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Studies on Human Dietary Requirements and Safe Range of Dietary Intakes of Selenium in China and Their Application in the Prevention of Related Endemic Diseases 被引量:14
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作者 YANG GUANG-QI AND XIA YI-MING (Department of Trace Element Nutrition, Institute of Nutrition and Food Hygiene, Chinese Academy of Preventive Medicine, Beijing 100050, China) 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 1995年第3期187-201,共15页
The human dietary selenium requirement in China has been estimated by various methods. The minimum dietary selenium requircment for the prevention of Keshan disease (KD) was found to be around 17 μg/d. On the other h... The human dietary selenium requirement in China has been estimated by various methods. The minimum dietary selenium requircment for the prevention of Keshan disease (KD) was found to be around 17 μg/d. On the other hand, an intake of 40 μg/d is required to maintain the plasma glutathione peroxidase (GPx) activity at plateau. Hence 40 μg/d is considered as the adequate dietary selenium requirement. Studies conducted in a chronic selenosis area indicate thai the toxic dietary selenlum inlake (adverse effect level), which would maintain the characteristic fingernail changes, was approximately 1600 μg/d. The mean value of dietary selenium intakes, which enabled the five patients to recover from fingernail lesions, was found to be 819 ±126μg/d. At a 95% confidence limit, the lower limit is around 600μg/d. Therefore, 600 and 400μg/d were suggested as the individual daily maximum safe selenium intake and the safe dietary selenium intake, respectively,The results were used in the prevention of Se-related endemic KD and Kashin-Beck disease (KBD) 展开更多
关键词 Studies on Human Dietary requirements and Safe Range of Dietary Intakes of Selenium in China and Their Application in the Prevention of Related Endemic Diseases
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Mass transfer mechanisms in fixed-bed adsorption of erythromycin 被引量:2
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作者 Ying SUN Jiawen ZHU +2 位作者 Kui CHEN Sheng ZHU Jie XU 《Frontiers of Chemical Science and Engineering》 SCIE EI CSCD 2008年第4期353-360,共8页
The equilibrium and kinetic characteristics of the adsorption of erythromycin to Sepabeads SP825 were determined.The equilibrium data in a batch system was well described by a Langmuir isotherm.The separation performa... The equilibrium and kinetic characteristics of the adsorption of erythromycin to Sepabeads SP825 were determined.The equilibrium data in a batch system was well described by a Langmuir isotherm.The separation performance was investigated in a fixed-bed system with respect to the adsorption superficial velocity,ionic strength and pH.A mathematical model was used to simulate the mass transfer mechanism,taking film mass transfer,pore diffusion and axial dispersion into account.The model predictions were consistent with the experi-mental data and were consequently used to determine the mass transfer coefficients. 展开更多
关键词 fixed-bed adsorption superficial velocity ionic strength erythromycin However investigations on the parameters governing the performance of this technology are still scarce.In the present work a polymeric and porous resin Sepabeads SP825 resin was used for its higher adsorption efficiency compared with the resins reported.The equilib-rium capacity of Sepabeads SP825 for EM in a batch system was established using a Langmuir isotherm.The effects of superficial velocity ionic strength and pH on the adsorption process were determined from the results of fixed bed experiments.And a model of the purification process was used to simulate the mass transfer mechanism which has taken film mass transfer pore diffusion and axial dispersion into account.The experimental adsorp-tion measurements were compared to the results calcu-lated from the model.The completion of these studies provide some essential parameters which are required in order to design a successful purification process and better understand the fundamentals of these process.
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