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Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior 被引量:1
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作者 Man Han Deyang Zeng +7 位作者 Wei Tan Xingxing Chen Shuyuan Bai Qiong Wu Yushan Chen Zhen Wei Yufei Mei Yan Zeng 《Neural Regeneration Research》 SCIE CAS 2025年第1期159-173,共15页
Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral response.Recent studies have shown that brain-derived neurotrophic factor expression in stressed mice ... Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral response.Recent studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and hippocampus.Determining how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress psychopathology.In this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of depression.We focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine circuit.We determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic system.Therefore,BDNF might be a biological indicator regulating stress-related processes in various brain regions. 展开更多
关键词 AMYGDALA chronic mild stress chronic social defeat stress corticolimbic system DEPRESSION HIPPOCAMPUS medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area
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Investigation of Coronavirus Deposition in Realistic Human Nasal Cavity and Impact of Social Distancing to Contain COVID-19:A Computational Fluid Dynamic Approach 被引量:1
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作者 Mohammad Zuber John Valerian Corda +8 位作者 Milad Ahmadi BSatish Shenoy Irfan Anjum Badruddin Ali E.Anqi Kamarul Arifin Ahmad S.M.Abdul Khader Leslie Lewis Mohammad Anas Khan Sarfaraz Kamangar 《Computer Modeling in Engineering & Sciences》 SCIE EI 2020年第12期1185-1199,共15页
The novel coronavirus responsible for COVID-19 has spread to several countries within a considerably short period.The virus gets deposited in the human nasal cavity and moves to the lungs that might be fatal.As per sa... The novel coronavirus responsible for COVID-19 has spread to several countries within a considerably short period.The virus gets deposited in the human nasal cavity and moves to the lungs that might be fatal.As per safety guidelines by theWorld Health Organization(WHO),social distancing has emerged as one of the major factors to avoid the spread of infection.However,different guidelines are being followed across the countries with regards to what should be the safe distance.Thus,the current work is an attempt to understand the virus deposition pattern in the realistic human nasal cavity and also to find the impact of distance that could be termed as a safety measure.This study is performed usingComputationalFluid Dynamics as a solution tool to investigate the impact of COVID-19 deposition(i)On a realistic 3D human upper airway model and(ii)2D social distancing protocol for a distance of 0.6,1.2,1.8,and 2.4 m.The results revealed that the regional deposition flux within the nasal cavity was predominantly observed in the external nasal cavity and nasopharyngeal section.Frequent flushing of these regions with saltwater substitutes can limit contamination in healthy individuals.The safe distancing limit estimated with 1 m/s airflow was about 1.8 m.The extensive deposition was observed for distances less than 1.8 m in this study,emphasizing the fact that social distancing advisories are not useful and do not take into account the external dynamics associated with airflow. 展开更多
关键词 COVID-19 upper respiratory tract virus deposition social distancing
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Investigation of the epidemiology,pathogenicity and immunogenicity of Bordetella bronchiseptica isolated from cats and dogs in China from 2021 to 2023 被引量:1
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作者 Qinghua Shang Wenhui Gao +7 位作者 Xiangting Zhang Jianqing Zhao Ying Wu Haoqi Li Ming Zhou Zhen F.Fu Chengguang Zhang Ling Zhao 《Animal Diseases》 CAS 2024年第3期156-172,共17页
Bordetella bronchiseptica(Bb)is recognized as a leading cause of respiratory diseases in dogs and cats.However,epidemiological data on Bb in dogs and cats in China are still limited,and there is no commercially availa... Bordetella bronchiseptica(Bb)is recognized as a leading cause of respiratory diseases in dogs and cats.However,epidemiological data on Bb in dogs and cats in China are still limited,and there is no commercially available vaccine.Live vaccines containing Bb that are widely used abroad are generally efective but can establish latency and potentially reactivate to cause illness in some immunodefcient vaccinated recipients,raising safety concerns.In this study,34 canine-derived and two feline-derived Bb strains were isolated from 1809 canine and 113 feline nasopharyngeal swab samples collected from eight provinces in China from 2021 to 2023.The PCR results showed that the percentage of positive Bb was 22.94%(441/1922),and more than 90%of the Bb isolates had four virulence factor-encoding genes(VFGs),namely,fhaB,prn,betA and dnt.All the isolated strains displayed a multidrug-resistant phenotype.The virulence of 10 Bb strains isolated from dogs with respiratory symptoms was tested in mice,and we found that eight isolates were highly virulent.Furthermore,the eight Bb isolates with high virulence were inactivated and intramuscularly injected into mice,and three Bb strains(WH1218,WH1203 and WH1224)with the best protective efcacy were selected.Dogs immunized with these three strains exhibited strong protection against challenge with the Bb feld strain WH1218.Ultimately,the WH1218 strain with the greatest protection in dogs was selected as the vaccine candidate.Dogs and cats that received a vaccine containing 109 CFU of the inactivated WH1218 strain showed complete protection against challenge with the Bb feld strain WH1218.This study revealed that Bb is an important pathogen that causes respiratory diseases in domestic dogs and cats in China,and all the isolates exhibited multidrug resistance.The present work contributes to the current understanding of the prevalence,antimicrobial resistance,and virulence genes of Bb in domestic dogs and cats.Additionally,our results suggest that the WH1218 strain is a promising candidate safe and efcacious inactivated Bb vaccine. 展开更多
关键词 Bordetella bronchiseptica Epidemiological investigation PATHOGENICITY IMMUNOGENICITY Inactivated vaccine
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Experimental investigation on coal pore-fracture variation and fractal characteristics synergistically affected by solvents for improving clean gas extraction 被引量:1
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作者 Feilin Han Sheng Xue +3 位作者 Chunshan Zheng Zhongwei Chen Guofu Li Bingyou Jiang 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第3期413-425,共13页
Chemical solvents instead of pure water being as hydraulic fracturing fluid could effectively increase permeability and improve clean methane extraction efficiency.However,pore-fracture variation features of lean coal... Chemical solvents instead of pure water being as hydraulic fracturing fluid could effectively increase permeability and improve clean methane extraction efficiency.However,pore-fracture variation features of lean coal synergistically affected by solvents have not been fully understood.Ultrasonic testing,nuclear magnetic resonance analysis,liquid phase mass spectrometry was adopted to comprehensively analyze pore-fracture change characteristics of lean coal treated by combined solvent(NMP and CS_(2)).Meanwhile,quantitative characterization of above changing properties was conducted using geometric fractal theory.Relationship model between permeability,fractal dimension and porosity were established.Results indicate that the end face fractures of coal are well developed after CS2and combined solvent treatments,of which,end face box-counting fractal dimensions range from 1.1227 to 1.4767.Maximum decreases in ultrasonic longitudinal wave velocity of coal affected by NMP,CS_(2)and combined solvent are 2.700%,20.521%,22.454%,respectively.Solvent treatments could lead to increasing amount of both mesopores and macropores.Decrease ratio of fractal dimension Dsis 0.259%–2.159%,while permeability increases ratio of NMR ranges from 0.1904 to 6.4486.Meanwhile,combined solvent could dissolve coal polar and non-polar small molecules and expand flow space.Results could provide reference for solvent selection and parameter optimization of permeability-enhancement technology. 展开更多
关键词 Clean gas extraction Chemical solvent Experimental investigation Fractal characteristics Pore fracture
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Integrated ribosome and proteome analyses reveal insights into sevoflurane-induced long-term social behavior and cognitive dysfunctions through ADNP inhibition in neonatal mice 被引量:1
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作者 Li-Rong Liang Bing Liu +9 位作者 Shu-Hui Cao You-Yi Zhao Tian Zeng Mei-Ting Zhai Ze Fan Dan-Yi He San-Xin Ma Xiao-Tong Shi Yao Zhang Hui Zhang 《Zoological Research》 SCIE CSCD 2024年第3期663-678,共16页
A growing number of studies have demonstrated that repeated exposure to sevoflurane during development results in persistent social abnormalities and cognitive impairment.Davunetide,an active fragment of the activity-... A growing number of studies have demonstrated that repeated exposure to sevoflurane during development results in persistent social abnormalities and cognitive impairment.Davunetide,an active fragment of the activity-dependent neuroprotective protein(ADNP),has been implicated in social and cognitive protection.However,the potential of davunetide to attenuate social deficits following sevoflurane exposure and the underlying developmental mechanisms remain poorly understood.In this study,ribosome and proteome profiles were analyzed to investigate the molecular basis of sevoflurane-induced social deficits in neonatal mice.The neuropathological basis was also explored using Golgi staining,morphological analysis,western blotting,electrophysiological analysis,and behavioral analysis.Results indicated that ADNP was significantly down-regulated following developmental exposure to sevoflurane.In adulthood,anterior cingulate cortex(ACC)neurons exposed to sevoflurane exhibited a decrease in dendrite number,total dendrite length,and spine density.Furthermore,the expression levels of Homer,PSD95,synaptophysin,and vglut2 were significantly reduced in the sevoflurane group.Patch-clamp recordings indicated reductions in both the frequency and amplitude of miniature excitatory postsynaptic currents(mEPSCs).Notably,davunetide significantly ameliorated the synaptic defects,social behavior deficits,and cognitive impairments induced by sevoflurane.Mechanistic analysis revealed that loss of ADNP led to dysregulation of Ca^(2+)activity via the Wnt/β-catenin signaling,resulting in decreased expression of synaptic proteins.Suppression of Wnt signaling was restored in the davunetide-treated group.Thus,ADNP was identified as a promising therapeutic target for the prevention and treatment of neurodevelopmental toxicity caused by general anesthetics.This study provides important insights into the mechanisms underlying social and cognitive disturbances caused by sevoflurane exposure in neonatal mice and elucidates the regulatory pathways involved. 展开更多
关键词 Davunetide SEVOFLURANE Abnormal social behaviors ADNP NEUROTOXICITY
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Mapping and measuring urban-rural inequalities in accessibility to social infrastructures 被引量:1
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作者 Chenmeng Guo Weiqi Zhou +1 位作者 Chuanbao Jing Dawa Zhaxi 《Geography and Sustainability》 CSCD 2024年第1期41-51,共11页
Equal access to social infrastructures is a fundamental prerequisite for sustainable development,but has long been a great challenge worldwide.Previous studies have primarily focused on the accessibility to social inf... Equal access to social infrastructures is a fundamental prerequisite for sustainable development,but has long been a great challenge worldwide.Previous studies have primarily focused on the accessibility to social infras-tructures in urban areas across various scales,with less attention to rural areas,where inequality can be more severe.Particularly,few have investigated the disparities of accessibility to social infrastructures between urban and rural areas.Here,using the Changsha-Zhuzhou-Xiangtan urban agglomeration,China,as an example,we investigated the inequality of accessibility in both urban and rural areas,and further compared the urban-rural difference.Accessibility was measured by travel time of residents to infrastructures.We selected four types of social infrastructures including supermarkets,bus stops,primary schools,and health care,which were funda-mentally important to both urban and rural residents.We found large disparities in accessibility between urban and rural areas,ranging from 20 min to 2 h.Rural residents had to spend one to two more hours to bus stops than urban residents,and 20 min more to the other three types of infrastructures.Furthermore,accessibility to multiple infrastructures showed greater urban-rural differences.Rural residents in more than half of the towns had no access to any infrastructure within 15 min,while more than 60%of the urban residents could access to all infrastructures within 15 min.Our results revealed quantitative accessibility gap between urban and rural areas and underscored the necessity of social infrastructures planning to address such disparities. 展开更多
关键词 ACCESSIBILITY social infrastructures Urban-rural difference INEQUALITY Regional sustainability
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Dysfunctional attitudes,social support,negative life events,and depressive symptoms in Chinese adolescents:A moderated mediation model 被引量:2
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作者 Teng-Fei Yu Li Liu +3 位作者 Lu-Ning Shang Fang-Fang Xu Zhi-Min Chen Li-Ju Qian 《World Journal of Psychiatry》 SCIE 2024年第11期1671-1680,共10页
BACKGROUND Depression is a prevalent psychological issue in adolescents that is significantly related to negative life events(NLEs)and dysfunctional attitudes.High levels of social support can significantly buffer NLE... BACKGROUND Depression is a prevalent psychological issue in adolescents that is significantly related to negative life events(NLEs)and dysfunctional attitudes.High levels of social support can significantly buffer NLEs’effect on depression.Currently,there is limited research on how social support moderates the relationship between NLEs,dysfunctional attitudes,and depression in adolescents in China.It is imperative to investigate this moderating effect to mitigate dysfunctional attitudes in adolescent undergoing depressive mood,ultimately enhancing their overall mental health.AIM To investigate the relationship and underlying mechanisms between specific dysfunctional attitudes,social support,and depression among Chinese adolescents.METHODS This is a cross-sectional study which selected five middle schools in Shandong Province for investigation in March 2022.Participants included 795 adolescents(49.87%male,mage=15.15,SD=1.84,age range=11-18 years old).All participants completed the Dysfunctional Attitude Scale,Adolescent Life Event Scale,Beck Depression Inventory,and Social Support Rating Scale.A moderated mediation model was conducted to examine the relationship between specific dysfunctional attitudes,social support,and depression.RESULTS Results indicated that NLEs affected depression through the mediating role of specific dysfunctional attitudes(autonomy attitudesβ=0.21;perfectionismβ=0.25).Moreover,social support was found to moderate the mediating effect between NLEs,specific dysfunctional attitudes,and depressive symptoms(autonomy attitudes b2=-0.08;perfectionism b2=-0.09).CONCLUSION Dysfunctional attitudes mediated and social support moderated the relationship between NLEs and depression.Social support can buffer depression symptoms among adolescents with autonomy attitudes and perfectionism. 展开更多
关键词 DEPRESSION Dysfunctional attitudes social support Adolescents Moderated mediation model
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Comparative analyses of mitogenomes in the social bees with insights into evolution of long inverted repeats in the Meliponini 被引量:1
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作者 Yu-Ran Li Zheng-Wei Wang +1 位作者 Richard T.Corlett Wen-Bin Yu 《Zoological Research》 SCIE CSCD 2024年第1期160-175,共16页
The insect mitogenome is typically a compact circular molecule with highly conserved gene contents.Nonetheless,mitogenome structural variations have been reported in specific taxa,and gene rearrangements,usually the t... The insect mitogenome is typically a compact circular molecule with highly conserved gene contents.Nonetheless,mitogenome structural variations have been reported in specific taxa,and gene rearrangements,usually the tRNAs,occur in different lineages.Because synapomorphies of mitogenome organizations can provide information for phylogenetic inferences,comparative analyses of mitogenomes have been given increasing attention.However,most studies use a very few species to represent the whole genus,tribe,family,or even order,overlooking potential variations at lower taxonomic levels,which might lead to some incorrect inferences.To provide new insights into mitogenome organizations and their implications for phylogenetic inference,this study conducted comparative analyses for mitogenomes of three social bee tribes(Meliponini,Bombini,and Apini)based on the phylogenetic framework with denser taxonomic sampling at the species and population levels.Comparative analyses revealed that mitogenomes of Apini and Bombini are the typical type,while those of Meliponini show diverse variations in mitogenome sizes and organizations.Large inverted repeats(IRs)cause significant gene rearrangements of protein coding genes(PCGs)and rRNAs in Indo-Malay/Australian stingless bee species.Molecular evolution analyses showed that the lineage with IRs have lower dN/dS ratios for PCGs than lineages without IRs,indicating potential effects of IRs on the evolution of mitochondrial genes.The finding of IRs and different patterns of gene rearrangements suggested that Meliponini is a hotspot in mitogenome evolution.Unlike conserved PCGs and rRNAs whose rearrangements were found only in the mentioned lineages within Meliponini,tRNA rearrangements are common across all three tribes of social bees,and are significant even at the species level,indicating that comprehensive sampling is needed to fully understand the patterns of tRNA rearrangements,and their implications for phylogenetic inference. 展开更多
关键词 social bees PHYLOGENY Mitogenome structure Gene rearrangement Inverted repeats
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Adolescent suicide risk factors and the integration of socialemotional skills in school-based prevention programs 被引量:2
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作者 Xin-Qiao Liu Xin Wang 《World Journal of Psychiatry》 SCIE 2024年第4期494-506,共13页
Adolescents are considered one of the most vulnerable groups affected by suicide.Rapid changes in adolescents’physical and mental states,as well as in their lives,significantly and undeniably increase the risk of sui... Adolescents are considered one of the most vulnerable groups affected by suicide.Rapid changes in adolescents’physical and mental states,as well as in their lives,significantly and undeniably increase the risk of suicide.Psychological,social,family,individual,and environmental factors are important risk factors for suicidal behavior among teenagers and may contribute to suicide risk through various direct,indirect,or combined pathways.Social-emotional learning is considered a powerful intervention measure for addressing the crisis of adolescent suicide.When deliberately cultivated,fostered,and enhanced,selfawareness,self-management,social awareness,interpersonal skills,and responsible decision-making,as the five core competencies of social-emotional learning,can be used to effectively target various risk factors for adolescent suicide and provide necessary mental and interpersonal support.Among numerous suicide intervention methods,school-based interventions based on social-emotional competence have shown great potential in preventing and addressing suicide risk factors in adolescents.The characteristics of school-based interventions based on social-emotional competence,including their appropriateness,necessity,cost-effectiveness,comprehensiveness,and effectiveness,make these interventions an important means of addressing the crisis of adolescent suicide.To further determine the potential of school-based interventions based on social-emotional competence and better address the issue of adolescent suicide,additional financial support should be provided,the combination of socialemotional learning and other suicide prevention programs within schools should be fully leveraged,and cooperation between schools and families,society,and other environments should be maximized.These efforts should be considered future research directions. 展开更多
关键词 Adolescent suicide Risk factors social-emotional skills social and emotional learning SCHOOL Prevention
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Study on the Influence of Farmer Social Capital on Cooperative Supply Willingness of Agricultural Disaster Reduction Public Goods——Based on the Investigation on 515 Farmers
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作者 Jiarui XU Yi JIANG +1 位作者 Qi WO Shuying XIAO 《Asian Agricultural Research》 2017年第1期22-27,共6页
Based on social capital theory,related factors of three dimensions( structure dimension,cognition dimension and relation dimension) of farmer social capital are taken as independent variables,and famer's willingne... Based on social capital theory,related factors of three dimensions( structure dimension,cognition dimension and relation dimension) of farmer social capital are taken as independent variables,and famer's willingness to cooperatively supply agricultural disaster reduction public goods is taken as dependent variable. Taking 515 farmers in 27 villages of Hubei Province as investigation objects,the influence of farmer social capital on cooperative supply willingness of agricultural disaster reduction public goods is explored by Logistic regression model. Research results show that social solidarity,common value concept,social trust and reciprocal content have positive impact on farmer's willingness of cooperative supply,while annual household income,number of agricultural disaster reduction public goods and social network have negative impact on farmer's willingness of cooperative supply. 展开更多
关键词 social capital Agricultural disaster reduction public goods Cooperative supply Farmer’s willingness
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Investigation on children's social adaptive capacity
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作者 王亚萍 王宝燕 +3 位作者 陈蕴奇 王爱荣 张荣 牛小麟 《Journal of Medical Colleges of PLA(China)》 CAS 2002年第4期318-320,共3页
Objective: To understand the present conditions of Children's social adaptive capacity. Methods: Using the social viability measuring list on infants-junior middle school students revised by Zuo Qi-hua, the social... Objective: To understand the present conditions of Children's social adaptive capacity. Methods: Using the social viability measuring list on infants-junior middle school students revised by Zuo Qi-hua, the social viability and its influence factors were investigated on 628 Children in,7 kindergartens of 4 cities in Chi-na. Results: The general trend of development of Child''s social adaptive capacity was fairly good. The rele-vance ratio on the edge level was 0. 3%. Of them 16.4% and 7% were excellent and extraordinary intelli-gence respectively. The family environment had played a very important role in child''s social adaptive capaci-ty. Conclusion: The research revealed that in the respect of training a child''s social adaptive ability, the ini-tiative of each family should be brought into full play and we should surmount the negative influence, and solve the contradiction between releasing one''s control and taking care of everything, and arouse the con-scious activity of the child, and ensure the unity and balance between the child''s own body and the living en-vironment. 展开更多
关键词 CHILD social adaptive capacity Influence factors
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A Clinical Investigation: Study on Psychosocial Characteristics, Social Support and Intervention Strategies of Outpatient Cancer Pain Patients
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作者 Aijun Ji Ruchun Shi Chen Yu 《Journal of Cancer Therapy》 2023年第8期353-365,共16页
Background and Objective: The presence of pain in cancer patients is a prevalent concomitant symptom, exerting significant impacts on their physical, psychological, and social functioning. However, the psychological a... Background and Objective: The presence of pain in cancer patients is a prevalent concomitant symptom, exerting significant impacts on their physical, psychological, and social functioning. However, the psychological and social aspects are often overlooked. This study aims to explore the factors influencing the provision of psychological and social support for patients experiencing cancer-related pain while proposing intervention measures to enhance treatment compliance, confidence levels, and overall quality of life. Materials and Methods: According to the inclusion and exclusion criteria, a total of 108 patients with moderate to severe advanced cancer pain who had received outpatient analgesia treatment for at least one month were selected as the study subjects. The psychological characteristics and social support of these patients were further examined using the Self-Rating Symptom Scale (SCL-90) and Social Support Rating Scale (SSRS). The influencing factors were compared with the national norms. Results: The total score of SCL-90 was significantly different from that of the domestic norm (P < 0.05), and the total score of social support was significantly different from that of the domestic norm (P < 0.01). In addition to hostile symptoms, Somatic, obsessive, sensitive, depression, anxiety, terror, paranoia, psychosis and other symptoms were correlated with subjective support (P 0.05). Conclusion: Patients with cancer pain are more vulnerable to physical symptoms, psychological distress, lack of social support, and other contributing factors. Implementing standardized treatment protocols can effectively alleviate physical symptoms while also emphasizing the importance of psychosocial interventions to address negative emotions and enhance social support. By bolstering patient confidence through these measures, we can ultimately improve treatment outcomes and enhance patients’ overall quality of life. 展开更多
关键词 OUTPATIENT Cancer Pain PSYCHOsocial social Support
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Making the case for the evolving role of social media in health professions education and a literature review on the application of some in ophthalmology 被引量:1
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作者 Helena Prior Filipe Mila Kostic +1 位作者 Mildred Lopez Karl Golnik 《Annals of Eye Science》 2024年第2期1-11,共11页
Background and Objective:Social media(SoMe)has emerged as a tool in health professions education(HPE),particularly amidst the challenges posed by the coronavirus disease 2019(COVID-19)pandemic.Despite the academia’s ... Background and Objective:Social media(SoMe)has emerged as a tool in health professions education(HPE),particularly amidst the challenges posed by the coronavirus disease 2019(COVID-19)pandemic.Despite the academia’s initial skepticism SoMe has been gaining traction in supporting learning communities,and offering opportunities for innovation in HPE.Our study aims to explore the integration of SoMe in HPE.Four key components were outlined as necessary for a successful integration,and include designing learning experiences,defining educator roles,selecting appropriate platforms,and establishing educational objectives.Methods:This article stemmed from the online Teaching Skills Series module on SoMe in education from the Ophthalmology Foundation,and drew upon evidence supporting learning theories relevant to SoMe integration and models of education.Additionally,we conducted a literature review considering Englishlanguage articles on the application of SoMe in ophthalmology from PubMed over the past decade.Key Content and Findings:Early adopters of SoMe platforms in HPE have leveraged these tools to enhance learning experiences through interaction,dialogue,content sharing,and active learning strategies.By integrating SoMe into educational programs,both online and in-person,educators can overcome time and geographical constraints,fostering more diverse and inclusive learning communities.Careful consideration is,however,necessary to address potential limitations within HPE.Conclusions:This article lays groundwork for expanding SoMe integration in HPE design,emphasizing the supportive scaffold of various learning theories,and the need of furthering robust research on examining its advantages over traditional educational formats.Our literature review underscores an ongoing multifaceted,random application of SoMe platforms in ophthalmology education.We advocate for an effective incorporation of SoMe in HPE education,with the need to comply with good educational practice. 展开更多
关键词 social media(SoMe) health professions education(HPE) active learning social learning technology enhanced learning
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Spatiotemporal dynamics of the social structure of Indo-Pacific humpback dolphins(Sousa chinensis)in Xiamen waters from 2007 to 2019
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作者 Yi Lu Xin-Rong Xu +3 位作者 Bing-Yao Chen Thomas A Jefferson Holly Fearnbach Guang Yang 《Zoological Research》 SCIE CSCD 2024年第2期439-450,共12页
As highly social animals,Indo-Pacific humpback dolphins(Sousa chinensis)exhibit community differentiation.Nevertheless,our understanding of the external and internal factors influencing these dynamics,as well as their... As highly social animals,Indo-Pacific humpback dolphins(Sousa chinensis)exhibit community differentiation.Nevertheless,our understanding of the external and internal factors influencing these dynamics,as well as their spatiotemporal variations,is still limited.In the present study,variations in the social structure of an endangered Indo-Pacific humpback dolphin population in Xiamen Bay,China,were monitored over two distinct periods(2007–2010 and 2017–2019)to analyze the effects of habitat utilization and the composition of individuals within the population.In both periods,the population demonstrated a strikingly similar pattern of social differentiation,characterized by the division of individuals into two main clusters and one small cluster.Spatially,the two primary clusters occupied the eastern and western waters,respectively,although the core distribution area of the eastern cluster shifted further eastward between the two periods.Despite this distribution shift,the temporal stability of the social structure and inter-associations within the eastern cluster remained unaffected.A subset of 16individuals observed in both periods,comprising 51.6%and 43.2%of the population in each respective period,emerged as a foundational element of the social structure and may be responsible for sustaining social structure stability,especially during the 2007–2010 period.These observations suggest that the composition of dominant individuals,an internal factor,had a more substantial influence on the formation of the social network than changes in habitat use,an external factor.Consequently,the study proposes distinct conservation measures tailored to each of the two main clusters. 展开更多
关键词 social differentiation social structure Sousa chinensis DYNAMICS CONSERVATION
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Enhancing Data Forwarding Efficiency in SIoT with Multidimensional Social Relations
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作者 Fang Xu Songhao Jiang +3 位作者 Yi Ma Manzoor Ahmed Zenggang Xiong Yuanlin Lyu 《Computers, Materials & Continua》 SCIE EI 2024年第1期1095-1113,共19页
Effective data communication is a crucial aspect of the Social Internet of Things(SIoT)and continues to be a significant research focus.This paper proposes a data forwarding algorithm based on Multidimensional Social ... Effective data communication is a crucial aspect of the Social Internet of Things(SIoT)and continues to be a significant research focus.This paper proposes a data forwarding algorithm based on Multidimensional Social Relations(MSRR)in SIoT to solve this problem.The proposed algorithm separates message forwarding into intra-and cross-community forwarding by analyzing interest traits and social connections among nodes.Three new metrics are defined:the intensity of node social relationships,node activity,and community connectivity.Within the community,messages are sent by determining which node is most similar to the sender by weighing the strength of social connections and node activity.When a node performs cross-community forwarding,the message is forwarded to the most reasonable relay community by measuring the node activity and the connection between communities.The proposed algorithm was compared to three existing routing algorithms in simulation experiments.Results indicate that the proposed algorithmsubstantially improves message delivery efficiency while lessening network overhead and enhancing connectivity and coordination in the SIoT context. 展开更多
关键词 SIoT data forwarding social attributes social relations COMMUNITY
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基于Social Transformer的井下多人轨迹预测方法
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作者 马征 杨大山 张天翔 《工矿自动化》 CSCD 北大核心 2024年第5期67-74,共8页
目前煤矿井下人员轨迹预测方法中,Transformer与循环神经网络(RNN)、长短期记忆(LSTM)网络相比,在处理数据时不仅计算量小,同时还有效解决了梯度消失导致的长时依赖问题。但当环境中涉及多人同时运动时,Transformer对于场景中所有人员... 目前煤矿井下人员轨迹预测方法中,Transformer与循环神经网络(RNN)、长短期记忆(LSTM)网络相比,在处理数据时不仅计算量小,同时还有效解决了梯度消失导致的长时依赖问题。但当环境中涉及多人同时运动时,Transformer对于场景中所有人员未来轨迹的预测会出现较大偏差。并且目前在井下多人轨迹预测领域尚未出现一种同时采用Transformer并考虑个体之间相互影响的模型。针对上述问题,提出一种基于Social Transformer的井下多人轨迹预测方法。首先对井下每一个人员独立建模,获取人员历史轨迹信息,通过Transformer编码器进行特征提取,接着由全连接层对特征进行表示,然后通过基于图卷积的交互层相互连接,该交互层允许空间上接近的网络彼此共享信息,计算预测对象在受到周围邻居影响时对周围邻居分配的注意力,从而提取其邻居的运动模式,继而更新特征矩阵,最后新的特征矩阵由Transformer解码器进行解码,输出对于未来时刻的人员位置信息预测。实验结果表明,Social Transformer的平均位移误差相较于Transformer降低了45.8%,且与其他主流轨迹预测方法LSTM,S−GAN,Trajectron++和Social−STGCNN相比分别降低了67.1%,35.9%,30.1%和10.9%,有效克服了煤矿井下多人场景中由于人员间互相影响导致预测轨迹失准的问题,提升了预测精度。 展开更多
关键词 电子围栏 井下多人轨迹预测 TRANSFORMER 交互编码 social Transformer
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Numerical investigation of friction-heating-pressurization and its control parameters in the shear band of high-speed landslides
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作者 ZHAO Nenghao CUI Shenghua LU Haijun 《Journal of Mountain Science》 SCIE CSCD 2024年第10期3380-3395,共16页
High-speed sliding often leads to catastrophic landslides,many of which,in the initial sliding phase before disintegration,experience a friction-induced thermal pressurization effect in the bottom shear band,accelerat... High-speed sliding often leads to catastrophic landslides,many of which,in the initial sliding phase before disintegration,experience a friction-induced thermal pressurization effect in the bottom shear band,accelerating the movement of the overlying sliding mass.To quantitatively investigate this complex multiphysical phenomenon,we established a set of equations that describe the variations in temperature and excess pore pressure within the shear band,as well as the conservation of momentum equation for the overlying sliding mass.With a simplified landslide model,we investigated the variations of temperature and excess pore pressure within the shear band and their impacts on the velocity of the overlying sliding mass.On this basis,we studied the impact of seven key parameters on the maximum temperature and excess pore pressure in the shear band,as well as the impact on the velocity of the overlying sliding mass.The simulation results of the standard model show that the temperature and excess pore pressure in the shear band are significantly higher than those in the adjacent areas,and reach the maximum values in the center.Within a few seconds after the start,the maximum excess pore pressure in the shear zone is close to the initial stress,and the shear strength loss rate exceeds 90%.The thermal pressurization mechanism significantly increases the velocity of the overlying sliding mass.The results of parameter sensitivity analysis show that the thermal expansion coefficient has the most significant impact on the temperature and excess pore pressure in the shear band,and the sliding surface dip angle has the most significant impact on the velocity of the overlying sliding mass.The results of this study are of great significance for clarifying the mechanism of thermal pressurization-induced high-speed sliding. 展开更多
关键词 High-speed landslide Shear band Friction-heating-pressurization Numerical investigation
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Experimental investigation on the permeability of gap-graded soil due to horizontal suffusion considering boundary effect
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作者 Xuwei Wang Yeshuang Xu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第3期1072-1084,共13页
The boundary condition is a crucial factor affecting the permeability variation due to suffusion.An experimental investigation on the permeability of gap-graded soil due to horizontal suffusion considering the boundar... The boundary condition is a crucial factor affecting the permeability variation due to suffusion.An experimental investigation on the permeability of gap-graded soil due to horizontal suffusion considering the boundary effect is conducted,where the hydraulic head difference(DH)varies,and the boundary includes non-loss and soil-loss conditions.Soil samples are filled into seven soil storerooms connected in turn.After evaluation,the variation in content of fine sand(ΔR_(f))and the hydraulic conductivity of soils in each storeroom(C_(i))are analyzed.In the non-loss test,the soil sample filling area is divided into runoff,transited,and accumulated areas according to the negative or positive ΔR_(f) values.ΔR_(f) increases from negative to positive along the seepage path,and Ci decreases from runoff area to transited area and then rebounds in accumulated area.In the soil-loss test,all soil sample filling areas belong to the runoff area,where the gentle-loss,strengthened-loss,and alleviated-loss parts are further divided.ΔR_(f) decreases from the gentle-loss part to the strengthened-loss part and then rebounds in the alleviated-loss part,and C_(i) increases and then decreases along the seepage path.The relationship between ΔR_(f) and Ci is different with the boundary condition.Ci exponentially decreases with ΔR_(f) in the non-loss test and increases with ΔR_(f) generally in the soil-loss test. 展开更多
关键词 Suffusion PERMEABILITY Experimental investigation Boundary effect Horizontal seepage
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Privacy disclosure in Chinese social networking sites:An investigation of Renren users
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作者 Chenju ZHU Qi HUANG Qinghua ZHU 《Chinese Journal of Library and Information Science》 2014年第2期31-42,共12页
Purpose:This study was conducted to investigate the current situation of privacy disclosure(in the Chinese social networking sites.Design/methodology/approach:Data analysis was based on profiles of 240 college student... Purpose:This study was conducted to investigate the current situation of privacy disclosure(in the Chinese social networking sites.Design/methodology/approach:Data analysis was based on profiles of 240 college students on Renren.com,a popular college-oriented social networking site in China.Users’ privacy disclosure behaviors were studied and gender difference was analyzed particularly.Correlation analysis was conducted to examine the relationships among evaluation indicators involving user name,image,page visibility,message board visibility,completeness of education information and provision of personal information.Findings:A large amount of personal information was disclosed via social networking sites in China.Greater percentage of male users than female users disclosed their personal information.Furthermore,significantly positive relationships were found among page visibility,message board visibility,completeness of education information and provision of personal information.Research limitations:Subjects were collected from only one social networking website.Meanwhile,our survey involves subjective judgments of user name reliability,category of profile images and completeness of information.Practical implications:This study will be of benefit for college administrators,teachers and librarians to design courses for college students on how to use social networking sites safely.Originality /value:This empirical study is one of the first studies to reveal the current situation of privacy disclosure in the Chinese social networking sites and will help the research community gain a deeper understanding of privacy disclosure in the Chinese social networking sites. 展开更多
关键词 social networking site(SNS) Personal information Privacy disclosure Web 2.0
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Predicting Users’ Latent Suicidal Risk in Social Media: An Ensemble Model Based on Social Network Relationships
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作者 Xiuyang Meng Chunling Wang +3 位作者 Jingran Yang Mairui Li Yue Zhang Luo Wang 《Computers, Materials & Continua》 SCIE EI 2024年第6期4259-4281,共23页
Suicide has become a critical concern,necessitating the development of effective preventative strategies.Social media platforms offer a valuable resource for identifying signs of suicidal ideation.Despite progress in ... Suicide has become a critical concern,necessitating the development of effective preventative strategies.Social media platforms offer a valuable resource for identifying signs of suicidal ideation.Despite progress in detecting suicidal ideation on social media,accurately identifying individuals who express suicidal thoughts less openly or infrequently poses a significant challenge.To tackle this,we have developed a dataset focused on Chinese suicide narratives from Weibo’s Tree Hole feature and introduced an ensemble model named Text Convolutional Neural Network based on Social Network relationships(TCNN-SN).This model enhances predictive performance by leveraging social network relationship features and applying correction factors within a weighted linear fusion framework.It is specifically designed to identify key individuals who can help uncover hidden suicidal users and clusters.Our model,assessed using the bespoke dataset and benchmarked against alternative classification approaches,demonstrates superior accuracy,F1-score and AUC metrics,achieving 88.57%,88.75%and 94.25%,respectively,outperforming traditional TextCNN models by 12.18%,10.84%and 10.85%.We assert that our methodology offers a significant advancement in the predictive identification of individuals at risk,thereby contributing to the prevention and reduction of suicide incidences. 展开更多
关键词 Suicide risk prediction social media social network relationships Weibo Tree Hole deep learning
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