. The sensitivity index d' during the wake-sleep transition (stage A) was significantly weaker than during wakefulness. Results demonstrated that at the behavioral level, sensation capacity for transfer information from the external world into the internal system significantly decreased during the transition to sleep. 展开更多
关键词 brain activation central nervous system neural regeneration sensitivity wakeFULNESS wake-sleep transition
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The influence of heterogeneity on the analysis of sleep-wake architecture in the single-prolonged stress rats
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作者 Ying WANG Hong-sheng BIAN +1 位作者 Hang ZHAO Ting-li LI 《中国应用生理学杂志》 CAS CSCD 2016年第6期504-508,共5页
Objective: To observe the influence of heterogeneity on sleep-wake architecture in single-prolonged stress(SPS) animal model. Methods: SPS rats were subdivided into low responders(LR) and high responders(HR) based on ... Objective: To observe the influence of heterogeneity on sleep-wake architecture in single-prolonged stress(SPS) animal model. Methods: SPS rats were subdivided into low responders(LR) and high responders(HR) based on their freezing responses to a novel environment. Sleeping time(ST), awakening numbers(AN), brief awakening numbers(b AN) and frequency distribution of sleep bouts were used as observing indicators, single factor variance analysis combined with Dunnett t test were used to compare the differences between control, exposure, LR and HR groups. Results: We found sleeping time was increased only in HR group. Moreover, awakening numbers and brief awakening number increased in exposure group and HR group during the light phase, but not in LR group. The number of sleep bouts for the ranges of 40-80 s increased obviously in HR group, but not in exposure and LR group. In addition, there were significant correlation between sleep-related parameters and freezing in HR group, but not in LR group. Conclusion: Heterogeneity existed in SPS model in view of different sleep-wake architectures of SPS rats. Rats in HR group exactly mimicked the freezing response and sleep disorders of PTSD. So HR rats were more appropriate to be used as PTSD-like models, especially when studying sleep disorder in PTSD. 展开更多
关键词 睡眠时间 异质性 大鼠 应激 结构 单因素方差分析 节段 动物模型
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俞募配穴联合脐针疗法治疗脑卒中后昼夜节律失调性睡眠-觉醒障碍的临床研究
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作者 曾友华 周文姬 +2 位作者 逄锦熙 袁健辉 包烨华 《中国现代医生》 2024年第7期30-33,79,共5页
目的探讨俞募配穴联合脐针疗法治疗脑卒中后昼夜节律失调性睡眠-觉醒障碍(circadian rhythm sleep-wake disorder,CRSWD)的临床疗效。方法选取2020年5月至2022年8月就诊于杭州市中医院的脑卒中后CRSWD患者87例为研究对象,根据随机数字... 目的探讨俞募配穴联合脐针疗法治疗脑卒中后昼夜节律失调性睡眠-觉醒障碍(circadian rhythm sleep-wake disorder,CRSWD)的临床疗效。方法选取2020年5月至2022年8月就诊于杭州市中医院的脑卒中后CRSWD患者87例为研究对象,根据随机数字表法将其分为治疗组(n=44)和对照组(n=43)。对照组患者予艾司唑仑片治疗,治疗组患者予俞募配穴联合脐针疗法治疗,观察两组患者治疗前、治疗5d、治疗2周的匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)和清晨型-夜晚型量表(morningness-eveningness questionnaire,MEQ)评分。结果两组患者的PSQI总分、PSQI-D、PSQI-G评分、MEQ评分以时点因素、时点与组别交互、组别为源的主体间效应比较,差异均有统计学意义(P<0.05);治疗2周后,治疗组患者的PSQI总分、PSQI-C、PSQI-D、PSQI-G评分均显著低于对照组,MEQ评分显著高于对照组(P<0.05)。结论俞募配穴联合脐针疗法治疗脑卒中后CRSWD可显著改善患者的睡眠质量,延长睡眠时间,改善日间功能状态,调整昼夜节律,有良好的临床疗效。 展开更多
关键词 脑卒中 睡眠障碍 昼夜节律失调性睡眠-觉醒障碍 针灸 俞募配穴 脐针疗法
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针刺运动疗法对改善痰瘀阻络型脑卒中后肩痛的临床效果
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作者 李燕 曹欣 巢小琳 《中国医药导报》 CAS 2024年第9期149-152,共4页
目的 分析针刺运动疗法对改善痰瘀阻络型脑卒中后肩痛的临床效果。方法 选取2020年3月至2022年9月江苏省常州市武进中医医院康复科收治的84例脑卒中后肩痛患者为对象,采用随机数字表法将其分为常规组和试验组,每组42例。常规组采用低周... 目的 分析针刺运动疗法对改善痰瘀阻络型脑卒中后肩痛的临床效果。方法 选取2020年3月至2022年9月江苏省常州市武进中医医院康复科收治的84例脑卒中后肩痛患者为对象,采用随机数字表法将其分为常规组和试验组,每组42例。常规组采用低周波治疗,试验组在常规组基础上给予针刺运动疗法治疗。于治疗前,治疗3、7、10 d时比较两组肩痛程度,于治疗前、治疗2周后比较两组改良Barthel指数(MBI),Fugl-Meyer评估表上肢部分(FMA-U)评分,匹兹堡睡眠质量量表(PSQI)评分。结果 常规组脱落1例,最终完成41例,试验组脱落3例,最张立完成39例。两组治疗3、7、10 d时肩痛程度评分均低于治疗前(P<0.05);试验组治疗3、7、10 d时肩痛程度评分低于常规组(P<0.05)。治疗后,两组MBI评分、FMA-U评分高于治疗前,PSQI评分低于治疗前,试验组MBI评分、FMA-U评分高于常规组,PSQI评分低于常规组(P<0.05)。治疗后,两组肩关节前屈、后伸、外展、内旋、外旋活动度较治疗前升高,且试验组高于常规组(P<0.05)。结论 针刺运动疗法可改善痰瘀阻络型脑卒中后肩痛程度和肩关节活动度,促进上肢运动功能的恢复,有利于提高睡眠质量。 展开更多
关键词 针刺运动疗法 低周波 痰瘀阻络型 脑卒中 肩痛 上肢运动功能 睡眠质量
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AUTOSAR标准的CAN网络休眠异常诊断机制研究 被引量:1
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作者 高永凡 李超超 +2 位作者 徐封杰 邱本胜 方菱 《计算机工程与应用》 CSCD 北大核心 2024年第7期248-257,共10页
汽车网络管理旨在保证节点间的通信状态同步及网络故障检测,是可靠的车载网络的重要组成部分。针对AUTOSAR网络管理中对于偶发的休眠异常难以定位与复现的问题,提出了一种基于唤醒链的网络休眠异常诊断机制,将管理报文在网络中出现的先... 汽车网络管理旨在保证节点间的通信状态同步及网络故障检测,是可靠的车载网络的重要组成部分。针对AUTOSAR网络管理中对于偶发的休眠异常难以定位与复现的问题,提出了一种基于唤醒链的网络休眠异常诊断机制,将管理报文在网络中出现的先后顺序与节点唤醒的先后顺序相对应,通过在网络管理报文中携带位置信息,实时记录网络节点在唤醒链中的位置,在偶发性故障出现时,将相关信息存入非易失性内存,之后通过重建唤醒链,恢复故障发生时网络中各节点的唤醒顺序及相关运行状态信息,帮助更准确高效地定位引发故障的节点,一定程度上解决了休眠异常难以复现和检测的问题。同时利用控制器局域网络CAN总线在实验平台CANoe上验证了该方法的有效性。 展开更多
关键词 AUTOSAR CAN总线 网络管理 唤醒链 休眠异常
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新生儿重症监护室早产儿睡眠促进的研究进展
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作者 慎斐 罗飞翔 徐红贞 《护理学杂志》 CSCD 北大核心 2024年第12期125-128,F0003,共5页
新生儿监护室中的早产儿由于全身器官尚未成熟,睡眠周期尚未建立,容易受到声音、光线等有害刺激的影响,这些刺激往往会扰乱并中断其睡眠。睡眠的中断对其神经及生长发育有着负面影响。本文对早产儿睡眠周期、评估工具和促进策略进行综述... 新生儿监护室中的早产儿由于全身器官尚未成熟,睡眠周期尚未建立,容易受到声音、光线等有害刺激的影响,这些刺激往往会扰乱并中断其睡眠。睡眠的中断对其神经及生长发育有着负面影响。本文对早产儿睡眠周期、评估工具和促进策略进行综述,旨在提高医护人员对早产儿睡眠保护的认知,为促进早产儿睡眠发育提供临床实践提供参考。 展开更多
关键词 早产儿 新生儿重症监护室 睡眠 睡眠周期 睡眠评估 睡眠促进 早产儿护理 综述文献
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基于可穿戴技术的运动员长期睡眠—觉醒行为的监测与分析
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作者 徐小凤 戴剑松 +2 位作者 陈钢锐 吕嘉乐 肖扬 《南京体育学院学报》 2024年第9期47-52,68,共7页
目的:睡眠是运动员恢复的重要组成部分。研究旨在通过长期监测分析击剑队运动员的睡眠—觉醒行为,为制订个性化训练和生活计划提供参考。方法:使用华为手环6在2023年4~9月期间收集了23名击剑运动员的睡眠数据。监测所获得的睡眠参数包... 目的:睡眠是运动员恢复的重要组成部分。研究旨在通过长期监测分析击剑队运动员的睡眠—觉醒行为,为制订个性化训练和生活计划提供参考。方法:使用华为手环6在2023年4~9月期间收集了23名击剑运动员的睡眠数据。监测所获得的睡眠参数包括入睡时间、出睡时间、深睡时长、浅睡时长、快速眼动时长、清醒时长和白天睡眠时长。在此期间,除比赛时期外,要求运动员每天24 h连续佩戴手环(洗澡及充电时间除外)。运动员每天通过专用APP将数据上传至HUAWEI Research云平台,研究人员随后从云平台下载并分析这些数据。结果:击剑运动员的平均夜间睡眠时长为7.97 h,不同性别运动员的睡眠参数无显著差异,水平高的运动员与运动等级低的运动员相比,除出睡时间(P=0.015)和睡眠中点(P=0.048)外,其他睡眠参数无显著差异;女运动员午睡频率显著高于男运动员(X^(2)=3.88,P=0.049),运动等级较高的运动员午睡频率显著高于运动等级低的运动员(X^(2)=11.97,P=0.001),白天小睡时长与晚上睡眠时长呈负相关(r=-0.270,P<0.001);观察星期一至星期日运动员睡眠—觉醒行为的变化,在没有早晨训练的星期一、星期三和星期五,运动员的出睡时间和睡眠中点显著后移,且训练日与休息日的睡眠参数存在显著差异。结论:击剑运动员的睡眠—觉醒行为受运动等级和训练计划安排的影响,并且在击剑运动员中存在睡眠节律紊乱的现象。 展开更多
关键词 击剑运动员 可穿戴技术 睡眠—觉醒行为 睡眠补偿
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ActiGraph(GT3X/±系列)加速度计睡眠筛查方法研究进展
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作者 聂明剑 程慧丽 +1 位作者 龙湘微 李红娟 《体育科学》 CSSCI 北大核心 2024年第5期72-83,共12页
基于加速度计的24 h活动行为研究中,计算不同活动行为时间之前,必须先将加速度计数据分为清醒时期(研究身体活动和久坐行为)和睡眠时期(研究睡眠时间和睡眠质量)。但目前关于加速度计数据对清醒-睡眠期的分离尚无公认的标准方法,也缺乏... 基于加速度计的24 h活动行为研究中,计算不同活动行为时间之前,必须先将加速度计数据分为清醒时期(研究身体活动和久坐行为)和睡眠时期(研究睡眠时间和睡眠质量)。但目前关于加速度计数据对清醒-睡眠期的分离尚无公认的标准方法,也缺乏对这些方法的系统梳理。研究从425篇相关文献中归纳出9种在自由生活条件下可用的清醒-睡眠期分离方法,通过解释这些方法的原理、优势与不足,为使用GT3X/±加速度计的研究人员提供选择睡眠筛查方法的建议:1)选择自动睡眠筛查算法时,腕部设备推荐使用GGIR内置的睡眠日记/HDCZA算法+van Hees 2015算法,腰部设备则可以选择Tracy ProChildren、Tudor-Locke、McVeigh或Bellettiere-McVeigh算法;2)选择Actilife进行睡眠筛查时,研究对象年龄<30岁时推荐使用Sadeh算法,≥30岁时推荐使用Cole-Kripke算法,且均需要睡眠日记的辅助。研究为24 h活动行为研究提供了数据处理方面的建议,也为未来开发新的清醒-睡眠期分离方法提供了方向,但仍需更多的研究来比较与验证这些睡眠筛查方法,以促进研究方法的标准化。 展开更多
关键词 加速度计 GT3X/± 24 h佩戴 睡眠筛查方法 清醒-睡眠期分离
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杏仁核对焦虑样睡眠障碍的调控
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作者 解俊樊 赵雪琪 +4 位作者 高进贤 任艳丽 杨兴文 邵玉峰 侯一平 《兰州大学学报(医学版)》 2024年第4期71-76,共6页
焦虑症常与睡眠障碍共存且相互作用,一方面睡眠障碍可引起焦虑,另一方面焦虑患者常出现失眠、睡眠片段化等焦虑样睡眠改变。基底外侧杏仁核和中央杏仁核与脑内多个睡眠-觉醒调控核团存在纤维联系,是调控焦虑样行为与睡眠的关键核团。本... 焦虑症常与睡眠障碍共存且相互作用,一方面睡眠障碍可引起焦虑,另一方面焦虑患者常出现失眠、睡眠片段化等焦虑样睡眠改变。基底外侧杏仁核和中央杏仁核与脑内多个睡眠-觉醒调控核团存在纤维联系,是调控焦虑样行为与睡眠的关键核团。本研究总结杏仁核解剖结构、纤维联系,以及杏仁核调节焦虑样行为与睡眠障碍的作用机制与神经环路,对进一步理解睡眠与焦虑相互作用的潜在机制具有重要意义,为临床治疗焦虑症和睡眠障碍提供理论基础。 展开更多
关键词 焦虑 睡眠-觉醒时相 杏仁核 睡眠障碍 快动眼睡眠 非快动眼睡眠
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支持接收唤醒机制的UART控制器设计
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作者 岳海群 翟翔 胡锦 《工业控制计算机》 2024年第8期34-36,共3页
UART是MCU芯片的常见串口通信外设。随着MCU在手持设备、物联网设备的应用越来越广泛,对低功耗需求也是越来越高。传统的UART为了降低功耗主要通过优化电路结构和算法,减少数据传输时的功耗,比如最常见的低功耗电荷泵技术,将电源电压调... UART是MCU芯片的常见串口通信外设。随着MCU在手持设备、物联网设备的应用越来越广泛,对低功耗需求也是越来越高。传统的UART为了降低功耗主要通过优化电路结构和算法,减少数据传输时的功耗,比如最常见的低功耗电荷泵技术,将电源电压调整至低的工作电压,从而降低功耗。介绍一种支持四种接收唤醒机制的低功耗UART电路,使用睡眠模式来降低电路功耗。实验验证,睡眠的UART接收器会在指定条件下硬件自动唤醒,然后正常地接收数据,降低功耗的同时能广泛运用在多机通信中。 展开更多
关键词 UART 低功耗 睡眠唤醒
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Reconsidering the role of depression and common psychiatric disorders as partners in the type 2 diabetes epidemic
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作者 Angelo Emilio Claro Clelia Palanza +10 位作者 Marianna Mazza Alessandro Rizzi Andrea Corsello Linda Tartaglione Giuseppe Marano Giovanna Elsa Ute Muti Schuenemann Marta Rigoni Alfredo Pontecorvi Luigi Janiri Paola Muti Dario Pitocco 《World Journal of Diabetes》 SCIE 2024年第6期1374-1380,共7页
Common psychiatric disorders(CPDs)and depression contribute significantly to the global epidemic of type 2 diabetes(T2D).We postulated a possible pathophysiological mechanism that through Bridge-Symptoms present in de... Common psychiatric disorders(CPDs)and depression contribute significantly to the global epidemic of type 2 diabetes(T2D).We postulated a possible pathophysiological mechanism that through Bridge-Symptoms present in depression and CPDs,promotes the establishment of emotional eating,activation of the reward system,onset of overweight and obesity and,ultimately the increased risk of developing T2D.The plausibility of the proposed pathophysiological mechanism is supported by the mechanism of action of drugs such as naltrexonebupropion currently approved for the treatment of both obesity/overweight with T2D and as separate active pharmaceutical ingredients in drug addiction,but also from initial evidence that is emerging regarding glucagon-like peptide 1 receptor agonists that appear to be effective in the treatment of drug addiction.We hope that our hypothesis may be useful in interpreting the higher prevalence of CPDs and depression in patients with T2D compared with the general population and may help refine the integrated psychiatric-diabetic therapy approach to improve the treatment and or remission of T2D. 展开更多
关键词 DEPRESSION Glucagon-like peptide-1 receptor agonists Diabetes mellitus type 2 Stress psychological sleep wake disorders Food addiction
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