This study introduces a new classifier tailored to address the limitations inherent in conventional classifiers such as K-nearest neighbor(KNN),random forest(RF),decision tree(DT),and support vector machine(SVM)for ar...This study introduces a new classifier tailored to address the limitations inherent in conventional classifiers such as K-nearest neighbor(KNN),random forest(RF),decision tree(DT),and support vector machine(SVM)for arrhythmia detection.The proposed classifier leverages the Chi-square distance as a primary metric,providing a specialized and original approach for precise arrhythmia detection.To optimize feature selection and refine the classifier’s performance,particle swarm optimization(PSO)is integrated with the Chi-square distance as a fitness function.This synergistic integration enhances the classifier’s capabilities,resulting in a substantial improvement in accuracy for arrhythmia detection.Experimental results demonstrate the efficacy of the proposed method,achieving a noteworthy accuracy rate of 98% with PSO,higher than 89% achieved without any previous optimization.The classifier outperforms machine learning(ML)and deep learning(DL)techniques,underscoring its reliability and superiority in the realm of arrhythmia classification.The promising results render it an effective method to support both academic and medical communities,offering an advanced and precise solution for arrhythmia detection in electrocardiogram(ECG)data.展开更多
Diabetes mellitus is a metabolic disease that is ranked among the top 10 causes of death by the world health organization.During the last few years,an alarming increase is observed worldwide with a 70%rise in the dise...Diabetes mellitus is a metabolic disease that is ranked among the top 10 causes of death by the world health organization.During the last few years,an alarming increase is observed worldwide with a 70%rise in the disease since 2000 and an 80%rise in male deaths.If untreated,it results in complications of many vital organs of the human body which may lead to fatality.Early detection of diabetes is a task of significant importance to start timely treatment.This study introduces a methodology for the classification of diabetic and normal people using an ensemble machine learning model and feature fusion of Chi-square and principal component analysis.An ensemble model,logistic tree classifier(LTC),is proposed which incorporates logistic regression and extra tree classifier through a soft voting mechanism.Experiments are also performed using several well-known machine learning algorithms to analyze their performance including logistic regression,extra tree classifier,AdaBoost,Gaussian naive Bayes,decision tree,random forest,and k nearest neighbor.In addition,several experiments are carried out using principal component analysis(PCA)and Chi-square(Chi-2)fea-tures to analyze the influence of feature selection on the performance of machine learning classifiers.Results indicate that Chi-2 features show high performance than both PCA features and original features.However,the highest accuracy is obtained when the proposed ensemble model LTC is used with the proposed fea-ture fusion framework-work which achieves a 0.85 accuracy score which is the highest of the available approaches for diabetes prediction.In addition,the statis-tical T-test proves the statistical significance of the proposed approach over other approaches.展开更多
The Rural Minimum Living Standard Guarantee(Rural Dibao)is an important unconditional cash transfer program to alleviate poverty in rural China.Despite the importance of children’s nutrition in breaking poverty cycle...The Rural Minimum Living Standard Guarantee(Rural Dibao)is an important unconditional cash transfer program to alleviate poverty in rural China.Despite the importance of children’s nutrition in breaking poverty cycles,little is known about the impact of Rural Dibao on child nutrition outcomes.Using China Family Panel Studies(CFPS),this paper examines the effects of Rural Dibao on child nutrition outcomes and investigates potential pathways and heterogeneous effects.We exploit propensity score matching and difference-in-differences techniques to evaluate the effects of the Rural Dibao program on child nutrition outcomes.Our results suggest that Rural Dibao significantly impacts the nutrition outcomes of children up to 15 years of age.Specifically,our results suggest that Rural Dibao improves child height-to-age z-scores by 1.05 standard deviations and lowers the probability of stunting by 11.9 percentage points.Additional analyses suggest that increased protein intake is the main pathway through which Rural Dibao participation contributes to better nutrition outcomes.We also find that the effect of the program is more pronounced among girls,children who are non-left-behind or live with highly educated mothers,and those from low-income families and poor areas.Our findings suggest that Rural Dibao participation helps improve child nutrition outcomes through improving diet quality.展开更多
Background:The Mongolian gerbil is an excellent laboratory animal for preparing the cerebral ischemia model due to its inherent deficiency in the circle of Willis.However,the low incidence and unpredictability of symp...Background:The Mongolian gerbil is an excellent laboratory animal for preparing the cerebral ischemia model due to its inherent deficiency in the circle of Willis.However,the low incidence and unpredictability of symptoms are caused by numerous complex variant types of the circle.Additionally,the lack of an evaluation system for the cer-ebral ischemia/reperfusion(I/R)model of gerbils has shackled the application of this model.Methods:We created a symptom-oriented principle and detailed neurobehavioral scoring criteria.At different time points of reperfusion,we analyzed the alteration in locomotion by rotarod test and grip force score,infarct volume by triphenyltetrazo-lium chloride(TTC)staining,neuron loss using Nissl staining,and histological charac-teristics using hematoxylin-eosin(H&E)straining.Results:With a successful model rate of 56%,32 of the 57 gerbils operated by our method harbored typical features of cerebral I/R injury,and the mortality rate in the male gerbils was significantly higher than that in the female gerbils.The suc-cessfully prepared I/R gerbils demonstrated a significant reduction in motility and grip strength at 1 day after reperfusion;formed obvious infarction;exhibited typi-cal pathological features,such as tissue edema,neuronal atrophy and death,and vacuolated structures;and were partially recovered with the extension of reperfu-sion time.Conclusion:This study developed a new method for the unilateral common carotid artery ligation I/R model of gerbil and established a standardized evaluation system for this model,which could provide a new cerebral I/R model of gerbils with more practical applications.展开更多
Background Two studies were designed to determine standard ileal crude protein(CP)and amino acid(AA)digestibility of soybean meal(SBM)from different origins fed to non-pregnant and pregnant sows.Seven solvent-extracte...Background Two studies were designed to determine standard ileal crude protein(CP)and amino acid(AA)digestibility of soybean meal(SBM)from different origins fed to non-pregnant and pregnant sows.Seven solvent-extracted SBMs from soybeans produced in the USA,Brazil,and China were selected.In Exp.1,eight different diets were created:a nitrogen(N)-free diet and 7 experimental diets containing SBM from different origins as the only N source.Eight non-pregnant,multiparous sows were arranged in an 8×8 Latin square design(8 periods and 8 diets).In Exp.2,the diet formula was the same as in Exp.1.Eight gestating sows(parity 3)were assigned to 4 different diets in a replicated 4×3 Youden square design(three periods and four diets)in mid-gestation and again in late-gestation stages.Results When fed to non-pregnant and late-gestating sows,the standardized ileal digestibility(SID)of CP and most AAs from different SBM were not significantly different(P>0.05).When fed to mid-gestating sows,the SID values for Arg,His,Lys,Phe,Cys,Gly,Ser,and Tyr in SBM 1 were lower than in SBM 4 and 5(P<0.05),whereas SID for Leu from SBM 5 was higher than in SBM 1 and 4(P<0.05).SID values for Ile,Ala,and Asp from SBM 4 were lower than in SBM 1 and 5(P<0.05).Sows had significantly greater SID values for Lys,Ala,and Asp during mid-gestation when compared with late-gestation stages(P<0.05).Mid-gestating sows had greater SID value for Val and lower SID value for Tyr when compared with non-pregnant and late-gestating sows(P<0.01),whereas non-pregnant sows had significantly greater SID value for Met when compared with gestating sows(P<0.01).Conclusions When fed to mid-gestating sows,the SID values for most AAs varied among SBM samples.The SID values for Lys,Met,Val,Ala,Asp,and Tyr in SBM were affected by sow gestation stages.Our findings provide a cornerstone for accurate SBM use in sow diets.展开更多
This study proposes a batch rapid quantitative analysis method for multiple elements by combining the advantages of standard curve(SC)and calibration-free laser-induced breakdown spectroscopy(CF-LIBS)technology to ach...This study proposes a batch rapid quantitative analysis method for multiple elements by combining the advantages of standard curve(SC)and calibration-free laser-induced breakdown spectroscopy(CF-LIBS)technology to achieve synchronous,rapid,and accurate measurement of elements in a large number of samples,namely,SC-assisted CF-LIBS.Al alloy standard samples,divided into calibration and test samples,were applied to validate the proposed method.SC was built based on the characteristic line of Pb and Cr in the calibration sample,and the contents of Pb and Cr in the test sample were calculated with relative errors of 6%and 4%,respectively.SC built using Cr with multiple characteristic lines yielded better calculation results.The relative contents of ten elements in the test sample were calculated using CF-LIBS.Subsequently,the SC-assisted CF-LIBS was executed,with the majority of the calculation relative errors falling within the range of 2%-5%.Finally,the Al and Na contents of the Al alloy were predicted.The results demonstrate that it effectively enables the rapid and accurate quantitative analysis of multiple elements after a single-element SC analysis of the tested samples.Furthermore,this quantitative analysis method was successfully applied to soil and Astragalus samples,realizing an accurate calculation of the contents of multiple elements.Thus,it is important to advance the LIBS quantitative analysis and its related applications.展开更多
Introduction: Resistance to antituberculosis drugs and adverse drug reactions remain the leading causes of tuberculosis therapeutic failure globally. Despite the increasing acceptance of medicinal plant use in combina...Introduction: Resistance to antituberculosis drugs and adverse drug reactions remain the leading causes of tuberculosis therapeutic failure globally. Despite the increasing acceptance of medicinal plant use in combination with conventional antituberculosis drugs in treatment of tuberculosis (TB) in Uganda, there is paucity of knowledge on their combination effect. Aim: This research aimed to determine combination activity of standard antituberculosis drugs with extracts of Zanthoxylum leprieurii Guill. & Perr. and Rubia cordifolia L., the two common antituberculosis medicinal plants in Uganda, against pansensitive (H37Rv) and multi-drug resistant (MDR) Mycobacterium tuberculosis strains. Materials and Methods: Two reference MTB strains (H37Rv and MDR strain) were inoculated on Middlebrook 7H11 medium containing a combination of standard antituberculosis drugs and methanol extracts of Z. leprieurii and R. cordifolia at varying concentrations. The number of colonies on the plates was observed and counted weekly for up to 8 weeks. In vitro combination activity was determined using proportion method. Mean percentage inhibition was calculated for the reduction of number of colonies on drug-extract combination medium in relation to drug-extract-free control medium. Results: Drug-extract combinations showed good combination activity against Mycobacterium tuberculosis strains when compared with individual standard anti-TB drugs. This was more exhibited against MDR strain. There was however a reduction in percentage inhibition when extracts were combined with ethambutol and streptomycin against H37Rv strain. Conclusions: Zanthoxylum leprieurii and Rubia cordifolia in combination with standard anti-TB drugs exhibited increased in vitro activity against Mycobacterium tuberculosis, especially MDR-TB strain. This justifies the local use of these plants in traditional treatment of tuberculosis especially in resistant cases in Uganda.展开更多
Sichuan province is home to rich traditional Chinese medicine(TCM)resources.Recent years have seen unremitting efforts of TCM standardization in the province.By analyzing the measures and existing problems,this paper ...Sichuan province is home to rich traditional Chinese medicine(TCM)resources.Recent years have seen unremitting efforts of TCM standardization in the province.By analyzing the measures and existing problems,this paper provides recommendations to boost TCM development through standardization.展开更多
AIM:To develop normative data for meibomian gland dysfunction(MGD)parameters,using non-contact meibography technique of Sirius Costruzione Strumenti Oftalmici(CSO)machine,in an Egyptian population sample.METHODS:Obser...AIM:To develop normative data for meibomian gland dysfunction(MGD)parameters,using non-contact meibography technique of Sirius Costruzione Strumenti Oftalmici(CSO)machine,in an Egyptian population sample.METHODS:Observational,cross-sectional,analytic study,in which 104 Egyptian volunteers were included.Both upper lids were examined,using“Sirius CSO”machine.Each eyelid was given a degree of meibomian gland loss(MGL),which was calculated by the software of the machine.RESULTS:Mean percentage MGL in right upper lid was of 30.9%±12.6%,and that of left upper lid was 32.6%±11.8%.Thirty-four volunteers(32.7%)had first-degree MGL in their right upper lid,and 67.3%had second-degree loss.One volunteer(1%)had zero-degree MGL in left upper lid,28(26.9%)had first-degree loss,and 75(72.1%)had second-degree loss.Degree of MGL in right upper eyelid was not related to age,but degree of MGL in left upper eyelid increased with age.There was statistically significant difference between both genders for degree of MGL in right eye(P=0.036)and in left eye(P=0.027).CONCLUSION:Noncontact meibography is a useful non-invasive tool for diagnosing MGL.MGL is diagnosed in 100%of apparently normal individuals;26.9%-32.7%of which have first-degree MGL,and 67.3%-72.1%have second-degree MGL.展开更多
This part of the study aims to evaluate the advantages and disadvantages of technical standards of screw conveyors in China,Germany,and the USA for industrial applications.The source or determination method of empiric...This part of the study aims to evaluate the advantages and disadvantages of technical standards of screw conveyors in China,Germany,and the USA for industrial applications.The source or determination method of empirical coefficients as well as the theoretical foundation of dimensioning-relevant diagrams in these standards is not explicitly documented in the literature.Therefore,instead of less efficient on-site tests,the numerical simulation by discrete element method is conducted.Based on the geometrical and operational designs determined in three standards for horizontal,slightly inclined,and vertical conveyance of three representative bulk solids(barley,lignite,and sand),the potential influencing factors are discussed.With constant particle and contact parameters,the potential deviations caused by particle models are eliminated.Furthermore,the accuracy of power consumption calculation of each standard and the divergence between accessible and required mass flows is comprehensively assessed based on the analysis of simulated outcomes.Two main conclusions are drawn:(1)Particle fall back is barely considered by all three standards and leads to overestimated mass throughput;(2)The decrease in mass throughput caused by an increasing degree of filling can be compensated by slowing down the rotational speed.展开更多
A numerical approach is an effective means of solving boundary value problems(BVPs).This study focuses on physical problems with general partial differential equations(PDEs).It investigates the solution approach throu...A numerical approach is an effective means of solving boundary value problems(BVPs).This study focuses on physical problems with general partial differential equations(PDEs).It investigates the solution approach through the standard forms of the PDE module in COMSOL.Two typical mechanics problems are exemplified:The deflection of a thin plate,which can be addressed with the dedicated finite element module,and the stress of a pure bending beamthat cannot be tackled.The procedure for the two problems regarding the three standard forms required by the PDE module is detailed.The results were in good agreement with the literature,indicating that the PDE module provides a promising means to solve complex PDEs,especially for those a dedicated finite element module has yet to be developed.展开更多
Given the rapid development of China’s new urbanization,cities with different locations and varying functional positioning,resource endowments,and development stages have insufficient scientific and applicable techni...Given the rapid development of China’s new urbanization,cities with different locations and varying functional positioning,resource endowments,and development stages have insufficient scientific and applicable technical tools for implementing the United Nations Sustainable Development Goals(SDGs).City managers and policymakers must urgently establish SDG benchmarks to diagnose city development.Moreover,successful experiences from similar cities regarding sustainable development and self-improvement must be learned from to promote diversified,sustainable development across the country.Furthermore,emerging technologies such as artificial intelligence,the Internet of Things,big data and 5G are widely used in smart cities.Therefore,there is a growing need for“knowledge-based,personalized and intelligent”technologies to support monitoring,evaluation,and decision-making processes facilitating sustainable development in cities.This paper uses standardization as the theoretical support and technical basis.This approach can help clarify the sustainable development processes in China and clarify the evaluation results of and provide data on horizontal city comparisons,which can be used to develop evaluation technology for sustainable development in cities and construct a standardized system.The results provide a standard framework for intelligent assessment and decision-making regarding cities’sustainable development capabilities in China.Evaluating major international standardization institutions reveals that the practices of Chinese national standards should be fully absorbed and integrated to guide the evaluation of smart,resilient,and low-carbon cities.To this end,an indicator library of city sustainable development is proposed to provide standard evaluation technology methods.Finally,analyzing the response relationship of the indicator library to SDGs reveals the need for a standardized knowledge map of sustainable development assessment techniques and methods from the perspective of integrated management for sustainable development in cities.展开更多
To probe into the directions and difficulties of standardization discipline construction in China,China Standardization Press organized a pertinent dialogue on July 10.During the event,Yu Xinli,President of China Asso...To probe into the directions and difficulties of standardization discipline construction in China,China Standardization Press organized a pertinent dialogue on July 10.During the event,Yu Xinli,President of China Association for Standardization,was invited as the moderator.Several standardization experts including Song Mingshun,Mai Lyubo,Qiang Yi,Cao Lili,and Huang Manxue from the China Standardization Expert Committee and renowned universities and research institutes in the country were invited as guests to give their insightful views.展开更多
We focus on the importance and necessity of post-competency-based training in medical education alongside its current challenges and opportunities.Integrating post competency training into standardized educational fra...We focus on the importance and necessity of post-competency-based training in medical education alongside its current challenges and opportunities.Integrating post competency training into standardized educational frameworks is increasingly recognized as a critical component of preparing residents and postgraduates for real-world clinical practice.Post competency training represents a commitment to excellence in medical education,striving to produce competent,skilled practitioners to meet the challenges of modern healthcare.展开更多
The Chengdu community security funds refer to the special security funds for urban and rural community development and governance in Chengdu.At present,there are some problems in the use of community security funds,su...The Chengdu community security funds refer to the special security funds for urban and rural community development and governance in Chengdu.At present,there are some problems in the use of community security funds,such as low participation of residents,and low efficiency of fund use.Taking the exploration of standardization of community security fund management in Wuhou district,Chengdu city,as an example,this paper suggests further strengthening the use and management of community security funds by means of standardization,ensuring the democratic,open,and transparent use of funds,and effectively enhancing the supporting role of community security funds in community governance.展开更多
With the support of the Belgian FPS Economy,SBS and CEN-CENELEC are co-organizing the workshop,under the High-Level Forum on European standardization(HLF)and its workstream on inclusiveness in national standardization...With the support of the Belgian FPS Economy,SBS and CEN-CENELEC are co-organizing the workshop,under the High-Level Forum on European standardization(HLF)and its workstream on inclusiveness in national standardization,to tackle issues of access and participation in standardization at the national level and discuss and promote best practices.展开更多
The session on marine standardization was successfully held on May 22.Yu Xinli,President of China Association for Standardization(CAS),was invited to deliver a keynote speech.The highlight of her speech is presented a...The session on marine standardization was successfully held on May 22.Yu Xinli,President of China Association for Standardization(CAS),was invited to deliver a keynote speech.The highlight of her speech is presented as follows。展开更多
Witnessed by Chinese Premier Li Qiang and Sri Lanka Prime Minister Dinesh Gunawardena,Luo Wen,Minister of SAMR,and Anura Dissanayake,Secretary to the Prime Minster of Sri Lanka,signed a MoU on the standardization area...Witnessed by Chinese Premier Li Qiang and Sri Lanka Prime Minister Dinesh Gunawardena,Luo Wen,Minister of SAMR,and Anura Dissanayake,Secretary to the Prime Minster of Sri Lanka,signed a MoU on the standardization area on March 26.展开更多
From the perspective of group standards, the dynamics of the cosmetic industry in the past few years were briefly reviewed and analyzed, including the number of group standards published, types of group standards, gro...From the perspective of group standards, the dynamics of the cosmetic industry in the past few years were briefly reviewed and analyzed, including the number of group standards published, types of group standards, groups, and geographical distribution of the groups. The large number of participating groups and the wide range of geographical distribution indicated that group standards could play a positive role in the sustained and positive development of cosmetic industry. The future development of cosmetic industry was also prospected。展开更多
The deteriorated continuous rigid frame bridge is strengthened by external prestressing. Static loading tests wereconducted before and after the bridge rehabilitation to verify the effectiveness of the rehabilitation ...The deteriorated continuous rigid frame bridge is strengthened by external prestressing. Static loading tests wereconducted before and after the bridge rehabilitation to verify the effectiveness of the rehabilitation process. Thestiffness of the repaired bridge is improved, and the maximum deflection of the load test is reduced from 37.9 to27.6 mm. A bridge health monitoring system is installed after the bridge is reinforced. To achieve an easy assessmentof the bridge’s safety status by directly using transferred data, a real-time safety warning system is createdbased on a five-level safety standard. The threshold for each safety level will be determined by theoretical calculationsand the outcomes of static loading tests. The highest risk threshold will be set at the ultimate limit statevalue. The remaining levels, namely middle risk, low risk, and very low risk, will be determined usingreduction coefficients of 0.95, 0.9, and 0.8, respectively.展开更多
文摘This study introduces a new classifier tailored to address the limitations inherent in conventional classifiers such as K-nearest neighbor(KNN),random forest(RF),decision tree(DT),and support vector machine(SVM)for arrhythmia detection.The proposed classifier leverages the Chi-square distance as a primary metric,providing a specialized and original approach for precise arrhythmia detection.To optimize feature selection and refine the classifier’s performance,particle swarm optimization(PSO)is integrated with the Chi-square distance as a fitness function.This synergistic integration enhances the classifier’s capabilities,resulting in a substantial improvement in accuracy for arrhythmia detection.Experimental results demonstrate the efficacy of the proposed method,achieving a noteworthy accuracy rate of 98% with PSO,higher than 89% achieved without any previous optimization.The classifier outperforms machine learning(ML)and deep learning(DL)techniques,underscoring its reliability and superiority in the realm of arrhythmia classification.The promising results render it an effective method to support both academic and medical communities,offering an advanced and precise solution for arrhythmia detection in electrocardiogram(ECG)data.
基金supported by the Florida Center for Advanced Analytics and Data Science funded by Ernesto.Net(under the Algorithms for Good Grant).
文摘Diabetes mellitus is a metabolic disease that is ranked among the top 10 causes of death by the world health organization.During the last few years,an alarming increase is observed worldwide with a 70%rise in the disease since 2000 and an 80%rise in male deaths.If untreated,it results in complications of many vital organs of the human body which may lead to fatality.Early detection of diabetes is a task of significant importance to start timely treatment.This study introduces a methodology for the classification of diabetic and normal people using an ensemble machine learning model and feature fusion of Chi-square and principal component analysis.An ensemble model,logistic tree classifier(LTC),is proposed which incorporates logistic regression and extra tree classifier through a soft voting mechanism.Experiments are also performed using several well-known machine learning algorithms to analyze their performance including logistic regression,extra tree classifier,AdaBoost,Gaussian naive Bayes,decision tree,random forest,and k nearest neighbor.In addition,several experiments are carried out using principal component analysis(PCA)and Chi-square(Chi-2)fea-tures to analyze the influence of feature selection on the performance of machine learning classifiers.Results indicate that Chi-2 features show high performance than both PCA features and original features.However,the highest accuracy is obtained when the proposed ensemble model LTC is used with the proposed fea-ture fusion framework-work which achieves a 0.85 accuracy score which is the highest of the available approaches for diabetes prediction.In addition,the statis-tical T-test proves the statistical significance of the proposed approach over other approaches.
基金The authors are grateful for support from the National Social Science Fund of China(21AJL015).
文摘The Rural Minimum Living Standard Guarantee(Rural Dibao)is an important unconditional cash transfer program to alleviate poverty in rural China.Despite the importance of children’s nutrition in breaking poverty cycles,little is known about the impact of Rural Dibao on child nutrition outcomes.Using China Family Panel Studies(CFPS),this paper examines the effects of Rural Dibao on child nutrition outcomes and investigates potential pathways and heterogeneous effects.We exploit propensity score matching and difference-in-differences techniques to evaluate the effects of the Rural Dibao program on child nutrition outcomes.Our results suggest that Rural Dibao significantly impacts the nutrition outcomes of children up to 15 years of age.Specifically,our results suggest that Rural Dibao improves child height-to-age z-scores by 1.05 standard deviations and lowers the probability of stunting by 11.9 percentage points.Additional analyses suggest that increased protein intake is the main pathway through which Rural Dibao participation contributes to better nutrition outcomes.We also find that the effect of the program is more pronounced among girls,children who are non-left-behind or live with highly educated mothers,and those from low-income families and poor areas.Our findings suggest that Rural Dibao participation helps improve child nutrition outcomes through improving diet quality.
基金National Key Research and Development Program of China,Grant/Award Number:2021YFF0702402National Natural Science Foundation of China,Grant/Award Number:32070531。
文摘Background:The Mongolian gerbil is an excellent laboratory animal for preparing the cerebral ischemia model due to its inherent deficiency in the circle of Willis.However,the low incidence and unpredictability of symptoms are caused by numerous complex variant types of the circle.Additionally,the lack of an evaluation system for the cer-ebral ischemia/reperfusion(I/R)model of gerbils has shackled the application of this model.Methods:We created a symptom-oriented principle and detailed neurobehavioral scoring criteria.At different time points of reperfusion,we analyzed the alteration in locomotion by rotarod test and grip force score,infarct volume by triphenyltetrazo-lium chloride(TTC)staining,neuron loss using Nissl staining,and histological charac-teristics using hematoxylin-eosin(H&E)straining.Results:With a successful model rate of 56%,32 of the 57 gerbils operated by our method harbored typical features of cerebral I/R injury,and the mortality rate in the male gerbils was significantly higher than that in the female gerbils.The suc-cessfully prepared I/R gerbils demonstrated a significant reduction in motility and grip strength at 1 day after reperfusion;formed obvious infarction;exhibited typi-cal pathological features,such as tissue edema,neuronal atrophy and death,and vacuolated structures;and were partially recovered with the extension of reperfu-sion time.Conclusion:This study developed a new method for the unilateral common carotid artery ligation I/R model of gerbil and established a standardized evaluation system for this model,which could provide a new cerebral I/R model of gerbils with more practical applications.
基金funded by the National Key R&D Program of China(No.2021YFD1300202)the nutritional value evaluation and parameter establishment of protein feedstuffs for sowsthe Ministry of Agriculture and Rural Affairs of the People’s Republic of China(125D0203-16190295)the Major Scientific and Technological Special Project of Sichuan Province(No.2021ZDZX0009)。
文摘Background Two studies were designed to determine standard ileal crude protein(CP)and amino acid(AA)digestibility of soybean meal(SBM)from different origins fed to non-pregnant and pregnant sows.Seven solvent-extracted SBMs from soybeans produced in the USA,Brazil,and China were selected.In Exp.1,eight different diets were created:a nitrogen(N)-free diet and 7 experimental diets containing SBM from different origins as the only N source.Eight non-pregnant,multiparous sows were arranged in an 8×8 Latin square design(8 periods and 8 diets).In Exp.2,the diet formula was the same as in Exp.1.Eight gestating sows(parity 3)were assigned to 4 different diets in a replicated 4×3 Youden square design(three periods and four diets)in mid-gestation and again in late-gestation stages.Results When fed to non-pregnant and late-gestating sows,the standardized ileal digestibility(SID)of CP and most AAs from different SBM were not significantly different(P>0.05).When fed to mid-gestating sows,the SID values for Arg,His,Lys,Phe,Cys,Gly,Ser,and Tyr in SBM 1 were lower than in SBM 4 and 5(P<0.05),whereas SID for Leu from SBM 5 was higher than in SBM 1 and 4(P<0.05).SID values for Ile,Ala,and Asp from SBM 4 were lower than in SBM 1 and 5(P<0.05).Sows had significantly greater SID values for Lys,Ala,and Asp during mid-gestation when compared with late-gestation stages(P<0.05).Mid-gestating sows had greater SID value for Val and lower SID value for Tyr when compared with non-pregnant and late-gestating sows(P<0.01),whereas non-pregnant sows had significantly greater SID value for Met when compared with gestating sows(P<0.01).Conclusions When fed to mid-gestating sows,the SID values for most AAs varied among SBM samples.The SID values for Lys,Met,Val,Ala,Asp,and Tyr in SBM were affected by sow gestation stages.Our findings provide a cornerstone for accurate SBM use in sow diets.
基金supported by the Major Science and TechnologyTechnol-ogy Projects in Gansu Province(No.22ZD6FA021-5)Industrial Support Project of Gansu Province(Nos.2023CYZC-19 and 2021CYZC-22)+1 种基金Science and Technol-ogy Project of Gansu Province(Nos.23YFFA0074,22JR5RA137,and 22JR5RA151)Central Leading Local Science and Technology Development Fund Projects(No.23ZYQA293).
文摘This study proposes a batch rapid quantitative analysis method for multiple elements by combining the advantages of standard curve(SC)and calibration-free laser-induced breakdown spectroscopy(CF-LIBS)technology to achieve synchronous,rapid,and accurate measurement of elements in a large number of samples,namely,SC-assisted CF-LIBS.Al alloy standard samples,divided into calibration and test samples,were applied to validate the proposed method.SC was built based on the characteristic line of Pb and Cr in the calibration sample,and the contents of Pb and Cr in the test sample were calculated with relative errors of 6%and 4%,respectively.SC built using Cr with multiple characteristic lines yielded better calculation results.The relative contents of ten elements in the test sample were calculated using CF-LIBS.Subsequently,the SC-assisted CF-LIBS was executed,with the majority of the calculation relative errors falling within the range of 2%-5%.Finally,the Al and Na contents of the Al alloy were predicted.The results demonstrate that it effectively enables the rapid and accurate quantitative analysis of multiple elements after a single-element SC analysis of the tested samples.Furthermore,this quantitative analysis method was successfully applied to soil and Astragalus samples,realizing an accurate calculation of the contents of multiple elements.Thus,it is important to advance the LIBS quantitative analysis and its related applications.
文摘Introduction: Resistance to antituberculosis drugs and adverse drug reactions remain the leading causes of tuberculosis therapeutic failure globally. Despite the increasing acceptance of medicinal plant use in combination with conventional antituberculosis drugs in treatment of tuberculosis (TB) in Uganda, there is paucity of knowledge on their combination effect. Aim: This research aimed to determine combination activity of standard antituberculosis drugs with extracts of Zanthoxylum leprieurii Guill. & Perr. and Rubia cordifolia L., the two common antituberculosis medicinal plants in Uganda, against pansensitive (H37Rv) and multi-drug resistant (MDR) Mycobacterium tuberculosis strains. Materials and Methods: Two reference MTB strains (H37Rv and MDR strain) were inoculated on Middlebrook 7H11 medium containing a combination of standard antituberculosis drugs and methanol extracts of Z. leprieurii and R. cordifolia at varying concentrations. The number of colonies on the plates was observed and counted weekly for up to 8 weeks. In vitro combination activity was determined using proportion method. Mean percentage inhibition was calculated for the reduction of number of colonies on drug-extract combination medium in relation to drug-extract-free control medium. Results: Drug-extract combinations showed good combination activity against Mycobacterium tuberculosis strains when compared with individual standard anti-TB drugs. This was more exhibited against MDR strain. There was however a reduction in percentage inhibition when extracts were combined with ethambutol and streptomycin against H37Rv strain. Conclusions: Zanthoxylum leprieurii and Rubia cordifolia in combination with standard anti-TB drugs exhibited increased in vitro activity against Mycobacterium tuberculosis, especially MDR-TB strain. This justifies the local use of these plants in traditional treatment of tuberculosis especially in resistant cases in Uganda.
文摘Sichuan province is home to rich traditional Chinese medicine(TCM)resources.Recent years have seen unremitting efforts of TCM standardization in the province.By analyzing the measures and existing problems,this paper provides recommendations to boost TCM development through standardization.
文摘AIM:To develop normative data for meibomian gland dysfunction(MGD)parameters,using non-contact meibography technique of Sirius Costruzione Strumenti Oftalmici(CSO)machine,in an Egyptian population sample.METHODS:Observational,cross-sectional,analytic study,in which 104 Egyptian volunteers were included.Both upper lids were examined,using“Sirius CSO”machine.Each eyelid was given a degree of meibomian gland loss(MGL),which was calculated by the software of the machine.RESULTS:Mean percentage MGL in right upper lid was of 30.9%±12.6%,and that of left upper lid was 32.6%±11.8%.Thirty-four volunteers(32.7%)had first-degree MGL in their right upper lid,and 67.3%had second-degree loss.One volunteer(1%)had zero-degree MGL in left upper lid,28(26.9%)had first-degree loss,and 75(72.1%)had second-degree loss.Degree of MGL in right upper eyelid was not related to age,but degree of MGL in left upper eyelid increased with age.There was statistically significant difference between both genders for degree of MGL in right eye(P=0.036)and in left eye(P=0.027).CONCLUSION:Noncontact meibography is a useful non-invasive tool for diagnosing MGL.MGL is diagnosed in 100%of apparently normal individuals;26.9%-32.7%of which have first-degree MGL,and 67.3%-72.1%have second-degree MGL.
基金the European Union's Horizon 2020 Program(H2020/2014–2020)under grant agreement No.654446.
文摘This part of the study aims to evaluate the advantages and disadvantages of technical standards of screw conveyors in China,Germany,and the USA for industrial applications.The source or determination method of empirical coefficients as well as the theoretical foundation of dimensioning-relevant diagrams in these standards is not explicitly documented in the literature.Therefore,instead of less efficient on-site tests,the numerical simulation by discrete element method is conducted.Based on the geometrical and operational designs determined in three standards for horizontal,slightly inclined,and vertical conveyance of three representative bulk solids(barley,lignite,and sand),the potential influencing factors are discussed.With constant particle and contact parameters,the potential deviations caused by particle models are eliminated.Furthermore,the accuracy of power consumption calculation of each standard and the divergence between accessible and required mass flows is comprehensively assessed based on the analysis of simulated outcomes.Two main conclusions are drawn:(1)Particle fall back is barely considered by all three standards and leads to overestimated mass throughput;(2)The decrease in mass throughput caused by an increasing degree of filling can be compensated by slowing down the rotational speed.
基金supported by the National Natural Science Foundations of China(Grant Nos.12372073 and U20B2013)the Natural Science Basic Research Program of Shaanxi(Program No.2023-JC-QN-0030).
文摘A numerical approach is an effective means of solving boundary value problems(BVPs).This study focuses on physical problems with general partial differential equations(PDEs).It investigates the solution approach through the standard forms of the PDE module in COMSOL.Two typical mechanics problems are exemplified:The deflection of a thin plate,which can be addressed with the dedicated finite element module,and the stress of a pure bending beamthat cannot be tackled.The procedure for the two problems regarding the three standard forms required by the PDE module is detailed.The results were in good agreement with the literature,indicating that the PDE module provides a promising means to solve complex PDEs,especially for those a dedicated finite element module has yet to be developed.
基金supported by the National Key Research and Development Program of China under the theme“Research on urban sustainable development interactive decision-making and management technologies”[Grant No.2022YFC3802904].
文摘Given the rapid development of China’s new urbanization,cities with different locations and varying functional positioning,resource endowments,and development stages have insufficient scientific and applicable technical tools for implementing the United Nations Sustainable Development Goals(SDGs).City managers and policymakers must urgently establish SDG benchmarks to diagnose city development.Moreover,successful experiences from similar cities regarding sustainable development and self-improvement must be learned from to promote diversified,sustainable development across the country.Furthermore,emerging technologies such as artificial intelligence,the Internet of Things,big data and 5G are widely used in smart cities.Therefore,there is a growing need for“knowledge-based,personalized and intelligent”technologies to support monitoring,evaluation,and decision-making processes facilitating sustainable development in cities.This paper uses standardization as the theoretical support and technical basis.This approach can help clarify the sustainable development processes in China and clarify the evaluation results of and provide data on horizontal city comparisons,which can be used to develop evaluation technology for sustainable development in cities and construct a standardized system.The results provide a standard framework for intelligent assessment and decision-making regarding cities’sustainable development capabilities in China.Evaluating major international standardization institutions reveals that the practices of Chinese national standards should be fully absorbed and integrated to guide the evaluation of smart,resilient,and low-carbon cities.To this end,an indicator library of city sustainable development is proposed to provide standard evaluation technology methods.Finally,analyzing the response relationship of the indicator library to SDGs reveals the need for a standardized knowledge map of sustainable development assessment techniques and methods from the perspective of integrated management for sustainable development in cities.
文摘To probe into the directions and difficulties of standardization discipline construction in China,China Standardization Press organized a pertinent dialogue on July 10.During the event,Yu Xinli,President of China Association for Standardization,was invited as the moderator.Several standardization experts including Song Mingshun,Mai Lyubo,Qiang Yi,Cao Lili,and Huang Manxue from the China Standardization Expert Committee and renowned universities and research institutes in the country were invited as guests to give their insightful views.
基金Supported by Education and Teaching Reform Project of the First Clinical College of Chongqing Medical University,No.CMER202305Program for Youth Innovation in Future Medicine,Chongqing Medical University,No.W0138.
文摘We focus on the importance and necessity of post-competency-based training in medical education alongside its current challenges and opportunities.Integrating post competency training into standardized educational frameworks is increasingly recognized as a critical component of preparing residents and postgraduates for real-world clinical practice.Post competency training represents a commitment to excellence in medical education,striving to produce competent,skilled practitioners to meet the challenges of modern healthcare.
文摘The Chengdu community security funds refer to the special security funds for urban and rural community development and governance in Chengdu.At present,there are some problems in the use of community security funds,such as low participation of residents,and low efficiency of fund use.Taking the exploration of standardization of community security fund management in Wuhou district,Chengdu city,as an example,this paper suggests further strengthening the use and management of community security funds by means of standardization,ensuring the democratic,open,and transparent use of funds,and effectively enhancing the supporting role of community security funds in community governance.
文摘With the support of the Belgian FPS Economy,SBS and CEN-CENELEC are co-organizing the workshop,under the High-Level Forum on European standardization(HLF)and its workstream on inclusiveness in national standardization,to tackle issues of access and participation in standardization at the national level and discuss and promote best practices.
文摘The session on marine standardization was successfully held on May 22.Yu Xinli,President of China Association for Standardization(CAS),was invited to deliver a keynote speech.The highlight of her speech is presented as follows。
文摘Witnessed by Chinese Premier Li Qiang and Sri Lanka Prime Minister Dinesh Gunawardena,Luo Wen,Minister of SAMR,and Anura Dissanayake,Secretary to the Prime Minster of Sri Lanka,signed a MoU on the standardization area on March 26.
文摘From the perspective of group standards, the dynamics of the cosmetic industry in the past few years were briefly reviewed and analyzed, including the number of group standards published, types of group standards, groups, and geographical distribution of the groups. The large number of participating groups and the wide range of geographical distribution indicated that group standards could play a positive role in the sustained and positive development of cosmetic industry. The future development of cosmetic industry was also prospected。
文摘The deteriorated continuous rigid frame bridge is strengthened by external prestressing. Static loading tests wereconducted before and after the bridge rehabilitation to verify the effectiveness of the rehabilitation process. Thestiffness of the repaired bridge is improved, and the maximum deflection of the load test is reduced from 37.9 to27.6 mm. A bridge health monitoring system is installed after the bridge is reinforced. To achieve an easy assessmentof the bridge’s safety status by directly using transferred data, a real-time safety warning system is createdbased on a five-level safety standard. The threshold for each safety level will be determined by theoretical calculationsand the outcomes of static loading tests. The highest risk threshold will be set at the ultimate limit statevalue. The remaining levels, namely middle risk, low risk, and very low risk, will be determined usingreduction coefficients of 0.95, 0.9, and 0.8, respectively.