<p> <span><span style="font-family:""><span style="font-family:Verdana;">Simulation (stochastic) methods are based on obtaining random samples </span><spa...<p> <span><span style="font-family:""><span style="font-family:Verdana;">Simulation (stochastic) methods are based on obtaining random samples </span><span style="color:#4F4F4F;font-family:Simsun;white-space:normal;background-color:#FFFFFF;"><span style="font-family:Verdana;">θ</span><sup><span style="font-family:Verdana;">5</span></sup></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"> </span><span><span style="font-family:Verdana;"> </span><span><span style="font-family:Verdana;">from the desired distribution </span><em><span style="font-family:Verdana;">p</span></em><span style="font-family:Verdana;">(</span><span style="color:#4F4F4F;font-family:Verdana;white-space:normal;background-color:#FFFFFF;">θ</span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;">)</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">and estimating the expectation of any </span></span><span><span style="font-family:Verdana;">function </span><em><span style="font-family:Verdana;">h</span></em><span style="font-family:Verdana;">(</span><span style="color:#4F4F4F;font-family:Verdana;white-space:normal;background-color:#FFFFFF;">θ</span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;">)</span><span style="font-family:Verdana;">. Simulation methods can be used for high-dimensional dis</span></span><span style="font-family:Verdana;">tributions, and there are general algorithms which work for a wide variety of models. Markov chain Monte Carlo (MCMC) methods have been important </span><span style="font-family:Verdana;">in making Bayesian inference practical for generic hierarchical models in</span><span style="font-family:Verdana;"> small area estimation. Small area estimation is a method for producing reliable estimates for small areas. Model based Bayesian small area estimation methods are becoming popular for their ability to combine information from several sources as well as taking account of spatial prediction of spatial data. In this study, detailed simulation algorithm is given and the performance of a non-trivial extension of hierarchical Bayesian model for binary data under spatial misalignment is assessed. Both areal level and unit level latent processes were considered in modeling. The process models generated from the predictors were used to construct the basis so as to alleviate the problem of collinearity </span><span style="font-family:Verdana;">between the true predictor variables and the spatial random process. The</span><span style="font-family:Verdana;"> performance of the proposed model was assessed using MCMC simulation studies. The performance was evaluated with respect to root mean square error </span><span style="font-family:Verdana;">(RMSE), Mean absolute error (MAE) and coverage probability of corres</span><span style="font-family:Verdana;">ponding 95% CI of the estimate. The estimates from the proposed model perform better than the direct estimate.</span></span></span></span> </p> <p> <span></span> </p>展开更多
Generalized Linear Mixed Model (GLMM) has been widely used in small area estimation for health indicators. Bayesian estimation is usually used to construct statistical intervals, however, its computational intensity i...Generalized Linear Mixed Model (GLMM) has been widely used in small area estimation for health indicators. Bayesian estimation is usually used to construct statistical intervals, however, its computational intensity is a big challenge for large complex surveys. Frequentist approaches, such as bootstrapping, and Monte Carlo (MC) simulation, are also applied but not evaluated in terms of the interval magnitude, width, and the computational time consumed. The 2013 Florida Behavioral Risk Factor Surveillance System data was used as a case study. County-level estimated prevalence of three health-related outcomes was obtained through a GLMM;and their 95% confidence intervals (CIs) were generated from bootstrapping and MC simulation. The intervals were compared to 95% credential intervals through a hierarchial Bayesian model. The results showed that 95% CIs for county-level estimates of each outcome by using MC simulation were similar to the 95% credible intervals generated by Bayesian estimation and were the most computationally efficient. It could be a viable option for constructing statistical intervals for small area estimation in public health practice.展开更多
Small area estimation (SAE) tackles the problem of providing reliable estimates for small areas, i.e., subsets of the population for which sample information is not sufficient to warrant the use of a direct estimator....Small area estimation (SAE) tackles the problem of providing reliable estimates for small areas, i.e., subsets of the population for which sample information is not sufficient to warrant the use of a direct estimator. Hierarchical Bayesian approach to SAE problems offers several advantages over traditional SAE models including the ability of appropriately accounting for the type of surveyed variable. In this paper, a number of model specifications for estimating small area counts are discussed and their relative merits are illustrated. We conducted a simulation study by reproducing in a simplified form the Italian Labour Force Survey and taking the Local Labor Markets as target areas. Simulated data were generated by assuming population characteristics of interest as well as survey sampling design as known. In one set of experiments, numbers of employment/unemployment from census data were utilized, in others population characteristics were varied. Results show persistent model failures for some standard Fay-Herriot specifications and for generalized linear Poisson models with (log-)normal sampling stage, whilst either unmatched or nonnormal sampling stage models get the best performance in terms of bias, accuracy and reliability. Though, the study also found that any model noticeably improves on its performance by letting sampling variances be stochastically determined rather than assumed as known as is the general practice. Moreover, we address the issue of model determination to point out limits and possible deceptions of commonly used criteria for model selection and checking in SAE context.展开更多
Demographic estimation becomes a problem of small area estimation when detaileddisaggregation leads to small cell counts.The usual difficulties of small area estimation are compounded when the available data sources c...Demographic estimation becomes a problem of small area estimation when detaileddisaggregation leads to small cell counts.The usual difficulties of small area estimation are compounded when the available data sources contain measurement errors.We present a Bayesianapproach to the problem of small area estimation with imperfect data sources.The overall modelcontains separate submodels for underlying demographic processes and for measurement processes.All unknown quantities in the model,including coverage ratios and demographic rates,are estimated jointly via Markov chain Monte Carlo methods.The approach is illustrated usingthe example of provincial fertility rates in Cambodia.展开更多
The linear mixed-effects model (LMM) is a very useful tool for analyzing cluster data. In practice, however, the exact values of the variables are often difficult to observe. In this paper, we consider the LMM with ...The linear mixed-effects model (LMM) is a very useful tool for analyzing cluster data. In practice, however, the exact values of the variables are often difficult to observe. In this paper, we consider the LMM with measurement errors in the covariates. The empirical BLUP estimator of the linear combination of the fixed and random effects and its approximate conditional MSE are derived. The application to the estimation of small area is provided. Simulation study shows good performance of the proposed estimators.展开更多
In this article,a new unit level model based on a pairwise penalised regression approach is proposed for problems in small area estimation(SAE).Instead of assuming common regression coefficients for all small domains ...In this article,a new unit level model based on a pairwise penalised regression approach is proposed for problems in small area estimation(SAE).Instead of assuming common regression coefficients for all small domains in the traditional model,the new estimator is based on a subgroup regression model which allows different regression coefficients in different groups.The alternating direction method of multipliers(ADMM)algorithm is used to find subgroups with different regression coefficients.We also consider pairwise spatial weights for spatial areal data.In the simulation study,we compare the performances of the new estimator with the traditional small area estimator.We also apply the new estimator to urban area estimation using data from the National Resources Inventory survey in Iowa.展开更多
Taking the accelerating aging and newly promoted urbanization as backdrops, this paper, on one side, analyzed the demands for parks, squares, fi tness facilities, chairs, etc. of elders in small towns from perspective...Taking the accelerating aging and newly promoted urbanization as backdrops, this paper, on one side, analyzed the demands for parks, squares, fi tness facilities, chairs, etc. of elders in small towns from perspectives of unique physical, psychological and social features of elders. On the other side, it also tackled the inadequacies of open spaces in small towns. Moreover, it proposed strategies such as creating social activity spaces, cultivating therapeutic green landscapes, constructing diversely secure fi tness spaces and building age integrated environments, etc. for designing age-friendly open spaces in small towns.展开更多
Based on the five-year long dynamic tracking and investigation of the peasant households of the Lishu village, the influences by small town construction on the economy and employment of the original peasant households...Based on the five-year long dynamic tracking and investigation of the peasant households of the Lishu village, the influences by small town construction on the economy and employment of the original peasant households are discussed. On the one hand, small town construction plays a positive role in adjustment of the industrial structure of the original peasant households and in the transfer of their employment towards non-agricultural industries. On the other hand the economic growth of the original peasant households is not so well sustainable, and is so fluctuating. Moreover, the unbalance of income distribution of the said households has been furthered, and small town construction has made the existing labor surplus of the original peasant households more serious, particularly the women labor surplus.展开更多
There are numerous types of living resources in coastal and offshore areas of China. In recent years,both the population type and quantity structure have significant changes,and the stock of small fishery population r...There are numerous types of living resources in coastal and offshore areas of China. In recent years,both the population type and quantity structure have significant changes,and the stock of small fishery population resources is increasing. This population is precious protein resource. It is urgent to study how to take prompt and effective fishing and take full advantage of processing,utilization and management. Traditional utilization methods are limited by many factors. The utilization efficiency is extremely low. The feed conversion rate of some mariculture fishes with fresh small trash fishes as feeds is even as low as 0. 2. Innovative production and management organization model with aquatic enterprises as leaders greatly increases the utilization efficiency of small fish resources with the aid of marine processing mother ship. In order to further accelerate developing and utilizing small fishery population resources in coastal and offshore areas,China should launch survey and utilization researches of small fishery population resources in coastal and offshore areas,formulate practical and feasible laws,regulations and policies,actively encourage and support autonomous innovative management mode of enterprises,and promote effective utilization and management of coastal and offshore fishery resources.展开更多
To preliminarily determine the appropriate dosage of carboplatin (CBP) at AUC of 5 mg-M1^-1·min^-1 in the combination chemotherapy for Chinese senile patients with non-small cell lung cancer (NSCLC). Thirty-f...To preliminarily determine the appropriate dosage of carboplatin (CBP) at AUC of 5 mg-M1^-1·min^-1 in the combination chemotherapy for Chinese senile patients with non-small cell lung cancer (NSCLC). Thirty-five Chinese senile patients with NSCLC in advanced stage (Ⅲ/Ⅳ) were given 96 cycles of combination chemotherapy. Chemotherapy schedules included Taxol+CBP, Gemzar+CBP and NVB+CBE The dose of CBP was at 5 mg.mL^-1·min^-1 of area under the concentration-time curve (AUC). Side effects and quality of life were observed before and after the chemotherapy. Myelosuppression was severe and commonly observed. Grade 3/4 of granulocytopenia was found in 47.9% (46/96) of the patients and grade 3/4 of thrombocytopenia was noted in 28.1% (27/96) of the subjects. However, other side effects were slight. The mean score of quality of life (QOL), according to the criteria of QOL for Chinese cancer patients had reduced 6.8. At 5 mg.mL^-1·min^-1 by AUC, the hematological toxicity of CBP was severe and it had some negative effects on the QOL. The administration of CBP at 5 mg.mL^-1·min^-1 by AUC may be too high for Chinese senile patients with non-small cell lung cancer.展开更多
文摘<p> <span><span style="font-family:""><span style="font-family:Verdana;">Simulation (stochastic) methods are based on obtaining random samples </span><span style="color:#4F4F4F;font-family:Simsun;white-space:normal;background-color:#FFFFFF;"><span style="font-family:Verdana;">θ</span><sup><span style="font-family:Verdana;">5</span></sup></span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;"> </span><span><span style="font-family:Verdana;"> </span><span><span style="font-family:Verdana;">from the desired distribution </span><em><span style="font-family:Verdana;">p</span></em><span style="font-family:Verdana;">(</span><span style="color:#4F4F4F;font-family:Verdana;white-space:normal;background-color:#FFFFFF;">θ</span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;">)</span><span style="font-family:Verdana;"> </span><span style="font-family:Verdana;">and estimating the expectation of any </span></span><span><span style="font-family:Verdana;">function </span><em><span style="font-family:Verdana;">h</span></em><span style="font-family:Verdana;">(</span><span style="color:#4F4F4F;font-family:Verdana;white-space:normal;background-color:#FFFFFF;">θ</span><span style="font-family:Verdana;"></span><span style="font-family:Verdana;">)</span><span style="font-family:Verdana;">. Simulation methods can be used for high-dimensional dis</span></span><span style="font-family:Verdana;">tributions, and there are general algorithms which work for a wide variety of models. Markov chain Monte Carlo (MCMC) methods have been important </span><span style="font-family:Verdana;">in making Bayesian inference practical for generic hierarchical models in</span><span style="font-family:Verdana;"> small area estimation. Small area estimation is a method for producing reliable estimates for small areas. Model based Bayesian small area estimation methods are becoming popular for their ability to combine information from several sources as well as taking account of spatial prediction of spatial data. In this study, detailed simulation algorithm is given and the performance of a non-trivial extension of hierarchical Bayesian model for binary data under spatial misalignment is assessed. Both areal level and unit level latent processes were considered in modeling. The process models generated from the predictors were used to construct the basis so as to alleviate the problem of collinearity </span><span style="font-family:Verdana;">between the true predictor variables and the spatial random process. The</span><span style="font-family:Verdana;"> performance of the proposed model was assessed using MCMC simulation studies. The performance was evaluated with respect to root mean square error </span><span style="font-family:Verdana;">(RMSE), Mean absolute error (MAE) and coverage probability of corres</span><span style="font-family:Verdana;">ponding 95% CI of the estimate. The estimates from the proposed model perform better than the direct estimate.</span></span></span></span> </p> <p> <span></span> </p>
文摘Generalized Linear Mixed Model (GLMM) has been widely used in small area estimation for health indicators. Bayesian estimation is usually used to construct statistical intervals, however, its computational intensity is a big challenge for large complex surveys. Frequentist approaches, such as bootstrapping, and Monte Carlo (MC) simulation, are also applied but not evaluated in terms of the interval magnitude, width, and the computational time consumed. The 2013 Florida Behavioral Risk Factor Surveillance System data was used as a case study. County-level estimated prevalence of three health-related outcomes was obtained through a GLMM;and their 95% confidence intervals (CIs) were generated from bootstrapping and MC simulation. The intervals were compared to 95% credential intervals through a hierarchial Bayesian model. The results showed that 95% CIs for county-level estimates of each outcome by using MC simulation were similar to the 95% credible intervals generated by Bayesian estimation and were the most computationally efficient. It could be a viable option for constructing statistical intervals for small area estimation in public health practice.
文摘Small area estimation (SAE) tackles the problem of providing reliable estimates for small areas, i.e., subsets of the population for which sample information is not sufficient to warrant the use of a direct estimator. Hierarchical Bayesian approach to SAE problems offers several advantages over traditional SAE models including the ability of appropriately accounting for the type of surveyed variable. In this paper, a number of model specifications for estimating small area counts are discussed and their relative merits are illustrated. We conducted a simulation study by reproducing in a simplified form the Italian Labour Force Survey and taking the Local Labor Markets as target areas. Simulated data were generated by assuming population characteristics of interest as well as survey sampling design as known. In one set of experiments, numbers of employment/unemployment from census data were utilized, in others population characteristics were varied. Results show persistent model failures for some standard Fay-Herriot specifications and for generalized linear Poisson models with (log-)normal sampling stage, whilst either unmatched or nonnormal sampling stage models get the best performance in terms of bias, accuracy and reliability. Though, the study also found that any model noticeably improves on its performance by letting sampling variances be stochastically determined rather than assumed as known as is the general practice. Moreover, we address the issue of model determination to point out limits and possible deceptions of commonly used criteria for model selection and checking in SAE context.
文摘Demographic estimation becomes a problem of small area estimation when detaileddisaggregation leads to small cell counts.The usual difficulties of small area estimation are compounded when the available data sources contain measurement errors.We present a Bayesianapproach to the problem of small area estimation with imperfect data sources.The overall modelcontains separate submodels for underlying demographic processes and for measurement processes.All unknown quantities in the model,including coverage ratios and demographic rates,are estimated jointly via Markov chain Monte Carlo methods.The approach is illustrated usingthe example of provincial fertility rates in Cambodia.
基金supported by National Natural Science Foundation of China(Grant No.11301514)partially supported by National Natural Science Foundation of China(Grant Nos.11271355 and 70625004)National Bureau of Statistics of China(Grant No.2012LZ012)
文摘The linear mixed-effects model (LMM) is a very useful tool for analyzing cluster data. In practice, however, the exact values of the variables are often difficult to observe. In this paper, we consider the LMM with measurement errors in the covariates. The empirical BLUP estimator of the linear combination of the fixed and random effects and its approximate conditional MSE are derived. The application to the estimation of small area is provided. Simulation study shows good performance of the proposed estimators.
基金This research was supported in part by the Natural ResourcesConservation Service of the U.S. Department of Agriculture.
文摘In this article,a new unit level model based on a pairwise penalised regression approach is proposed for problems in small area estimation(SAE).Instead of assuming common regression coefficients for all small domains in the traditional model,the new estimator is based on a subgroup regression model which allows different regression coefficients in different groups.The alternating direction method of multipliers(ADMM)algorithm is used to find subgroups with different regression coefficients.We also consider pairwise spatial weights for spatial areal data.In the simulation study,we compare the performances of the new estimator with the traditional small area estimator.We also apply the new estimator to urban area estimation using data from the National Resources Inventory survey in Iowa.
基金Sponsored by Humanities and Social Science Project of Jiangxi Colleges and Universities"Research on Aging-friendly Community Planning and Construction of Small Town in Jiangxi"(JC1434)"Twelfth Five-year Plan"of Jiangxi Provincial Social Sciences Planning Program(2014)"Construction of Comprehensive Elderly Service System in Residential Communities based on Settling the Elders in Original Site and Countermeasures"(14SH05)+1 种基金Jiangxi Normal University Scientif ic Research Program"Construction and Planning of the Urban Age-friendly Residential System in Underdeveloped Regions"(2013)Jiangxi Normal University Doctorial Fund"Research on Jiangxi Urban Elderly Friendly Community Comprehensive Social Planning Research(2014)"
文摘Taking the accelerating aging and newly promoted urbanization as backdrops, this paper, on one side, analyzed the demands for parks, squares, fi tness facilities, chairs, etc. of elders in small towns from perspectives of unique physical, psychological and social features of elders. On the other side, it also tackled the inadequacies of open spaces in small towns. Moreover, it proposed strategies such as creating social activity spaces, cultivating therapeutic green landscapes, constructing diversely secure fi tness spaces and building age integrated environments, etc. for designing age-friendly open spaces in small towns.
基金Supported by the Knowledge Innovation Program of Chinese Academy of Sciences(KZCZ2-316)and Ecology and Environment Compensation Foundation from the Office of the TGP Construction commission of the State council of China(SX2001-021)
文摘Based on the five-year long dynamic tracking and investigation of the peasant households of the Lishu village, the influences by small town construction on the economy and employment of the original peasant households are discussed. On the one hand, small town construction plays a positive role in adjustment of the industrial structure of the original peasant households and in the transfer of their employment towards non-agricultural industries. On the other hand the economic growth of the original peasant households is not so well sustainable, and is so fluctuating. Moreover, the unbalance of income distribution of the said households has been furthered, and small town construction has made the existing labor surplus of the original peasant households more serious, particularly the women labor surplus.
文摘There are numerous types of living resources in coastal and offshore areas of China. In recent years,both the population type and quantity structure have significant changes,and the stock of small fishery population resources is increasing. This population is precious protein resource. It is urgent to study how to take prompt and effective fishing and take full advantage of processing,utilization and management. Traditional utilization methods are limited by many factors. The utilization efficiency is extremely low. The feed conversion rate of some mariculture fishes with fresh small trash fishes as feeds is even as low as 0. 2. Innovative production and management organization model with aquatic enterprises as leaders greatly increases the utilization efficiency of small fish resources with the aid of marine processing mother ship. In order to further accelerate developing and utilizing small fishery population resources in coastal and offshore areas,China should launch survey and utilization researches of small fishery population resources in coastal and offshore areas,formulate practical and feasible laws,regulations and policies,actively encourage and support autonomous innovative management mode of enterprises,and promote effective utilization and management of coastal and offshore fishery resources.
基金a grant from a key research program of the Education Bureau of Hubei Province (D2006-02-002).
文摘To preliminarily determine the appropriate dosage of carboplatin (CBP) at AUC of 5 mg-M1^-1·min^-1 in the combination chemotherapy for Chinese senile patients with non-small cell lung cancer (NSCLC). Thirty-five Chinese senile patients with NSCLC in advanced stage (Ⅲ/Ⅳ) were given 96 cycles of combination chemotherapy. Chemotherapy schedules included Taxol+CBP, Gemzar+CBP and NVB+CBE The dose of CBP was at 5 mg.mL^-1·min^-1 of area under the concentration-time curve (AUC). Side effects and quality of life were observed before and after the chemotherapy. Myelosuppression was severe and commonly observed. Grade 3/4 of granulocytopenia was found in 47.9% (46/96) of the patients and grade 3/4 of thrombocytopenia was noted in 28.1% (27/96) of the subjects. However, other side effects were slight. The mean score of quality of life (QOL), according to the criteria of QOL for Chinese cancer patients had reduced 6.8. At 5 mg.mL^-1·min^-1 by AUC, the hematological toxicity of CBP was severe and it had some negative effects on the QOL. The administration of CBP at 5 mg.mL^-1·min^-1 by AUC may be too high for Chinese senile patients with non-small cell lung cancer.