Successful reversal of ostomy 13 years after Hartmann procedure in a patient with colon cancer: A case report

BACKGROUND The Hartmann procedure is currently recognized as a common,safe,and feasible surgical procedure.However,its reversal rate is low,and the optimal timing for Hartmann reversal surgery is controversial.CASE SUMMARY A 65-year-old man came to our hospital with a complaint of an intestinal fistula next to the stoma.The patient had undergone a Hartmann procedure 13 years prior.We performed colonoscopy,computed tomography,and other diagnostics before successfully reversing the stoma.CONCLUSION Although the optimal time for Hartmann procedure reversal is controversial,time may ultimately not be a factor in the success of reversal.

The Openness Degree Study of the Jiaoshiba Shale Gas, Sichuan Basin, China–Potential Factor Responsible for Reversed Isotope Series

Objective Reversed alkane δ;C and δ;H values in many prolific shale plays all over the world have aroused much attention in the study of the formation mechanism of reversed isotope series in alkanes in the past few years（Zou Caineng et al., 2016）. Although many researchers have put forward different hypotheses, the mechanism has not been well understood yet. The openness degree of oil and gas system

Case Study on Critical Success Factors of Running Scrum

Agile development 12 principles, and adaptive project management life cycle model are applied to case study of J group, the critical success factors of running Scrum are identified as follows: 1) explicit the process of project management and a self-managing group with Scrum;2) professional agile development and release capability;3) building learning organization. J group as a pioneer Scrum agile software development practices, realizes the productivity of significant promotion and cost reduction, accelerates the product to the market, improves customer satisfaction and achieves a more transparent development process and higher predictive capability. The study aims to improve the success rate of the running Scrum.

Study and ICH validation of a reverse-phase liquid chromatographic method for the quantification of the intact monoclonal antibody cetuximab

Cetuximab （CTX） is a potent chimeric mouse/human monoclonal antibody （mAb） approved worldwide for treatment of metastatic colorectal cancer. Among the various biological and physical analyses per- formed for full study on this biopharmaceutic, the determination of the concentration preparations throughout manufacturing and subsequent handling in hospital is particularly relevant. In the present work, the study and validation of a method for quantifying intact CTX by reverse-phase high-perfor- mance liquid chromatography with diode array detection （（RP）HPLC/DAD） is presented. With that end, we checked the performance of a chromatographic method for quantifying CTX and conducted a study to validate the method as stability-indicating in accordance with the International Conference on Harmo- nization guidelines （ICH） for biotechnological drugs; therefore, we evaluated linearity, accuracy, preci- sion, detection and quantification limits, robustness and system suitability. The specificity of the method and the robustness of the mAb formulation against external stress factors were estimated by compre- hensive chromatographic analysis by subjecting CTX to several informative stress conditions. As de- monstrated, the method is rapid, accurate, and reproducible for CTX quantification. It was also suc- cessfully used to quantify CTX in a long-term stability study performed under hospital conditions.

A PRELIMINARY STUDY ON THE THEORY OF THE SECOND AND THIRD ORDER DERIVATIVE ADSORPTION CHRONOPOTENTIOMETRY FOR A REVERSIBLE REACTION

The equations of the second and third order derivative curves of time with respect to potential for a reversible process in adsorption chronopotentiometry are derived and experimentally verified.

Patients’ perceptions, health and psychological changes with obesity treatment: Success and failure in a triangulation study

The present study aims to understand changes in health problems, health complaints and coping strategies, during the obesity treatment process with qualitative and quantitative data. Thirty bariatric patients were interviewed before bariatric surgery and at a 12-month follow-up, and fulfilled self-report measures about health problems, health complaints and coping strategies before surgery, at 6-and 12-month follow-ups. Before surgery, failure cases differ from success on the conceptualization of obesity, However, there are no other differences between groups. At 6-and 12-month follow-ups, failure cases had the highest BMI, health problems and complaints and less % EWL than success cases. One year after the surgery, one in each three persons did not lose the expected weight, i.e., are failure cases. Before surgery, there are no differences between success and failure cases in the report of health problems, health complaints and coping strategies, but they have different conceptualizations of their obesity and treatment. One year after the surgery, success cases understood bariatric surgery as an important moment in their lives related to their expected results, whereas failures valued unexpected dimensions and still waiting for a miracle surgery without their personal commitment. Accordingly, it is necessary to consider lifestyle changes in the obesity treatment process.

云南晋宁某低品位磷矿选矿技术实验研究

云南晋宁某低品位胶磷矿属于混合型磷块岩,其w(P2O5)为18.45%,w(MgO)2.39%,w(SiO2)35.88%。在常温条件下,当磨矿细度≤0.074 mm占97.18%时,采用“正-反浮选工艺流程”对该矿进行选别。通过闭路实验获得w(P2O5)28.51%、w(MgO)0.95%、w(SiO2)19.70%、P2O5回收率为81.70%的精矿指标,实现了该矿的有效分选。

“一村一名大学生计划”对农村创业成功的影响研究

兴大业,必先用人。人才振兴是推进乡村振兴的重要引擎力量。本文基于教育部“一村一名大学生计划”评选出的69个案例,运用扎根理论,通过开放式编码、主轴式编码以及选择式编码,分析出“一村一名大学生计划”对农村创业成功的核心影响因素,并结合社会资本理论与自我效能理论,探究了“一村一名大学生计划”实现农村创业成功的路径。结果发现:“一村一名大学生计划”的开展,具有增加农村创业者社会资本和专业知识、提高创业者个人能力的功能,从而帮助农村创业者有效地识别创业机会,获取更优质的创业资源,做出科学正确的创业行为,最终实现创业成功。同时,基于所得结果,归纳、构建出“一村一名大学生计划”影响农村创业成功的机理模型,据此提出未来助力“乡村振兴”的相关建议。

臀位外倒转术在足月臀位妊娠产妇中的应用及矫正成功影响因素分析

目的探讨臀位外倒转术在足月臀位妊娠产妇中的应用,并分析其矫正成功影响因素。方法选取2020年1月至2023年1月收治的足月单胎臀位妊娠产妇162例,根据干预情况将其分为研究组(n=69例)和对照组(n=93例)2组。统计比较2组分娩方式、臀位矫正成功情况及治疗过程中并发症发生情况;采用单因素和多因素Logistic回归分析探讨足月臀位妊娠产妇臀位外倒转术矫正成功影响因素。结果研究组阴道分娩率和臀位矫正成功率[57/69,82.61%;47/69,68.12%]均高于对照组[2/93,2.15%;28/93,30.11%](P<0.01)。治疗过程中,研究组胎盘早剥、脐带绕颈、头盆不称发生率和围产期新生儿住院率[1/69,1.45%;2/69,2.90%;1/69,1.45%;1/69,1.45%]低于对照组[9/93,9.68%;12/93,12.90%;10/93,10.75%;11/93,11.83%](P<0.05)。多因素Logistic回归分析结果显示,新生儿体质量和产次是足月臀位妊娠产妇臀位外倒转术矫正成功的独立影响因素(P<0.05,P<0.01)。结论足月臀位妊娠产妇应用臀位外倒转术可提高阴道分娩率,降低并发症发生率,而新生儿体质量和产次是影响该技术矫正成功的主要因素。

微量营养素与骨坏死的因果关系:来自双向孟德尔随机试验的证据

背景:骨坏死是临床常见的难治性疾病,有观察性研究表明微量营养元素可能对骨坏死的预后存在一定的促进作用,然而微量营养元素与骨坏死具体的因果关联尚未可知。目的:利用大规模人群全基因组关联研究(GWAS)的汇总数据,通过孟德尔随机化的方法探究微量营养元素与骨坏死之间的因果关联,为临床诊疗提供帮助。方法:从IEU OpenGWAS数据库、GWAS catalog数据库、FinnGen数据库提取需要的暴露和结局数据(钙、镁、铁、维生素E、胡萝卜素、视黄醇与骨坏死)。对数据进行双向孟德尔随机化分析,以逆方差加权法(inverse-variance weighted)为主要的研究方法,加权中位数法(weighted median)、简单模式法(simple mode)、加权模式方法(weighted mode)和MR-Egger回归对结果进行补充;然后通过敏感性分析验证数据的可靠性。结果与结论:①结果发现,血清铁浓度与骨坏死存在正相关关系,而其他微量营养元素未发现相关,且所有数据都不存在反向因果关系;②敏感性分析结果表明因果关系稳健;③通过孟德尔随机化方法,此次研究提供了血清铁浓度和骨坏死之间存在因果关系的证据;了解微量营养元素与骨坏死的因果关系,有助于临床上对骨坏死的诊疗,具有重要的临床意义。

羽毛球逆转率两局率在新旧规则下的比较研究——以1989-2023年奥运会、世锦赛为例

研究目的:为探讨在世界高水平羽毛球比赛各单项中囊括新旧规则的数十年来的逆转现象,并对深入分析未来的比赛提供理论依据和参考,采用卡方检验验证了各单项比赛中逆转率和两局率的变化差异。研究方法:运用文献资料法、数理统计法对1989—2023年的共31届羽毛球个人世界大赛的所有正赛部分,共7743场的比赛结果进行分析。研究结果::新规则使所有单项比赛逆转率均有提升,其中双打项目均为显著及以上提升;新规则使所有单项比赛两局率均非常显著下降;新规则内部两阶段各单项逆转率和两局率除男双两局率外无显著变化;女双项目始终是逆转率最低和两局率最高的单项。

黄帝传说探源

20世纪二三十年代,疑古派学者提出层累地造成中国古史说,对传说时代的五帝史和夏史给予了全面否定,流波滔滔,至今未息。然细考文献,黄帝传说并非始于战国,早在西周即已出现,黄帝也不是层累造作的神话人物,而是中国上古时期部族共同体的一位杰出领袖。从最初的来源上说,黄帝传说是基于历史的真实而非想象的产物,只是历经几千年的沧桑岁月,历史本相不免失真走样,但其中蕴含着事实真相的果粒,不可一概视为虚妄而尽行弃之。可行的做法是精心鉴别这些传说性质的史料,去伪存真,考而后信,过滤出真实的历史信息,用于上古史的重建。充分结合文献和考古资料,深入探讨五帝时代中国早期文明形成的基因和路径,对于坚定文化自信,推动传统文化的创新和发展,无疑具有积极的意义。

CO hydrogenation combined with water-gas-shift reaction for synthetic natural gas production:a thermodynamic and experimental study

The hydrogenation of CO to synthetic natural gas (SNG) needs a high molar ratio of H2/CO (usually large than 3.0 in industry), which consumes a large abundant of hydrogen. The reverse dry reforming reaction (RDR, 2H2 + 2CO←→CH4 + CO2), combining CO methanation with water-gas-shift reaction, can significantly decrease the H2/CO molar ratio to 1 for SNG production. A detailed thermodynamic analysis of RDR reaction was carried out based on the Gibbs free energy minimization method. The effect of temperature, pressure. H2/CO ratio and the addition of H2O, CH4, CO2, O2 and C2H4 into the feed gas on CO conversion, CH4 and CO2 selectivity, as well as CH4 and carbon yield, are discussed. Experimental results obtained on homemade impregnated Ni/Al2O3 catalyst are compared with the calculations. The results demonstrate that low temperature (200-500 °C), high pressure (1-5 MPa) and high H2/CO ratio (at least 1) promote CO conversion and CH4 selectivity and decrease carbon yield. Steam and CO2 in the feed gas decrease the CH4 selectivity and carb on yield, and enhance the CO2 con tent. Extra CH4 elevates the CH4 content in the products, but leads to more carbon formation at high temperatures. O2 significantly decreases the CH4 selectivity and C2H4 results in the generation of carbon.

Reverse Design and Test of Non-circular Gear & Crank-Rocker & Gear Trains Weft Insertion Mechanism

For the purpose of obtaining satisfactory performance of the non-circular gear & crank-rocker & gear trains (NCCRG) weft insertion mechanism which was proposed in this paper, the ideal kinematic curve of this weft insertion mechanism was given, and the reverse solution models of this mechanism were established. A reverse design and simulation software was compiled based on Visual Basic 6.0 to obtain the mechanism parameters, including the pitch curves and tooth profiles of the non-circular gears. A test-bed of this mechanism was developed according to these parameters. The kinematic performance of this weft insertion mechanism was tested by high-speed video tape recorder with its corresponding video analytical software Blaster's MAS. And the test results were identical with the theoretical calculation. Compared with the conjugate cam weft insertion mechanism which is applied on TT96 rapier loom, under the condition of same weft insertion rate, the variation of acceleration of this mechanism is smaller. This novel weft insertion mechanism can meet the requirements of weft insertion on rapier looms with smooth and steady motion.

Reverse dedifferentiation of atrial cardiomyocytes after restoration of sinus rhythm from atrial fibrillation in goats

Objective Chronic atrial fibrillation （AF） results in dedifferentiation of atrial cardiomyocytes that plays an important role in the perpetuation of AF. In this study, we aimed to investigate the changes oftitin and a-smooth muscle actin （α-SMA） after long time of AF reversal. Methods Twenty-four goats were randomized into four groups： （1） sinus rhythm （SR）, （2） 3 months AF （3-too AF）, （3） 3 months SR after 3 months AF （3-mo post AF）, （4） 6 months SR after 3-mo AF （6-mo post AF）, with 6 in each group. By pacing on the anterior bottom of left atria appendage （LAA）, we established a goat model of chronic AF. Atria effective refractory period （AERP） was measured with electrophysiological methods. Ultra-structure was studied with echocardiography, light and electron microscopy. Titin and α-SMA protein expressions were determined by Western blot. Results The animals underwent high rate pacing on LAA for a mean of 42.23± 21.70 days before presenting AF. Electrophysiological analysis revealed that AERP completely resumed in 3-mo post AF goats. Echocardiography displayed that the size of left atrium resumed almost in 6-too post AF goats （P〈 0.01）. Pathological and electron microscopic examination revealed the disorder of myofibrils, augmentation of intercellular space, myolysis, accumulation of glycogen, and numerous bigger mitochondria among atrial cardiomyocytes in 3-mo AF goats. They recovered mostly in 6-mo post AF goats. Western blot showed that the band density oftitin significantly reduced in 3-mo AF goats compared to SR ones [1826 ± 319 vs 5012±854, P 〈 0.01]. In 3- and 6-mo post AF goats, titin increased gradually and it reversed completely in 6-mo post AF goats （3841 ± 601 and 4523 ±833 respectively, P 〈 0.01）. Conversely, the band density ofa-SMAwas significantly higher in 3-mo AF goats （5324 ± 948） than in SR ones （1619 ±271, P 〈 0.01）. In 3- and 6-mo post-AF goats, α-SMA decreased gradually, and it recovered mostly in 6- mo post AF goats （4437 ± 792 and 2205 ± 540 respectively, P〈 0.01,）. Conclusions These data indicate that the reversal of dedifferentiation of atrial cardiomyocyts is a very slow process, and it is definitely essential for normal cardiac function .

The Development of Successive Conjunctions of Chinese

The paper explored the development of successive conjunctions from Archaic Chinese to Contemporary Chinese from a macroscopic perspective.Data statistics and diachronic study method were adopted in this paper,and the results indicated that a quantity of new successive conjunctions have been produced both in Archaic Chinese and Mid-ancient Chinese,and at the same time a very large proportion of the old successive conjunctions were superseded by the new.Those which appeared in very few types of corpus and have low frequency of use are more likely to be eliminated.In Contemporary Chinese,the successive conjunction system tends to be stable and concise.

The Relationship between Financial Reporting System and Project Success: A Case of Construction Projects in UAE

The purpose of this paper is to deliver a better perception of the project success,and how reporting system might increase the probability of project success in construction projects in UAE.Further,it aims at exploring the relationship between effective reporting system in terms of the characteristic of its outputs(mainly effectiveness of financial reporting system)and project success.Semi-structured interviews with a number of interior auditors,accountants,and chief financial officers(CFOs)from different corporations in construction sector in UAE in order to recognize how effective reporting system in terms of the characteristic of its outputs(broad scope,timeliness,aggregation,and integration)might contribute to increase the probability of project success.There are several success factors in construction projects in UAE,thus it is very hard to capture all these factors in one paper.Hence,this paper is not considering all project success factors rather it focuses on the characteristic of outputs of the reporting system generally and the financial reporting system particularly(broad scope,timeliness,aggregation,and integration),as most of the studies in the literature considered the reporting system as a key factor of project success.This paper adds to both project management and accounting research by evidencing results from an exploration how effective reporting might impact the project success,with valuable implications for standard officials,customers,investors,stakeholders,sponsors,shareholders,CFOs,project developer,consultants,internal auditors,and accounting academics.The effective reporting system in United Arab Emirates(UAE)construction projects enables possessors,customers,and contractors of projects to get timely information about the progress of project in a brief and significant format which in turn improve the decision-making process and contribute to project success.This paper implies a contribution for both project management literature and accounting research by investigative the effectiveness of reporting system in project successes from historical point of view and contemporary point of view.

云南某混合型胶磷矿正-反浮选工艺技术试验研究

以云南某中低品位混合型胶磷矿为研究对象,进行了工艺矿物学和可选性研究。采用常温正反浮选工艺流程,自制水玻璃和捕收剂,通过磨矿细度试验,调整剂、捕收剂用量试验等,确定了最佳的浮选工艺和试验条件。在原矿w(P_(2)O_(5))19.56%、w(MgO)2.83%、常温条件下,采用正-反浮选工艺流程:开路实验,可得到精矿指标为w(P_(2)O_(5))28.79%、w(MgO)0.94%,精矿回收率73.44%;闭路试验,取得精矿w(P_(2)O_(5))28.87%、w(MgO)0.92%、回收率81.78%、尾矿w(P_(2)O_(5))8.13%的指标。为该矿的工业利用打下了坚实的试验基础。