Non-invasive characterization of powders may take one of two approaches:imaging and counting individual particles;or relying on scattered light to estimate the particle size distribution(PSD)of the ensemble.The former...Non-invasive characterization of powders may take one of two approaches:imaging and counting individual particles;or relying on scattered light to estimate the particle size distribution(PSD)of the ensemble.The former approach runs into practical difficulties,as the system must conform to the working distance and other restrictions of the imaging optics.The latter approach requires an inverse map from the speckle autocorrelation to the particle sizes.The principle relies on the pupil function determining the basic sidelobe shape,whereas the particle size spread modulates the sidelobe intensity.We recently showed that it is feasible to invert the speckle autocorrelation and obtain the PSD using a neural network,trained efficiently through a physics-informed semi-generative approach.In this work,we eliminate one of the most time-consuming steps of our previous method by engineering the pupil function.By judiciously blocking portions of the pupil,we sacrifice some photons but in return we achieve much enhanced sidelobes and,hence,higher sensitivity to the change of the size distribution.The result is a 60×reduction in total acquisition and processing time,or 0.25 seconds per frame in our implementation.Almost real-time operation in our system is not only more appealing toward rapid industrial adoption,it also paves the way for quantitative characterization of complex spatial or temporal dynamics in drying,blending,and other chemical and pharmaceutical manufacturing processes.展开更多
Temporary spinal cord stimulation(tSCS)can effectively reduce the pain and severity of postherpetic neuralgia(PHN).However,there are no effective and objective methods for predicting the effects of tSCS on PHN.Laser s...Temporary spinal cord stimulation(tSCS)can effectively reduce the pain and severity of postherpetic neuralgia(PHN).However,there are no effective and objective methods for predicting the effects of tSCS on PHN.Laser speckle contrast imaging(LSCI)is frequently used in neurology to evaluate the effectiveness of treatment.To assess the accuracy of LSCI in predicting the impact of tSCS on PHN,14 adult patients receiving tSCS treatments for spinal nerve-innervated(C6-T2)PHN participated in this observational study.Visual analog scale(VAS)assessments and LSCI bloodflow images of the-ngers were recorded after the tSCS procedure.The results showed that the VAS scores of all patients decreased signi-cantly.Moreover,the bloodflow index(BFI)values were signi-cantly higher than they were before the procedure.Increased bloodflow and pain alleviation were positively correlated.The-ndings indicated that spinal nerve PHN(C6-T2)was signi-cantly reduced by tSCS.Pain alleviation by tSCS was positively correlated with increased bloodflow in the hand.The effect of tSCS on PHN may thus be predicted using an independent and consistent indicator such as LSCI.展开更多
BACKGROUND Diabetic cardiomyopathy is considered as a chronic complication of diabetes mellitus(DM).Therefore,early detection of left ventricular systolic function(LVSF)damage in DM is essential.AIM To explore the use...BACKGROUND Diabetic cardiomyopathy is considered as a chronic complication of diabetes mellitus(DM).Therefore,early detection of left ventricular systolic function(LVSF)damage in DM is essential.AIM To explore the use of the three-dimensional speckle tracking technique(3D-STI)for measuring LVSF in DM patients via meta-analysis.METHODS The electronic databases were retrieved from the initial accessible time to 29 April 2023.The current study involved 9 studies,including 970 subjects.We carried out this meta-analysis to estimate myocardial function in DM compared with controls according to myocardial strain attained by 3D-STI.RESULTS Night articles including 970 subjects were included.No significant difference was detected in the left ventricular ejection fraction between the control and the diabetic group(P>0.05),while differences in global longitudinal strain,global circumferential strain,global radial strain,and global area strain were markedly different between the controls and DM patients(all P<0.05).CONCLUSION The 3D-STI could be applied to accurately measure early LVSF damage in patients with DM.展开更多
Structured illumination microscopy(SIM)is one of the most widely applied wide field super resolution imaging techniques with high temporal resolution and low phototoxicity.The spatial resolution of SIM is typically li...Structured illumination microscopy(SIM)is one of the most widely applied wide field super resolution imaging techniques with high temporal resolution and low phototoxicity.The spatial resolution of SIM is typically limited to two times of the diffraction limit and the depth of field is small.In this work,we propose and experimentally demonstrate a low cost,easy to implement,novel technique called speckle structured illumination endoscopy(SSIE)to enhance the resolution of a wide field endoscope with large depth of field.Here,speckle patterns are used to excite objects on the sample which is then followed by a blind-SIM algorithm for super resolution image reconstruction.Our approach is insensitive to the 3D morphology of the specimen,or the deformation of illuminations used.It greatly simplifies the experimental setup as there are no calibration protocols and no stringent control of illumination patterns nor focusing optics.We demonstrate that the SSIE can enhance the resolution 2–4.5 times that of a standard white light endoscopic(WLE)system.The SSIE presents a unique route to super resolution in endoscopic imaging at wide field of view and depth of field,which might be beneficial to the practice of clinical endoscopy.展开更多
Significant progress has been made in computational imaging(CI),in which deep convolutional neural networks(CNNs)have demonstrated that sparse speckle patterns can be reconstructed.However,due to the limited“local”k...Significant progress has been made in computational imaging(CI),in which deep convolutional neural networks(CNNs)have demonstrated that sparse speckle patterns can be reconstructed.However,due to the limited“local”kernel size of the convolutional operator,for the spatially dense patterns,such as the generic face images,the performance of CNNs is limited.Here,we propose a“non-local”model,termed the Speckle-Transformer(SpT)UNet,for speckle feature extraction of generic face images.It is worth noting that the lightweight SpT UNet reveals a high efficiency and strong comparative performance with Pearson Correlation Coefficient(PCC),and structural similarity measure(SSIM)exceeding 0.989,and 0.950,respectively.展开更多
Laser speckle contrast imaging(LSCI)is a powerful tool for monitoring blood flow changes in tissue or vessels in vivo,but its applications are limited by shallow penetration depth under reflective imaging configuratio...Laser speckle contrast imaging(LSCI)is a powerful tool for monitoring blood flow changes in tissue or vessels in vivo,but its applications are limited by shallow penetration depth under reflective imaging configuration.The traditional LSCI setup has been used in transmissive imaging for depth extension up to 2l_(t)–3l_(t)(l_(t)is the transport mean free path),but the blood flow estimation is biased due to the depth uncertainty in large depth of field(DOF)images.In this study,we propose a transmissive multifocal LSCI for depth-resolved blood flow in thick tissue,further extending the transmissive LSCI for tissue thickness up to 12lt.The limited-DOF imaging system is applied to the multifocal acquisition,and the depth of the vessel is estimated using a robust visibility parameter V_(r)in the coherent domain.The accuracy and linearity of depth estimation are tested by Monte Carlo simulations.Based on the proposed method,the model of contrast analysis resolving the depth information is established and verified in a phantom experiment.We demonstrated its effectiveness in acquiring depth-resolved vessel structures and flow dynamics in in vivo imaging of chick embryos.展开更多
The internal energy distribution of waves can be described using ocean-wave spectra.In many ways,obtaining wave spectra on a global scale is critical.Surface waves investigation and monitoring onboard the Chinese-Fren...The internal energy distribution of waves can be described using ocean-wave spectra.In many ways,obtaining wave spectra on a global scale is critical.Surface waves investigation and monitoring onboard the Chinese-French oceanography satellite is the first space-borne instrument for detecting wave spectra specially,which was launched on October 29,2018.It can avoid the shortage of synthetic aperture radar detection results while still having some problems,especially with the effects of speckle noise.In this study,a method to suppress the speckle noise is proposed.First,the empirical formula for background speckle noise is established.Second,many spatio-temporal representative fluctuation spectra are classified and averaged.Third,rational transfer function filtering is used to obtain speckle noise close to the along-track direction.Finally,a signal-to-noise ratio threshold is used to suppress the abnormal speckle noise.This method solves the problems existing in previous denoising methods,such as excessive denoising in the along-track direction and the inability of some abnormal noises to be denoised in the two-dimensional directional wave spectra.展开更多
A new mechanism for the generation of high intensity speckles by coupling of overlapping beams is discovered and studied in detail.Using three-dimensional simulations,the coupling of overlapping beams smoothed by phas...A new mechanism for the generation of high intensity speckles by coupling of overlapping beams is discovered and studied in detail.Using three-dimensional simulations,the coupling of overlapping beams smoothed by phase plates and by polarization smoothing are investigated in the regime relevant to inertial confinement fusion studies.It is found that the intensity distribution of the laser beam spot can be changed by nonuniform spatial phase modulation,and the speckles formed by the phase plate can be split into smaller speckles with higher intensities,which is favorable for the generation of laser plasma instabilities.Stimulated Brillouin scattering is compared in simulations with and without coupling of the overlapping incident beams,and the results confirm the enhancement of stimulated Brillouin scattering due to this mechanism.展开更多
In spite of the advancement in computerized imaging,many image modalities produce images with commotion influencing both the visual quality and upsetting quantitative image analysis.In this way,the research in the zone...In spite of the advancement in computerized imaging,many image modalities produce images with commotion influencing both the visual quality and upsetting quantitative image analysis.In this way,the research in the zone of image denoising is very dynamic.Among an extraordinary assortment of image restoration and denoising techniques the neural network system-based noise sup-pression is a basic and productive methodology.In this paper,Bilateral Filter(BF)based Modular Neural Networks(MNN)has been utilized for speckle noise sup-pression in the ultrasound image.Initial step the BFfilter is used tofilter the input image.From the output of BF,statistical features such as mean,standard devia-tion,median and kurtosis have been extracted and these features are used to train the MNN.Then,thefiltered images from the BF are again denoised using MNN.The ultrasound dataset from the Kaggle site is used for the training and testing process.The simulation outcomes demonstrate that the BF-MNNfiltering method performs better for the multiplicative noise concealment in UltraSound(US)images.From the simulation results,it has been observed that BF-MNN performs better than the existing techniques in terms of peak signal to noise ratio(34.89),Structural Similarity Index(0.89)and Edge Preservation Index(0.67).展开更多
In order to get an effective solution of the in-flight wing deformation measurement for high-wing aircrafts with high-aspect-ratio,a method based on three-dimensional(3D)speckle correlation technique is proposed.First...In order to get an effective solution of the in-flight wing deformation measurement for high-wing aircrafts with high-aspect-ratio,a method based on three-dimensional(3D)speckle correlation technique is proposed.Firstly,an in-flight wing deformation measurement system with two sets of conjugate cameras is designed based on structural characteristics and test requirements of high-wing aircrafts with large-aspect-ratio.Secondly,the in-flight wing deformation measurement method based on 3D speckle correlation technique is introduced including three aspects:measuring system and wing datum calibration,speckle image matching and 3D reconstruction,and wing deformation analysis.Fi-nally,ground simulation test of dynamic deformation measurement of a scaled model wing and flight test of dynamic deformation measurement of a large transport wing are carried out.The test results show that the measuring accuracy of single point coordinate in ground simulation test is better than 0.1 mm/m,in the airborne vibration environment,the static single-point positioning accuracy is bet-ter than 5 mm,and the in-flight wing deformation measurement data is well received by the flight test engineers.This method can satisfy the requirements of stability,reliability,high precision,non-con-tact and full-field measurement for dynamic deformation measurement of aircraft wing with high-as-pect-ratio.展开更多
This paper discusses and studies the composition and characteristics of biospeckle on the surface of bone tissues.We used a laser speckle device to capture biospeckle patterns from fresh pig bone tissue.Traditional sp...This paper discusses and studies the composition and characteristics of biospeckle on the surface of bone tissues.We used a laser speckle device to capture biospeckle patterns from fresh pig bone tissue.Traditional speckle activity metrics were used to measure the speckle activity of ex vivo bone tissue over time.Both Gaussian and Lorentzian correlation functions were used to char-acterize the ordered and disordered motion of the bone surface,together with volume scattering,to construct the model.Using the established mathematical model of the spatio-temporal evo-lution of the biospeckle pattern,it is possible to account for the presence of volume scattering from the biospeckle of bones,quantify the ordered or disordered motions in the biological speckle activity at the current time,and assess the ability of laser speckle correlation technique to determine biological activity.展开更多
When a surface is illuminated by laser,the field of diffusing reflective light can be described by Fresnel-Kirchhoff integration in the region of Fresnel.If the correlation,before and after the change of intensity fie...When a surface is illuminated by laser,the field of diffusing reflective light can be described by Fresnel-Kirchhoff integration in the region of Fresnel.If the correlation,before and after the change of intensity field,is analysed by statistical method,three governing equations for variations of intensity field and speckle movement formulas can be obtained.In these equations,the surface motion,deformation and wavelength change are all considered to cause the speckle movement.展开更多
The influence of ischemia-reperfusion(I/R)action on pancreatic blood flow(PBF)and the development of acute pancreatitis(AP)in laboratory rats is evaluated in vivo by using the laser speckle contrast imaging(LSCI).Addi...The influence of ischemia-reperfusion(I/R)action on pancreatic blood flow(PBF)and the development of acute pancreatitis(AP)in laboratory rats is evaluated in vivo by using the laser speckle contrast imaging(LSCI).Additionally,the optical properties in norm and under condition of AP in rats were assessed using a modied integrating sphere spectrometer and inverse Monte Carlo(IMC)software.The results of the experimental study of microcirculation of the pancreas in 82 rats in the ischemic model are presented.The data obtained conrm the fact that local ischemia and changes in the blood°ow velocity of the main vessels cause and provoke acute pancreatitis.展开更多
The quality of ultrasound scanning images is usually damaged by speckle noise.This paper proposes a method based on local statistics extracted from a histogram to reduce ultrasound speckle through a region growing alg...The quality of ultrasound scanning images is usually damaged by speckle noise.This paper proposes a method based on local statistics extracted from a histogram to reduce ultrasound speckle through a region growing algorithm.Unlike single statistical moment-based speckle reduction algorithms,this method adaptively smooths the speckle regions while preserving the margin and tissue structure to achieve high detectability.The criterion of a speckle region is defined by the similarity value obtained by matching the histogram of the current processing window and the reference window derived from the speckle region in advance.Then,according to the similarity value and tissue characteristics,the entire image is divided into several levels of speckle-content regions,and adaptive smoothing is performed based on these classification characteristics and the corresponding window size determined by the proposed region growing technique.Tests conducted from phantoms and in vivo images have shown very promising results after a quantitative and qualitative comparison with existing work.展开更多
基金the following funding support:Millennium Pharmaceuticals,Inc.(a subsidiary of Takeda Pharmaceuticals)D824-MT15National Research Foundation,Singapore,Intra-Create thematic grant NRF2019-THE002-0006.
文摘Non-invasive characterization of powders may take one of two approaches:imaging and counting individual particles;or relying on scattered light to estimate the particle size distribution(PSD)of the ensemble.The former approach runs into practical difficulties,as the system must conform to the working distance and other restrictions of the imaging optics.The latter approach requires an inverse map from the speckle autocorrelation to the particle sizes.The principle relies on the pupil function determining the basic sidelobe shape,whereas the particle size spread modulates the sidelobe intensity.We recently showed that it is feasible to invert the speckle autocorrelation and obtain the PSD using a neural network,trained efficiently through a physics-informed semi-generative approach.In this work,we eliminate one of the most time-consuming steps of our previous method by engineering the pupil function.By judiciously blocking portions of the pupil,we sacrifice some photons but in return we achieve much enhanced sidelobes and,hence,higher sensitivity to the change of the size distribution.The result is a 60×reduction in total acquisition and processing time,or 0.25 seconds per frame in our implementation.Almost real-time operation in our system is not only more appealing toward rapid industrial adoption,it also paves the way for quantitative characterization of complex spatial or temporal dynamics in drying,blending,and other chemical and pharmaceutical manufacturing processes.
基金supported by the Clinical Frontier Technology Program of the First A±liated Hospital of Jinan University,China(No.JNU1AFCFTP-2022-a01212)the Clinical Research Funds for the First Clinical Medicine College of Jinan University(Grant No.2018006).
文摘Temporary spinal cord stimulation(tSCS)can effectively reduce the pain and severity of postherpetic neuralgia(PHN).However,there are no effective and objective methods for predicting the effects of tSCS on PHN.Laser speckle contrast imaging(LSCI)is frequently used in neurology to evaluate the effectiveness of treatment.To assess the accuracy of LSCI in predicting the impact of tSCS on PHN,14 adult patients receiving tSCS treatments for spinal nerve-innervated(C6-T2)PHN participated in this observational study.Visual analog scale(VAS)assessments and LSCI bloodflow images of the-ngers were recorded after the tSCS procedure.The results showed that the VAS scores of all patients decreased signi-cantly.Moreover,the bloodflow index(BFI)values were signi-cantly higher than they were before the procedure.Increased bloodflow and pain alleviation were positively correlated.The-ndings indicated that spinal nerve PHN(C6-T2)was signi-cantly reduced by tSCS.Pain alleviation by tSCS was positively correlated with increased bloodflow in the hand.The effect of tSCS on PHN may thus be predicted using an independent and consistent indicator such as LSCI.
文摘BACKGROUND Diabetic cardiomyopathy is considered as a chronic complication of diabetes mellitus(DM).Therefore,early detection of left ventricular systolic function(LVSF)damage in DM is essential.AIM To explore the use of the three-dimensional speckle tracking technique(3D-STI)for measuring LVSF in DM patients via meta-analysis.METHODS The electronic databases were retrieved from the initial accessible time to 29 April 2023.The current study involved 9 studies,including 970 subjects.We carried out this meta-analysis to estimate myocardial function in DM compared with controls according to myocardial strain attained by 3D-STI.RESULTS Night articles including 970 subjects were included.No significant difference was detected in the left ventricular ejection fraction between the control and the diabetic group(P>0.05),while differences in global longitudinal strain,global circumferential strain,global radial strain,and global area strain were markedly different between the controls and DM patients(all P<0.05).CONCLUSION The 3D-STI could be applied to accurately measure early LVSF damage in patients with DM.
基金partially supported by the Gordon and Betty Moore Foundation Grant No.5722
文摘Structured illumination microscopy(SIM)is one of the most widely applied wide field super resolution imaging techniques with high temporal resolution and low phototoxicity.The spatial resolution of SIM is typically limited to two times of the diffraction limit and the depth of field is small.In this work,we propose and experimentally demonstrate a low cost,easy to implement,novel technique called speckle structured illumination endoscopy(SSIE)to enhance the resolution of a wide field endoscope with large depth of field.Here,speckle patterns are used to excite objects on the sample which is then followed by a blind-SIM algorithm for super resolution image reconstruction.Our approach is insensitive to the 3D morphology of the specimen,or the deformation of illuminations used.It greatly simplifies the experimental setup as there are no calibration protocols and no stringent control of illumination patterns nor focusing optics.We demonstrate that the SSIE can enhance the resolution 2–4.5 times that of a standard white light endoscopic(WLE)system.The SSIE presents a unique route to super resolution in endoscopic imaging at wide field of view and depth of field,which might be beneficial to the practice of clinical endoscopy.
基金funding support from the Science and Technology Commission of Shanghai Municipality(Grant No.21DZ1100500)the Shanghai Frontiers Science Center Program(2021-2025 No.20)+2 种基金the Zhangjiang National Innovation Demonstration Zone(Grant No.ZJ2019ZD-005)supported by a fellowship from the China Postdoctoral Science Foundation(2020M671169)the International Postdoctoral Exchange Program from the Administrative Committee of Post-Doctoral Researchers of China([2020]33)。
文摘Significant progress has been made in computational imaging(CI),in which deep convolutional neural networks(CNNs)have demonstrated that sparse speckle patterns can be reconstructed.However,due to the limited“local”kernel size of the convolutional operator,for the spatially dense patterns,such as the generic face images,the performance of CNNs is limited.Here,we propose a“non-local”model,termed the Speckle-Transformer(SpT)UNet,for speckle feature extraction of generic face images.It is worth noting that the lightweight SpT UNet reveals a high efficiency and strong comparative performance with Pearson Correlation Coefficient(PCC),and structural similarity measure(SSIM)exceeding 0.989,and 0.950,respectively.
基金supported by National Natural Science Foundation of China(NSFC No.61876108)the National Key Research&Development Program of Ministry of Science and Technology of the People's Republic of China(Grant Nos.2018YFC2002300,2018YFC2002303).
文摘Laser speckle contrast imaging(LSCI)is a powerful tool for monitoring blood flow changes in tissue or vessels in vivo,but its applications are limited by shallow penetration depth under reflective imaging configuration.The traditional LSCI setup has been used in transmissive imaging for depth extension up to 2l_(t)–3l_(t)(l_(t)is the transport mean free path),but the blood flow estimation is biased due to the depth uncertainty in large depth of field(DOF)images.In this study,we propose a transmissive multifocal LSCI for depth-resolved blood flow in thick tissue,further extending the transmissive LSCI for tissue thickness up to 12lt.The limited-DOF imaging system is applied to the multifocal acquisition,and the depth of the vessel is estimated using a robust visibility parameter V_(r)in the coherent domain.The accuracy and linearity of depth estimation are tested by Monte Carlo simulations.Based on the proposed method,the model of contrast analysis resolving the depth information is established and verified in a phantom experiment.We demonstrated its effectiveness in acquiring depth-resolved vessel structures and flow dynamics in in vivo imaging of chick embryos.
文摘The internal energy distribution of waves can be described using ocean-wave spectra.In many ways,obtaining wave spectra on a global scale is critical.Surface waves investigation and monitoring onboard the Chinese-French oceanography satellite is the first space-borne instrument for detecting wave spectra specially,which was launched on October 29,2018.It can avoid the shortage of synthetic aperture radar detection results while still having some problems,especially with the effects of speckle noise.In this study,a method to suppress the speckle noise is proposed.First,the empirical formula for background speckle noise is established.Second,many spatio-temporal representative fluctuation spectra are classified and averaged.Third,rational transfer function filtering is used to obtain speckle noise close to the along-track direction.Finally,a signal-to-noise ratio threshold is used to suppress the abnormal speckle noise.This method solves the problems existing in previous denoising methods,such as excessive denoising in the along-track direction and the inability of some abnormal noises to be denoised in the two-dimensional directional wave spectra.
基金supported by the National Natural Sci-ence Foundation of China(Grant Nos.12275032,12035002,and 12205021)the Project supported by CAEP Foundation(Grant No.CX20210040).
文摘A new mechanism for the generation of high intensity speckles by coupling of overlapping beams is discovered and studied in detail.Using three-dimensional simulations,the coupling of overlapping beams smoothed by phase plates and by polarization smoothing are investigated in the regime relevant to inertial confinement fusion studies.It is found that the intensity distribution of the laser beam spot can be changed by nonuniform spatial phase modulation,and the speckles formed by the phase plate can be split into smaller speckles with higher intensities,which is favorable for the generation of laser plasma instabilities.Stimulated Brillouin scattering is compared in simulations with and without coupling of the overlapping incident beams,and the results confirm the enhancement of stimulated Brillouin scattering due to this mechanism.
文摘In spite of the advancement in computerized imaging,many image modalities produce images with commotion influencing both the visual quality and upsetting quantitative image analysis.In this way,the research in the zone of image denoising is very dynamic.Among an extraordinary assortment of image restoration and denoising techniques the neural network system-based noise sup-pression is a basic and productive methodology.In this paper,Bilateral Filter(BF)based Modular Neural Networks(MNN)has been utilized for speckle noise sup-pression in the ultrasound image.Initial step the BFfilter is used tofilter the input image.From the output of BF,statistical features such as mean,standard devia-tion,median and kurtosis have been extracted and these features are used to train the MNN.Then,thefiltered images from the BF are again denoised using MNN.The ultrasound dataset from the Kaggle site is used for the training and testing process.The simulation outcomes demonstrate that the BF-MNNfiltering method performs better for the multiplicative noise concealment in UltraSound(US)images.From the simulation results,it has been observed that BF-MNN performs better than the existing techniques in terms of peak signal to noise ratio(34.89),Structural Similarity Index(0.89)and Edge Preservation Index(0.67).
基金Supported by the National Natural Science Foundation of China(No.62271400).
文摘In order to get an effective solution of the in-flight wing deformation measurement for high-wing aircrafts with high-aspect-ratio,a method based on three-dimensional(3D)speckle correlation technique is proposed.Firstly,an in-flight wing deformation measurement system with two sets of conjugate cameras is designed based on structural characteristics and test requirements of high-wing aircrafts with large-aspect-ratio.Secondly,the in-flight wing deformation measurement method based on 3D speckle correlation technique is introduced including three aspects:measuring system and wing datum calibration,speckle image matching and 3D reconstruction,and wing deformation analysis.Fi-nally,ground simulation test of dynamic deformation measurement of a scaled model wing and flight test of dynamic deformation measurement of a large transport wing are carried out.The test results show that the measuring accuracy of single point coordinate in ground simulation test is better than 0.1 mm/m,in the airborne vibration environment,the static single-point positioning accuracy is bet-ter than 5 mm,and the in-flight wing deformation measurement data is well received by the flight test engineers.This method can satisfy the requirements of stability,reliability,high precision,non-con-tact and full-field measurement for dynamic deformation measurement of aircraft wing with high-as-pect-ratio.
基金This research is supported by the National Natural Science Foundation of China(51975116)Natural Science Foundation of Shanghai(21ZR1402900)the Fundamental Research Funds for the Central Universities and Graduate Student Innovation Fund of Donghua University(CUSF-DH-D-2021057).
文摘This paper discusses and studies the composition and characteristics of biospeckle on the surface of bone tissues.We used a laser speckle device to capture biospeckle patterns from fresh pig bone tissue.Traditional speckle activity metrics were used to measure the speckle activity of ex vivo bone tissue over time.Both Gaussian and Lorentzian correlation functions were used to char-acterize the ordered and disordered motion of the bone surface,together with volume scattering,to construct the model.Using the established mathematical model of the spatio-temporal evo-lution of the biospeckle pattern,it is possible to account for the presence of volume scattering from the biospeckle of bones,quantify the ordered or disordered motions in the biological speckle activity at the current time,and assess the ability of laser speckle correlation technique to determine biological activity.
基金The project supported by National Natural Science Foundation of China
文摘When a surface is illuminated by laser,the field of diffusing reflective light can be described by Fresnel-Kirchhoff integration in the region of Fresnel.If the correlation,before and after the change of intensity field,is analysed by statistical method,three governing equations for variations of intensity field and speckle movement formulas can be obtained.In these equations,the surface motion,deformation and wavelength change are all considered to cause the speckle movement.
基金the nancial sup-port of the Project No.13.2251.21.0009 of the Ministry of Science and Higher Education of the Russian Federation.
文摘The influence of ischemia-reperfusion(I/R)action on pancreatic blood flow(PBF)and the development of acute pancreatitis(AP)in laboratory rats is evaluated in vivo by using the laser speckle contrast imaging(LSCI).Additionally,the optical properties in norm and under condition of AP in rats were assessed using a modied integrating sphere spectrometer and inverse Monte Carlo(IMC)software.The results of the experimental study of microcirculation of the pancreas in 82 rats in the ischemic model are presented.The data obtained conrm the fact that local ischemia and changes in the blood°ow velocity of the main vessels cause and provoke acute pancreatitis.
基金This study is supported by the Chunhui Project(No.Z2015108)the Ministry of Education China,the Sichuan Science and Technology Program(No.2019YFG0196)+2 种基金the high-level personnel launch scientific research projects of Guizhou Institute of Technology(No.XJGC 20150105)the Science&Technology Department of Guizhou Province and Guizhou Institute of Technology Collaborative Fund LH(No.[2015]7104)the invitation for bid Project of Education Department of Guizhou Province KY(No.[2015]360).
文摘The quality of ultrasound scanning images is usually damaged by speckle noise.This paper proposes a method based on local statistics extracted from a histogram to reduce ultrasound speckle through a region growing algorithm.Unlike single statistical moment-based speckle reduction algorithms,this method adaptively smooths the speckle regions while preserving the margin and tissue structure to achieve high detectability.The criterion of a speckle region is defined by the similarity value obtained by matching the histogram of the current processing window and the reference window derived from the speckle region in advance.Then,according to the similarity value and tissue characteristics,the entire image is divided into several levels of speckle-content regions,and adaptive smoothing is performed based on these classification characteristics and the corresponding window size determined by the proposed region growing technique.Tests conducted from phantoms and in vivo images have shown very promising results after a quantitative and qualitative comparison with existing work.