Optimizing care for gastric cancer with overt bleeding:Is systemic therapy a valid option?

Gastric cancer(GC)and gastroesophageal junction cancer(GEJC)represent a significant burden globally,with complications such as overt bleeding(OB)further exacerbating patient outcomes.A recent study by Yao et al evaluated the effectiveness and safety of systematic treatment in GC/GEJC patients presenting with OB.Using propensity score matching,the study balanced the comparison groups to investigate overall survival and treatment-related adverse events.The study's findings emphasize that systematic therapy can be safe and effective and contribute to the ongoing debate about the management of advanced GC/GEJC with OB,highlighting the complexities of treatment decisions in these high-risk patients.

贯彻STEAM教育理念传承乡土文化

随着全球化进程的加速,社会对人才质量和能力的需求日益提升,也对教育体系提出新的要求。本文从STEAM教育理念与乡土文化传承的融合点出发,根据二者在促进学生全面发展、培养创新思维能力与文化自信方面的共通之处,指出跨学科整合能促进文化多样性、实践性教学能增强文化体验性、创新思维能力培养能促进文化创新。本文就贯彻STEAM教育理念传承乡土文化问题,提出四个方面的传承路径:深入挖掘乡土资源,促进校本课程有效开发;融合乡土文化元素,整合跨学科课程;贯彻STEAM教育理念,提升教师专业素养;建立多方协作机制,促进乡土文化传承。

践行STEAM理念实现跨学科教学

随着教育理念的不断更新,跨学科教学逐渐成为重要趋势。STEAM教育理念作为一种融合了科学、技术、工程、艺术、数学的综合教育模式,对于培养学生的综合素质、创新能力具有重要意义。特别是在小学数学与科学的跨学科教学中,STEAM理念的应用能够更好地激发学生的学习兴趣,提高学生的学习效率和综合素质。基于此,本文阐述STEAM理念下小学数学与科学跨学科教学的重要性与有效策略,以期为基础教育改革提供参考。

将STEAM教育理念渗入科学教学

在幼儿园课程教学构成中,科学领域教学始终有着重要的地位。作为幼儿科学思维品质启迪的重要载体,科学教育能够有力促进幼儿核心素养得以良好发展。在STEAM教育理念的引导下,着眼于幼儿的科学素养、技术素养、工程素养、艺术素养和数学素养的综合性培养,将促进幼儿在学习活动中提升综合素养能力的过程变得充实、丰富和高效,为幼小衔接打好底色。

贯彻STEAM教育理念有效加强学生科学素养

随着科学技术的日新月异,科技教育被提到了重要位置。在各学段教育过程中,学生科学素养的培养和科技创新精神的引导越来越受到重视。小学阶段是小学生科学学习的基础时期,为提升小学生的科学素养,需要小学科学教师以STEAM教育理念为指引,加大科学与数学、技术、艺术、工程等领域知识的有机融合,使小学生在科学课堂上建立完善的知识体系,开阔学生知识视野,实现学生全方面发展。

渗入STEAM教育理念 加强学生解决实际问题能力

数学来源于生活,而数学学习的最终目的也是能够在实际生活中有效应用。在课堂教学中,教师践行STERM教育理念,通过灵活多样的方法激发学生的数学学习兴趣,为学生数学素养形成、能力得到提高起到促进作用。还要引导学生正确认识学习数学的目的,激发应用意识,提高他们应用数学知识解决实际问题的能力。

Importance of risk assessment,endoscopic hemostasis,and recent advancements in the management of acute non-variceal upper gastrointestinal bleeding

Acute non-variceal upper gastrointestinal bleeding(ANVUGIB)is a common medical emergency in clinical practice.While the incidence has significantly reduced,the mortality rates have not undergone a similar reduction in the last few decades,thus presenting a significant challenge.This editorial outlines the key causes and risk factors of ANVUGIB and explores the current standards and recent updates in risk assessment scoring systems for predicting mortality and endoscopic treatments for achieving hemostasis.Since ANUVGIB predominantly affects the elderly population,the impact of comorbidities may be responsible for the poor outcomes.A thorough drug history is important due to the increasing use of antiplatelet agents and anticoagulants in the elderly.Early risk stratification plays a crucial role in deciding the line of management and predicting mortality.Emerging scoring systems such as the ABC(age,blood tests,co-morbidities)score show promise in predicting mortality and guiding clinical decisions.While conventional endoscopic therapies remain cornerstone approaches,novel techniques like hemostatic powders and over-the-scope clips offer promising alternatives,particularly in cases refractory to traditional modalities.By integrating validated scoring systems and leveraging novel therapeutic modalities,clinicians can enhance patient care and mitigate the substantial morbidity and mortality associated with ANVUGIB.

Outpatient management of obscure gastrointestinal bleeding:A new perspective in high-risk patients

Mid-gastrointestinal bleeding accounts for approximately 5%-10%of all gastrointestinal bleeding cases,and vascular lesions represent the most frequent cause.The rebleeding rate for these lesions is quite high(about 42%).We hereby recommend that scheduled outpatient management of these patients could reduce the risk of rebleeding episodes.

The mechanisms of thermal solidification agent promoting steam diversion in heavy oil reservoirs

At high cycles of steam huff&puff,oil distribution in reservoirs becomes stronger heterogeneity due to steam channeling.Thermal solidification agent can be used to solve this problem.Its solution is a lowviscosity liquid at normal temperature,but it can be solidified above 80℃.The plugging degree is up to 99%at 250℃.The sweep efficiency reaches 59.2%,which is 7.3%higher than pure steam injection.In addition,simultaneous injection of viscosity reducer and/or nitrogen foams can further enhance oil recovery.The mechanism of this technology depends on its strong plugging ability,which changes the flowing pattern of steam to effectively mobilize remaining oil.Viscosity reducer and nitrogen foams further expand the sweep range and extends the effective period.Therefore,thermal solidification agent can plug steam channeling paths and adjust steam flowing direction to significantly enhance oil recovery at high cycles of steam huff&puff.

基于STEAM理念联合PBL教学法在急诊医学教学中的应用研究

目的分析基于STEAM[S(science),T(technology),E(engineering),A(art),M(mathematics)]理念联合以问题为基础的教学法(problem base learning,PBL)在急诊医学教学中应用效果。方法选择2021年6月—2022年6月滨州医学院急诊科80名本临床医学专业实习生为研究对象,将其随机分为对照组、试验组,各40名。对照组接受传统教学,试验组接受基于STEAM理念联合PBL教学法。对比2组教学前后理论知识及实践操作考试成绩、实习生对教学的满意度、学习依从度及教学前后实习生职业特质评分。结果教学前,2组考核成绩对比,差异无统计学意义(P>0.05);教学3个月后,2组基础理论、实践操作考核成绩均明显提升,但试验组提升幅度更大,差异有统计学意义(P<0.001)。试验组实习生学习依从性(97.50%)高于对照组(85.00%),差异有统计学意义(P<0.001)。试验组教学方法、学术能力、带教态度管理质量评分高于对照组,差异有统计学意义(P<0.001)。教学前,2组实习生职业特质评分对比,差异无统计学意义(P>0.05);教学3个月后,试验组评分高于对照组,差异有统计学意义(P<0.001)。结论在急诊医学教学中,基于STEAM理念联合PBL教学法有利于提升实习生的综合能力,提高理论实践成绩和学习依从性。

面向新质人才需求的STEAM培育机制研究

教育是缓解新质生产力与人才供需矛盾的核心策略,而基础教育则是塑造新质人才不可或缺的基石。为夯实未来新质人才的培育基础,基础教育阶段教育工作者应紧密围绕新质人才的需求,构建一套高效的人才培育机制,助力学生顺利转型为新质人才。在这一过程中,复合型教育目标的引导、跨学科知识体系的重组以及个性化教育策略的定制,为STEAM教育在基础教育阶段赋能新质人才培育提供了强有力的支撑。为了满足新质人才培育的多维需求,教育工作者需从五个关键层面重新构建STEAM教育培育机制:核心培育理念的重塑、根本培育目标的明确、基础培育条件的强化、首要培育策略的制定和关键培育基石的稳固。为了推动STEAM教育在新质人才培育方面更好地适应数智化时代的发展,教育工作者也需采取一系列措施:确保STEAM教育的高效运行,完善其跨学科知识体系,构建虚实联通的STEAM教育空间,提升教师的STEAM素养,并构建一个充满活力的STEAM人才培育新生态。这些措施的实施,将有力推动STEAM教育在培育新质人才方面的创新与发展,为新时代的社会进步贡献力量。

基于STEAM理论的学龄前儿童益智类玩具设计研究

本文以设计出一套切合STEAM理论的益智玩具为目的,同时能够提升学龄前儿童的各项智力能力。通过文献查阅对STEAM理论进行深入分析,归纳出STEAM理论的4项特点,STEAM益智玩具应满足的5个方面。根据皮亚杰理论对儿童的分析,选择前运算阶段儿童为目标群体,归纳出该阶段儿童的4项益智需求。通过上述分析设计出一款STEAM益智玩具套装,为后续STEAM益智玩具设计提供了参考。

STEAM教育助力“双减”政策落地的现实困境与可为路径

STEAM教育是我国基础教育改革的一种趋势,也是助力“双减”政策落地的重要抓手。STEAM教育具有情境性、实践性、项目式、过程性、跨学科性等特征,为“双减”政策的落地提供了可能。STEAM教育助力“双减”政策落地面临课后服务质量无法保障,课堂教学质量提升效果不佳,STEAM教师胜任力不足,STEAM教育存在区域、城乡、校际差异等困境。STEAM教育助力我国“双减”政策落地可从强化综合实践活动设计,拓展课后服务内容;以项目式学习为抓手,提高课堂教学质量;注重STEAM教师培养,提高教师综合素质;注重特色发展,以数字化转型推进STEAM教育均衡发展四个方面着手。

STEAM教育视域下中学语文跨学科深度学习的策略研究

STEAM教育是一种基于建构主义的跨学科教育,是对时代挑战的回应。以STEAM教育理念为突破口,解决当今中学语文跨学科教学存在的目标模糊,忽视语文本位;学科叠加,缺乏有效整合;学习浅表,缺少思维深度三方面问题。在中学语文课堂中采用:把握基点,语文本位,开展专题研修;明确跨点,融通互动,进行整合探究;找准落点,合作生成,促进素养提升这三种方式,以更好的教促进更好地学,推动中学语文跨学科深度学习发生,提升学生语文核心素养,将学生培养成符合时代要求的全面发展的高素质人才。

STEAM教育理念下的项目式教学模式建构研究

随着社会的进步和科学的快速发展,社会对于创新型人才和复合型人才的需求越来越多。为了培养出更多符合社会需要、促进社会发展的人才,本文基于STEAM教育理念对项目式教学模式进行研究,从项目式教学的过程出发,构建“项目策划-项目执行-项目反馈”的教学模式,培养学生的创新思维以及解决问题的能力,试图为项目式教学提供新思路。

基于STEAM理念的冰雪文创设计教学与实践

目的在大力促进冰雪主题文艺创作、推广冰雪文化的政策背景下,研究冰雪文创设计教学与STEAM理念结合的方法并进行课程教学实践。方法挖掘冰雪文化资源,分析冰雪文化相关的背景和文创产品种类,分析冰雪文创产品设计教学中的挑战。以STEAM教育理念为理论支撑,从教师和学生2个视角探讨科学、技术、工程、艺术、数学5个学科综合应用于冰雪文创设计教学的方式。教师首先运用该理念进行设计理论教学,然后通过布置并指导学生完成设计任务进行设计实践教学,最后以太阳岛风景区冰雪文创IP设计为例,引导学生用STEAM理念探索设计创意转化的方式,解决文创设计中的问题并完成设计。结论STEAM理念与冰雪文创设计教学融合的模式,将美育融入专业课程教学,有助于提高学生的跨学科思维能力、创新能力和设计实践能力。同时探索了冰雪文化知识转化为创意灵感的新路径,也为冰雪文化的传承和传播提供了新思路。

Efficacy and safety of over-the-scope-clips in the therapy of acute nonvariceal upper gastrointestinal bleeding:Meta-analysis

BACKGROUND Acute nonvariceal upper gastrointestinal bleeding(ANVUGIB)is a frequent lifethreatening acute condition in gastroenterology associated with high morbidity and mortality.Over-the-scope-clip(OTSC)is a new endoscopic hemostasis technique,which is being used in ANVUGIB and is more effective.AIM To summarize and analyze the effects of the OTSC in prevention of recurrent bleeding,clinical success rate,procedure time,hospital stay,and adverse events in the treatment of ANVUGIB,to evaluate whether OTSC can replace standard endoscopic therapy as a new generation of treatment for ANVUGIB.METHODS The literature related to OTSC and standard therapy for ANVUGIB published before January 2023 was searched in PubMed,Web of Science,EMBASE,Cochrane,Google,and CNKI databases.Changes in recurrent bleeding(7 or 30 days),clinical results(clinical success rate,conversion rate to surgery,mortality),therapy time(procedure time,hospital stay),and adverse events in the OTSC intervention group were summarized and analyzed,and the MD or OR of 95%CI is calculated by Review Manager 5.3.RESULTS This meta-analysis involved 11 studies with 1266 patients.Total risk of bias was moderate-to-high.For patients in the OTSC group,7-and 30-days recurrent bleeding rates,as well as procedure time,hospital stay,and intensive care unit stay,were greatly inhibited.OTSC could significantly improve the clinical success rate of ANVUGIB.OTSC therapy did not cause serious adverse and was effective in reducing patient mortality.CONCLUSION OTSC may provide more rapid and sustained hemostasis,and thus,promote recovery and reduce mortality in patients with ANVUGIB.In addition,the safety of OTSC is assured.

STEAM教育理念下电场自动测绘仪的开发

将静电场教学实践中遇到的问题,作为课外拓展课题研究是新工科人才培养的有效方式之一。本文基于STEAM教育理念,采用项目式学习,以学生为主体,以跨学科融合和创新为导向,制定教学目标和教学方法。将物理理论和实验创新有机融合,引导学生结合单片机技术和Matlab程序,设计出新型可视化电场自动测绘仪。该仪器操作简便高效,测量精度高,还能直观展示电场的动态变化。而学以致用的过程,提高了学生的创新能力和知识综合运用能力,也为高校的教学改革提供了新思路。

Computed tomography for prediction of esophageal variceal bleeding

This letter to the editor relates to the study entitled“The role of computed tomography for the prediction of esophageal variceal bleeding:Current status and future perspectives”.Esophageal variceal bleeding(EVB)is one of the most common and severe complications related to portal hypertension(PH).Despite marked advances in its management during the last three decades,EVB is still associated with significant morbidity and mortality.The risk of first EVB is related to the severity of both PH and liver disease,and to the size and endoscopic appearance of esophageal varices.Indeed,hepatic venous pressure gradient(HVPG)and esophagogastroduodenoscopy(EGD)are currently recognized as the“gold standard”and the diagnostic reference standard for the prediction of EVB,respectively.However,HVPG is an invasive,expensive,and technically complex procedure,not widely available in clinical practice,whereas EGD is mainly limited by its invasive nature.In this scenario,computed tomography(CT)has been recently proposed as a promising modality for the non-invasive prediction of EVB.While CT serves solely as a diagnostic tool and cannot replace EGD or HVPG for delivering therapeutic and physiological information,it has the potential to enhance the prediction of EVB more effectively when combined with liver disease scores,HVPG,and EGD.However,to date,evidence concerning the role of CT in this setting is still lacking,therefore we aim to summarize and discuss the current evidence concerning the role of CT in predicting the risk of EVB.

融合STEAM理念的“细胞工程”课程教学改革探索

“细胞工程”是生物技术、生物工程等生物专业的核心基础课程之一。面向新工科建设背景下对人才培养的新要求,基于STEAM教育理念,结合“细胞工程”课程特点,坚持立德树人根本任务,以学生为中心,面向生物医药产业的发展需求,对课程的教学目标、教学设计、教学体系、教学理念、教学方法、教学考核评价等进行改革,旨在激发学生的求知欲,培养学生多学科交叉融合理念,使学生善于从多学科角度思考问题、提出问题、分析问题和解决问题,提高学生创新思维,提高课程教学效果。