Objective This study aimed to compare the performance of standard-definition white-light endoscopy(SD-WL),high-definition white-light endoscopy(HD-WL),and high-definition narrow-band imaging(HD-NBI)in detecting colore...Objective This study aimed to compare the performance of standard-definition white-light endoscopy(SD-WL),high-definition white-light endoscopy(HD-WL),and high-definition narrow-band imaging(HD-NBI)in detecting colorectal lesions in the Chinese population.Methods This was a multicenter,single-blind,randomized,controlled trial with a non-inferiority design.Patients undergoing endoscopy for physical examination,screening,and surveillance were enrolled from July 2017 to December 2020.The primary outcome measure was the adenoma detection rate(ADR),defined as the proportion of patients with at least one adenoma detected.The associated factors for detecting adenomas were assessed using univariate and multivariate logistic regression.Results Out of 653 eligible patients enrolled,data from 596 patients were analyzed.The ADRs were 34.5%in the SD-WL group,33.5%in the HD-WL group,and 37.5%in the HD-NBI group(P=0.72).The advanced neoplasm detection rates(ANDRs)in the three arms were 17.1%,15.5%,and 10.4%(P=0.17).No significant differences were found between the SD group and HD group regarding ADR or ANDR(ADR:34.5%vs.35.6%,P=0.79;ANDR:17.1%vs.13.0%,P=0.16,respectively).Similar results were observed between the HD-WL group and HD-NBI group(ADR:33.5%vs.37.7%,P=0.45;ANDR:15.5%vs.10.4%,P=0.18,respectively).In the univariate and multivariate logistic regression analyses,neither HD-WL nor HD-NBI led to a significant difference in overall adenoma detection compared to SD-WL(HD-WL:OR 0.91,P=0.69;HD-NBI:OR 1.15,P=0.80).Conclusion HD-NBI and HD-WL are comparable to SD-WL for overall adenoma detection among Chinese outpatients.It can be concluded that HD-NBI or HD-WL is not superior to SD-WL,but more effective instruction may be needed to guide the selection of different endoscopic methods in the future.Our study’s conclusions may aid in the efficient allocation and utilization of limited colonoscopy resources,especially advanced imaging technologies.展开更多
在电源供电系统中,浪涌的产生会对电子元器件造成不可逆的损害。电源开断瞬息产生的强力尖峰脉冲会对集成电路进行浪涌冲击。本文就浪涌电压冲击对电路造成的损害,通过理论和实验分析了TVS实际选型问题,并对比分析了TVS电路和电容电路...在电源供电系统中,浪涌的产生会对电子元器件造成不可逆的损害。电源开断瞬息产生的强力尖峰脉冲会对集成电路进行浪涌冲击。本文就浪涌电压冲击对电路造成的损害,通过理论和实验分析了TVS实际选型问题,并对比分析了TVS电路和电容电路对浪涌冲击带来的失效问题的抑制能力,在此基础上提出了基于TVS和电容的浪涌保护电路方案。In the power supply system, the generation of surge will cause irreversible damage to electronic components. The strong spike pulse produced by the instant of power supply disconnection will cause surge impact to the integrated circuit. In this paper, based on the damage caused by surge voltage shock to the circuit, the actual TVS selection problem is analyzed through theory and experiment, and the suppression ability of TVS and capacitor circuit to the failure problem caused by surge shock is compared and analyzed. On this basis, the surge protection circuit scheme based on TVS and capacitor is proposed.展开更多
基金supported by the Beijing Municipal Science and Technology Commission(BMSTC,No.D171100002617001).
文摘Objective This study aimed to compare the performance of standard-definition white-light endoscopy(SD-WL),high-definition white-light endoscopy(HD-WL),and high-definition narrow-band imaging(HD-NBI)in detecting colorectal lesions in the Chinese population.Methods This was a multicenter,single-blind,randomized,controlled trial with a non-inferiority design.Patients undergoing endoscopy for physical examination,screening,and surveillance were enrolled from July 2017 to December 2020.The primary outcome measure was the adenoma detection rate(ADR),defined as the proportion of patients with at least one adenoma detected.The associated factors for detecting adenomas were assessed using univariate and multivariate logistic regression.Results Out of 653 eligible patients enrolled,data from 596 patients were analyzed.The ADRs were 34.5%in the SD-WL group,33.5%in the HD-WL group,and 37.5%in the HD-NBI group(P=0.72).The advanced neoplasm detection rates(ANDRs)in the three arms were 17.1%,15.5%,and 10.4%(P=0.17).No significant differences were found between the SD group and HD group regarding ADR or ANDR(ADR:34.5%vs.35.6%,P=0.79;ANDR:17.1%vs.13.0%,P=0.16,respectively).Similar results were observed between the HD-WL group and HD-NBI group(ADR:33.5%vs.37.7%,P=0.45;ANDR:15.5%vs.10.4%,P=0.18,respectively).In the univariate and multivariate logistic regression analyses,neither HD-WL nor HD-NBI led to a significant difference in overall adenoma detection compared to SD-WL(HD-WL:OR 0.91,P=0.69;HD-NBI:OR 1.15,P=0.80).Conclusion HD-NBI and HD-WL are comparable to SD-WL for overall adenoma detection among Chinese outpatients.It can be concluded that HD-NBI or HD-WL is not superior to SD-WL,but more effective instruction may be needed to guide the selection of different endoscopic methods in the future.Our study’s conclusions may aid in the efficient allocation and utilization of limited colonoscopy resources,especially advanced imaging technologies.
文摘在电源供电系统中,浪涌的产生会对电子元器件造成不可逆的损害。电源开断瞬息产生的强力尖峰脉冲会对集成电路进行浪涌冲击。本文就浪涌电压冲击对电路造成的损害,通过理论和实验分析了TVS实际选型问题,并对比分析了TVS电路和电容电路对浪涌冲击带来的失效问题的抑制能力,在此基础上提出了基于TVS和电容的浪涌保护电路方案。In the power supply system, the generation of surge will cause irreversible damage to electronic components. The strong spike pulse produced by the instant of power supply disconnection will cause surge impact to the integrated circuit. In this paper, based on the damage caused by surge voltage shock to the circuit, the actual TVS selection problem is analyzed through theory and experiment, and the suppression ability of TVS and capacitor circuit to the failure problem caused by surge shock is compared and analyzed. On this basis, the surge protection circuit scheme based on TVS and capacitor is proposed.