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Research on Switched Reluctance Motor for Automobile Starter/Generator System
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作者 全力 刘强 +1 位作者 赵德安 刘迪吉 《Defence Technology(防务技术)》 SCIE EI CAS 2006年第2期81-86,共6页
A self-designed and developed 12/10 switched reluctance motor(SRM)is chosen as the object of study and a prototype of 2.5?kW switched reluctance starter/generator with fly-wheel is designed based on the requirements o... A self-designed and developed 12/10 switched reluctance motor(SRM)is chosen as the object of study and a prototype of 2.5?kW switched reluctance starter/generator with fly-wheel is designed based on the requirements of the selected engine (Changan Aotooc three-cylinder engine wagon) for the starter, generator and drive. The 36?V/42 V DC source system is applied to establishing the simulation-analyzing model of the motor. A finite-element (FE) analysis of its two-dimensional electromagnetic field is conducted to obtain the exact model of the motor. Systematic simulation is carried out combining with its power conversion circuit and control element. Meanwhile the starting process and performance of the system are studied and analyzed with special efforts. Satisfactory result is derived from the testing of the prototype: theoretical analysis is basically matched with the tested data, which proves the rationality and feasibility of the design procedures, systematic modeling and control strategies. Therefore, the new 12/10-structure scheme is put forward based on the development and analysis of various SRM and it meets the requirements of the researched motor in terms of the structural parameters. 展开更多
关键词 汽车 开关转换装置 起动器 发电机 模拟试验
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A Novel Open-winding Permanent Magnetic Starter-generator 被引量:13
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作者 魏佳丹 周波 +3 位作者 韩楚 邓清唐 史明明 刘颖 《中国电机工程学报》 EI CSCD 北大核心 2011年第36期I0008-I0008,243,共1页
针对永磁电机应用于车载起动/发电系统时存在的电压调节困难、适用转速范围窄、功率因数较低等问题,提出一种新型永磁车载起动/发电系统。通过引入绕组开路型永磁电机,绕组一端接整流桥形成输出直流侧,另一端接逆变桥形成控制端,... 针对永磁电机应用于车载起动/发电系统时存在的电压调节困难、适用转速范围窄、功率因数较低等问题,提出一种新型永磁车载起动/发电系统。通过引入绕组开路型永磁电机,绕组一端接整流桥形成输出直流侧,另一端接逆变桥形成控制端,构成具有宽转速范围和高效率的永磁电机起动/发电系统。分析该系统的起动、发电一体化工作原理,给出了通过逆变侧变换器实现发电机电压、电流控制的方案。仿真和实验结果表明,该新型车载起动/发电系统具有优良的发电调压控制性能,并且适应较宽的转速范围。 展开更多
关键词 永磁起动机 永磁发电机 开放式 绕组 起动发电机 电压调节 功率因数 生成模式
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Implementation and Study of a Novel Doubly Salient Structure Starter/Generator System 被引量:26
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作者 刘闯 周波 严仰光 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2002年第3期150-155,共6页
A new type of double salient starter/generator is presented, which can be used in aircraft Low Voltage Direct Current (LVDC), Variable Speed Constant Frequency (VSCF) and High Voltage Direct Current (HVDC) systems. Th... A new type of double salient starter/generator is presented, which can be used in aircraft Low Voltage Direct Current (LVDC), Variable Speed Constant Frequency (VSCF) and High Voltage Direct Current (HVDC) systems. The operational theory of the motor and generator is analyzed, and corresponding control strategies are given. An 18kW prototype has been implemented to verify the system performance. It is shown that the DSM S/G system possesses simple structure, high efficiency and flexible control. It is ap... 展开更多
关键词 double salient motor starter/generator fielding winding permanent magnetic
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Study on Matching a 300 MVA Motor Generator with an Ohmic Heating Power Supply in HL-2M 被引量:6
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作者 彭建飞 宣伟民 +3 位作者 王海兵 李华俊 王英翘 王树锦 《Plasma Science and Technology》 SCIE EI CAS CSCD 2013年第3期300-302,共3页
A new 300 MVA/1350 MJ motor generator (MG) will be built to feed all of the poloidal field power supplies (PFPS) and auxiliary heating power supplies of the HL-2M tokamak. The MG has a vertical-shaft salient pole ... A new 300 MVA/1350 MJ motor generator (MG) will be built to feed all of the poloidal field power supplies (PFPS) and auxiliary heating power supplies of the HL-2M tokamak. The MG has a vertical-shaft salient pole 6-phase synchronous generator and a coaxial 8500 kW induction motor. The Ohmic heating power supply (OHPS) consisting of 4-quadrant DC pulsed convertor is the one with the highest parameters among the PFPS. Therefore, the match between the generator and the OHPS is very important. The matching study with Matlab/Simulink is described in this paper. The simulation results show that the subtransient reactance of the generator is closely related to the inversion operation of the OHPS. By setting various subtransient reactance in the simulation generator model and considering the cost reduction, the optimized parameters are obtained as xd" = 0.405 p.u. at 100 Hz for the generator. The models built in the simulation can be used as an important tool for studying the dynamic characteristics and the control strategy of other HL-2M PFPSes. 展开更多
关键词 motor generator ohmic heating power supply load matching six-phase gen-erator subtransient reactance
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RESEARCH OF THE SWITCHED RELUCTANCE STARTER/GENERATOR SYSTEMS 被引量:2
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作者 李磊 朱学忠 曹志亮 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 1999年第4期222-226,共5页
This paper focuses on the simulation and test of the switched reluctance starter/generator systems. Through the emulational analysis of the initial starting torque, the optimal turn-on section of the power switches is... This paper focuses on the simulation and test of the switched reluctance starter/generator systems. Through the emulational analysis of the initial starting torque, the optimal turn-on section of the power switches is discovered. The fundamental theory of the generating operation is analyzed with the linearity model, and a new method is presented based on voltage pulse width modulation for the generating mode control. Through the steady-state and optimized emulation of the output power and system efficiency, the optimizational control approach for the generating mode over a wide speed range is introduced. At last, the test of the 3KW prototype system shows that the dynamic and static performance of this system is fine. 展开更多
关键词 Electric generators LINEARIZATION Mathematical models Optimal control systems Pulse width modulation Reluctance motors starterS
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A Novel Motor Fault Diagnosis Method Based on Generative Adversarial Learning with Distribution Fusion of Discrete Working Conditions
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作者 Qixin Lan Binqiang Chen Bin Yao 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第8期2017-2037,共21页
Many kinds of electrical equipment are used in civil and building engineering.The motor is one of the main power components of this electrical equipment,which can provide stable power output.During the long-term use o... Many kinds of electrical equipment are used in civil and building engineering.The motor is one of the main power components of this electrical equipment,which can provide stable power output.During the long-term use of motors,various motor faults may occur,which affects the normal use of electrical equipment and even causes accidents.It is significant to apply fault diagnosis for the motors at the construction site.Aiming at the problem that signal data of faulty motor lack diversity,this research designs a multi-layer perceptron Wasserstein generative adversarial network,which is used to enhance training data through distribution fusion.A discrete wavelet decomposition algorithm is employed to extract the low-frequency wavelet coefficients from the original motor current signals.These are used to train themulti-layer perceptron Wasserstein generative adversarial model.Then,the trainedmodel is applied to generate fake current wavelet coefficients with the fused distribution.A motor fault classification model consisting of a feature extractor and pattern recognizer is built based on perceptron.The data augmentation experiment shows that the fake dataset has a larger distribution than the real dataset.The classification model trained on a real dataset,fake dataset and combined dataset achieves 21.5%,87.2%,and 90.1%prediction accuracy on the unseen real data,respectively.The results indicate that the proposed data augmentation method can effectively generate fake data with the fused distribution.The motor fault classification model trained on a fake dataset has better generalization performance than that trained on a real dataset. 展开更多
关键词 motor fault diagnosis data augmentation wavelet decomposition generative adversarial network civil and building engineering
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Torque Distribution Strategy for Integrated Starter/ Generator Hybrid Bus Implemented by Fuzzy Algorithm 被引量:3
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作者 钟虎 敖国强 +3 位作者 王锋 马兹林 冒晓建 卓斌 《Journal of Shanghai Jiaotong university(Science)》 EI 2008年第3期323-329,共7页
A torque distribution strategy was designed by using fuzzy logic to realize the optimal control. The vehicle load zones were dynamically divided into several zones by several torque lines to indicate the drivers deman... A torque distribution strategy was designed by using fuzzy logic to realize the optimal control. The vehicle load zones were dynamically divided into several zones by several torque lines to indicate the drivers demand and the high or low efficient operating areas of the diesel engine. The fuzzy logic controller with trapezoid membership function and Mamdani rule reference mechanism was utilized. There are over 100 rules used in this fuzzy-based torque distribution strategy which are sorted into four rule-bases. The fuel economy and acceleration tests were designed to test and validate the integrated starter/generator (ISG) bus perfor-mance using fuzzy-based torque distribution strategy. The fuel economy is improved 7.7% compared with the rule-based strategy. Finally the road test results reveal that there is about 15% improvement of fuel economy. And the 0-50 km/h acceleration time is 9.5% shorter than the original bus. 展开更多
关键词 hybrid electric vehicle integrated starter/generator (ISG) torque distribution strategy fuzzy logic control
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Analysis and Design of Surface Permanent Magnet Synchronous Motor and Generator 被引量:7
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作者 Chengyuan He Thomas Wu 《CES Transactions on Electrical Machines and Systems》 CSCD 2019年第1期94-100,共7页
This paper presents an analytical method to design the high-efficiency surface permanent magnet synchronous motor(SPMSM)or generator(SPMSG).The air-gap and permanent magnet size can be approximately determined based o... This paper presents an analytical method to design the high-efficiency surface permanent magnet synchronous motor(SPMSM)or generator(SPMSG).The air-gap and permanent magnet size can be approximately determined based on our mathematics model,which is the most important part of SPMSM design.From our method,we can know that motor’s power out torque is related to the torque angle that we selected in our design and it affects the air-gap and permanent magnet size.If we choose a low torque angle,the motor or generator’s overload power handing capability will increase.The embrace value has a vital place in designing a motor or generator due to its effects on air gap flux density,cogging torque,efficiency and so on.In order to avoid the knee effect,the working point of the permanent magnet we selected in the design should be bigger than 0.5.The developed 36 slots,4 poles,surface mound permanent generator is proposed.The corresponding finite element analysis(FEA)model is built based on our design method.Structure optimization includes stator and rotor structure size,permanent magnet size,magnetic bridge and air gap length which are analyzed and simulated by ANSYS Maxwell 2D FEA.Thermal analysis is conducted,and the housing of the alternator is designed.The alternator prototype is fabricated and tested based on our design. 展开更多
关键词 initeelement analysis FABRICATION high-efficiency mathematic model surface permanent magnet synchronous motor or generator.
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Analysis of the Comprehensive Physical Field for a New Flywheel Energy Storage Motor/Generator on Ships 被引量:1
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作者 Yali Yu Yuanxi Wang +1 位作者 Guosheng Zhang Feng Sun 《Journal of Marine Science and Application》 2012年第1期134-142,共9页
A novel flywheel energy storage (FES) motor/generator (M/G) was proposed for marine systems. The purpose was to improve the power quality of a marine power system (MPS) and strengthen the energy recycle. Two str... A novel flywheel energy storage (FES) motor/generator (M/G) was proposed for marine systems. The purpose was to improve the power quality of a marine power system (MPS) and strengthen the energy recycle. Two structures including the magnetic or non-magnetic inner-rotor were contrasted in the magnetostatic field by using finite element analysis (FEA). By optimally designing the size parameters, the average speed of FEA results of was 17 200 r/m, and the current was controlled between 62 and 68 A in the transient field. The electrical machine electromagnetism design was further optimized by the FEA in the temperature field, to find the local overheating point under the normal operation condition and provide guidance for the cooling system. Finally, it can be concluded from the comprehensive physical field analysis that the novel redundant structure M/G can improve the efficiency of the M/G and maintain the stability of the MPS. 展开更多
关键词 marine power system flywheel energy storage Halbach array magnet structure comprehensivephysical field motor/generator finite element analysis
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Overview and Analysis of PM Starter/Generator for Aircraft Electrical Power Systems 被引量:3
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作者 Zhuoran Zhang Jian Huang +2 位作者 Yunyi Jiang Weiwei Geng Yanwu Xu 《CES Transactions on Electrical Machines and Systems》 2017年第2期117-131,共15页
More Electrical Aircraft(MEA)which replaces the hydraulic and pneumatic power by electrical power leads to reducing emissions and fuel consumption.The MEA concept has led to a growing use of the starter/generator(S/G)... More Electrical Aircraft(MEA)which replaces the hydraulic and pneumatic power by electrical power leads to reducing emissions and fuel consumption.The MEA concept has led to a growing use of the starter/generator(S/G)system.Permanent magnet(PM)machines have been gaining interests for aircraft S/G system application over the last few years.This is mainly due to the several advantages,including high power density,high efficiency and high speed ability.The shortcoming of the PM machines is the de-­excitation problem in case of a failure,which is a main issue for the aircraft application.However,by using a PM machine with high reactance or multiphase configuration,the fault-­tolerant ability can be improved.In terms of the aircraft S/G system,this paper is going to present a comprehensive analysis of PM machines.Firstly,the state-­of-­the-­art of PM starter/generator(PMS/G)is summarized and the basic structure of PMS/G system is analyzed.Next,key technologies of the PMS/G system are summarized and analyzed.Finally,a flux weakening fault protection strategy that is used to suppress the turn-­to-­turn short circuit(SC)current is studied,simulated and verified.With the breakthrough of key technologies based on the development of high temperature electromagnetic material and high temperature power electronics,the PMS/G will be a potential candidate for aircraft S/G system including the embedded power generation system. 展开更多
关键词 Fault tolerant flux weakening strategy high reactance machine more electrical aircraft MULTIPHASE permanent magnet machine starter/generator
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Dynamical Analysis of DC Shunt Motor Powered by PV Generator Using Perturbation and Observation as MPPT Technique
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作者 Tha’er Omar Sweidan 《Energy and Power Engineering》 2017年第1期55-69,共15页
This paper presents the perturbation and observation (P & O) algorithm as maximum power point tracking (MPPT) method for the dynamical analysis of DC shunt motor fed by photovoltaic generator at different solar ir... This paper presents the perturbation and observation (P & O) algorithm as maximum power point tracking (MPPT) method for the dynamical analysis of DC shunt motor fed by photovoltaic generator at different solar irradiance levels. At each solar intensity, the maximum power point of current/voltage (I/V) characteristic of the PV generator is achieved by perturbation and observation algorithm. The nonlinear behavior of (I/V) characteristics of the PV generator at various solar intensities and the magnetization curve of the ferromagnetic material of the DC shunt motor are described by high order polynomial mathematical expression. The dynamical analysis of the DC shunt motor fed by PV generator at different solar intensity has been carried out, also the dynamical analysis of DC shunt motor is investigated at a step change in solar intensity levels with fixed load at motor. 展开更多
关键词 DC SHUNT motor MPPT P & O PV generator DYNAMICAL Analysis
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Design and Initial Testing of An Integrated Switched Reluctance Starter/Generator System for Unmanned Aerial Vehicle 被引量:1
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作者 Erxin Zhao Shoujun Song +3 位作者 Zhen Ma Xueping Zhang Le Ning Yang Liu 《CES Transactions on Electrical Machines and Systems》 2018年第4期377-383,共7页
According to specific performance requirements,an integrated switched reluctance starter/generator system,which can start the engine and supply electrical energy to the loads,is designed and manufactured for the unman... According to specific performance requirements,an integrated switched reluctance starter/generator system,which can start the engine and supply electrical energy to the loads,is designed and manufactured for the unmanned aerial vehicle.Considering the required starting torque and speed range,the geometrical dimensions of the switched reluctance machine are calculated based on the output equation and further optimized with finite element analysis,and the flux-linkage,inductance and static torque characteristics are illustrated.To verify the performances of the designed system,detailed simulation with the model considering piston engine and experiment using the test bench are carried out. 展开更多
关键词 Integrated starter/generator system switched reluctance machine(SRM) unmanned aerial vehicle(UAV)
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Direct Torque Control of Induction Motor Load Generator
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作者 Hamid R. Tolue 《Journal of Electrical Engineering》 2017年第2期57-66,共10页
DTC (direct torque control) of induction motor drives has many outstanding performance and implementation properties. This paper presents an innovative direct torque controlled load generator based on space vector m... DTC (direct torque control) of induction motor drives has many outstanding performance and implementation properties. This paper presents an innovative direct torque controlled load generator based on space vector modulation suitable for the emerging applications such as electrical test benches that require extremely fast large-signal torque and dynamic responses. To realize system performance, two methods based on the classical DTC (with six-sector switch table) and the proposed twelve-sector DTC have been analyzed and used for modelling the dynamometer. The performance of the proposed dynamometer is investigated by simulating different parts of the system and results are presented for several industrial load profiles. Finally, limitations and advantages of each controller are presented and analyzed. 展开更多
关键词 DTC motor control induction motor load generator
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通过西门子Starter软件调试G120C变频器
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作者 曾其勇 《变频器世界》 2024年第9期99-103,共5页
文章介绍了使用西门子变频器调试工具Starter软件对G120C变频器进行调试的过程。其中包括恢复出厂设置、宏应用、软件控制、电机识别、PID压力调节等功能。
关键词 G120C starter 软件调试 配置向导 电机识别
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Xilinx FPGA system generator在伺服电机控制中的应用 被引量:3
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作者 程龙 王卫兵 +2 位作者 王挺峰 陈娟 郭劲 《电子测量技术》 2015年第10期68-71,86,共5页
为了避免编写FPGA语言HDL代码的烦琐性,借助于Simulink集成工具箱中Xilinx系列FPGA独有的System Generator模块,围绕3种伺服电机控制应用进行了仿真和实验研究。首先,根据3种伺服电机控制所需PWM信号波形,利用System Generator建立Simul... 为了避免编写FPGA语言HDL代码的烦琐性,借助于Simulink集成工具箱中Xilinx系列FPGA独有的System Generator模块,围绕3种伺服电机控制应用进行了仿真和实验研究。首先,根据3种伺服电机控制所需PWM信号波形,利用System Generator建立Simulink仿真框图;其次,在Simulink仿真结果正确的基础上生成HDL代码;然后,利用ISE的仿真配套软件ModelSim对HDL代码仿真测试;最后,在ModelSim仿真结果正确的基础上将代码载入FPGA硬件,并利用ChipScope Pro对PWM信号进行实验测试。实验结果与仿真结果的吻合,表明此方法简单易行,具有一定的实际应用价值。 展开更多
关键词 伺服电机 FPGA system generator SIMULINK PWM
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基于System Generator直流力矩电机模型及控制系统仿真 被引量:3
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作者 李宝荣 李先峰 +1 位作者 颜昌翔 于平 《仪表技术与传感器》 CSCD 北大核心 2013年第3期105-107,110,共4页
对有限转角直流无刷力矩电机及其控制系统进行研究,分析了电机模型和闭环PI控制模式模型的工作原理,着重讨论了电流环闭环PI控制模式对电机控制系统性能的影响。利用SG软件建立模型,通过仿真试验和实际测试,对比实际电流和仿真电流的上... 对有限转角直流无刷力矩电机及其控制系统进行研究,分析了电机模型和闭环PI控制模式模型的工作原理,着重讨论了电流环闭环PI控制模式对电机控制系统性能的影响。利用SG软件建立模型,通过仿真试验和实际测试,对比实际电流和仿真电流的上升时间、超调量和稳定电流等参数,验证了仿真模型的正确性,该仿真控制模型应用于实际系统中具有电流响应快速平稳、超调小、无静差等特点,为电机控制系统的设计提供一种新的思路。 展开更多
关键词 System generator 直流力矩电机 PI控制
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Research on Iron Loss of Switched Reluctance Starter/Generator for Energy Storage
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作者 Hao Chen Xing Wang +8 位作者 Yongqiang Liu Vuong Dang Quoc Wenju Yan Muhammad Saqib Antonino Musolino Guanjun Wang Yong Qi Ali Asghar Memon Alexandros G.Paspatis 《Protection and Control of Modern Power Systems》 SCIE EI 2024年第4期147-159,共13页
In order to better realize the energy recovery and storage of hybrid EVs(HEVs),a switched reluctance starter/generator(SRS/G)with both starting and power generation functions is investigated in this paper.First,the ir... In order to better realize the energy recovery and storage of hybrid EVs(HEVs),a switched reluctance starter/generator(SRS/G)with both starting and power generation functions is investigated in this paper.First,the iron loss of SRS/G is mainly studied to reduce the motor loss and improve the power generation efficiency.Then,the energy storage of hybrid EVs can be effectively improved.Secondly,a magnetic flux density(MFD)waveforms solution method is proposed to solve the difficulty in calculating the iron loss of the SRS/G.Compared with the commonly used finite element method,the proposed solution method has the advantages of simple,fast and small computational amount.Meanwhile,considering the different operating conditions of SRS/G,the iron loss models for both the time-domain and frequency-domain are established.In addition,the calculation formula of the variable coefficient Bertotti three-term loss separation is improved.As the hysteresis loss coefficient,the Steinmetz coefficient and the stray loss coefficient are respectively fitted by the Fourier fitting method.This method is also applied to solve the iron loss of SRS/G.Finally,through an experimental verification,it is indicated that the development of proposed method has high accuracy. 展开更多
关键词 Switched reluctance starter/generator energy storage iron loss finite element method magnetic flux density(MFD)
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The Onsager reciprocity relation and generalized efficiency of a thermal Brownian motor 被引量:4
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作者 高天附 张悦 陈金灿 《Chinese Physics B》 SCIE EI CAS CSCD 2009年第8期3279-3286,共8页
Based on a general model of Brownian motors, the Onsager coefficients and generalized efficiency of a thermal Brownian motor are calculated analytically. It is found that the Onsager reciprocity relation holds and the... Based on a general model of Brownian motors, the Onsager coefficients and generalized efficiency of a thermal Brownian motor are calculated analytically. It is found that the Onsager reciprocity relation holds and the Onsager coefficients are not affected by the kinetic energy change due to the particle's motion. Only when the heat leak in the system is negligible can the determinant of the Onsager matrix vanish. Moreover, the influence of the main parameters characterizing the model on the generalized efficiency of the Brownian motor is discussed in detail. The characteristic curves of the generalized efficiency varying with these parameters are presented, and the maximum generalized efficiency and the corresponding optimum parameters are determined. The results obtained here are of general significance. They are used to analyze the performance characteristics of the Brownian motors operating in the three interesting cases with zero heat leak, zero average drift velocity or a linear response relation, so that some important conclusions in current references are directly included in some limit cases of the present paper. 展开更多
关键词 Brownian motor Onsager coefficient generalized efficiency performance characteristic
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Performance Prediction of Switched Reluctance Motor using Improved Generalized Regression Neural Networks for Design Optimization 被引量:7
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作者 Zhu Zhang Shenghua Rao Xiaoping Zhang 《CES Transactions on Electrical Machines and Systems》 2018年第4期371-376,共6页
Since practical mathematical model for the design optimization of switched reluctance motor(SRM)is difficult to derive because of the strong nonlinearity,precise prediction of electromagnetic characteristics is of gre... Since practical mathematical model for the design optimization of switched reluctance motor(SRM)is difficult to derive because of the strong nonlinearity,precise prediction of electromagnetic characteristics is of great importance during the optimization procedure.In this paper,an improved generalized regression neural network(GRNN)optimized by fruit fly optimization algorithm(FOA)is proposed for the modeling of SRM that represent the relationship of torque ripple and efficiency with the optimization variables,stator pole arc,rotor pole arc and rotor yoke height.Finite element parametric analysis technology is used to obtain the sample data for GRNN training and verification.Comprehensive comparisons and analysis among back propagation neural network(BPNN),radial basis function neural network(RBFNN),extreme learning machine(ELM)and GRNN is made to test the effectiveness and superiority of FOA-GRNN. 展开更多
关键词 Fruit fly optimization algorithm generalized regression neural networks switched reluctance motor
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Chx10+V2a interneurons in spinal motor regulation and spinal cord injury 被引量:3
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作者 Wen-Yuan Li Ling-Xiao Deng +3 位作者 Feng-Guo Zhai Xiao-Yu Wang Zhi-Gang Li Ying Wang 《Neural Regeneration Research》 SCIE CAS CSCD 2023年第5期933-939,共7页
Chx10-expressing V2 a(Chx10+V2 a) spinal interneurons play a large role in the excitatory drive of motoneurons. Chemogenetic ablation studies have demonstrated the essential nature of Chx10+V2 a interneurons in the re... Chx10-expressing V2 a(Chx10+V2 a) spinal interneurons play a large role in the excitatory drive of motoneurons. Chemogenetic ablation studies have demonstrated the essential nature of Chx10+V2 a interneurons in the regulation of locomotor initiation, maintenance, alternation, speed, and rhythmicity. The role of Chx10+V2 a interneurons in locomotion and autonomic nervous system regulation is thought to be robust, but their precise role in spinal motor regulation and spinal cord injury have not been fully explored. The present paper reviews the origin, characteristics, and functional roles of Chx10+V2 a interneurons with an emphasis on their involvement in the pathogenesis of spinal cord injury. The diverse functional properties of these cells have only been substantiated by and are due in large part to their integration in a variety of diverse spinal circuits. Chx10+V2 a interneurons play an integral role in conferring locomotion, which integrates various corticospinal, mechanosensory, and interneuron pathways. Moreover, accumulating evidence suggests that Chx10+V2 a interneurons also play an important role in rhythmic patterning maintenance, leftright alternation of central pattern generation, and locomotor pattern generation in higher order mammals, likely conferring complex locomotion. Consequently, the latest research has focused on postinjury transplantation and noninvasive stimulation of Chx10+V2 a interneurons as a therapeutic strategy, particularly in spinal cord injury. Finally, we review the latest preclinical study advances in laboratory derivation and stimulation/transplantation of these cells as a strategy for the treatment of spinal cord injury. The evidence supports that the Chx10+V2 a interneurons act as a new therapeutic target for spinal cord injury. Future optimization strategies should focus on the viability, maturity, and functional integration of Chx10+V2 a interneurons transplanted in spinal cord injury foci. 展开更多
关键词 AXONS central nervous system central pattern generator Chx10 differentiation INTERNEURONS locomotion motor neurons PROPRIOSPINAL spinal cord injuries therapy transcription factor transplantation V2a neuron
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