The effect of soya lecithin (SL) on solubilization and biodegradation of pentachlorophenol (PCP) by Anthracophyllum discolor was evaluated. Besides, the PCP effect on critical micelle concentration (CMC) of SL and the...The effect of soya lecithin (SL) on solubilization and biodegradation of pentachlorophenol (PCP) by Anthracophyllum discolor was evaluated. Besides, the PCP effect on critical micelle concentration (CMC) of SL and the effect of PCP and SL on the ligninolytic activity of A. discolor were evaluated. The PCP solubilization test was performed for 100, 200 and 400 mg·L-1 with SL solution varying concentrations of ranging from 0 to 0.9 g·L-1. The effect of PCP (5 to 20 mg·L-1) on CMC of SL by conductivity was evaluated. The effect of SL (0 to 0.9 g·L-1) on biodegradation of PCP (21.4 mg·L-1) in modified Kirk medium was studied. The results showed that SL addition enhanced PCP solubility in water. The solubilities of 100, 200 and 400 mg·L-1 of PCP were about 4.2, 5.0 and 2.5 times higher than their solubility in pure water when the system was added with 0.9 g·L-1 of SL. We found that the increase in PCP concentration caused a decrease in the CMC value. In the biodegradation assay, in liquid medium supplemented with 0.9 g·L-1 of SL, the 94.4% of PCP was biodegraded after 26 days of incubation. In contrast, in the control assay (without SL), the 76.5% of PCP was removed. The PCP degradation was confirmed by the presence of its metabolites. During biodegradation assay, A. discolor mainly produced manganese peroxidase reaching a maximum of 96.8 U·g-1 (dw) when the culture medium was added with 0.6 g·L-1 of SL. These results show that SL can be applied to increasing the bioavailability and biodegradation of PCP.展开更多
[Objectives]To probe into the treatment effects of soya lecithin powder combined with conventional therapy on chronic hepatitis B.[Methods]A total of 120 patients with chronic hepatitis B admitted to the Eighth People...[Objectives]To probe into the treatment effects of soya lecithin powder combined with conventional therapy on chronic hepatitis B.[Methods]A total of 120 patients with chronic hepatitis B admitted to the Eighth People’s Hospital of Guangzhou from February 2017 to February 2018 were randomly divided into observation group and control group in the way of drawing lots,with 60 cases in each group.Both groups of patients were treated with conventional therapy.On this basis,the control group was given Liver Protection Tablet,and the observation group was given soya lecithin powder for 2 months.The relief of symptoms of both groups and the recovery of liver functions were observed,including alanine aminotransferase(ALT),aspartate aminotransferase(AST),serum total bilirubin(TBIL),and glutamyl transpeptidase(GGT),as well as recovery of B-scan ultrasonography image and adverse drug reactions were observed.[Results]After treatment,the relief rate of fatigue,anorexia,abdominal distension and the disappearance rate of hepatic discomfort in the observation group were significant higher than those in the control group,and the difference was statistically significant(P<0.05);the recovery rate of ALT,AST,TBIL and GGT levels in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05);the recovery rate of B-scan ultrasonography image in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).No significant adverse drug reactions were found in two groups during the drug administration.[Conclusions]Soya lecithin powder combined with conventional therapy on chronic hepatitis B can significantly improve the liver function and relieve the symptoms.展开更多
文摘The effect of soya lecithin (SL) on solubilization and biodegradation of pentachlorophenol (PCP) by Anthracophyllum discolor was evaluated. Besides, the PCP effect on critical micelle concentration (CMC) of SL and the effect of PCP and SL on the ligninolytic activity of A. discolor were evaluated. The PCP solubilization test was performed for 100, 200 and 400 mg·L-1 with SL solution varying concentrations of ranging from 0 to 0.9 g·L-1. The effect of PCP (5 to 20 mg·L-1) on CMC of SL by conductivity was evaluated. The effect of SL (0 to 0.9 g·L-1) on biodegradation of PCP (21.4 mg·L-1) in modified Kirk medium was studied. The results showed that SL addition enhanced PCP solubility in water. The solubilities of 100, 200 and 400 mg·L-1 of PCP were about 4.2, 5.0 and 2.5 times higher than their solubility in pure water when the system was added with 0.9 g·L-1 of SL. We found that the increase in PCP concentration caused a decrease in the CMC value. In the biodegradation assay, in liquid medium supplemented with 0.9 g·L-1 of SL, the 94.4% of PCP was biodegraded after 26 days of incubation. In contrast, in the control assay (without SL), the 76.5% of PCP was removed. The PCP degradation was confirmed by the presence of its metabolites. During biodegradation assay, A. discolor mainly produced manganese peroxidase reaching a maximum of 96.8 U·g-1 (dw) when the culture medium was added with 0.6 g·L-1 of SL. These results show that SL can be applied to increasing the bioavailability and biodegradation of PCP.
文摘[Objectives]To probe into the treatment effects of soya lecithin powder combined with conventional therapy on chronic hepatitis B.[Methods]A total of 120 patients with chronic hepatitis B admitted to the Eighth People’s Hospital of Guangzhou from February 2017 to February 2018 were randomly divided into observation group and control group in the way of drawing lots,with 60 cases in each group.Both groups of patients were treated with conventional therapy.On this basis,the control group was given Liver Protection Tablet,and the observation group was given soya lecithin powder for 2 months.The relief of symptoms of both groups and the recovery of liver functions were observed,including alanine aminotransferase(ALT),aspartate aminotransferase(AST),serum total bilirubin(TBIL),and glutamyl transpeptidase(GGT),as well as recovery of B-scan ultrasonography image and adverse drug reactions were observed.[Results]After treatment,the relief rate of fatigue,anorexia,abdominal distension and the disappearance rate of hepatic discomfort in the observation group were significant higher than those in the control group,and the difference was statistically significant(P<0.05);the recovery rate of ALT,AST,TBIL and GGT levels in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05);the recovery rate of B-scan ultrasonography image in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).No significant adverse drug reactions were found in two groups during the drug administration.[Conclusions]Soya lecithin powder combined with conventional therapy on chronic hepatitis B can significantly improve the liver function and relieve the symptoms.
