Statistical analysis is critical in medical research.The objective of this article is to summarize the appropriate use and reporting of commonly used statistical methods in medical research,on the basis of existing st...Statistical analysis is critical in medical research.The objective of this article is to summarize the appropriate use and reporting of commonly used statistical methods in medical research,on the basis of existing statistical guidelines and the authors’experience in reviewing manuscripts,to provide recommendations for statistical applications and reporting.展开更多
These days when I look at scientific research papers or review manuscripts,there seems to be almost a competition to have a smaller p value as a means to present more significant findings.For example,a quick Internet ...These days when I look at scientific research papers or review manuscripts,there seems to be almost a competition to have a smaller p value as a means to present more significant findings.For example,a quick Internet search using＂p〈0.0000001＂turned up many papers even reporting their p values at this level.Can and should a smaller p value play such a role？In my opinion,it cannot.展开更多
Background：Robust statistical designing,sound statistical analysis,and standardized presentation are important to enhance the quality and transparency of biomedical research.This systematic review was conducted to su...Background：Robust statistical designing,sound statistical analysis,and standardized presentation are important to enhance the quality and transparency of biomedical research.This systematic review was conducted to summarize the statistical reporting requirements introduced by biomedical research journals with an impact factor of 10 or above so that researchers are able to give statistical issues＇ serious considerations not only at the stage of data analysis but also at the stage of methodological design.Methods：Detailed statistical instructions for authors were downloaded from the homepage of each of the included journals or obtained from the editors directly via email.Then,we described the types and numbers of statistical guidelines introduced by different press groups.Items of statistical reporting guideline as well as particular requirements were summarized in frequency,which were grouped into design,method of analysis,and presentation,respectively.Finally,updated statistical guidelines and particular requirements for improvement were summed up.Results：Totally,21 of 23 press groups introduced at least one statistical guideline.More than half of press groups can update their statistical instruction for authors gradually relative to issues of new statistical reporting guidelines.In addition,16 press groups,covering 44 journals,address particular statistical requirements.The most of the particular requirements focused on the performance of statistical analysis and transparency in statistical reporting,including ＂address issues relevant to research design,including participant flow diagram,eligibility criteria,and sample size estimation,＂ and ＂statistical methods and the reasons.＂ Conclusions：Statistical requirements for authors are becoming increasingly perfected.Statistical requirements for authors remind researchers that they should make sufficient consideration not only in regards to statistical methods during the research design,but also standardized statistical reporting,which would be beneficial in providing stronger evidence and making a greater critical appraisal of evidence more accessible.展开更多
文摘Statistical analysis is critical in medical research.The objective of this article is to summarize the appropriate use and reporting of commonly used statistical methods in medical research,on the basis of existing statistical guidelines and the authors’experience in reviewing manuscripts,to provide recommendations for statistical applications and reporting.
文摘These days when I look at scientific research papers or review manuscripts,there seems to be almost a competition to have a smaller p value as a means to present more significant findings.For example,a quick Internet search using＂p〈0.0000001＂turned up many papers even reporting their p values at this level.Can and should a smaller p value play such a role？In my opinion,it cannot.
基金This study was supported by the grant from the Beijing Natural Science Foundation （No. 7162061）. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
文摘Background：Robust statistical designing,sound statistical analysis,and standardized presentation are important to enhance the quality and transparency of biomedical research.This systematic review was conducted to summarize the statistical reporting requirements introduced by biomedical research journals with an impact factor of 10 or above so that researchers are able to give statistical issues＇ serious considerations not only at the stage of data analysis but also at the stage of methodological design.Methods：Detailed statistical instructions for authors were downloaded from the homepage of each of the included journals or obtained from the editors directly via email.Then,we described the types and numbers of statistical guidelines introduced by different press groups.Items of statistical reporting guideline as well as particular requirements were summarized in frequency,which were grouped into design,method of analysis,and presentation,respectively.Finally,updated statistical guidelines and particular requirements for improvement were summed up.Results：Totally,21 of 23 press groups introduced at least one statistical guideline.More than half of press groups can update their statistical instruction for authors gradually relative to issues of new statistical reporting guidelines.In addition,16 press groups,covering 44 journals,address particular statistical requirements.The most of the particular requirements focused on the performance of statistical analysis and transparency in statistical reporting,including ＂address issues relevant to research design,including participant flow diagram,eligibility criteria,and sample size estimation,＂ and ＂statistical methods and the reasons.＂ Conclusions：Statistical requirements for authors are becoming increasingly perfected.Statistical requirements for authors remind researchers that they should make sufficient consideration not only in regards to statistical methods during the research design,but also standardized statistical reporting,which would be beneficial in providing stronger evidence and making a greater critical appraisal of evidence more accessible.
