This study aimed to evaluate the sensitivity and specificity of the new clinical diagnostic and classification criteria for Kashin-Beck disease （KBD） using six clinical markers： flexion of the distal part of finger...This study aimed to evaluate the sensitivity and specificity of the new clinical diagnostic and classification criteria for Kashin-Beck disease （KBD） using six clinical markers： flexion of the distal part of fingers, deformed fingers, enlarged finger joints, shortened fingers, squat down, and dwarfism. One-third of the total population in Linyou County was sampled by stratified random sampling.展开更多
It is unknown whether oxygen uptake(VO_(2))sampling intervals influence the efficacy of a verification stage following a graded exercise test(GXT).Fifteen females and 14 males(18-25 years)completed a maximal treadmill...It is unknown whether oxygen uptake(VO_(2))sampling intervals influence the efficacy of a verification stage following a graded exercise test(GXT).Fifteen females and 14 males(18-25 years)completed a maximal treadmill GXT.After a 5min recovery,the verification stage began at the speed and grade corresponding with the penultimate stage from the GXT.Maximal oxygen consumption(VO_(2max))from the incremental GXT(iVO_(2max))and VO_(2max)from the verification stage(verVO_(2max))were determined using 10 seconds(s),30s,and 60s from breath×breath averages.There was no main effect for VO_(2max)measure(iVO_(2max)vs.verVO_(2max))10s([47.9±8.31]ml∙kg^(−1)∙min^(−1)vs[48.85±7.97]ml∙kg^(−1)∙min^(−1)),30s([46.94±8.62]ml∙kg^(−1)∙min^(−1)vs[47.28±7.97]ml∙kg^(−1)∙min^(−1)),and 60s([46.17±8.62]ml∙kg^(−1)∙min^(−1)vs[46.00±8.00]ml∙kg^(−1)∙min^(−1)].There was a stage×sampling interval interaction as the difference between(verVO_(2max)−iVO_(2max))was greater for 10-s than 60-s sampling intervals.The verVO_(2max)was>4%higher than iVO_(2max)in 31%,31%,and 17%of the tests for the 10-s,30-s,and 60-s sampling intervals respectively.Sensitivity for the plateau was<30%for 10-s,30-s,and 60-s sampling intervals.Specificity ranged from 44%to 60%for all sampling intervals.Sensitivity for heart rate+respiratory exchange ratio was>90%for all sampling intervals;while specificity was<25%.Findings from the present study suggest that the efficacy of verification stages for eliciting a higher VO_(2max)may be influenced by the sampling interval utilized.展开更多
基金supported by the National Natural Scientific Foundation of China(81472924,81620108026)the Fundamental Research Funds for the Central Universities in 2015
文摘This study aimed to evaluate the sensitivity and specificity of the new clinical diagnostic and classification criteria for Kashin-Beck disease （KBD） using six clinical markers： flexion of the distal part of fingers, deformed fingers, enlarged finger joints, shortened fingers, squat down, and dwarfism. One-third of the total population in Linyou County was sampled by stratified random sampling.
文摘It is unknown whether oxygen uptake(VO_(2))sampling intervals influence the efficacy of a verification stage following a graded exercise test(GXT).Fifteen females and 14 males(18-25 years)completed a maximal treadmill GXT.After a 5min recovery,the verification stage began at the speed and grade corresponding with the penultimate stage from the GXT.Maximal oxygen consumption(VO_(2max))from the incremental GXT(iVO_(2max))and VO_(2max)from the verification stage(verVO_(2max))were determined using 10 seconds(s),30s,and 60s from breath×breath averages.There was no main effect for VO_(2max)measure(iVO_(2max)vs.verVO_(2max))10s([47.9±8.31]ml∙kg^(−1)∙min^(−1)vs[48.85±7.97]ml∙kg^(−1)∙min^(−1)),30s([46.94±8.62]ml∙kg^(−1)∙min^(−1)vs[47.28±7.97]ml∙kg^(−1)∙min^(−1)),and 60s([46.17±8.62]ml∙kg^(−1)∙min^(−1)vs[46.00±8.00]ml∙kg^(−1)∙min^(−1)].There was a stage×sampling interval interaction as the difference between(verVO_(2max)−iVO_(2max))was greater for 10-s than 60-s sampling intervals.The verVO_(2max)was>4%higher than iVO_(2max)in 31%,31%,and 17%of the tests for the 10-s,30-s,and 60-s sampling intervals respectively.Sensitivity for the plateau was<30%for 10-s,30-s,and 60-s sampling intervals.Specificity ranged from 44%to 60%for all sampling intervals.Sensitivity for heart rate+respiratory exchange ratio was>90%for all sampling intervals;while specificity was<25%.Findings from the present study suggest that the efficacy of verification stages for eliciting a higher VO_(2max)may be influenced by the sampling interval utilized.
