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SPIN1通过调控上皮-间质转化促进胃癌细胞的迁移、浸润 被引量:2
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作者 吕蓓蓓 刘海亭 +3 位作者 陈旭 王亚文 宋琳 高鹏 《临床与实验病理学杂志》 CAS CSCD 北大核心 2021年第3期341-344,共4页
目的明确SPIN1在胃癌细胞系中的表达情况及其对胃癌细胞迁移、浸润的作用,初步探究其可能的分子机制。方法qRT-PCR检测SPIN1在5种胃癌细胞系中的表达情况;Transwell小室实验观察过表达及沉默SPIN1后细胞迁移和侵袭能力的变化;Western b... 目的明确SPIN1在胃癌细胞系中的表达情况及其对胃癌细胞迁移、浸润的作用,初步探究其可能的分子机制。方法qRT-PCR检测SPIN1在5种胃癌细胞系中的表达情况;Transwell小室实验观察过表达及沉默SPIN1后细胞迁移和侵袭能力的变化;Western blot法检测过表达及沉默SPIN1后上皮-间质转化(epithelial-mesenchymal transition,EMT)相关蛋白的表达变化。结果SPIN1在转移性胃癌细胞系SGC7901中表达量最高,过表达SPIN1可以促进胃癌细胞的迁移及浸润能力,沉默SPIN1可以抑制胃癌细胞的迁移及浸润能力。过表达/沉默SPIN1后可以导致Slug表达上调/下调及Claudin-1表达下调/上调。结论SPIN1与胃癌的浸润、转移密切相关,SPIN1通过正向调控Slug导致Claudin-1表达下调进而促进EMT进程,从而促进胃癌细胞的迁移、浸润。 展开更多
关键词 胃肿瘤 迁移 浸润 spin1 上皮-间质转化
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Key Problems of Cold Power Spinning of Ti-15-3 Alloy 被引量:1
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作者 Debin SHAN Yan LU and Ping LI School of Materials Science and Engineering, Harbin institute of Thchnology, Harbin 150001, China Yi XU Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110015, China 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2001年第1期125-126,共2页
The key problems of cold power spinning of Ti-15-3 alloy are studied. Reasonable billet preparation methods are presented to improve crystal structure and avoid crack of billet. Influences of original wall thickness,... The key problems of cold power spinning of Ti-15-3 alloy are studied. Reasonable billet preparation methods are presented to improve crystal structure and avoid crack of billet. Influences of original wall thickness, reduction rate and feed rate on expanding in diameter are analyzed and some methods to prevent expanding in diameter are given. 展开更多
关键词 TI Key Problems of Cold Power spinning of Ti-15-3 Alloy
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Research on A Master - slave Multi - microcomputers Control System for Hollow Spindle Fancy Yarn Spinning Machine
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作者 李志蜂 陈子展 阵瑞琪 《Journal of China Textile University(English Edition)》 EI CAS 1999年第1期49-52,共4页
In this paper, a successfully studied and developed master - slave muld - microcomputers control system based on PC - BUS for hollow spindle fancy yarn spinning machine, mainly Its overall scheme, software and hardwar... In this paper, a successfully studied and developed master - slave muld - microcomputers control system based on PC - BUS for hollow spindle fancy yarn spinning machine, mainly Its overall scheme, software and hardware construction, is introduced. Spinning experiments show that the system achieves satisfactory result. This system can solve the diftkultles of mechatronical fusion between domestic hollow splndk fancy yarn spuming muchine and its microcomputer control technology. 展开更多
关键词 hollow spinDLE FANCY YAM spinning machine mechatrvnical fusion MASTER - SLAVE MULTI - microcomputers control system PC - BUS.
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Influence of Rashba spin–orbit coupling on Josephson effect in triplet superconductor/two-dimensional semiconductor/triplet superconductor junctions
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作者 Bin-Hao Du Man-Ni Chen Liang-Bin Hu 《Chinese Physics B》 SCIE EI CAS CSCD 2022年第7期490-497,共8页
We study theoretically Josephson effect in a planar ballistic junction between two triplet superconductors with pwave orbital symmetries and separated by a two-dimensional(2D)semiconductor channel with strong Rashba s... We study theoretically Josephson effect in a planar ballistic junction between two triplet superconductors with pwave orbital symmetries and separated by a two-dimensional(2D)semiconductor channel with strong Rashba spin–orbit coupling.In triplet superconductors,three types of orbital symmetries are considered.We use Bogoliubov–de Gennes formalism to describe quasiparticle propagations through the junction and the supercurrents are calculated in terms of Andreev reflection coefficients.The features of the variation of the supercurrents with the change of the strength of Rashba spin–orbit coupling are investigated in some detail.It is found that for the three types of orbital symmetries considered,both the magnitudes of supercurrent and the current-phase relations can be manipulated effectively by tuning the strength of Rashba spin–orbit coupling.The interplay of Rashba spin–orbit coupling and Zeeman magnetic field on supercurrent is also investigated in some detail. 展开更多
关键词 Josephson effect Rashba spin–orbit coupling triplet superconductor 0-πtransitions
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Anomalous spin Josephson effect in spin superconductors
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作者 曾文 沈瑞 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期126-131,共6页
The spin superconductor state is the spin-polarized triplet exciton condensate,which can be viewed as a counterpart of the charge superconductor state.As an analogy of the charge Josephson effect,the spin Josephson ef... The spin superconductor state is the spin-polarized triplet exciton condensate,which can be viewed as a counterpart of the charge superconductor state.As an analogy of the charge Josephson effect,the spin Josephson effect can be generated in the spin superconductor/normal metal/spin superconductor junctions.Here we study the spin supercurrent in the Josephson junctions consisting of two spin superconductors with noncollinear spin polarizations.For the Josephson junctions with out-of-plane spin polarizations,the possibleπ-state spin supercurrent appears due to the Fermi momentum-splitting Andreev-like reflections at the normal metal/spin superconductor interfaces.For the Josephson junctions with in-plane spin polarizations,the anomalous spin supercurrent appears and is driven by the misorientation angle of the in-plane polarizations.The symmetry analysis shows that the appearance of the anomalous spin Josephson current is possible when the combined symmetry of the spin rotation and the time reversal is broken. 展开更多
关键词 tunneling junction spin supercurrent 0-πtransition anomalous spin Josephson effect
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Visualizing the Spin & Radiation of the Extended Electron in Magnetic Field
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作者 Hoa Van Nguyen 《Journal of High Energy Physics, Gravitation and Cosmology》 CAS 2024年第1期277-291,共15页
This article presents illustrations of an extended model of the electron to visualize how it spins and radiates in the external magnetic field. A time-varying magnetic field B produces a rotational induced electric fi... This article presents illustrations of an extended model of the electron to visualize how it spins and radiates in the external magnetic field. A time-varying magnetic field B produces a rotational induced electric field E which rotates (spins) the electron about its axis. In time-constant magnetic field: the electron radiates the cyclotron radiation. In time-varying magnetic field: synchrotron radiation is generated. The couplings between spin, acceleration and radiation will be discussed. 展开更多
关键词 spinning Forces spin by Inertia Radiating Forces Photon or Static Electric Dipole Cloud of Photons spin - Radiation Coupling
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Application of Rare Earth Spin Finishes Chloride on PET/PA Composite Super-fine Denier Fiber
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作者 车江宁 袁琴华 朱庆华 《Journal of China Textile University(English Edition)》 EI CAS 1998年第4期76-78,共3页
The primariy application of rare - earth spin finishes on PET/PA composite super - fine denier fiber has been studied in this paper. It results in the improvement of fi-ber’s properties, such as increased whiteness, ... The primariy application of rare - earth spin finishes on PET/PA composite super - fine denier fiber has been studied in this paper. It results in the improvement of fi-ber’s properties, such as increased whiteness, brightness and brilliance, effective and uniform spliting of compos-ite fiber into super - fine denier fiber and enhanced dye-ing effect. 展开更多
关键词 RARE earth COMPOSITE super - fine denier fiber spin finishes
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国家复杂产品生产能力——一个基于IPO范式的思考 被引量:2
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作者 李靖华 盛亚 《科技管理研究》 CSSCI 北大核心 2018年第24期120-126,共7页
从经济学"投入-生产-产出"(IPO)范式的过程视角,探讨以创新为核心思想的复杂产品生产能力(包括技术能力和管理能力),并构建从资源投入、组织范式到复杂产品生产,再到生产绩效产出的全过程能力分析框架。分析表明,国家复杂产... 从经济学"投入-生产-产出"(IPO)范式的过程视角,探讨以创新为核心思想的复杂产品生产能力(包括技术能力和管理能力),并构建从资源投入、组织范式到复杂产品生产,再到生产绩效产出的全过程能力分析框架。分析表明,国家复杂产品生产能力是一个系统,需要用系统思维方式构建更为宏大的理论;以及,更要体现政策研究的规范性、描述性和工具性的统一。 展开更多
关键词 复杂产品 生产能力 投入-生产-产出(ipo) 技术能力 管理能力
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基于委托—代理模型的公司IPO市场时机选择分析
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作者 孙文龙 《商业时代》 北大核心 2012年第3期70-71,共2页
本文将投资银行看作是公司IPO的委托代理人,根据委托—代理理论以及信号理论,得到了最优契约下公司IPO行为的特点,指出优质公司会先于劣质公司进行IPO,且优质公司的发行溢价要高于劣质公司的溢价。
关键词 ipo 委托-代理模型 发行溢价
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Deployment dynamics of a simplified spinning IKAROS solar sail via absolute coordinate based method 被引量:14
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作者 Jing Zhao Hai-Yan Hu Qiang Tian 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2013年第1期132-142,共11页
The spinning solar sail of large scale has been well developed in recent years. Such a solar sail can be considered as a rigid-flexible multibody system mainly composed of a spinning central rigid hub, a number of fle... The spinning solar sail of large scale has been well developed in recent years. Such a solar sail can be considered as a rigid-flexible multibody system mainly composed of a spinning central rigid hub, a number of flexible thin tethers, sail membranes, and tip masses. A simplified interplanetary kite-craft accelerated by radiation of the Sun (IKAROS) model is established in this study by using the absolute-coordinate-based (ACB) method that combines the natural coordinate formulation (NCF) describing the central rigid hub and the absolute nodal coordinate formulation (ANCF) describing flexible parts. The initial configuration of the system in the second-stage deployment is determined through both dynamic and static analyses. The huge set of stiff equations of system dynamics is solved by using the generalized-alpha method, and thus the deployment dynamics of the system can be well understood. 展开更多
关键词 Solar sail · spinning deployment - Natural coordinate formulation Absolute nodal coordinate formulation
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Entropy of Dilatonic Black Hole due to Arbitrary Spin Fields 被引量:1
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作者 You-Gen Shen and Chang-Jun Gao (Shanghai Astronomical Observatory, Chinese Academy of Sciences, Shanghai 200030 National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 Institute of Theoretical Physics, Chinese Academy of Scienc 《Chinese Journal of Astronomy and Astrophysics》 CSCD 北大核心 2001年第4期357-364,共8页
Using the membrane model based on the brick-wall model, we calculate the free energy and entropy of dilatonic black hole due to arbitrary spin fields. The result shows that the entropy of scalar field and the entropy ... Using the membrane model based on the brick-wall model, we calculate the free energy and entropy of dilatonic black hole due to arbitrary spin fields. The result shows that the entropy of scalar field and the entropy of Fermionic field have similar formulas. There is only a numerical coefficient between them. 展开更多
关键词 black hole physics - entropy - spin
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快速分析电大腔体电磁散射的混合算法 被引量:4
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作者 岳慧 高本庆 +1 位作者 李伟明 王学田 《电波科学学报》 EI CSCD 北大核心 2006年第2期161-165,共5页
为提高电大腔体电磁散射分析的效率,提出将迭代物理光学法(IPO)与快速多极子方法(FMM)相结合的混合算法IPO+FMM,给出该混合算法的数学模型推导,该算法可将每迭代步的计算量由O(N2)降到O(N1.5),最后分析了二种不同形状的电大尺寸腔体的... 为提高电大腔体电磁散射分析的效率,提出将迭代物理光学法(IPO)与快速多极子方法(FMM)相结合的混合算法IPO+FMM,给出该混合算法的数学模型推导,该算法可将每迭代步的计算量由O(N2)降到O(N1.5),最后分析了二种不同形状的电大尺寸腔体的雷达散射截面。数值结果表明,该混合算法与IPO算法相校,精度相当但效率有显著提高。 展开更多
关键词 快速多极子-迭代物理光学方法(ipo+FMM) 腔体 雷达散射截面(RCS)
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境外矿权资产注入—分拆上市的成功案例
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作者 杨玲玲 王京彬 《矿产勘查》 2013年第1期12-15,共4页
中色地科矿产勘查股份有限公司投资加拿大上市公司——加纳克资源公司,获得丰厚投资回报。2010年中色地科控股子公司——中色金地资源科技有限公司将其在埃塞俄比亚瑞丰公司70%的权益转让给加纳克公司,获取400万加元现金补偿和350万股... 中色地科矿产勘查股份有限公司投资加拿大上市公司——加纳克资源公司,获得丰厚投资回报。2010年中色地科控股子公司——中色金地资源科技有限公司将其在埃塞俄比亚瑞丰公司70%的权益转让给加纳克公司,获取400万加元现金补偿和350万股上市公司股票。之后,加纳克公司将注入的瑞丰矿权资产分拆上市,实现了资产价值的最大化,得到了市场的广泛认可。成功地探索了一条境外风险勘查投资退出和矿权资产证券化的新路子。 展开更多
关键词 境外勘查 矿权资产重组 分拆上市 中色地科公司
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Growth of ZnSe∶Mn Nanocrystals from Vapour Phase 被引量:1
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作者 O Senthil Kumar K Balkis Ameen S Soundeswaran T Rajasekharan R Dhanasekaran 《Journal of Rare Earths》 SCIE EI CAS CSCD 2006年第z1期111-114,共4页
ZnSe∶Mn nanocrystals were grown by chemical vapour transport method using the matrix of SiO2 aerogels. The cubic structure of the nanocrystals was confirmed by powder X-ray diffraction (XRD) and electron diffraction ... ZnSe∶Mn nanocrystals were grown by chemical vapour transport method using the matrix of SiO2 aerogels. The cubic structure of the nanocrystals was confirmed by powder X-ray diffraction (XRD) and electron diffraction (ED) studies. The size of the crystals was observed using transmission electron microscope (TEM). The oxidation state of Mn in ZnSe nanocrystal was found using electron spin resonance (ESR) spectrum. The room temperature luminescence measurements show the peaks corresponding to both bandgap of the material and Mn in ZnSe. 展开更多
关键词 - SEMICONDUCTORS NANOCRYSTALLINE materials electron spin RESONANCE
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Substituting Effect of Y in La_(0.5) Ba_(0.5) CoO_3
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作者 刘宜华 张汝贞 +3 位作者 王成建 岳龙强 季刚 梅良模 《Journal of Rare Earths》 SCIE EI CAS CSCD 2003年第3期347-350,共4页
La 0.5- x Y x Ba 0.5 CoO 3 polycrystals were prepared by solid state reaction. The substituting effects of Y for La on the magnetic and transport properties of the materials were studied systematically... La 0.5- x Y x Ba 0.5 CoO 3 polycrystals were prepared by solid state reaction. The substituting effects of Y for La on the magnetic and transport properties of the materials were studied systematically. The results indicate that substitution of Y induces two effects. Firstly, the charge transfer from Y to 3d orbital of Co happens. This causes the molecular magnetic moment to decrease. Secondly, the antiferromagnetic exchange interaction of Co ions appears. When the content of Y is less than or equal to 30%, the non colinear structure of spins in materials is observed. When the content of Y is greater than 30%, the materials transit from predominant ferromagnetic state to predominant antiferromagnetic one. The conductive mechanism for the materials with different content of Y belongs to the variable range hopping conduction of polarons. The resistivity of materials increases sharply with increasing Y content. 展开更多
关键词 La 0.5- x Y x Ba 0.5 CoO 3 compound charge transfer non colinear structure of spins variable range hopping conduction rare earths
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High spin states in stable nucleus ^(84)Sr 被引量:4
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作者 KANG XuZhong SHEN ShuiFa +6 位作者 HAN GuangBing PAN Feng GU JianZhong DRAAYER J P WU XiaoGuang ZHU LiHua WEN TingDun 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS 2010年第10期1861-1867,共7页
High spin states of 84Sr were populated through the reaction 70Zn(18O,4n)84Sr at 75 MeV beam energy.Measurement of excitation function,γ-γ coincidences,directional correlation from oriented state (DCO) ratios and γ... High spin states of 84Sr were populated through the reaction 70Zn(18O,4n)84Sr at 75 MeV beam energy.Measurement of excitation function,γ-γ coincidences,directional correlation from oriented state (DCO) ratios and γ-transition intensities were performed using eight anticompton HPGe detectors and one planar HPGe detector.Based on the measured results,a new level scheme of 84Sr was established in which 12 new states and nearly 30 new γ-transitions were identified in the present work.The positive-parity states of the new level scheme were compared with the results from calculations in the framework of the projected shell model (PSM).One negative-parity band was extended to spin Iπ=19-and it can be found that in the high spin states,the γ-transition energies show the nature of signature staggering.The negative-parity band levels are in good agreement with deformed configuration-mixing shell model (DCM) calculations. 展开更多
关键词 high spin states γ-γcoincidence DCO ratio level scheme PSM
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Generation of arbitrarily polarized GeV lepton beams via nonlinear Breit-Wheeler process 被引量:1
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作者 Kun Xue Ren-Tong Guo +7 位作者 Feng Wan Rashid Shaisultanov Yue-Yue Chen Zhong-Feng Xu Xue-Guang Ren Karen Z.Hatsagortsyan Christoph H.Keitel Jian-Xing Li 《Fundamental Research》 CAS 2022年第4期539-545,共7页
Generation of arbitrarily spin-polarized electron and positron beams has been investigated in the single-shot interaction of high-energy polarized r-photons with an ultraintense asymmetric laser pulse via nonlinear Br... Generation of arbitrarily spin-polarized electron and positron beams has been investigated in the single-shot interaction of high-energy polarized r-photons with an ultraintense asymmetric laser pulse via nonlinear Breit-Wheeler pair production.We develop a fully spin-resolved semi-classical Monte Carlo method to describe the pair creation and polarization.In the considered general setup,there are two sources of the polarization of created pairs:the spin angular momentum transfer from the polarized parent-photons,as well as the asymmetry and polarization of the driving laser field.This allows to develop a highly sensitive tool to control the polarization of created electrons and positrons.Thus,dense GeV lepton beams with average polarization degree up to about 80%,adjustable continuously between the transverse and longitudinal components,can be obtained by our all-optical method with currently achievable laser facilities,which could find an application as injectors of the polarized e^(+)e^(-)collider to search for new physics beyond the Standard Model. 展开更多
关键词 Nonlinear Breit-Wheeler pair production spin polarization Polarized positron beam Polarized e^(+)e^(-)collider
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再灌注损伤挽救激酶和线粒体膜通透性转换在肝缺血后处理中的作用 被引量:2
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作者 朱宇麟 李静 +1 位作者 吕毅 景桂霞 《中华实验外科杂志》 CAS CSCD 北大核心 2012年第5期975-976,共2页
缺血后处理(IPO)能减轻肝脏缺血再灌注损伤。我们通过观察缺血后处理对磷脂酰肌醇-3激酶(P13K)、细胞外信号调节激酶1/2(ERK1/2)和线粒体膜通透性转换(MPT)的影响,探讨肝脏IPO的作用机制。
关键词 肝脏缺血再灌注损伤 磷脂酰肌醇-3激酶 缺血后处理 通透性转换 线粒体膜 细胞外信号调节激酶1 ipo
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