Background and Aims: Mesocentrotus nudus is commercially harvested from shallow rocky bottoms in northern Japan. The gonads are targeted as an edible product. The objective of this study was to identify odor-active vo...Background and Aims: Mesocentrotus nudus is commercially harvested from shallow rocky bottoms in northern Japan. The gonads are targeted as an edible product. The objective of this study was to identify odor-active volatile organic compounds (VOCs) from the gonads of adult M. nudus collected at a fishing ground in Miyagi Prefecture, Tohoku, Japan. Methods and Results: Gas chromatography-mass spectrometry analysis and gas chromatography-sniffing techniques identified 42 compounds categorized as alcohols, aldehydes, aromatic hydrocarbons, esters, halomethanes, hydrocarbons, ketones, sulfur-containing compounds, and nitrogen-containing compounds. GC-sniffing analysis characterized four compounds with preferable odors of sea urchin gonads;limonene, propyl acetate, acetone, dibromochloromethane. On the other hand, the analysis characterized three compounds with unpreferable odors;methyl mercaptane, dimethyl sulfide, and s-methyl thioacetate. Several VOCs from the gonads were derived from seaweeds, terrestrial plants, and fish flesh as food because M. nudus is omnivorous. Conclusion: This is the first study to identify VOCs from edible sea urchin gonads in the wild in Japan. These VOC data comprise a typical standard in order to evaluate a higher quality of sea urchin gonads.展开更多
The present study aims to evaluate in rats the activity changes associated to treatments with D2-like receptor agonists using a simple behavioral procedure. Rats receiving a single dose of 1 mg/kg quinpirole or vehicl...The present study aims to evaluate in rats the activity changes associated to treatments with D2-like receptor agonists using a simple behavioral procedure. Rats receiving a single dose of 1 mg/kg quinpirole or vehicle were scored for 6 spontaneous behaviors at different post-injection times. In each time point, the animals were placed in testing cages for 12 min and video-recorded during the last 2 min. The number of forelimb steps and the time spent sniffing were significantly increased by 15 min post-injection in the quinpirole group. Forelimb steps remained increased for at least 24 h. Scores of time spent sniffing, as well as time inactive and number of hindlimb steps appeared greatly altered at 90 and 180 min, but not at later time points. By 48 h, no differences between control and quinpirole-treated rats were observed. In conclusion, the simple behavioral procedure here proposed—or adaptations of it—provides a sensitive test to evaluate the time course of the effects of D2-like receptor agonists on rat spontaneous activity. Additionally, this test takes into account context-dependent sensitization. It can be adapted to different treatment conditions. This methodology would be useful for the preclinical screening of D2-like receptor drugs, using reduced numbers of animals to test those doses and treatment schedules producing less side-effects.展开更多
To understand the characteristics of the wireless networks, the network usage data from wireless measurement tools are essential. The data collection is a process of collecting the network time-varying information in ...To understand the characteristics of the wireless networks, the network usage data from wireless measurement tools are essential. The data collection is a process of collecting the network time-varying information in standardized format and from standard interfaces. The characteristics include signal propagation, received signal quality, network traffic, active applications and mobility of the mobile terminal (MT). The purpose of the measurement is to collect vital data of the wireless network. There are several tools available for this purpose. The most widely used network measurement tools are client side measurement tool, Syslog, Simple Network Management protocol (SNMP), network sniffing, wireless sniffing. This paper discusses the different wireless measurement tools and their benefits and limitation these tools.展开更多
文摘Background and Aims: Mesocentrotus nudus is commercially harvested from shallow rocky bottoms in northern Japan. The gonads are targeted as an edible product. The objective of this study was to identify odor-active volatile organic compounds (VOCs) from the gonads of adult M. nudus collected at a fishing ground in Miyagi Prefecture, Tohoku, Japan. Methods and Results: Gas chromatography-mass spectrometry analysis and gas chromatography-sniffing techniques identified 42 compounds categorized as alcohols, aldehydes, aromatic hydrocarbons, esters, halomethanes, hydrocarbons, ketones, sulfur-containing compounds, and nitrogen-containing compounds. GC-sniffing analysis characterized four compounds with preferable odors of sea urchin gonads;limonene, propyl acetate, acetone, dibromochloromethane. On the other hand, the analysis characterized three compounds with unpreferable odors;methyl mercaptane, dimethyl sulfide, and s-methyl thioacetate. Several VOCs from the gonads were derived from seaweeds, terrestrial plants, and fish flesh as food because M. nudus is omnivorous. Conclusion: This is the first study to identify VOCs from edible sea urchin gonads in the wild in Japan. These VOC data comprise a typical standard in order to evaluate a higher quality of sea urchin gonads.
文摘The present study aims to evaluate in rats the activity changes associated to treatments with D2-like receptor agonists using a simple behavioral procedure. Rats receiving a single dose of 1 mg/kg quinpirole or vehicle were scored for 6 spontaneous behaviors at different post-injection times. In each time point, the animals were placed in testing cages for 12 min and video-recorded during the last 2 min. The number of forelimb steps and the time spent sniffing were significantly increased by 15 min post-injection in the quinpirole group. Forelimb steps remained increased for at least 24 h. Scores of time spent sniffing, as well as time inactive and number of hindlimb steps appeared greatly altered at 90 and 180 min, but not at later time points. By 48 h, no differences between control and quinpirole-treated rats were observed. In conclusion, the simple behavioral procedure here proposed—or adaptations of it—provides a sensitive test to evaluate the time course of the effects of D2-like receptor agonists on rat spontaneous activity. Additionally, this test takes into account context-dependent sensitization. It can be adapted to different treatment conditions. This methodology would be useful for the preclinical screening of D2-like receptor drugs, using reduced numbers of animals to test those doses and treatment schedules producing less side-effects.
文摘To understand the characteristics of the wireless networks, the network usage data from wireless measurement tools are essential. The data collection is a process of collecting the network time-varying information in standardized format and from standard interfaces. The characteristics include signal propagation, received signal quality, network traffic, active applications and mobility of the mobile terminal (MT). The purpose of the measurement is to collect vital data of the wireless network. There are several tools available for this purpose. The most widely used network measurement tools are client side measurement tool, Syslog, Simple Network Management protocol (SNMP), network sniffing, wireless sniffing. This paper discusses the different wireless measurement tools and their benefits and limitation these tools.