OBJECTIVE: To investigate Traditional Chinese Medicine(TCM) constitutions of youths in colleges,and their physical and mental health conditions of different TCM constitutions, so as to provide a theoretical basis for ...OBJECTIVE: To investigate Traditional Chinese Medicine(TCM) constitutions of youths in colleges,and their physical and mental health conditions of different TCM constitutions, so as to provide a theoretical basis for the TCM way to improve young people's physical and mental health.METHODS: The Standard TCM Constitutions' Classification and Determination Questionnaire was used to measure the body health condition, and the Symptom Checklist 90 Questionnaire and the Questionnaire of the National Student Physical Health Standards were used to determine mental and physical health conditions respectively in 1421 young participants validly answering the questionnaires in Zhejiang Province.RESULTS: The participants had a mean age of 19.96years(SD = 0.95 years) with the majority of females(55.10%). One fourth of the 1421 participants were the Ping-he constitution and others were the tendency constitutions. Participants with Ping-he module(which has characteristics of moderate posture,rosy, energetic and is a healthy condition in TCM)were healthier than those with tendency constitutions in physical and mental health, with 65.81 ±7.83(men) and 77.99 ± 7.24(women) scores in the physical test and around 1.25 scores in the mental health test. College students with combined biased constitutions were more likely suffer force, sensitive, depression and anxiety.CONCLUSION: Most of college students have a tendency or biased constitution which could be more likely to suffer suboptimal health status and diseases. Youths in college themselves and health providers should pay more attention to their potential health issues and make proper healthcare plan according to their own TCM constitution.展开更多
OBJECTIVE:Yang-deficiency constitution(YADC)is a common unbalanced constitution that predisposes individuals to certain diseases.However,not all people with YADC manifest develop diseases.This calls for delineation of...OBJECTIVE:Yang-deficiency constitution(YADC)is a common unbalanced constitution that predisposes individuals to certain diseases.However,not all people with YADC manifest develop diseases.This calls for delineation of the underlying molecular mechanisms.Previous studies suggested that the gut microbiota and gene differential expression should be considered.METHODS:In the present study,we compared profiles of gut microbiota between four healthy YADC individuals and those of five healthy balanced constitution(BC)counterparts,based on 16 S r RNA gene sequence analysis.Furthermore,YADC relevant genes identified by comparing 62 healthy YADC and 58 healthy BC individuals in total to perform intersection analysis,functional clustering and pathway enrichment analyses.RESULTS:The levels of harmful gut microbiota(Prevotellaceae,LDA score>4.0,P=0.0141)and beneficial gut microbiota(Ruminococcaceae,LDA score>4.0,P=0.0025,Faecalibacterium,LDA score>4.0,P=0.0484)were both elevated in healthy YADC individuals.Also,we found that the specific metabolic pathway with 2,6-Dichloro-p-hydroquinone 1,2-Dioxygenase(Pcp A)as the core in gut microbiota and the glutathione transferase activity has been enriched by YADC relevant genes in healthy YADC individuals were both responsible for the detoxification of halogenated aromatic hydrocarbon substances.CONCLUSIONS:Both beneficial and harmful factors had been detected in healthy YADC individuals,functionally,they may have triggered homeostasis to maintain the health of individuals with YADC.The homeostasis may be maintained by beneficial and harmful factors from gut flora and genes.Future studies are expected to focus on halogenated aromatic hydrocarbons and their detoxification processes.展开更多
目的:分析我国中学生近30年体质健康标准达标优秀率趋势,为国家制定学生体质健康干预措施提供依据。方法:选取1985—2014年6次全国学生体质与健康调研中738523名13~18岁中学生,根据《全国学生体质与健康调研工作手册》分析身高、体质量...目的:分析我国中学生近30年体质健康标准达标优秀率趋势,为国家制定学生体质健康干预措施提供依据。方法:选取1985—2014年6次全国学生体质与健康调研中738523名13~18岁中学生,根据《全国学生体质与健康调研工作手册》分析身高、体质量、肺活量和身体素质指标。体质健康达标优秀依据《国家学生体质健康标准》(2014年修订)综合评分定义,≥90.0分为优秀。采用χ2检验比较不同性别、年龄、地区和年度学生体质健康达标优秀率的差异,绘制地图比较不同年度各省份体质健康达标优秀率的分布变化。结果:1985—2014年,中国汉族13~18岁学生平均身高、体质量、体重指数(body mass index,BMI)不断增长,而平均肺活量和身体素质指标波动较大。总体体质健康达标优秀率从1985年的2.7%上升到1995年的4.4%,然后持续下降至2005年的1.1%,2010年反弹了0.6个百分点,2014年继续提高,达到2.2%。近30年来,男生体质健康达标优秀率一直高于女生(P<0.001),13~15岁初中生优秀率始终高于16~18岁高中生(P<0.001),东部地区优秀率高于中部和西部地区(P<0.001)。1985年仅个别地区中学生体质健康达标优秀率<1%,2005年几乎一半省份(14/30)的达标优秀率<1%,2014年有所好转,东部沿海部分地区中学生体质健康达标优秀率较高,中部省份和西部省份偏低。结论:近30年来我国中学生体质健康达标优秀率呈波动趋势,距离健康中国2030规划纲要的目标差距较大,各地区需要积极采取措施促进学生体育锻炼,提高学生体质健康水平。展开更多
基金Supported by Research on Promoting College Students'Physical and Mental Health and Social Adaptability by Sports Curriculum from the Department of Education of Zhejiang Province(No.Y201016155)
文摘OBJECTIVE: To investigate Traditional Chinese Medicine(TCM) constitutions of youths in colleges,and their physical and mental health conditions of different TCM constitutions, so as to provide a theoretical basis for the TCM way to improve young people's physical and mental health.METHODS: The Standard TCM Constitutions' Classification and Determination Questionnaire was used to measure the body health condition, and the Symptom Checklist 90 Questionnaire and the Questionnaire of the National Student Physical Health Standards were used to determine mental and physical health conditions respectively in 1421 young participants validly answering the questionnaires in Zhejiang Province.RESULTS: The participants had a mean age of 19.96years(SD = 0.95 years) with the majority of females(55.10%). One fourth of the 1421 participants were the Ping-he constitution and others were the tendency constitutions. Participants with Ping-he module(which has characteristics of moderate posture,rosy, energetic and is a healthy condition in TCM)were healthier than those with tendency constitutions in physical and mental health, with 65.81 ±7.83(men) and 77.99 ± 7.24(women) scores in the physical test and around 1.25 scores in the mental health test. College students with combined biased constitutions were more likely suffer force, sensitive, depression and anxiety.CONCLUSION: Most of college students have a tendency or biased constitution which could be more likely to suffer suboptimal health status and diseases. Youths in college themselves and health providers should pay more attention to their potential health issues and make proper healthcare plan according to their own TCM constitution.
基金Supported by the Applied Basic Research Foundation of Yunnan Province(202101AY070001-050,2019FE001(-026))the Open Foundation(2019KF003)of State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan,Yunnan University+1 种基金the National Natural Science Foundation of China(81860255,81760869)the Scientific Research Foundation of Yunnan Provincial Department of Education(2018JS159)。
文摘OBJECTIVE:Yang-deficiency constitution(YADC)is a common unbalanced constitution that predisposes individuals to certain diseases.However,not all people with YADC manifest develop diseases.This calls for delineation of the underlying molecular mechanisms.Previous studies suggested that the gut microbiota and gene differential expression should be considered.METHODS:In the present study,we compared profiles of gut microbiota between four healthy YADC individuals and those of five healthy balanced constitution(BC)counterparts,based on 16 S r RNA gene sequence analysis.Furthermore,YADC relevant genes identified by comparing 62 healthy YADC and 58 healthy BC individuals in total to perform intersection analysis,functional clustering and pathway enrichment analyses.RESULTS:The levels of harmful gut microbiota(Prevotellaceae,LDA score>4.0,P=0.0141)and beneficial gut microbiota(Ruminococcaceae,LDA score>4.0,P=0.0025,Faecalibacterium,LDA score>4.0,P=0.0484)were both elevated in healthy YADC individuals.Also,we found that the specific metabolic pathway with 2,6-Dichloro-p-hydroquinone 1,2-Dioxygenase(Pcp A)as the core in gut microbiota and the glutathione transferase activity has been enriched by YADC relevant genes in healthy YADC individuals were both responsible for the detoxification of halogenated aromatic hydrocarbon substances.CONCLUSIONS:Both beneficial and harmful factors had been detected in healthy YADC individuals,functionally,they may have triggered homeostasis to maintain the health of individuals with YADC.The homeostasis may be maintained by beneficial and harmful factors from gut flora and genes.Future studies are expected to focus on halogenated aromatic hydrocarbons and their detoxification processes.
文摘目的:分析我国中学生近30年体质健康标准达标优秀率趋势,为国家制定学生体质健康干预措施提供依据。方法:选取1985—2014年6次全国学生体质与健康调研中738523名13~18岁中学生,根据《全国学生体质与健康调研工作手册》分析身高、体质量、肺活量和身体素质指标。体质健康达标优秀依据《国家学生体质健康标准》(2014年修订)综合评分定义,≥90.0分为优秀。采用χ2检验比较不同性别、年龄、地区和年度学生体质健康达标优秀率的差异,绘制地图比较不同年度各省份体质健康达标优秀率的分布变化。结果:1985—2014年,中国汉族13~18岁学生平均身高、体质量、体重指数(body mass index,BMI)不断增长,而平均肺活量和身体素质指标波动较大。总体体质健康达标优秀率从1985年的2.7%上升到1995年的4.4%,然后持续下降至2005年的1.1%,2010年反弹了0.6个百分点,2014年继续提高,达到2.2%。近30年来,男生体质健康达标优秀率一直高于女生(P<0.001),13~15岁初中生优秀率始终高于16~18岁高中生(P<0.001),东部地区优秀率高于中部和西部地区(P<0.001)。1985年仅个别地区中学生体质健康达标优秀率<1%,2005年几乎一半省份(14/30)的达标优秀率<1%,2014年有所好转,东部沿海部分地区中学生体质健康达标优秀率较高,中部省份和西部省份偏低。结论:近30年来我国中学生体质健康达标优秀率呈波动趋势,距离健康中国2030规划纲要的目标差距较大,各地区需要积极采取措施促进学生体育锻炼,提高学生体质健康水平。
