Application of SYNTAX and its Derivative Scores in the Selection of Revascularization Strategies for Complex Coronary Heart Disease

Complex coronary heart disease(CHD)has become a hot spot in medicine due to its complex coronary anatomy,variable clinical factors,difficult hemodynamic reconstruction,and limited effect of conservative drug treatment.Identifying complex CHD and selecting optimal treatment methods have become more scientific as revascularization technology has improved,and coronary risk stratification scores have been introduced.SYNTAX and its derivative scores are decision-making tools that quantitatively describe the characteristics of coronary lesions in patients based on their complexity and severity.The SYNTAX and its derivative scores could assist clinicians in rationalizing the selection of hemodynamic reconstruction treatment strategies,and have demon-strated outstanding value in evaluating the prognosis of patients with complex CHD undergoing revascularization treatment.The authors in this article summary the practical application of SYNTAX and its derivative scores in complex CHD in order to deepen the understanding of the relationship between the choice of different revascularization strategies and SYNTAX and its derived scores in complex CHD and provide a further reference for clinical treatment of complex CHD.

The Relationship between Language Learning Strategy and the CET-6 Scores

It investigates the relationship between language learning strategy and the CET-6 scores of students majoring in English as a foreign language(EFL). Participants consists of a volunteer pool of 45 second-year English major students at Tianjin Polytechnic University. A revised version 7.0 of Oxford's(1990, pg. 293-300) Strategy Inventory for Language Learning(SILL)and the CET-6 are administered as measures of learning strategy and the CET-6 scores. An analysis of ANOVA and Multiple Correlation is conducted to examine the relationships among six types of learning strategies and scores of CET-6. Results of this analysis reveals that metacognitive strategies and affective strategies are two major language learning strategies that preferred by the participants in the English learning process. While metacognitive strategies and affective strategies preferred by the participants do not have a statistically significant correlation with the scores of CET-6. It is the memory strategies and social strategies that have a significant correlation with the scores of CET-6.

Empirical Research on Quality Improvement and Effect Increase of Rural Tourist Destination Under the Strategic Background of Rural Revitalization: A Case Study of Xishan District, Kunming City, Yunnan Province

As one of important channels in rural revitalization and development, rural tourism obtains a lot of remarkable achievements in rural development. However, relatively single product and homogenized development model make competition gradually intensify, and many once glorious rural tourist destinations gradually decline. Xishan District of Kunming City of Yunnan Province is taken as research object in this paper. Via literature research, field survey and depth interview, development process, status quo and existing problems of its rural tourism are deeply explored. Based on above research results, development idea, strategy and countermeasure for quality improvement and effect increase of traditional rural tourism destination are proposed, and cooperative development, mutual benefit and win-win are taken as the ultimate development goals.

Hypertension Associated with Atherosclerosis Risk Factors in Patients of Family Health Strategy Highlighting the Framingham Risk Score

The Systemic Arterial Hypertension (SAH) stands out among the chronic non-transmissible pathologies that impact the cause and/or aggravation of cardiovascular diseases (CVD) on a global level, as the disease is an underestimated disorder due to non-perceptive symptoms and associated with factors and risk markers of another CVD. Therefore, establishing the risk of progression and aggravation of the SAH, according the Framingham Risk Score (FRS), allows to reducing morbidity and improving preventative measures for DCVs. This observational and transversal study approaches the data collection of patient records at the Health Family Strategy of Senhor do Bonfim, BA, which established differences by descriptive and inferential statistical analysis (correlation and regression). The aspects of hypertension associated with risk factors for atherosclerosis were analyzed, determining the risk of developing cardiovascular events in 10 years by FRS. From 432 families, 746 patients were selected, of which 340 are hypertensive individuals (SAH = 45.57%) and 406 (NSAH = 54.42%) non-hypertensives. Among the SAH the majority (31.17%) was in the age range of 63 - 77, but, in both groups, women were in stronger number. There was greater prevalence in SAH for all the characteristics analyzed, smoking (13.20%), sedentary (29.41%) and cardiovascular accident (22.60%). The SAH group is more susceptive to the CVD progress in 10 years by FRS (P < 0.0001 ANOVA). In the NSAH group, there were significant associations among all the variables analyzed as was expected, without differences between the linear correlation and regression, indicating the physio-metabolic equilibrium of the factors and markers evaluated by FRS. Already in SAH group, despite the correlations have been significant too, the regression analysis revealed that only Total Cholesterol (P = 0.0086);LDL (P < 0.0001), Glucose (P < 0.0006) and Age (P < 0.0001) have significative association with FRS. So, these factors and markers deserve more attention upon the health staff of Health Family Strategy, in the SAH course at studied population, attempt the highest cardiovascular risk by FRS (2.5 to 2.8 times) to SAH. The monitoring of high-risk patients should prioritize the lifestyle changes, employing preventive measures to SAH and CVD and atherosclerosis.

A universal charge-compensating strategy for high-energy-density pseudocapacitors

For pseudocapacitive electrode materials(PseEMs),despite much progress having been made in achieving both high power density and high energy density,a general strategy to guide the enhancement of intrinsic capacitive properties of PseEMs remains lacking.Here,we demonstrate a universal chargecompensating strategy to improve the charge-storage capability of PseEMs intrinsically:ⅰ) in the electrolyte with anion as charge carriers(such as OH-),reducing the multivalent cations of PseEMs into lower valences could create more reversible low-to-high valence redox cou ples to promote the intercalation of the anions;ⅱ) in the electrolytes with cation as charge carriers(such as H^(+),Li^(+),Na^(+)),oxidizing the multivalent cations of PseEMs into higher valences could introduce more reversible high-to-low valence redox couples to promote the intercalation of the cations.And we demonstrated that the improved intrinsic charge-storage capability for PseEMs originates from the increased Faradaic charge storage sites.

Therapeutic effect of regulating autophagy in spinal cord injury: a network meta-analysis of direct and indirect comparisons

Objective:An increasing number of studies indicate that autophagy plays an important role in the pathogenesis of spinal cord injury,and that regulating autophagy can enhance recovery from spinal cord injury.However,the effect of regulating autophagy and whether autophagy is detrimental or beneficial after spinal cord injury remain unclear.Therefore,in this study we evaluated the effects of autophagy regulation on spinal cord injury in rats by direct and indirect comparison,in an effort to provide a basis for further research.Data source:Relevant literature published from inception to February 1,2018 were included by searching Wanfang,CNKI,Web of Science,MEDLINE(OvidSP),PubMed and Google Scholar in English and Chinese.The keywords included"autophagy","spinal cord injury",and"rat".Data selection:The literature included in vivo experimental studies on autophagy regulation in the treatment of spinal cord injury(including intervention pre-and post-spinal cord injury).Meta-analyses were conducted at different time points to compare the therapeutic effects of promoting or inhibiting autophagy,and subgroup analyses were also conducted.Outcome measure:Basso,Beattie,and Bresnahan scores.Results:Of the 622 studies,33 studies of median quality were included in the analyses.Basso,Beattie,and Bresnahan scores were higher at 1 day(MD=1.80,95%CI:0.81-2.79,P=0.0004),3 days(MD=0.92,95%CI:0.72-1.13,P<0.00001),1 week(MD=2.39,95%CI:1.85-2.92,P<0.00001),2 weeks(MD=3.26,95%CI:2.40-4.13,P<0.00001),3 weeks(MD=3.13,95%CI:2.51-3.75,P<0.00001)and 4 weeks(MD=3.18,95%CI:2.43-3.92,P<0.00001)after spinal cord injury with upregulation of autophagy compared with the control group(drug solvent control,such as saline group).Basso,Beattie,and Bresnahan scores were higher at 1 day(MD=6.48,95%CI:5.83-7.13,P<0.00001),2 weeks(MD=2.43,95%CI:0.79-4.07,P=0.004),3 weeks(MD=2.96,95%CI:0.09-5.84,P=0.04)and 4 weeks(MD=4.41,95%CI:1.08-7.75,P=0.01)after spinal cord injury with downregulation of autophagy compared with the control group.Indirect comparison of upregulation and downregulation of autophagy showed no differences in Basso,Beattie,and Bresnahan scores at 1 day(MD=-4.68,95%CI:-5.840 to-3.496,P=0.94644),3 days(MD=-0.28,95%CI:-2.231-1.671,P=0.99448),1 week(MD=1.83,95%CI:0.0076-3.584,P=0.94588),2 weeks(MD=0.81,95%CI:-0.850-2.470,P=0.93055),3 weeks(MD=0.17,95%Cl:-2.771-3.111,P=0.99546)or 4 weeks(MD=-1.23,95%Cl:-4.647-2.187,P=0.98264)compared with the control group.Conclusion:Regulation of autophagy improves neurological function,whether it is upregulated or downregulated.There was no difference between upregulation and downregulation of autophagy in the treatment of spinal cord injury.The variability in results among the studies may be associated with differences in research methods,the lack of clearly defined autophagy characteristics after spinal cord injury,and the limited autophagy monitoring techniques.Thus,methods should be standardized,and the dynamic regulation of autophagy should be examined in future studies.

Mathematical Model of Dynamic Operation and Optimum Control of Billet Reheating Furnace

This paper provides a mathematical model for the billet reheating process in furnace.A new optimum method is brought up that the objective function is the integral value of enthalpy increasing process of a billet.Different delays are simulated and calculated,some proper delay strategies are ob- tained.The on-line computer control model is de- veloped.The real production conditions simulated, the temperature deviation of drop out billet from the target temperature is kept within±15℃.

Modelling and Sporting Performance in Karate

Karate is a competition combat sport that will be present at the Olympic Games during the trials in Tokyo in 2020. Within its inner logic, this activity implies a system of scores that may lead to a specific modelling, to be unveiled and used when dealing with the search for performance. If we consider that various strategies all seem to be able to lead to victory within that zero-sum game, might there be a possible Nash equilibrium to look for, aiming at favouring some of them and minimising gains and losses？ Must one privilege offensive or defensive behaviours, provoke or wait？ In relation to new sporting rules, 309 combats have been observed in the light of their system of scores and our result reveal perspectives for training. Even though the results remain questionable and are still to be completed, they enable us to highlight propositions as to a modelling through the work of Biechy. The suboptimal equilibrium thus highlighted reminds us that this game remains solely based on a system of rivalry, within which predefined strategy and initiative are to be articulated.

Increasing Ventilation by Passive Strategies: Analysis of Indoor Air Circulation Changes through the Utilization of Microclimate Elements

A demand for renewable alternatives that would be able to deal with the problems related to well-being is directly linked to the world’s growing needs to save energy and reduce environmental costs. For a project implementation addressing these issues, it is essential to know the climatic conditions of the target area. Taking natural ventilation, climatic factors, and renewable alternatives as important sources of comfort, in this work, passive strategies, through the utilization of microclimate elements as well as the location of outside obstacles, were imposed on an initial and specific project. The objective was to introduce obstacles which could interfere in the field of external wind and evaluate whether this outside intervention is able to make changes in indoor air circulation. The wind fields for the studied cases were obtained by computational simulations, and their consequences were analyzed to attain thermal comfort. The method adopted to obtain the wind fields was a Petrov-Galerkin type method, which is a stabilized mixed finite element method of the Navier-Stokes equations considering the incompressibility and formulated in primitive variables, velocity and pressure. The obtained results point to the solutions that promote the increase or decrease of the wind-field intensity.

A Study on English Vocabulary Learning Strategies of College Students

The present study attempts to investigate Chinese non-English majors' vocabulary learning strategies.The descriptive statistics is carried out on the learners' vocabulary learning strategies;a correlational study is conducted between the students' vocabulary learning strategies and their vocabulary test scores.The result shows that students still prefer to learn vocabulary through the traditional way and that the dictionary strategies and rehearsal strategies are negatively related to vocabulary test scores,while all the other five categories are positively related to them.The pedagogical implications of this study are suggested for college teachers' instructions of vocabulary learning strategies.

基于利益相关者理论的企业E-learning管理研究

作为现代企业培训的主要方式,E-learning在得到普遍应用的同时,其管理中存在的问题也日益暴露出来。只有通过利益相关者理论实现"以人为本"的理念,才能充分发挥企业E-learning的作用,让员工在自己的工作岗位上获得成功的同时,实现共同的商业目的。

铜仁地区三化螟Tryporyza incertulas(Walker)种群上升原因与防治对策研究

近年来,贵州省东部和湖南省西部地区三化螟种群上升的原因主要有:迟熟中稻品种的播种期推迟,使水稻的孕穗、抽穗期与三代螟卵盛孵期相遇;越冬虫源未能很好清理,冬后未及时灌水翻耕,残存活虫量大;部分稻田由于栽培管理不当,造成前期“坐蔸”,生育期延迟;药剂防治工作不及时等。防治对策以“避害”为中心环节,部分避不开的稻田及时开展药剂防治。药治策略为:重点防治一代,挑治二代,狠治三代。经三年的防治实践,三化螟年诱蛾量从1989年的13325头下降到1991年的234头,越冬后亩残存活虫量从1989年的1042.1头下降到1991年的2.8头,基本上控制了危害。

Non-classical phenotypes of autoimmune hepatitis and advances in diagnosis and treatment

Non-classical manifestations of autoimmune hepatitis can delay diagnosis and treatment. Our aims were to describe the clinical phenotypes that can confound the diagnosis, detail scoring systems that can ensure their recognition, and outline advances in treatment that can improve their outcome. Prime source and review articles in English were selected throuqh Medline from 1970-2008 and assimilated into personal libraries spanning 32 years. Acute severe or asymptomatic presentations and atypical histological findings,including centrilobular zone 3 necrosis and concurrent bile duct changes, are compatible with the diagnosis. Cholangiographic abnormalities may be present in children and adults with the disease, and autoimmune hepatitis must be considered in patients without autoantibodies or with antimitochondrial antibodies and no other cholestatic features. Asymptomatic patients frequently become symptomatic; mild disease can progress; and there are no confident indices that justify withholding treatment. Two diagnostic scoring systems with complementary virtues have been developed to evaluate patients with confusing features. Normal liver tests and tissue constitute the optimal end point of treatment, and the first relapse is an indication for long- term azathioprine therapy. Cyclosporine, tacrolimus and mycophenolate mofetil are promising salvage therapies,and budesonide with azathioprine may be a superior frontline treatment. We conclude that the non-classical phenotypes of autoimmune hepatitis can be recognized promptly, diagnosed accurately, and treated effectively.

Monitoring Day and Night-Time Situation of Urban Heat Island and Possible Adaptation Measures in Douala, Cameroon

Urban Heat Island (UHI) has the potential to directly influence the health and welfare of urban residents. The study employed a traditional method called “paired measurement program” to analyze the effects of four land use/land- cover patterns on intra-urban air temperature variations in the Douala Metropolis, Cameroon under different atmospheric conditions. This study also investigated the possible adaptation measures employed by the inhabitants to combat the urban heat island effects. The result revealed a variation in the temperature of the selected transects. There was a mix of cool and heat islands by day, especially during rainy seasons. The daytime variations were strongly correlated to the amount of tree shading. It was also observed that the temperature gradient was formed at the Central Business District (CBD) and progressively lowered to the suburbs. The thermal comfort classification for the area ranges between 25.4°C and 27°C, which is a class where over 50% of the population feels stressed;and the range of 32°C and above, where most of the population suffers discomfort. In order to investigate the possible adaptation measures employed by the inhabitants of Douala, two hundred and fifty questionnaires were distributed and analyzed using descriptive statistics. The result revealed that the inhabitants use various coping strategies in order to adapt to UHI effects. The strategies identified include;stay indoors, drink plenty of water, wear light clothing, go to an A/C location, take a cool shower, avoid outdoors, and wear a hat or cover head. The widely used coping strategy identified is drinking plenty of water. The expensive nature of A/C makes it the least used coping strategy.

Uniform Pricing Strategy vs. Price Differentiation Strategy in the Presence of Cost Saving and Demand Increasing

Price differentiation or discrimination strategy has been regarded as the best choice for firms with online and offline channels, however, recent years often witnessed the practices of the uniform pricing strategy. This paper aims to address the question whether the uniform pricing strategy may be better for the manufacturer, when the uniform pricing strategy has a positive impact on increasing the ciistomer demand and reducing the operations cost. The research shows that the uniform pricing strategy can be bet ter than the price differentiation strategy when the cost saving and demand increasing are large enough or the consumers' acceptance of online channel lies in a certain interval. Moreover, the manufac tu rers or brand owners need a tradeoff bet ween the benefit from online channel and the negative impact from the offline channel when they implement the price differentiation strategy. Finally, the authors obtain some managerial insights and implications based on the numerical analyses, which are in line with the phenomena in practice.

Applying Score Reliability Fusion to Bi-Model Emotional Speaker Recognition

Emotion mismatch between training and testing is one of the important factors causing the performance degradation of speaker recognition system. In our previous work, a bi-model emotion speaker recognition (BESR) method based on virtual HD (High Different from neutral, with large pitch offset) speech synthesizing was proposed to deal with this problem. It enhanced the system performance under mismatch emotion states in MASC, while still suffering the system risk introduced by fusing the scores from the unreliable VHD model and the neutral model with equal weight. In this paper, we propose a new BESR method based on score reliability fusion. Two strategies, by utilizing identification rate and scores average relative loss difference, are presented to estimate the weights for the two group scores. The results on both MASC and EPST shows that by using the weights generated by the two strategies, the BESR method achieve a better performance than that by using the equal weight, and the better one even achieves a result comparable to that by using the best weights selected by exhaustive strategy.

中国西南地区粮食增产潜力、影响因素与策略研究

西南地区是中国粮食生产战略大后方,提高西南地区粮食产能对确保中国粮食安全和产销平衡具有重要意义。在剖析西南地区粮食产业发展现状和存在问题基础上,采用Tobit模型分析西南地区粮食增产因子的影响系数,并探究西南地区粮食未来增产潜力。结果显示:(1)西南地区粮食生产呈现“播面减少”“产量增加”的双向走势,生态环境脆弱、耕地细碎化及粮经争地矛盾等给粮食增产带来巨大挑战;(2)影响西南地区粮食增产的主要因素依次为复种指数(影响系数0.42)、机械化程度(影响系数0.397)、科学施肥量(影响系数0.346)和财政支农力度(影响系数0.134);(3)到2027年,西南地区粮食产量有望达到7 852万t,5年间预计增长2.5%。基于上述结论,建议采取推广粮经复合模式、加强良种良技研发应用、加大对生产经营主体的扶持力度、建立安全预警机制等措施提升西南地区粮食产量。

Adolescents’ happiness-increasing strategies, temperament, and character: Mediation models on subjective well-being

In order to predict Subjective Well-Being (SWB) or happiness two of the major determinants may be 1) A genetic set point (which reflects personality) and 2) Current intentional activities (behavioral, cognitive, and motivational). In this context, personality can be considered as psycho-biological—composed of temperament (i.e., what grabs our attention and how intensely we react) and character (i.e., a reflection of personal goals and values). The present study examined how adolescents’ personality and intentional happiness-increasing strategies, measured at one point in time, are related to SWB measured one year later. Results show that temperament (Harm Avoidance) and character dimensions (Self-directedness) predicted SWB. Moreover, strategies such as active leisure (e.g., engaging in sports) and instrumental goal pursuit (e.g., study) also predicted SWB at the end of the school year. The strategy of Mental Control (i.e., an ambivalent effort to both avoid and contemplate negative thoughts and feelings), which was related to Harm Avoidance and Self-Directedness, mediated the relationship between these two personality dimensions and SWB.

基于体验记忆模型的服务触点优化策略研究

目的将体验记忆模型应用于服务触点的优化研究,结合体验与记忆两个因素筛选需优化服务触点(即威胁触点),建立基于体验记忆模型的服务触点优化策略。方法首先,基于特定服务系统梳理并确定用户群,建立用户画像。基于行为追踪获取服务触点,并采取量表法对服务触点进行体验评价。其次,根据艾宾浩斯遗忘曲线确定记忆评分的3个时间点,选取定量用户并分别对服务触点进行记忆评分,结合服务触点体验评价构建体验记忆分区图,明确服务系统中的威胁触点。最后,结合用户需求,提出威胁触点的优化建议,并最终完成服务触点原型输出。结果以公园骑行服务触点优化为例证,验证了该策略的可靠性。结论体验记忆模型可有效筛选服务触点,提高设计效率,降低服务优化成本。

大庆油田SEC储量储采形势及增储策略

大庆油田目前已进入双特高后期开发阶段,储采比逐渐降低,SEC储量替换率仅为0.4左右,增储与稳产需求的矛盾日益加剧。通过对大庆油田目前SEC储采现状、增储特点、影响因素进行分析,认为资源品质下降、长期低油价、成本上升以及评估精细程度不足这4个方面是造成储采失衡的主要原因。为改善储采状况,大庆油田形成了较为有效的增储做法,结合大庆油田实际提出了加强技术创新与应用、提升新区勘探与开发效率、优化天然气资源利用、强化精细管理与成本控制、融入绿色发展与新能源等实现储采平衡的工作方向及增储策略。研究成果为东部同类老油田的长远高质量发展提供决策参考。