Empirical Analysis of the Relationship between Price-Earnings Ratio and the Development of the Capital Markets

On the one hand,the P/E ratio measures growth opportunity,bubble level,and investment value of a company.On the other hand,the calculation of P/E is rather simple and convenient,and therefore considerably popular.This article selects the monthly data for five years from 2012 to 2017,of all Shanghai A shares to conduct an empirical analysis.Based on the Gordon model,macroeconomic variables,time variable,technical indicators,and other variables are introduced to reflect the actual price-earnings ratio.This article innovatively introduces the OBV energy wave indicator in empirical research to measure the influence of market heat and investor sentiment on the price-earnings ratio.This paper regresses both on the whole data and on the data grouped according to the average earnings per share,and concludes that P/E estimated by Gordon model,company size,and time factor have a considerable degree of explanation for the actual price-earnings ratio,and the innovative introduction of OBV energy wave indicator also shows significant correlation and explanation.

Impact of International Financial Reporting Standards （IFRS） Adoption on Key Financial Ratios＂ The Case of the Czech Republic

This contribution analyzes the impact of new International Financial Reporting Standards （IFRS） reporting rules on financial ratios prepared in the Czech companies. Using a sample of 16 Czech firms, we attempt to measure the scope and size of the differences in the selected set of financial ratios as calculated with data reported according to the traditional Czech accounting standards （CAS） and under the IFRS provisions. Our study discovers that there are important differences resulting from the two reporting formats. Our research comes to a conclusion that translation of Czech statements to IFRS may cause changes in the values of financial indicators without relationship to the real change in the firms＇ value, performance, and stability. Even though the findings were not statistically significant, the indicative results of our measurements disclosed an important fact that the transition to IFRS could cause deterioration of key indicators and thereby could impact on the overall rating of companies. One needs to be cautious with generalization due to the small sample size.

Oils with different degree of saturation:effects on ileal digestibility of fat and corresponding additivity and bacterial community in growing pigs

Background Oils are important sources of energy in pig diets.The combination of oils with different degree of saturation contributes to improve the utilization efficiency of the mixed oils and may reduce the cost of oil supplemented.An experiment was conducted to evaluate the effects of oils with different degree of saturation on the fat digestibility and corresponding additivity and bacterial community in growing pigs.Methods Eighteen crossbred(Duroc×Landrace×Yorkshire)barrows(initial body weight:29.3±2.8 kg)were surgically fitted with a T-cannula in the distal ileum.The experimental diets included a fat-free basal diet and 5 oil-added diets.The 5 oil-added diets were formulated by adding 6%oil with different ratio of unsaturated to saturated fatty acids(U:S)to the basal diet.The 5 oils were palm oil(U:S=1.2),canola oil(U:S=12.0),and palm oil and canola oil were mixed in different proportions to prepare a combination of U:S of 2.5,3.5 and 4.5,respectively.Results The apparent and standardized ileal digestibility(AID and SID)of fat and fatty acids increased linearly(P<0.05)as the U:S of dietary oils increased except for SID of fat and C18:2.The AID and SID of fat and fatty acids differed among the dietary treatments(P<0.05)except for SID of unsaturated fatty acids(UFA)and C18:2.Fitted one-slope broken-line analyses for the SID of fat,saturated fatty acids(SFA)and UFA indicated that the breakpoint for U:S of oil was 4.14(R^(2)=0.89,P<0.01),2.91(R^(2)=0.98,P<0.01)and 3.84(R^(2)=0.85,P<0.01),respectively.The determined SID of fat,C18:1,C18:2 and UFA in the mixtures was not different from the calculated SID of fat,C18:1,C18:2 and UFA.However,the determined SID of C16:0,C18:0 and SFA in the mixtures were greater than the calculated SID values(P<0.05).The abundance of Romboutsia and Turicibacter in pigs fed diet containing palm oil was greater than that in rapeseed oil treatment group,and the two bacteria were negatively correlated with SID of C16:0,C18:0 and SFA(P<0.05).Conclusions The optimal U:S for improving the utilization efficiency of mixed oil was 4.14.The SID of fat and UFA for palm oil and canola oil were additive in growing pigs,whereas the SID of SFA in the mixture of two oils was greater than the sum of the values of pure oils.Differences in fat digestibility caused by oils differing in degree of saturation has a significant impact on bacterial community in the foregut.

Comparison of isolated-check visual evoked potential and standard automated perimetry in early glaucoma and high-risk ocular hypertension

AIM：To compare the diagnostic performance of isolatedcheck visual evoked potential（ic VEP） and standard automated perimetry（SAP）,for evaluating the application values of ic VEP in the detection of early glaucoma.METHODS：Totally 144 subjects（288 eyes） were enrolled in this study.ic VEP testing was performed with the Neucodia visual electrophysiological diagnostic system.A 15% positive-contrast（bright） condition pattern was used in this device to differentiate between glaucoma patients and healthy control subjects.Signal-to-noise ratios（SNR） were derived based on a multivariate statistic.The eyes were judged as abnormal if the test yielded an SNR≤1.SAP testing was performed with the Humphrey Field Analyzer II.The visual fields were deemed as abnormality if the glaucoma hemifield test results outside normal limits;or the pattern standard deviation with P〈0.05;or the cluster of three or more non-edge points on the pattern deviation plot in a single hemifield with P〈0.05,one of which must have a P〈0.01.Disc photographs were graded as either glaucomatous optic neuropathy or normal by two experts who were masked to all other patient information.Moorfields regression analysis（MRA） used as a separate diagnostic classification was performed by Heidelberg retina tomograph（HRT）.RESULTS：When the disc photograph grader was used as diagnostic standard,the sensitivity for SAP and ic VEP was 32.3% and 38.5% respectively and specificity was 82.3% and 77.8% respectively.When the MRA Classifier was used as the diagnostic standard,the sensitivity for SAP and ic VEP was 48.6% and 51.4% respectively and specificity was 84.1% and 78.0% respectively.When the combined structural assessment was used as the diagnostic standard,the sensitivity for SAP and ic VEP was 59.2%and 53.1% respectively and specificity was 84.2% and 84.6% respectivlely.There was no statistical significance between the sensitivity or specificity of SAP and ic VEP,regardless of which diagnostic standard was based on.CONCLUSION：The diagnostic performance of ic VEP is not better than that of SAP in the detection of early glaucoma.

Numerical investigation on the caving mechanism with different standard deviations of top coal block size in LTCC

The size distribution of the broken top coal blocks is an important factor,affecting the recovery ratio and the efficiency of drawing top coal in longwall top coal caving(LTCC)mining panel.The standard deviation of top coal block size(dt)is one of the main parameters to reflect the size distribution of top coal.To find the effect of dt on the caving mechanism,this study simulates experiments with 9 different dt by using discrete element software PFC.The dt is divided into two stages:uniform distribution stage(UDS)whose dt is less than 0.1(Schemes 1–5),and nonuniform distribution stage(NDS)whose dt is more than 0.1(Schemes 6–9).This research mainly investigates the variation of recovery ratio,drawing body shape,boundary of top coal,and contact force between particles in the two stages,respectively.The results showed that with the increasing dt,the recovery ratio of the panel increases first and then decreases in UDS.It is the largest in Scheme 3,which mainly increases the drawing volume at the side of starting drawing end.However,the recovery ratio decreases first and then increases quickly in NDS,and it is the largest in Scheme 9,where the drawing volume at the side of finishing drawing end are relatively higher.In UDS,the major size of top coal is basically medium,while in NDS,the size varies from medium to small,and then to large,with a distinct difference in shape and volume of the drawing body.When the major size of top coal is medium and small,the cross-section width of the initial boundary of top coal at each height is relatively small.Conversely,when the top coal size is large,the initial boundary of top coal has a larger opening range,the rotating angle of lower boundary is relatively small in the normal drawing stage,which is conducive to the development of drawing body and reduces the residual top coal,and the maximum particle velocity and the particles movement angle are both larger.This study lays a foundation for the prediction of recovery ratio,and suggests that the uniform top coal is more manageable and has a larger recovery ratio.

Comparative Analysis of Variations in Human Sex Ratios of Live Births Among African Populations and at Global Levels

Definition： The final net live birth delivery from the mother＇s womb, with distinct male and female genetic traits, forms a ratioof male live births per 100 female live births, termed as Sex Ratio at Birth （SRB）. Study areas and source of data： The studyareas are Africa and major worldwide continents and countries. The basic data are compiled from the National Populationand Housing Censuses, Demographic Sample Surveys, Demographic and Health Surveys, and Vital Registration Systems.Analytical approaches： The factors influencing the variations in SRB are identified by reviewing various documents, analysisof variance （ANOVA） techniques, and statistical measures of central tendency and dispersion. Results： The ratios areconsistently higher for advanced countries than the developing countries, with highest for China and India. The ANOVAresults show slight differences among the S0 African countries but show differences among the African regional states,whereas the standard deviation of the SRB among the advanced countries, including some Asian and Latin Americancountries shows non-significant variations. In conclusion, the mean SRB for African populations is 103 as against 106 forother countries.

基于多源数据的长江流域1982—2022年骤旱事件时空演变

骤发性干旱(简称骤旱)是一种突发性高且强度大的极端干旱现象,会对农业生产和生态系统构成严重威胁。近年来,长江流域骤旱频发,然而其骤旱时空演变格局及规律尚不明晰。本研究基于GLEAM、GLDAS和ERA5-Land数据,以标准化蒸发胁迫比及其变化值作为识别指标,开展1982—2022年长江流域骤旱识别,全面分析长江流域骤旱空间分布和时间演变特征;并鉴于2022年旱情的严重性和特殊性,重点分析该年长江流域骤旱事件。研究结果表明:①在空间分布上,长江流域上游的金沙江水系和中下游的大型水库湖泊骤旱发生频率最高且强度最大;②在时间演变上,骤旱发生频率、平均持续时间和强度均在长江流域整体上呈现出非显著上升趋势,而有显著变化趋势的区域在2001年前后表现出明显的趋势反转现象;③2022年夏季受极端高温热浪影响,长江流域遭遇大规模骤旱事件,具有波及范围广、持续时间长的特点,且骤旱在空间上呈现出从上游向下游传递的态势。

2022年全球及中国肺癌流行状况分析

目的根据国际癌症研究机构发布的2022年全球癌症统计报告,结合性别、年龄、人类发展指数(HDI)等特征分析2022年全球及中国肺癌发病和死亡情况。方法全球185个国家和地区的肺癌数据来源于GLOBOCAN 2022数据库,HDI根据联合国开发计划署公布的《2021年人类发展报告》数据进行整理。将癌症数据进行年龄、性别、HDI分层,描述全球及中国肺癌流行情况。采用Pearson相关分析评估年龄标化发病率(ASIR)、年龄标化死亡率(ASMR)及死亡发病比(M/I)与HDI之间的相关性。结果2022年全球肺癌总发病人数为248.1万,位列各癌种发病人数的第1位,ASIR(23.6/10万)位列各癌种的第3位;全球肺癌总死亡人数为181.7万,位列各癌种死亡人数的第1位,ASMR(16.8/10万)位列各癌种的第1位。2022年中国肺癌总发病人数为106.1万,占全球肺癌发病人数的42.8%,位列中国各癌种的第1位,ASIR(40.8/10万)位列中国各癌种的第1位;中国肺癌总死亡人数为73.3万,占全球肺癌死亡人数的40.4%,位列中国各癌种的第1位,ASMR(26.7/10万)位列中国各癌种的第1位。全球及中国男性肺癌发病人数、ASIR、死亡人数、ASMR均高于女性。全球及中国肺癌发病人数、ASIR、死亡人数、ASMR随年龄增长呈现上升趋势,40~44岁年龄组之后增长迅速。各个国家和地区ASIR、ASMR与HDI呈正相关(r=0.7393、0.6865,均P<0.0001),M/I与HDI呈负相关(r=-0.6881,P<0.0001)。结论全球及中国肺癌疾病负担严重,流行情况在不同HDI水平的国家和地区、性别、年龄别之间存在差异。

心房颤动患者华法林抗凝治疗初期发生抗凝过度的影响因素研究

背景心房颤动发病率高,是引起脑卒中、心血管疾病及全因死亡的重要危险因素,而适当的抗凝治疗是预防心房颤动相关性卒中的核心。华法林仍然是目前主要的抗凝药物,但其治疗窗较窄,固定剂量的华法林在治疗初期很容易导致过度或抗凝治疗不足,既往华法林抗凝过度的临床研究较少。目的分析心房颤动患者华法林抗凝治疗初期发生抗凝过度的流行病学和临床特征,并探讨发生抗凝过度的影响因素。方法该研究为单中心回顾性队列研究。纳入2017年1月—2022年12月临沂市人民医院收治的行华法林2.5 mg/d治疗的心房颤动患者552例为研究对象,收集患者临床资料,包括年龄、性别、体质量、心房颤动类型(非瓣膜型/瓣膜型)、合并疾病(高血压、糖尿病、低蛋白血症、转氨酶异常、心力衰竭)、联合用药情况(联合用药数量、联用抗菌药物、联用胺碘酮),收集患者治疗前实验室检查结果,包括血清白蛋白(Alb)、血清肌酐(Scr)、血清丙氨酸氨基转移酶(ALT)及血清天门冬氨酸氨基转移酶(AST)水平,收集患者治疗前国际标准化比值(INR)和用药7 d后INR。根据华法林治疗7 d后INR是否>3.0将患者分为抗凝过度组(INR>3.0,n=122)和未抗凝过度组(INR≤3.0,n=430),比较两组患者资料,并采用单因素及多因素Logistic回归分析探究华法林抗凝治疗初期发生抗凝过度的影响因素。结果抗凝过度组患者年龄,女性、瓣膜型心房颤动、低蛋白血症、转氨酶异常比例,联合用药数量,联用胺碘酮比例,AST高于未抗凝过度组;体质量、高血压比例、糖尿病比例、Alb、ALT低于未抗凝过度组(P<0.05)。多因素Logistic回归分析结果显示,年龄≥65岁(OR=1.954,95%CI=1.243~3.073,P=0.004)、体质量≤63 kg(OR=2.967,95%CI=1.841~4.783,P<0.001)、联合用药数量>5种(OR=1.976,95%CI=1.175~3.323,P=0.010)、Scr≥91μmol/L(OR=2.087,95%CI=1.222~3.561,P=0.007)是心房颤动患者华法林抗凝治疗初期发生抗凝过度的独立危险因素,而糖尿病(OR=0.424,95%CI=0.191~0.939,P=0.034)是心房颤动患者华法林抗凝治疗初期发生抗凝过度的保护因素。结论年龄≥65岁、体质量≤63 kg、联合用药数量>5种、Scr≥91μmol/L可能是心房颤动患者华法林抗凝治疗初期发生抗凝过度的危险因素,而糖尿病可能是心房颤动患者华法林抗凝治疗初期发生抗凝过度的保护因素。对于高龄、低体质量、多种药物联合使用、Scr水平升高的华法林抗凝治疗患者应密切监测INR水平。

嘉陵江流域骤发干旱时空演变特征分析

为探究嘉陵江流域骤发干旱可识别特性与时空演变特征,基于标准化蒸发胁迫比研究了1980—2020年嘉陵江流域骤发干旱的时空分布特征,通过密度聚类算法提取骤发干旱斑块分析了斑块质心的轨迹变化,并探讨了骤发干旱暴发初期气象要素的异常情况。结果表明:流域西北部骤发干旱强度更高且发展速度更快,流域南部骤发干旱持续时间更长;流域骤发干旱事件主要发生在4—11月,且骤发干旱事件的质心主要沿东北和西北方向迁移;嘉陵江流域的骤发干旱主要由高温和降水共同主导。

基于多维场景划分的台区线损率异常研判及关联用户精准追踪方法

针对台区线损率异常辨识困难,关联用户难以精准追踪的问题,提出一种基于多维场景划分的台区线损率异常研判及关联用户精准追踪方法。首先,提出了一种基于改进完备集合经验的模态分解(improved complete EEMD with adaptive noise,ICEEMDAN)算法的数据预处理策略,通过分析台区历史线损率曲线的变化趋势,构建台区线损率粗放场景集,并在此基础上采用支持向量聚类算法进一步对场景集进行二次精细划分,实现对台区多维场景集的建立。其次,提出一种基于簇类个案数目的区间动态平移策略,用于确定不同场景下线损率标准库的区间范围,并采用区间重叠率策略对划分中的孤立区间进行合并,实现对台区线损率标准库的完备划分。最后,给出一种基于关联分析的线损异常追踪方法,通过灰色关联分析法确定线损异常强相关因素,并基于改进Adtributor算法定量分析各因素和台区用户间的内在关联度,提高对台区线损率异常用户的追踪精度。算例采用台区真实数据进行仿真分析,结果表明了所提方法的有效性和实用性。

幕墙中空玻璃内外片风荷载分配比例研究

中空玻璃在我国建筑幕墙中广泛使用,但关于中空玻璃内外片风荷载分配比例的研究不充分,规范相应规定有待进一步完善。首先归纳总结了中空玻璃分荷比例的影响要素,对比分析了中、欧相关规范的优劣异同。基于内外面板挠度位移场与理想气体方程所得的中空层气体体积变化量相同的原理,建立了适用于框支式和点支式的高精度中空玻璃承载力计算模型,并进行了中空玻璃内、外面板分荷比例的参数化分析,计算结果与欧盟规范结果吻合良好。最后,针对主流面板厚度的框支式中空玻璃,考虑中空层厚度、面板大小、长宽比等影响因素,通过最小二乘法曲面拟合得到了适用于不同情况的中空层系数计算公式。

活性炭-土-膨润土复合材料阻隔性能研究

以粉质粘土(SC)作为母土,通过柔性壁渗透试验和静平衡吸附试验分别研究了不同配比的土-膨润土(SB)及活性炭-土-膨润土(ASB)在不同渗滤液工况下的渗透性能及吸附性能。结果表明,将Pb(NO3)2溶液作为渗液,单元体渗透性能随Pb2+浓度增大而逐渐增强,且渗液浓度相同时SB渗透系数随膨润土掺量增加呈大幅降低后趋于平稳趋势。膨润土和活性炭的掺入可有效增强材料的吸附性能,随渗液浓度的增加,SC、SB及ASB对Pb2+的吸附容量变大,且ASB较SC及SB吸附容量差值逐渐变大。综合防渗及地下水质量标准提出了满足修复重金属污染场地阻隔材料的基准配比,研究结果可为重金属污染场地的修复与治理提供参考。

基于FAERS的盐皮质激素受体拮抗剂不良事件信号挖掘

目的 促进盐皮质激素受体拮抗剂(MRA)的临床安全使用。方法 提取美国食品和药物管理局不良事件报告系统(FAERS)2018年第1季度至2023年第1季度上报的3种MRA(螺内酯、依普利酮及非奈利酮)相关药品不良事件(ADE)报告,采用监管活动医学词典中的系统器官分类(SOC)和首选语(PT)进行归类,采用报告比值比(ROR)法与英国药品和保健品管理局(MHRA)综合标准法挖掘ADE信号并进行分析。结果 获得以3类药物为首要怀疑药物的ADE报告35 908份,其中螺内酯27 792份、依普利酮6 734份、非奈利酮1 382份。涉及患者5 930例,其中螺内酯4 455例、依普利酮1 052例、非奈利酮423例;男女比例相当(49.45%比50.55%),以> 65岁患者居多(49.07%)。ADE上报者主要为医师(35.48%)和消费者(24.74%),上报国家主要为美国(37.37%),使用口服剂型的患者最多(47.89%)。PT层级共产生ADE信号467个,其中螺内酯312个、依普利酮136个、非奈利酮19个,包括高钾血症、急性肾损伤、低钠血症、颈静脉压降低等。共涉及26个SOC,其中螺内酯26个、依普利酮20个、非奈利酮8个,包括代谢及营养类疾病、肾脏及泌尿系统疾病、心脏器官疾病、各类检查等。结论 MRA常见ADE信号及其累及系统器官与相应药品说明书基本一致,但要警惕药品说明书中未记载的ADE,如先天性延髓性肌萎缩、慢性心力衰竭、颈静脉压升高、肌痛等。

Measures of Variability for Qualitative Variables Using the R Software

Although there are many measures of variability for qualitative variables, they are little used in social research, nor are they included in statistical software. The aim of this article is to present six measures of variation for qualitative variables of simple calculation, as well as to facilitate their use by means of the R software. The measures considered are, on the one hand, Freemans variation ratio, Morals universal variation ratio, Kvalseths standard deviation from the mode, and Wilcoxs variation ratio which are most affected by proximity to a constant random variable, where the measures of variability for qualitative variables reach their minimum value of 0. On the other hand, the Gibbs-Poston index of qualitative variation and Shannons relative entropy are included, which are more affected by the proximity to a uniform distribution, where the measures of variability for qualitative variables reach their maximum value of 1. Point and interval estimation are addressed. Bootstrap by the percentile and bias-corrected and accelerated percentile methods are used to obtain confidence intervals. Two calculation situations are presented: with a sample mode and with two or more modes. The standard deviation from the mode among the six considered measures, and the universal variation ratio among the three variation ratios, are particularly recommended for use.

不同种衣剂配方对油菜生长的影响

本研究旨在提高油菜种子质量,实现种子标准化,并促进油菜增产。通过对油菜种子进行丸粒化包衣,探讨了不同药种比种衣剂包衣对油菜生长的影响。以甘蓝型油菜‘帆鸣1号’为试材,研究了不同药种比的丸粒化种衣剂NXY-1和瑞士悬浮种衣剂SLS包衣油菜种子对油菜苗期生长的影响。结果表明:在丸粒化种衣剂NXY-1中,最佳药种质量比为1:300,该配比的丸粒化种衣剂能促进种子出苗,冬前和盛花期干鲜重比最高,出苗后21 d氮磷含量,钾含量较对照相比最高,能有效提高叶绿素和赤霉素含量,效果均优于进口种衣剂SLS。

基于护士主导的集束化抗凝管理在华法林抗凝治疗房颤患者中的应用价值

目的:探讨基于护士主导的集束化抗凝管理模式对房颤患者华法林抗凝治疗国际标准化比值(International normalized ratio,INR)达标率及血液流变学水平的影响。方法:选取我科2021年3月至2022年9月期间112例房颤拟服用或正在服用华法林的患者作为研究对象,按随机数字法分为两组,常规组56例用药期间行常规护理指导,抗凝组56例给予护士主导的集束化抗凝管理模式,对两组患者进行为期3 m的干预,采集静脉血对比抗凝效果和血液流变学指标,通过调查问卷对比自我管理能力,统计并记录干预期间并发症发生率。结果:抗凝组INR达标率低于常规组,TTR值高于常规组(P<0.05);干预前,两组成年人健康自我管理能力测评量表(Adult health self-management ability assessment scale,AHSMSRS)各维度评分及总分对比无差异(P>0.05),干预3 m后,两组AHSMSRS各维度评分均升高,且抗凝组高于常规组(P<0.05);干预前,两组D-二聚体(D-Dimer,D-D)、全血黏度(Whole blood viscosity,NB)、纤维蛋白原(Fibrinogen,FIB)、纤维蛋白原降解物(Fibrinogen degradation product,FDP)水平对比无差异(P>0.05),干预3 m后,两组D-D、NB、FIB、FDP水平均降低,且抗凝组低于常规组(P<0.05);抗凝组抗凝并发症发生率低于常规组(P<0.05)。结论:基于护士主导的集束化抗凝管理模式应用于房颤患者华法林抗凝治疗有助于增强抗凝效果,改善血液流变学,增强自我管理能力,降低抗凝并发症发生率。

从虚-湿-热-瘀探讨NLR、标化SUA与早期糖尿病肾病的相关性

【目的】基于“虚-湿-热-瘀”病机探讨外周血中性粒细胞计数与淋巴细胞计数比值(NLR)、标化SUA[血尿酸与血肌酐比值(SUA/Scr)]与早期糖尿病肾病(early diabetic kidney disease,EDKD)中医证型的相关性,为EDKD患者中医精准化治疗提供客观化依据。【方法】回顾性分析197例EDKD患者(包括单纯气阴两虚证42例、气阴两虚兼湿证44例、气阴两虚兼热证53例、气阴两虚兼瘀证58例)的临床资料,对比不同中医证型EDKD患者脂代谢指标、肾功能指标、NLR、标化SUA的水平差异,探讨NLR、标化SUA与EDKD中医证型的相关性。【结果】(1)不同中医证型EDKD患者的性别、糖化血红蛋白(HbA1c)比较,差异均无统计学意义(P>0.05);年龄方面,气阴两虚兼瘀证组年龄大于气阴两虚证组(P<0.05);病程方面,气阴两虚兼瘀证组病程大于其余各组(P<0.01);体质量指数(BMI)方面,气阴两虚证组<气阴两虚兼瘀证组<气阴两虚兼热证组<气阴两虚兼湿证组(P<0.05)。(2)气阴两虚证组的总胆固醇(TC)水平低于气阴两虚兼湿证组和气阴两虚兼瘀证组(P<0.05),气阴两虚证组的甘油三酯(TG)水平低于气阴两虚兼瘀证组(P<0.05),气阴两虚兼热证组的血肌酐(Scr)水平高于气阴两虚证组和气阴两虚兼湿证组(P<0.05),气阴两虚证组的肾小球滤过率(eGFR)水平高于气阴两虚兼热证组和气阴两虚兼瘀证组(P<0.05),气阴两虚兼热证组的NLR水平高于其余3组(P<0.05),气阴两虚兼瘀证组的标化SUA水平低于气阴两虚兼湿证组和气阴两虚兼热证组(P<0.05)。(3)无序多分类Logistic回归分析结果显示,BMI、SUA是气阴两虚兼湿证的影响因素,BMI、SUA、NLR是气阴两虚兼热证的影响因素,BMI、TC、标化SUA是气阴两虚兼瘀证的影响因素,差异均有统计学意义(P<0.05或P<0.01)。【结论】NLR和标化SUA可作为EDKD中医证型的参考指标,NLR水平升高可能会加速气阴两虚兼热证的发生,标化SUA水平降低可能会加速气阴两虚兼瘀证的发生。

基于某中心支撑钢框架的中美标准对比研究

通过建立某典型中心支撑钢框架结构,考虑中美标准在材料及荷载等方面差异,以构件验算比为指标,梳理两种设计标准在该钢框架算例中的区别。结果表明,美标A36等级钢材屈服强度略高于国标Q235等级钢材;中美标准中地震作用参数取值在抗震设防目标理念上存在较大差异;风荷载区别主要在于基本风速测定时距和重现期不同;在风险等级基本一致的情况下,同一结构在国标下的构件验算比较低。

钢结构受扭构件设计方法研究与探讨

由于我国的《钢结构设计标准》(GB 50017—2017)对受扭构件的具体设计与计算方法没有详细介绍。为了对构件扭转的受力情况有更准确的把握及更合理的设计,详细介绍了美国钢结构标准ANSI/AISC 360-16的H3.1节受扭杆件设计方法,对该标准中的扭转强度设计值Tc的计算公式进行剖析,推导并验证了扭转强度设计值Tc所对应的构件的应力分布与应力比;探究了翼缘与腹板的宽厚比、截面高宽比对构件的扭转强度设计值Tc的影响;提出了扭转强度设计值Tc计算公式适用的截面尺寸范围建议。结果表明,在纯扭状态下构件截面厚度一致时,可以充分发挥材料性能,设计较为经济,为实际工程中钢结构受扭构件的设计与计算提供理论参照。