[Objective]This paper aims to study the heredity and parental correlation of the oil content of the beginning of the generation at highoil content soybean.[Methods]Seven high yield or high-oil content soybean are sele...[Objective]This paper aims to study the heredity and parental correlation of the oil content of the beginning of the generation at highoil content soybean.[Methods]Seven high yield or high-oil content soybean are selected and eight crosses are made according to the NCII design.[Results]The variation of oil content in F5 relates with the difference between parents.The more the differences between both parents have,the more variations of the oil content of F5 become.When the oil content of both parents are high,and the maturating time of them are very different,the probability of high-oil plant in F5 derived from these cross are high.The oil content of F5 generation has negative correlation with the different between both parents and has positive correlation with the oil content of male parent and significant positive correlation with the oil content of female parent and mid-parent.[Conclusions]This study result provide reference for the seedling of High-oil Content Soybean.展开更多
The heredity of aluminum melt under the action of pulse electric field was investigated by means of the remelt experiment. A new hereditary criterion under this condition was proposed; in the meantime, the differentia...The heredity of aluminum melt under the action of pulse electric field was investigated by means of the remelt experiment. A new hereditary criterion under this condition was proposed; in the meantime, the differential transferability of genetic carrier in activated melt among filial generations was validated with the aid of DSC.展开更多
Using S-rough sets, this paper gives the concepts off-heredity knowledge and its heredity coefficient, and f-variation coefficient of knowledge; presents the theorem of f-attribute dependence of variation coefficient ...Using S-rough sets, this paper gives the concepts off-heredity knowledge and its heredity coefficient, and f-variation coefficient of knowledge; presents the theorem of f-attribute dependence of variation coefficient and the relation theorem of heredity-variation. The attribute dependence of f-variation coefficient and the relation of heredity-variation are important characteristics of S-rough sets. From such discussion, this paper puts forward the heredity mining off-knowledge and the algorithm of heredity mining, also gives its relative application.展开更多
Several risk factors,which include heredity,ultra-violet (UV) light and chronic inflammation,contribute to pterygium development.However,there is no report integrating these factors in the pathogenesis of pterygium.Th...Several risk factors,which include heredity,ultra-violet (UV) light and chronic inflammation,contribute to pterygium development.However,there is no report integrating these factors in the pathogenesis of pterygium.The aim of this review is to describe the connection between heredity,UV,and inflammation in pterygium development.Existing reports indicate that sunlight exposure is the main factor in pterygium occurrence by inducing growth factor production or chronic inflammation or DNA damage.Heredity may be a factor.Our studies on factors in pterygium occurrence and recurrence identify that heredity is crucial for pterygium to develop,and that sunlight is only a trigger,and that chronic inflammation promotes pterygium enlargement.We propose that genetic factors may interfere with the control of fibrovascular proliferation while UV light or(sunlight)most likely only triggers pterygium development by inducing growth factors which promote vibrant fibrovascular proliferation in predisposed individuals.It also just triggers inflammation and collagenolysis,which may be promoters of the enlargement of the fibrovascular mass.Pterygium probably occurs in the presence of exuberant collagen production and profuse neovascularisation.展开更多
Salt stress is one of the major abiotic stresses affecting soybean growth. Genetic improvement for salt tolerance is an effective way to protect soybean yield under salt stress conditions. Successful improvement of sa...Salt stress is one of the major abiotic stresses affecting soybean growth. Genetic improvement for salt tolerance is an effective way to protect soybean yield under salt stress conditions. Successful improvement of salt tolerance in soybean relies on identifying genetic variation that confers tolerance in soybean germplasm and subsequently incorporating these genetic resources into cultivars. In this review, we summarize the progress in genetic diversity and genetics of salt tolerance in soybean, which includes identifying genetic diversity for salt tolerant germplasm; mapping QTLs conferring salt tolerance; map-based cloning; and conducting genome-wide association study(GWAS) analysis in soybean. Future research avenues are also discussed, including high throughput phenotyping technology, the CRISPR/Cas9 Genome-Editing System, and genomic selection technology for molecular breeding of salt tolerance.展开更多
Heredity of high pure aluminum melts under different pulse electric field was investigated by means of repetitious remelt experiment. The results indicate that the genetic coefficient by measurement of grain size of c...Heredity of high pure aluminum melts under different pulse electric field was investigated by means of repetitious remelt experiment. The results indicate that the genetic coefficient by measurement of grain size of cast structure has a close relation with pulse voltage. Moreover, the hereditary law accords with the function of In = 1+ e^-an+β. The stability of genetic carrier (cluster) comprises in the competition between repetitious cooling and heating impulse and the effect of electric pulse modification.展开更多
The heredity of clusters in rapidly cooled(Zr_(50)Cu_(50))_(100-x)Al_x melts and its correlation with glass-forming ability(GFA)are studied via molecular dynamics simulations.Pair distribution function and the largest...The heredity of clusters in rapidly cooled(Zr_(50)Cu_(50))_(100-x)Al_x melts and its correlation with glass-forming ability(GFA)are studied via molecular dynamics simulations.Pair distribution function and the largest standard cluster(LSC)are adopted to characterize the local atomic structures in the(Zr_(50)Cu_(50))_(100-x)Al_(x)systems.The[12/555]icosahedra and their medium-range order(IMRO)play an important role in forming(Zr_(50)Cu_(50))_(100-x)Al_(x)metallic glasses(MGs).The fraction of[12/555],the number of IMRO,and the maximum size of IMRO in MGs increase significantly with increasing x.A tracking study further reveals that the configuration heredity of icosahedral clusters starts from supercooled liquids.No direct correlation exists between the GFA and the onset temperature of continuous or stated heredity.Instead,a larger hereditary supercooled degree of icosahedra matches with better GFA of Al-doped Zr_(50)Cu_(50)alloys.展开更多
The remarkable heredity of liquid aluminum modified by electric pulse (EP, EPM) has been uncovered. For better understanding from all aspects on the hereditary properties, the present research deals with the heredity ...The remarkable heredity of liquid aluminum modified by electric pulse (EP, EPM) has been uncovered. For better understanding from all aspects on the hereditary properties, the present research deals with the heredity destruction and the secondary EPM procedure. It is shown that the secondary EPM is capable of preventing the heredity reduction of EP-modified liquid aluminum, and that the final refining effect has a close relationship with technique parameters of the secondary EPM. Furthermore, at a certain superheated temperature depending on the initial EPM technique parameters, the heredity relationship of EP-modified liquid aluminum can be cut off during remelting. High temperature X-ray diffraction combining with the DSC tests also indicates that the EP-induced structure changes have almost disappeared at an elevated remelting temperature.展开更多
AIM: To investigate whether a fuzzy logic model could predict colorectal cancer (CRC) risk engendered by smoking in hereditary non-polyposis colorectal cancer (HNPCC) patients. METHODS: Three hundred and forty H...AIM: To investigate whether a fuzzy logic model could predict colorectal cancer (CRC) risk engendered by smoking in hereditary non-polyposis colorectal cancer (HNPCC) patients. METHODS: Three hundred and forty HNPCC mismatch repair (MMR) mutation carriers from the Creighton University Hereditary Cancer Institute Registry were selected for modeling. Age-dependent curves were generated to elucidate the joint effects between gene mutation (hMLH1 or hMSH2), gender, and smoking status on the probability of developing CRC. RESULTS: Smoking significantly increased CRC risk in male hMSH2 mutation carriers (P 〈 0.05). hMLH1 mutations augmented CRC risk relative to hMSH2 mutation carriers for males (P 〈 0.05). Males had a significantly higher risk of CRC than females for hMLH1 non smokers (P 〈 0.05), hMLH1 smokers (P 〈 0.1) and hMSH2 smokers (P 〈 0.1). Smoking promoted CRC in a dose-dependent manner in hMSH2 in males (P 〈 0.05). Females with hMSH2 mutations and both sexes with the hMLH1 groups only demonstrated a smoking effect after an extensive smoking history (P 〈 0.05). CONCLUSION: CRC promotion by smoking in HNPCC patients is dependent on gene mutation, gender and age. These data demonstrate that fuzzy modeling may enable formulation of clinical risk scores, thereby allowing individualization of CRC prevention strategies.展开更多
Spotted leaf(spl)mutant is a type of leaf lesion mimic mutants in plants.We obtained some lesion mimic mutants from ethyl methane sulfonate(EMS)-mutagenized wheat(Triticum aestivum L.)cultivar Guomai 301(wild type,WT)...Spotted leaf(spl)mutant is a type of leaf lesion mimic mutants in plants.We obtained some lesion mimic mutants from ethyl methane sulfonate(EMS)-mutagenized wheat(Triticum aestivum L.)cultivar Guomai 301(wild type,WT),and one of them was named as white stripe leaf(wsl)mutant because of the white stripes on its leaves.Here we report the heredity and gene mapping of this novel wheat mutant wsl.There are many small scattered white stripes on the leaves of wsl throughout its whole growth period.As the plants grew,the white stripes became more severe and the necrotic area expanded.The mutant wsl grew only weakly before the jointing stage and gradually recovered after jointing.The length and width of the flag leaf,spike number per plant and thousand-grain weight of wsl were significantly lower than those of the WT.Genetic analysis indicated that the trait of white stripe leaf was controlled by a recessive gene locus,named as wsl,which was mapped on the short arm of chromosome 6 B by SSR marker assay.Four SSR markers in the F2 population of wsl×CS were linked to wsl in the order of Xgpw1079–Xwmc104–Xgwm508-wsl–Xgpw7651 at 7.1,5.2,8.7,and 4.4 c M,respectively and three SSR markers in the F2 population of wsl×Jimai 22 were linked to wsl in the order of Xgwm508–Xwmc494–Xgwm518-wsl at 3.5,1.6 and 8.2 c M,respectively.In comparison to the reference genome sequence of Chinese Spring(CS),wsl is located in a 91-Mb region from 88 Mb(Xgwm518)to 179 Mb(Xgpw7651)on chromosome 6 BS.Mutant wsl is a novel germplasm for studying the molecular mechanism of wheat leaf development.展开更多
Heredity of microstructure in AlTiC master alloy, grain refiners, was analyzed. It is found that, for morphologies and distributions of TiC particles, there are visible heredity which originates from raw materials or ...Heredity of microstructure in AlTiC master alloy, grain refiners, was analyzed. It is found that, for morphologies and distributions of TiC particles, there are visible heredity which originates from raw materials or processing methods of Al melt, and will ultimately be transferred to the solid state structure through the melt stage, and this phenomenon can cause hereditary influences on refinement: formation of chain like TiC morphology results in rapid refinement fading behavior; distribution of TiC along grain boundaries greatly reduces refinement efficiency. Controlling of structural heredity through proper selections of raw materials and processing parameters is of great importance in obtaining ideal microstructures and improving refinement behaviors of AlTiC master alloys.展开更多
Macroscopic texture and microscopic orientation in hot-rolled and annealed sheets of nonoriented electrical steel were studied by XRD and EBSD techniques. The microstructure of hot-rolled and annealed samples was stud...Macroscopic texture and microscopic orientation in hot-rolled and annealed sheets of nonoriented electrical steel were studied by XRD and EBSD techniques. The microstructure of hot-rolled and annealed samples was studied by OM. Experimental results indicate that a strong heredity is observed in texture evolution between hot-rolled texture and annealed texture. Typical elements have a large effect on the recrystallization microstructure and texture distribution. The texture distribution through thickness is highly affected by recrystallization in hot rolled sheets. The recrystallization is boosted by Si and Al. Goss grains originate from cracked initial 〈100〉 columnar grains. {110}〈112〉, {112}〈111〉 and {111}〈112〉 grains are related to Goss grains. In subsurface lay of hot rolled sheets, Al can strengthen Goss texture and weaken copper-type texture. {112}〈111〉 texture and {110}〈112〉 texture are strengthened by Si. In the central layers, {100}〈001〉 texture and {111}〈121〉 texture are weakened by Al. {100}〈011〉 texture is increased by Al. Si can increase the proportion of γ-fiber texture and decrease that of {100}〈011〉 texture. In annealed texture, {100}〈001〉 texture and Goss texture are decreased by Al and Si. γ-fiber texture is increased by Si and {111}〈121〉 texture is preferentially increased by Al. The recrystallized grain size is increased and iron loss of annealed sheets is reduced by Al and Si, which means that the magnetic properties are optimized by the Al and Si content.展开更多
Through the polyacrylamide gel clectrophoresis analysis of thirty-two needle samples of ninty-years old pinus koraiensis in Harbin, seven typies of zone and distribution of the zone frequency, and some objective fact ...Through the polyacrylamide gel clectrophoresis analysis of thirty-two needle samples of ninty-years old pinus koraiensis in Harbin, seven typies of zone and distribution of the zone frequency, and some objective fact of heredity and variation were determined. These informations can be used as reference materials in the research of heredity and variation of pinus koraiensis.展开更多
A new concept of undercooling heredity is developed to evaluate the undercooling ability in a non catalytic nucleation coated mould, where alloy melts were highly undercooled previously. Before the heredity experiment...A new concept of undercooling heredity is developed to evaluate the undercooling ability in a non catalytic nucleation coated mould, where alloy melts were highly undercooled previously. Before the heredity experiment a non catalytic nucleation composite glass lined coating (B F) was prepared on the inner surface of mould and the Cu 70 Ni 30 alloy was selected to perform undercooling experiment in the B F non catalytic coating mould. Its ratio of undercooling heredity was 0.76. The results prove that the B F coating is an ideal non catalytic media for purified Cu 70 Ni 30 alloy melts due to its small contact angle between the melt and coating layer. Considering that various microstructures form under different undercoolings, two critical undercoolings, Δ T 1 and Δ T 2, and their corresponding microstructures of Cu 70 Ni 30 alloy are well defined. Moreover, it is found that the manned trigging solidification in the non catalytic coating mould could be used to get directional undercooling dendrite structure while the melt undercooling is larger than the critical undercooling Δ T 2.展开更多
Bruchid is a serious insect pest of mungbean [Vigna radiata (L.) Wilczek] and can inflict serious loss. A resistant variety from India, V2709, was crossed with a susceptible variety, Zhonglti 1, from the World Veget...Bruchid is a serious insect pest of mungbean [Vigna radiata (L.) Wilczek] and can inflict serious loss. A resistant variety from India, V2709, was crossed with a susceptible variety, Zhonglti 1, from the World Vegetable Center, Asian Vegetable Research and Development Center (AVRDC). Segregation of the F2, BC1F1, and F3 populations showed that bruchid resistance of V2709 is controlled by a single dominant locus. To find molecular marker linked with the resistant locus, 63 randomly amplified polymorphic DNA markers and 113 sets of SSR/STS primers were used in a bulked segregant analysis. Two of the markers, OPC-06 and STSbr2, were found to be linked with the locus (named as Br2). Further analysis suggested that the genetic distances between these two markers and Br2 were 11.0 and 5.8 cM, respectively.展开更多
The chloroplast DNA (cpDNA) and mitochondrial DNA (mtDNA) of 16 Populus species (Section Leuce) and their F1 generation were detected using PCR-RFLP technique. The results show that cpDNA in the F1 generation of...The chloroplast DNA (cpDNA) and mitochondrial DNA (mtDNA) of 16 Populus species (Section Leuce) and their F1 generation were detected using PCR-RFLP technique. The results show that cpDNA in the F1 generation of 22 hybrid combinations was inherited maternally, which supported the conclusions of the study of plasmid cytology. The mtDNA fragments amplified by PCR were consistent with the restriction maps in all hybrid combinations and no polymorphism was detected, indicating that the Section Leuce is highly conserved in mitochondrial gene sequences. These results provided direct evidence of maternal chloroplast inheritance in Populus tomentosa, P. bolleana, P. davidiana, P. adenopoda, P. tomentosa × P. bolleana, P. alba × P. glandulosa and P. alba × P. tomentosa.展开更多
The association between nicotine dependence and affective disorders, particularly major depressive disorder (MDD), is well known with high prevalence rates being reported for smokers. The reason for this association i...The association between nicotine dependence and affective disorders, particularly major depressive disorder (MDD), is well known with high prevalence rates being reported for smokers. The reason for this association is not clear, but, it has been argued that smoking may help individuals to cope with stress or medicate depressed mood. Smoking cessation programs are useful in helping smokers to quit, but smoking is a very difficult addiction to break, especially for people suffering from depression, and the need for novel and effective approaches to smoking cessation interventions for this special population is unquestionable. The e-cigarette is a battery-powered electronic nicotine delivery device (ENDD), which may help smokers to remain abstinent during their quit attempt. Here, we report for the first time objective measures of smoking cessation in two heavy smokers, suffering from depression, who experimented the e-cigarette.展开更多
Hereditary is one of the key risk factors of the Parkinson’s disease (PD) and children of individuals with the Parkinson’s carry a two-fold risk for the disease. In this article, chance of developing the Parkinson’...Hereditary is one of the key risk factors of the Parkinson’s disease (PD) and children of individuals with the Parkinson’s carry a two-fold risk for the disease. In this article, chance of developing the Parkinson’s disease is estimated for an individual in five types of families. That is, families with negative history of the PD (I), families with positive history where neither one of the parents (II), one of the parents (III-IV), or both parents (V) are diagnosed with the disease. After a sophisticated modeling, Maximum Likelihood and Bayesian Approach are used to estimate the chance of developing the Parkinson’s in the five mentioned family types. It is extremely important knowing such probabilities as the individual can take precautionary measures to defy the odds. While many physicians have provided medical opinions on chance of developing the PD, our study is one of the first to provide statistical modeling and analysis with real data to support the conclusions.展开更多
AIM: To ultrasonographicaly evaluate the acute effects of smoking on gallbladder contraction and refilling in chronic smokers and nonsmokers.METHODS: Fifteen chronic smokers (21-30 years old) and fifteen nonsmokers (2...AIM: To ultrasonographicaly evaluate the acute effects of smoking on gallbladder contraction and refilling in chronic smokers and nonsmokers.METHODS: Fifteen chronic smokers (21-30 years old) and fifteen nonsmokers (21-35 years old) participated in this study. Chronic smokers were selected among the volunteers who had been smoking for at least 5 years and 10 cigarettes per day (mean 17.5/d). Examinations were performed in two separate days. In the fi rst day, basal gallbladder (GB) volumes of volunteers were measured after 8-h fasting. After the examinations, participants had a meal containing at least 30-40 gram fat. Gallbladder volume was assessed at 5, 15, 30, 60, 120 and 180 min after the meal. In the second day, participants smoked 2 cigarettes after 8-h fasting. Then, they had the same meal, and gallbladder measurements were repeated at the same time points. Same procedures were applied to both groups. RESULTS: The mean starving GB volumes were 23.3 ± 3.3 mL in the fi rst day, 21.9 ± 3.0 mL in the second day in nonsmoker group and 18.3 ± 3.0 mL in the fi rst day, 19.5 ± 2.8 mL in second day in smoker group. There was no significant difference between starving GB volumes. We did not fi nd any signifi cant difference between the GB volumes measured at 5, 15, 30, 60, 120 and 180 min in the fi rst and second days in nonsmoker group. In smokers, post cigarette GB volume was found significantly higher at 5, 15 and 30 min which corresponded to GB contraction phase (P < 0.05). Control GB volume measurements were not signifi cantly different between the two groups. Post-smoking GB volumes were also not signifi cantly different between the two groups.CONCLUSION: Smoking prolongs the maximal GB emptying time both in smokers and in nonsmokers though it is not signifi cant. It delays GB contraction inchronic smokers and causes a signifi cant decrease in GB emptying volume. Smoking causes no signifi cant delay in GB refi lling in both smokers and nonsmokers. These effects of smoking observed in acute phase result in bile stasis in GB. Bile stasis is the underlying cause of most GB disorders in chronic process.展开更多
With the implementation of tobacco control policies and increasing publicity year by year,smokers have acquired more information and knowledge through various channels about the harmful effects of smoking.As a result,...With the implementation of tobacco control policies and increasing publicity year by year,smokers have acquired more information and knowledge through various channels about the harmful effects of smoking.As a result,more smokers have developed a desire to quit smoking and have begun to try to quit.展开更多
文摘[Objective]This paper aims to study the heredity and parental correlation of the oil content of the beginning of the generation at highoil content soybean.[Methods]Seven high yield or high-oil content soybean are selected and eight crosses are made according to the NCII design.[Results]The variation of oil content in F5 relates with the difference between parents.The more the differences between both parents have,the more variations of the oil content of F5 become.When the oil content of both parents are high,and the maturating time of them are very different,the probability of high-oil plant in F5 derived from these cross are high.The oil content of F5 generation has negative correlation with the different between both parents and has positive correlation with the oil content of male parent and significant positive correlation with the oil content of female parent and mid-parent.[Conclusions]This study result provide reference for the seedling of High-oil Content Soybean.
基金Item Sponsored by National Natural Science Foundation of China(50174028and50674054)
文摘The heredity of aluminum melt under the action of pulse electric field was investigated by means of the remelt experiment. A new hereditary criterion under this condition was proposed; in the meantime, the differential transferability of genetic carrier in activated melt among filial generations was validated with the aid of DSC.
基金This project was supported by the National Natural Science Foundation of China (60364001), the Shandong ProvincialNatural Science Foundation of China (Y2004A04) and Fujian Provincial Education Foundation of China(JA04268).
文摘Using S-rough sets, this paper gives the concepts off-heredity knowledge and its heredity coefficient, and f-variation coefficient of knowledge; presents the theorem of f-attribute dependence of variation coefficient and the relation theorem of heredity-variation. The attribute dependence of f-variation coefficient and the relation of heredity-variation are important characteristics of S-rough sets. From such discussion, this paper puts forward the heredity mining off-knowledge and the algorithm of heredity mining, also gives its relative application.
文摘Several risk factors,which include heredity,ultra-violet (UV) light and chronic inflammation,contribute to pterygium development.However,there is no report integrating these factors in the pathogenesis of pterygium.The aim of this review is to describe the connection between heredity,UV,and inflammation in pterygium development.Existing reports indicate that sunlight exposure is the main factor in pterygium occurrence by inducing growth factor production or chronic inflammation or DNA damage.Heredity may be a factor.Our studies on factors in pterygium occurrence and recurrence identify that heredity is crucial for pterygium to develop,and that sunlight is only a trigger,and that chronic inflammation promotes pterygium enlargement.We propose that genetic factors may interfere with the control of fibrovascular proliferation while UV light or(sunlight)most likely only triggers pterygium development by inducing growth factors which promote vibrant fibrovascular proliferation in predisposed individuals.It also just triggers inflammation and collagenolysis,which may be promoters of the enlargement of the fibrovascular mass.Pterygium probably occurs in the presence of exuberant collagen production and profuse neovascularisation.
基金supported by the National Natural Science Foundation of China (31401407)
文摘Salt stress is one of the major abiotic stresses affecting soybean growth. Genetic improvement for salt tolerance is an effective way to protect soybean yield under salt stress conditions. Successful improvement of salt tolerance in soybean relies on identifying genetic variation that confers tolerance in soybean germplasm and subsequently incorporating these genetic resources into cultivars. In this review, we summarize the progress in genetic diversity and genetics of salt tolerance in soybean, which includes identifying genetic diversity for salt tolerant germplasm; mapping QTLs conferring salt tolerance; map-based cloning; and conducting genome-wide association study(GWAS) analysis in soybean. Future research avenues are also discussed, including high throughput phenotyping technology, the CRISPR/Cas9 Genome-Editing System, and genomic selection technology for molecular breeding of salt tolerance.
基金Item Sponsored by National Natural Science Foundation of China (50174028 ,50674054)
文摘Heredity of high pure aluminum melts under different pulse electric field was investigated by means of repetitious remelt experiment. The results indicate that the genetic coefficient by measurement of grain size of cast structure has a close relation with pulse voltage. Moreover, the hereditary law accords with the function of In = 1+ e^-an+β. The stability of genetic carrier (cluster) comprises in the competition between repetitious cooling and heating impulse and the effect of electric pulse modification.
基金the National Natural Science Foundation of China(Grant No.51701071)the Natural Science Foundation of Hunan Province,China(Grant Nos.2018JJ3100 and 2018JJ2078)the Project of the Hunan Educational Department,China(Grant No.19B122)。
文摘The heredity of clusters in rapidly cooled(Zr_(50)Cu_(50))_(100-x)Al_x melts and its correlation with glass-forming ability(GFA)are studied via molecular dynamics simulations.Pair distribution function and the largest standard cluster(LSC)are adopted to characterize the local atomic structures in the(Zr_(50)Cu_(50))_(100-x)Al_(x)systems.The[12/555]icosahedra and their medium-range order(IMRO)play an important role in forming(Zr_(50)Cu_(50))_(100-x)Al_(x)metallic glasses(MGs).The fraction of[12/555],the number of IMRO,and the maximum size of IMRO in MGs increase significantly with increasing x.A tracking study further reveals that the configuration heredity of icosahedral clusters starts from supercooled liquids.No direct correlation exists between the GFA and the onset temperature of continuous or stated heredity.Instead,a larger hereditary supercooled degree of icosahedra matches with better GFA of Al-doped Zr_(50)Cu_(50)alloys.
基金supported financially by the National Natural Science Foundation of China(No.51074087)the Liaoning BaiQianWan Talents Program(No.2010921096)
文摘The remarkable heredity of liquid aluminum modified by electric pulse (EP, EPM) has been uncovered. For better understanding from all aspects on the hereditary properties, the present research deals with the heredity destruction and the secondary EPM procedure. It is shown that the secondary EPM is capable of preventing the heredity reduction of EP-modified liquid aluminum, and that the final refining effect has a close relationship with technique parameters of the secondary EPM. Furthermore, at a certain superheated temperature depending on the initial EPM technique parameters, the heredity relationship of EP-modified liquid aluminum can be cut off during remelting. High temperature X-ray diffraction combining with the DSC tests also indicates that the EP-induced structure changes have almost disappeared at an elevated remelting temperature.
基金Supported by a grant from the American College of Gastroenterology
文摘AIM: To investigate whether a fuzzy logic model could predict colorectal cancer (CRC) risk engendered by smoking in hereditary non-polyposis colorectal cancer (HNPCC) patients. METHODS: Three hundred and forty HNPCC mismatch repair (MMR) mutation carriers from the Creighton University Hereditary Cancer Institute Registry were selected for modeling. Age-dependent curves were generated to elucidate the joint effects between gene mutation (hMLH1 or hMSH2), gender, and smoking status on the probability of developing CRC. RESULTS: Smoking significantly increased CRC risk in male hMSH2 mutation carriers (P 〈 0.05). hMLH1 mutations augmented CRC risk relative to hMSH2 mutation carriers for males (P 〈 0.05). Males had a significantly higher risk of CRC than females for hMLH1 non smokers (P 〈 0.05), hMLH1 smokers (P 〈 0.1) and hMSH2 smokers (P 〈 0.1). Smoking promoted CRC in a dose-dependent manner in hMSH2 in males (P 〈 0.05). Females with hMSH2 mutations and both sexes with the hMLH1 groups only demonstrated a smoking effect after an extensive smoking history (P 〈 0.05). CONCLUSION: CRC promotion by smoking in HNPCC patients is dependent on gene mutation, gender and age. These data demonstrate that fuzzy modeling may enable formulation of clinical risk scores, thereby allowing individualization of CRC prevention strategies.
基金supported by the National Natural Science Foundation of China(NSFC,31571646)the Science and Technology Project in Henan Province,China(182102110147)。
文摘Spotted leaf(spl)mutant is a type of leaf lesion mimic mutants in plants.We obtained some lesion mimic mutants from ethyl methane sulfonate(EMS)-mutagenized wheat(Triticum aestivum L.)cultivar Guomai 301(wild type,WT),and one of them was named as white stripe leaf(wsl)mutant because of the white stripes on its leaves.Here we report the heredity and gene mapping of this novel wheat mutant wsl.There are many small scattered white stripes on the leaves of wsl throughout its whole growth period.As the plants grew,the white stripes became more severe and the necrotic area expanded.The mutant wsl grew only weakly before the jointing stage and gradually recovered after jointing.The length and width of the flag leaf,spike number per plant and thousand-grain weight of wsl were significantly lower than those of the WT.Genetic analysis indicated that the trait of white stripe leaf was controlled by a recessive gene locus,named as wsl,which was mapped on the short arm of chromosome 6 B by SSR marker assay.Four SSR markers in the F2 population of wsl×CS were linked to wsl in the order of Xgpw1079–Xwmc104–Xgwm508-wsl–Xgpw7651 at 7.1,5.2,8.7,and 4.4 c M,respectively and three SSR markers in the F2 population of wsl×Jimai 22 were linked to wsl in the order of Xgwm508–Xwmc494–Xgwm518-wsl at 3.5,1.6 and 8.2 c M,respectively.In comparison to the reference genome sequence of Chinese Spring(CS),wsl is located in a 91-Mb region from 88 Mb(Xgwm518)to 179 Mb(Xgpw7651)on chromosome 6 BS.Mutant wsl is a novel germplasm for studying the molecular mechanism of wheat leaf development.
文摘Heredity of microstructure in AlTiC master alloy, grain refiners, was analyzed. It is found that, for morphologies and distributions of TiC particles, there are visible heredity which originates from raw materials or processing methods of Al melt, and will ultimately be transferred to the solid state structure through the melt stage, and this phenomenon can cause hereditary influences on refinement: formation of chain like TiC morphology results in rapid refinement fading behavior; distribution of TiC along grain boundaries greatly reduces refinement efficiency. Controlling of structural heredity through proper selections of raw materials and processing parameters is of great importance in obtaining ideal microstructures and improving refinement behaviors of AlTiC master alloys.
基金Funded by the Fundamental Research Funds for the Central Universities(TP-A3)(No.:FRF-TP-15-063A3)
文摘Macroscopic texture and microscopic orientation in hot-rolled and annealed sheets of nonoriented electrical steel were studied by XRD and EBSD techniques. The microstructure of hot-rolled and annealed samples was studied by OM. Experimental results indicate that a strong heredity is observed in texture evolution between hot-rolled texture and annealed texture. Typical elements have a large effect on the recrystallization microstructure and texture distribution. The texture distribution through thickness is highly affected by recrystallization in hot rolled sheets. The recrystallization is boosted by Si and Al. Goss grains originate from cracked initial 〈100〉 columnar grains. {110}〈112〉, {112}〈111〉 and {111}〈112〉 grains are related to Goss grains. In subsurface lay of hot rolled sheets, Al can strengthen Goss texture and weaken copper-type texture. {112}〈111〉 texture and {110}〈112〉 texture are strengthened by Si. In the central layers, {100}〈001〉 texture and {111}〈121〉 texture are weakened by Al. {100}〈011〉 texture is increased by Al. Si can increase the proportion of γ-fiber texture and decrease that of {100}〈011〉 texture. In annealed texture, {100}〈001〉 texture and Goss texture are decreased by Al and Si. γ-fiber texture is increased by Si and {111}〈121〉 texture is preferentially increased by Al. The recrystallized grain size is increased and iron loss of annealed sheets is reduced by Al and Si, which means that the magnetic properties are optimized by the Al and Si content.
文摘Through the polyacrylamide gel clectrophoresis analysis of thirty-two needle samples of ninty-years old pinus koraiensis in Harbin, seven typies of zone and distribution of the zone frequency, and some objective fact of heredity and variation were determined. These informations can be used as reference materials in the research of heredity and variation of pinus koraiensis.
文摘A new concept of undercooling heredity is developed to evaluate the undercooling ability in a non catalytic nucleation coated mould, where alloy melts were highly undercooled previously. Before the heredity experiment a non catalytic nucleation composite glass lined coating (B F) was prepared on the inner surface of mould and the Cu 70 Ni 30 alloy was selected to perform undercooling experiment in the B F non catalytic coating mould. Its ratio of undercooling heredity was 0.76. The results prove that the B F coating is an ideal non catalytic media for purified Cu 70 Ni 30 alloy melts due to its small contact angle between the melt and coating layer. Considering that various microstructures form under different undercoolings, two critical undercoolings, Δ T 1 and Δ T 2, and their corresponding microstructures of Cu 70 Ni 30 alloy are well defined. Moreover, it is found that the manned trigging solidification in the non catalytic coating mould could be used to get directional undercooling dendrite structure while the melt undercooling is larger than the critical undercooling Δ T 2.
基金supported by the National Natural Science Foundation of China(30170635)Crop Germplasm Protection,China(NB04-22-12)National Facilities and Information Infrastructure for Scinece and Technology,China(2004DKA30380-08,National Key Technology Support Plan,China(2006BAD02B08),Science and Technology of Agricultural Vocation,China(nyhyzx07-017).
文摘Bruchid is a serious insect pest of mungbean [Vigna radiata (L.) Wilczek] and can inflict serious loss. A resistant variety from India, V2709, was crossed with a susceptible variety, Zhonglti 1, from the World Vegetable Center, Asian Vegetable Research and Development Center (AVRDC). Segregation of the F2, BC1F1, and F3 populations showed that bruchid resistance of V2709 is controlled by a single dominant locus. To find molecular marker linked with the resistant locus, 63 randomly amplified polymorphic DNA markers and 113 sets of SSR/STS primers were used in a bulked segregant analysis. Two of the markers, OPC-06 and STSbr2, were found to be linked with the locus (named as Br2). Further analysis suggested that the genetic distances between these two markers and Br2 were 11.0 and 5.8 cM, respectively.
基金the National Science Foundation of China (Grant Nos. 30771747 and 30640036)the Beijing Natural Science Foundation (No. 6042020)+1 种基金the research projects supported by the Hebei Education Department (No. Z2010102)the Baoding University (No. 2010Z02)
文摘The chloroplast DNA (cpDNA) and mitochondrial DNA (mtDNA) of 16 Populus species (Section Leuce) and their F1 generation were detected using PCR-RFLP technique. The results show that cpDNA in the F1 generation of 22 hybrid combinations was inherited maternally, which supported the conclusions of the study of plasmid cytology. The mtDNA fragments amplified by PCR were consistent with the restriction maps in all hybrid combinations and no polymorphism was detected, indicating that the Section Leuce is highly conserved in mitochondrial gene sequences. These results provided direct evidence of maternal chloroplast inheritance in Populus tomentosa, P. bolleana, P. davidiana, P. adenopoda, P. tomentosa × P. bolleana, P. alba × P. glandulosa and P. alba × P. tomentosa.
文摘The association between nicotine dependence and affective disorders, particularly major depressive disorder (MDD), is well known with high prevalence rates being reported for smokers. The reason for this association is not clear, but, it has been argued that smoking may help individuals to cope with stress or medicate depressed mood. Smoking cessation programs are useful in helping smokers to quit, but smoking is a very difficult addiction to break, especially for people suffering from depression, and the need for novel and effective approaches to smoking cessation interventions for this special population is unquestionable. The e-cigarette is a battery-powered electronic nicotine delivery device (ENDD), which may help smokers to remain abstinent during their quit attempt. Here, we report for the first time objective measures of smoking cessation in two heavy smokers, suffering from depression, who experimented the e-cigarette.
文摘Hereditary is one of the key risk factors of the Parkinson’s disease (PD) and children of individuals with the Parkinson’s carry a two-fold risk for the disease. In this article, chance of developing the Parkinson’s disease is estimated for an individual in five types of families. That is, families with negative history of the PD (I), families with positive history where neither one of the parents (II), one of the parents (III-IV), or both parents (V) are diagnosed with the disease. After a sophisticated modeling, Maximum Likelihood and Bayesian Approach are used to estimate the chance of developing the Parkinson’s in the five mentioned family types. It is extremely important knowing such probabilities as the individual can take precautionary measures to defy the odds. While many physicians have provided medical opinions on chance of developing the PD, our study is one of the first to provide statistical modeling and analysis with real data to support the conclusions.
文摘AIM: To ultrasonographicaly evaluate the acute effects of smoking on gallbladder contraction and refilling in chronic smokers and nonsmokers.METHODS: Fifteen chronic smokers (21-30 years old) and fifteen nonsmokers (21-35 years old) participated in this study. Chronic smokers were selected among the volunteers who had been smoking for at least 5 years and 10 cigarettes per day (mean 17.5/d). Examinations were performed in two separate days. In the fi rst day, basal gallbladder (GB) volumes of volunteers were measured after 8-h fasting. After the examinations, participants had a meal containing at least 30-40 gram fat. Gallbladder volume was assessed at 5, 15, 30, 60, 120 and 180 min after the meal. In the second day, participants smoked 2 cigarettes after 8-h fasting. Then, they had the same meal, and gallbladder measurements were repeated at the same time points. Same procedures were applied to both groups. RESULTS: The mean starving GB volumes were 23.3 ± 3.3 mL in the fi rst day, 21.9 ± 3.0 mL in the second day in nonsmoker group and 18.3 ± 3.0 mL in the fi rst day, 19.5 ± 2.8 mL in second day in smoker group. There was no significant difference between starving GB volumes. We did not fi nd any signifi cant difference between the GB volumes measured at 5, 15, 30, 60, 120 and 180 min in the fi rst and second days in nonsmoker group. In smokers, post cigarette GB volume was found significantly higher at 5, 15 and 30 min which corresponded to GB contraction phase (P < 0.05). Control GB volume measurements were not signifi cantly different between the two groups. Post-smoking GB volumes were also not signifi cantly different between the two groups.CONCLUSION: Smoking prolongs the maximal GB emptying time both in smokers and in nonsmokers though it is not signifi cant. It delays GB contraction inchronic smokers and causes a signifi cant decrease in GB emptying volume. Smoking causes no signifi cant delay in GB refi lling in both smokers and nonsmokers. These effects of smoking observed in acute phase result in bile stasis in GB. Bile stasis is the underlying cause of most GB disorders in chronic process.
基金supported by National Key R&D Program of China[2017YFC1309400]。
文摘With the implementation of tobacco control policies and increasing publicity year by year,smokers have acquired more information and knowledge through various channels about the harmful effects of smoking.As a result,more smokers have developed a desire to quit smoking and have begun to try to quit.