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Acute Coronary Syndrome of Young Subjects at the Luxembourg Mother-Child University Hospital in Bamako
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作者 Mamadou Toure Mariam Dagnogo +15 位作者 Massama Konate Mariam Sako Daouda Fofana Hamma Sankare Almou A. Diall Modibo Doumbia Baba I. Diarr Mady Sow Abdoul Wahhab Terra Coumba A. Thiam Boubacar Sonfo Boubacar Diarra Asmaou Keita Ousmane Traore Hamidou O. Ba Ichaka Menta 《World Journal of Cardiovascular Diseases》 CAS 2024年第3期157-165,共9页
Introduction: Acute coronary syndrome is often the first event of coronary disease of young subjects. Objective: To study sociodemographic, clinical, paraclinical, therapeutic and evolutionary aspects of acute coronar... Introduction: Acute coronary syndrome is often the first event of coronary disease of young subjects. Objective: To study sociodemographic, clinical, paraclinical, therapeutic and evolutionary aspects of acute coronary syndrome of young subjects. Patients and Methods: Descriptive cross-sectional study with prospective recruitment from October 01, 2020 to March 31, 2022. Were included all patients admitted for acute coronary syndrome whose age was less or equal to 45 years and who had undergone coronary angiography at the Mother-Child University Hospital on Luxembourg from Bamako. Results: During the study period, we collected 60 patient files out of 198. These 60 patient files met our inclusion criteria. Hospital frequency was 30.30%. Average age of patients was 40.43 ± 3.9 years. Sex ratio M/F was 5.3. Main cardiovascular risk factor was smoking tobacco (23.42%), followed by dyslipidemia (13.92%). Functional signs were dominated by angina 62% followed by dyspnea 25.3%. Persistent ST-segment elevation on electrocardiogram was present in 76.4%. Left ventricular systolic dysfunction was present in 26.5%. Time to first medical contact was more than 12 hours in 62.7% of cases. Radial approach was adopted in 94% of cases. Coronary angiography was pathological in 85% (n = 51) of cases. Lesions were single-vessel disease in 47.1% and culprit artery was anterior interventricular in 51% of cases. Dual anti-platelet aggregation was aspirin and ticagrelor in 91.8% of cases. Angioplasty was performed in all patients who had significant abnormalities at coronary angiography. In-hospital mortality was 3.9%. Conclusion: Acute coronary syndromes exist in young Africans with a male predominance. Main cardiovascular risk factor is smoking tobacco. Coronary lesions are single vessel disease in the majority of case. Most of patients meet medical team after 12 hours. Time to first medical contact is a main challenge in our country. 展开更多
关键词 Acute Coronary Syndrome Young subjects Coronary Angiography CHU Luxembourg BAMAKO
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Construction of enhanced multi-polarization and high performance electromagnetic wave absorption by self-growing ZnFe_(2)O_(4)on Cu_(9)S_(5)
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作者 Wenxiong Chen Honglong Xing 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第8期1922-1934,共13页
The development of 3D structural composites with electromagnetic(EM)wave absorption could attenuate EM waves.Herein,magnetized flower-like Cu_(9)S_(5)/ZnFe_(2)O_(4)composites were fabricated through a multistep hydrot... The development of 3D structural composites with electromagnetic(EM)wave absorption could attenuate EM waves.Herein,magnetized flower-like Cu_(9)S_(5)/ZnFe_(2)O_(4)composites were fabricated through a multistep hydrothermal method.The crystallographic and surface phase chemical information,morphological structure,and magnetic and EM parameters of the composites were analyzed.The prepared Cu_(9)S_(5)/ZnFe_(2)O_(4)composites have multiple loss paths for EM waves and present an overall 3D flower-like structure.The Cu_(9)S_(5)/ZnFe_(2)O_(4)composites exhibit a minimum reflection loss of-54.38 dB and a broad effective absorption bandwidth of 5.92 GHz.Through magnetization,ZnFe_(2)O_(4)particles are self-assembled and grown on the surfaces of Cu_(9)S_(5).Such a modification is conducive to the generation of additional cross-linking contact sites and the effective introduction of a large number of phase interfaces,crystalline defects,special three-dimensional flower-like structures,and magneto-electrical coupling loss effects.Moreover,the synergistic effect of multiple loss strategies effectively improves EM wave absorption by the material.This work can provide a strategy for the use of magnetizationmodified sulfide composite functional materials in EM wave absorption. 展开更多
关键词 self-assembled material electromagnetic wave absorption enhanced multi-polarization effect Cu_(9)S_(5)/ZnFe_(2)O_(4)composites radar cross-section
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The Reasons for Admission of Elderly Subjects in Intensive Care at the CHU Ignace Deen
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作者 Abdoulaye Touré Amadou Yalla Camara +2 位作者 Almamy Bangoura Donamou Joseph M’mah Lamine Camara 《Open Journal of Emergency Medicine》 2023年第3期100-109,共10页
Objective: To determine the reasons for admission of elderly subjects and the prognosis in general intensive care. Patients and Methods: Observational descriptive and analytical study with prospective collection of da... Objective: To determine the reasons for admission of elderly subjects and the prognosis in general intensive care. Patients and Methods: Observational descriptive and analytical study with prospective collection of data over a period of one year from January 1 to December 31, 2021. Patients aged 65 or over were included. Abstract: During the study period, 223 cases were collected out of 587 patients admitted, giving a prevalence of 37.9%. The average age was 74.127.39 ± years with extremes of 65 and 96 years and a male predominance (58.7%). The comorbidities were dominated by arterial hypertension (71.3%). The patients were: transferred from medical and surgical emergencies (75.8%). The average admission time was 48.8 ± 29.8 hours. One hundred and eight patients had a Glasgow score between 3 and 7. The reasons for admission were dominated by vascular causes (51.6%). Strokes of any type accounted for 43.9% of these reasons for admission. The average time for carrying out the biological assessments and imaging was 41.8 ± 27.3 hours with the extremes of 3 and 89 hours, 37.2% had a complete assessment within 24 hours. The average duration of hospitalization was 7.10 ± 8.87 days with extremes of 1 and 72 days. The mortality rate was 71.7%. Conclusion: This study has made it possible to take stock of the reasons for the admission of elderly subjects to intensive care. It appears that vascular causes are the main reasons for admission with heavy comorbidities which results in high mortality. 展开更多
关键词 Reasons for Admission Elderly subject RESUSCITATION
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Achieve Intended Learning Outcomes and Improving Digital Literacy Skills for Practical-Based Subjects Using Online Teaching via Propagation of OER Materials
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作者 Ka Man Mok Prabrisha Sarkar +3 位作者 Shui Wing Ng Sumit Mandal Qing Chen Manas Kumar Sarkar 《Journal of Textile Science and Technology》 2023年第1期84-100,共17页
As professors are subjected to teaching their classes online due to the recent COVID-19, our local Hong Kong students find it difficult to consult their teachers, and ultimately would fail to achieve the intended lear... As professors are subjected to teaching their classes online due to the recent COVID-19, our local Hong Kong students find it difficult to consult their teachers, and ultimately would fail to achieve the intended learning outcomes, especially for practical-based subjects. In this research, students having online classes of a practical-based fabric design subject were encouraged to self-study from Open Educational Resource (OER) materials for a further and better understanding of their subject. Additionally, online materials were developed to improve students’ understanding via skill of digital literacy. Their learning progress was evaluated and compared to the face-to-face version. The majority of students found online classes combined with self-studying OER materials, potentially be a substitute for face-to-face classes. Most of the students further opined different OER videos assisted them without any face-to-face instructions in practical works, to develop new fabric samples from the inspiration. Analysis of test results, and comparison of students’ final grades with different learning modes, supported these phenomena. 展开更多
关键词 Online Teaching Open Educational Resources Learning Outcome Fabric Design Textile Education Teaching Design subjects
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Exploring the Dual Subjectivity of Kindergarten's Self-made Play and Teaching Aids Activities from the Perspective of Children's Play Development in China 被引量:1
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作者 Yuwei Zhao 《教育技术与创新》 2024年第1期1-9,共9页
The joint development of teachers and young children is the basis for promoting the development of high-quality preschool education in the new era,and encouraging early childhood teachers to make playthings according ... The joint development of teachers and young children is the basis for promoting the development of high-quality preschool education in the new era,and encouraging early childhood teachers to make playthings according to local conditions is both the fine tradition of China's early childhood education and the direct orientation of China's preschool education policy.Homemade play and teaching aids are some of the methods often used in kindergartens,which skillfully combine young children's daily life objects with toys and early childhood teaching,not only enriching the collective activities of young children but also cultivating children's abilities in various aspects.Kindergarten homemade"play and teaching aids"for early childhood teachers and children have their special educational significance and value,therefore,this paper is based on the children and teachers double subject basis,discussing the homemade"play and teaching aids"for children and teachers of the double subject meanings,and puts forward the realization of the This paper discusses the double-subjective meaning of homemade teaching aids for children and teachers on the basis of the double-subjective foundation of children and teachers,and puts forward specific suggestions for realizing the double-subjectivity of kindergarten homemade teaching aids to enrich the theoretical value and practical significance of homemade teaching aids,to provide theoretical references and support for the relevant staff. 展开更多
关键词 Self-made playthings Double subjectivity KINDERGARTEN China
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New Moral Subjects: Walking the Line Between Autonomy and Automaton
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作者 Ralf Lüfter 《Journal of Philosophy Study》 2023年第11期463-467,共5页
The question of“new moral subjects”arises today in connection with the use of advanced technologies in the context of Industry 4.0,i.e.,the industrial enterprise investing in smart factories,co-robotic,additive manu... The question of“new moral subjects”arises today in connection with the use of advanced technologies in the context of Industry 4.0,i.e.,the industrial enterprise investing in smart factories,co-robotic,additive manufacturing,augmented reality,cyber security,big data,etc.Industry 4.0 underpins what is being heralded as Industry 5.0.Technologies in this field excel in that they are not used for the mere execution of processes designed,programmed,and controlled by man,but are applied to realise“autonomously”goals in the industrial context.Consequently,their degree of automation is no longer defined by increasing independence from human beings,but by the ability to spontaneously initiate a process and implement it to useful effect.The comparison between man and machine,and the justification for the introduction of“new moral subjects”thus crucially depend on the location of“moral being”in the reference to their“autonomy”as a property characterising the“subject man”,but not the exclusive prerogative of the latter. 展开更多
关键词 new moral subjects ethics of automation RESPONSIBILITY AUTONOMY Industry 4.0
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Relationship Between Individuals’Epidemic Risk Perception Within Living Space and Subjective Well-Being:Empirical Evidence from China after the First Wave of COVID-19
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作者 SONG Jiangyu ZHOU Suhong +1 位作者 KWAN Mei-Po ZHENG Zhong 《Chinese Geographical Science》 SCIE CSCD 2024年第2期369-382,共14页
It is common to observe the epidemic risk perception(ERP)and a decline in subjective well-being(SWB)in the context of public health events,such as Corona Virus Disease 2019(COVID-19).However,there have been few studie... It is common to observe the epidemic risk perception(ERP)and a decline in subjective well-being(SWB)in the context of public health events,such as Corona Virus Disease 2019(COVID-19).However,there have been few studies exploring the impact of individuals’ERP within living space on their SWB,especially from a geographical and daily activity perspective after the resumption of work and other activities following a wave of the pandemic.In this paper,we conducted a study with 789 participants in urban China,measuring their ERP within living space and examining its influence on their SWB using path analysis.The results indicated that individuals’ERP within their living space had a significant negative effect on their SWB.The density of certain types of facilities within their living space,such as bus stops,subway stations,restaurants,fast food shops,convenience shops,hospitals,and public toilets,had a significantly negative impact on their SWB,mediated by their ERP within living space.Additionally,participation in out-of-home work and other activities not only increased individuals’ERP within living space,but also strengthened its negative effect on their SWB. 展开更多
关键词 subjective well-being epidemic risk perception living space the density of facilities out-of-home activities
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The Effects of Childhood Trauma on College Students’Depressive Symptoms:The Mediation Role of Subjective Well-Being and the Moderation Role of Resilience
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作者 Fuhua Yang Jiaci Lin +3 位作者 Rong Chen Chunlin Gao Maoying Cui Keli Yin 《International Journal of Mental Health Promotion》 2024年第9期757-766,共10页
Background:The enduring and detrimental impact of childhood trauma on later health and well-being is now well established.However,research on the relationship between childhood trauma and depressive symptoms,along wit... Background:The enduring and detrimental impact of childhood trauma on later health and well-being is now well established.However,research on the relationship between childhood trauma and depressive symptoms,along with the potential risk and protective factors,is insufficient in the context of Chinese college student population.Methods:Data on childhood trauma,depressive symptoms,resilience,and subjective well-being were collected through surveys conducted with 367 Chinese university students.The data collected in this study were analyzed using SPSS 26.0 and PROCESS 3.5.Results:The results revealed that subjective well-being mediated the relationship between childhood trauma and depressive symptoms among college students,with direct and indirect effects accounting for 59.46%and 40.54%of the total effect,respectively.The pathway process between subjective well-being and depressive symptoms was moderated by resilience,whereby an increase in resilience levels corresponded to a gradual escalation in the predictive power of subjective well-being on depressive symptoms.Conclusion:The study indicates that childhood trauma significantly and positively predicts depressive symptoms among college students,and it can also directly predict depressive symptoms through the mediating effect of subjective well-being.Elevating levels of psychological resilience and subjective well-being among college students can mitigate depression and promote psychological well-being.From the perspective of positive psychology,the present study provides a new perspective for the prevention and intervention of depressive symptoms among college students. 展开更多
关键词 Childhood trauma depressive symptoms subjective well-being RESILIENCE
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The Entanglement of Thing and Subject in Virginia Woolf’s“Street Haunting:A London Adventure”
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作者 QIU Lin 《Journal of Literature and Art Studies》 2024年第8期669-678,共10页
Virginia Woolf’s essay“Street Haunting:A London Adventure”highlights the complex relationships between things and the subject.On the individual’s level,indoor things construct and limit the subject’s identity,whi... Virginia Woolf’s essay“Street Haunting:A London Adventure”highlights the complex relationships between things and the subject.On the individual’s level,indoor things construct and limit the subject’s identity,while outdoor things allow fluid identities;these things reveal Woolf’s dual identity as both a rebel against and a ruler of the hierarchical system.On the intersubjective level,subjects are linked through common aesthetic experience mediated by things,which enjoys a high degree of arbitrariness.With the help of things,subjects form an“imagined community”.Concerning the relationship between things and the mind,things also endow order in the fragmented reality,yet in this sense they are abstract,metaphysical and universal rather than specific in Virginia Woolf’s thoughts.They are the withdrawn things expressed by sensual qualities.These sensual aspects,however,are tools to reveal the essence and meaning of life,secondary to the mind. 展开更多
关键词 THING subject identity community MIND
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Operation optimization strategy of existing residential building energy-saving renovation market:From the perspective of subject behavior
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作者 GUO Han-ding LI Rui-jiao +1 位作者 QIN Guang-lei ZHANG Yin-xian 《Ecological Economy》 2024年第3期290-300,共11页
The energy-saving renovation of existing residential buildings is a crucial measure to achieve the strategic goal of energy conservation and emission reduction in China and build ecologically livable cities.This artic... The energy-saving renovation of existing residential buildings is a crucial measure to achieve the strategic goal of energy conservation and emission reduction in China and build ecologically livable cities.This article focuses on the perspective of subject behavior,starting from analyzing the current situation and difficulties of the operation of the energy-saving renovation market for existing residential buildings in China,drawing on the practical experience of the operation of the existing residential building energy-saving renovation market abroad.Based on principles such as systematicity,humanization,feasibility,and sustainability,the article constructs an operation optimization system of the existing residential building energy-saving renovation market from the perspective of subject behavior.In order to provide a reference for the healthy and orderly operation of the existing residential building energy-saving renovation market,this paper proposes implementation strategies for optimizing the operation of the existing residential building energy-saving renovation market.Suggestions are proposed from four aspects:optimizing the market environment,innovating the financing model,building the information sharing platform,and utilizing the synergies of the main subjects. 展开更多
关键词 the existing residential buildings energy-saving renovation market operation optimization strategy perspective of subject behavior
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From the Subjectivity of Human Rights to the Universality of Human Rights——A Preliminary Interpretation of the Theory on the Subjectivity of Human Rights
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作者 HUANG Jinrong 《The Journal of Human Rights》 2024年第3期709-733,共25页
Universality is one of the essential characteristics of human rights, but there is a substantive difference between idealism and realism in understanding the concept of universality of human rights. The concepts of ra... Universality is one of the essential characteristics of human rights, but there is a substantive difference between idealism and realism in understanding the concept of universality of human rights. The concepts of radical universality and strong universality based on the concept of natural human rights are too idealistic and thus have a high risk of being alienated into a tool of international re-pression in practice. On the contrary, the theory on the subjectivity of human rights can effectively defuse this risk brought about by radical universality and strong universality. Advocating a transition from the universality of human rights to the subjectivity of human rights not only keeps in line with the actual construction process of international human rights, but can also effectively interpret the practical difficul-ties in the realization process of international human rights. Therefore, it can be used as another alternative theory on human rights beyond the theory of natural human rights. 展开更多
关键词 human rights UNIVERSALITY subjectIVITY concept of natural human rights
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Michel Serres and Posthuman Subjectivities:Silencing and Trans-lation to Explore Co-implications
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作者 Orsola Rignani 《Philosophy Study》 2024年第5期246-255,共10页
The contribution aims to examine the co-implications between Serres’work and posthumanist ideas of body and subjectivity.This scope is pursued primarily through the methodological choice of a gerund,such as silencing... The contribution aims to examine the co-implications between Serres’work and posthumanist ideas of body and subjectivity.This scope is pursued primarily through the methodological choice of a gerund,such as silencing,and the harnessing of its performative,processual,and relational value.Building on Serres’conception of silence as a dilation of the me the paper will follow Serresian anti-Cartesian reflections on the interchangeability of subject and object,his conception of the pre-positional body,and his thematization of the soul-body relationship.In close inter-implication with the employment of silencing is then the choice,again as a methodological device,of the preposition trans,made to act in order to explore the affinities/overlaps/assonances between Serres’theorization of the body,dimension of the human,and posthumanist conceptions of body/subjectivity. 展开更多
关键词 posthuman subjectivity Michel Serres SILENCING translation co-implications
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A Novel Method for Cross-Subject Human Activity Recognition with Wearable Sensors
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作者 Qi Zhang Feng Jiang +4 位作者 Xun Wang Jinnan Duan Xiulai Wang Ningling Ma Yutao Zhang 《Journal of Sensor Technology》 2024年第2期17-34,共18页
Human Activity Recognition (HAR) is an important way for lower limb exoskeleton robots to implement human-computer collaboration with users. Most of the existing methods in this field focus on a simple scenario recogn... Human Activity Recognition (HAR) is an important way for lower limb exoskeleton robots to implement human-computer collaboration with users. Most of the existing methods in this field focus on a simple scenario recognizing activities for specific users, which does not consider the individual differences among users and cannot adapt to new users. In order to improve the generalization ability of HAR model, this paper proposes a novel method that combines the theories in transfer learning and active learning to mitigate the cross-subject issue, so that it can enable lower limb exoskeleton robots being used in more complex scenarios. First, a neural network based on convolutional neural networks (CNN) is designed, which can extract temporal and spatial features from sensor signals collected from different parts of human body. It can recognize human activities with high accuracy after trained by labeled data. Second, in order to improve the cross-subject adaptation ability of the pre-trained model, we design a cross-subject HAR algorithm based on sparse interrogation and label propagation. Through leave-one-subject-out validation on two widely-used public datasets with existing methods, our method achieves average accuracies of 91.77% on DSAD and 80.97% on PAMAP2, respectively. The experimental results demonstrate the potential of implementing cross-subject HAR for lower limb exoskeleton robots. 展开更多
关键词 Human Activity Recognition Cross-subject Adaptation Semi-Supervised Learning Wearable Sensors
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The internal COF features in Dome A of Antarctica revealed by multi-polarization-plane RES 被引量:5
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作者 王帮兵 田钢 +1 位作者 崔祥斌 张向培 《Applied Geophysics》 SCIE CSCD 2008年第3期230-237,共8页
The ice exceeding one million years old has significant meaning for verifying and interpreting the middle Pleistocene transition (MPT) and the relationship between greenhouse gas and climate change. The region near ... The ice exceeding one million years old has significant meaning for verifying and interpreting the middle Pleistocene transition (MPT) and the relationship between greenhouse gas and climate change. The region near Dome A in Antarctica satisfies the conditions for obtaining million-years-old ice since it has low temperatures and low accumulation rates. We analyze the corresponding relation between radar wave features and the crystal orientation fabric (COF) types based on the results of multi-polarization plane radio echo sounding (RES). The results show that, even in the summit of the ice sheet, the COF type is not perfect, but is an elongated single-pole COF. Principal-axis-orientation differences of the COF among the different periods exist and reveal that the ice flow orientations are not constant but deviate clockwise with the increasing depth. This may be related to the adjacent basal valley or both height and position changes of the summit during the glacial-interglacial periods. 展开更多
关键词 Crystal orientation fabric (COF) radio echo sounding (RES) multi-polarization plane technique ice flow orientation
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教材心理化? 杜威作品中译本对“subject matter”的误译及其影响
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作者 丁道勇 《北京大学教育评论》 CSSCI 北大核心 2023年第4期85-109,188,共26页
把subject matter译作“教材”,使之对等于教学过程中使用的包括教科书在内的各类教学材料,是杜威作品中译本中反复出现的一个译法。通过对杜威作品的中、英文本进行相关比对,可知这是一个误译。在杜威作品中,subject matter指的是“学... 把subject matter译作“教材”,使之对等于教学过程中使用的包括教科书在内的各类教学材料,是杜威作品中译本中反复出现的一个译法。通过对杜威作品的中、英文本进行相关比对,可知这是一个误译。在杜威作品中,subject matter指的是“学科内容”,是各门学科提供的事实和法则,不是教学过程中使用的教科书等教材。“教材心理化”这个中文表达,是subject matter误译的一个直接结果。对这一中文表达的内涵与影响的考察,进一步印证了上述研究发现。Subject matter是杜威反复提及的一个概念,是联系其教育哲学与哲学重建工作的关键词。对subject matter的误译,造成了有关杜威理论的一系列误解。 展开更多
关键词 subject matter 教材 教材心理化 杜威
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基于语料库的SUBJECT TO,PURSUANT TO,IN ACCORDANCE WITH语义韵对比研究
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作者 周政权 赵增巽 《文化创新比较研究》 2023年第29期180-185,共6页
合同文本中,subject to、pursuant to、in accordance with常用作同义/近义词表达当事人行事之依据,多被翻译成“根据”,但实际上三者的搭配和使用语境大有差异。该文在自建合同语料库的基础上,以数据驱动的研究方法,以三者为节点词,考... 合同文本中,subject to、pursuant to、in accordance with常用作同义/近义词表达当事人行事之依据,多被翻译成“根据”,但实际上三者的搭配和使用语境大有差异。该文在自建合同语料库的基础上,以数据驱动的研究方法,以三者为节点词,考察其搭配行为、语义倾向和语义韵。研究发现,三者虽为近义词,但实际使用中搭配、语义倾向和语义韵均存在明显差异:subject to多与权力授权、行为约束类语义范畴词语搭配,积极、中性和消极语义韵俱全,以中性居多,但与消极涵义搭配词共现的频数显著高于其他两词;pursuant to多与“具体条款+编号”搭配,in accordance with较多与法规、规则规范类词语搭配,二者都表现出极低的消极语义韵,前者带有一定的积极语义韵强度,后者中性语义韵占绝对地位。 展开更多
关键词 合同 语义韵 语义倾向 subject to pursuant to in accordance with
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Gastroprotection induced by capsaicin in healthy human subjects 被引量:10
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作者 Gyula Mózsik János Szolcsányi István Rácz 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第33期5180-5184,共5页
AIM: To evaluate the gastro-protective effect of capsaicin against the ethanol- and indomethacin (IND)-induced gastric mucosal damage in healthy human subjects. METHODS: The effects of small doses (1-8 μg/mL, 10... AIM: To evaluate the gastro-protective effect of capsaicin against the ethanol- and indomethacin (IND)-induced gastric mucosal damage in healthy human subjects. METHODS: The effects of small doses (1-8 μg/mL, 100 mL) of capsaicin on the gastric acid secretion basal acid output (BAO) and its electrolyte concentration, gastric transmucosal potential difference (GTPD), ethanol- (5 mL 300 mL/L i.g.) and IND- (3×25 mg/d) induced gastric mucosal damage were tested in a randomized, prospective study of 84 healthy human subjects. The possible role of desensitization of capsaicin-sensitive afferents was tested by repeated exposures and during a prolonged treatment. RESULTS: Intragastric application of capsaicin decreased the BAO and enhanced “non-parietal” component, GTPD in a dose-dependent manner. The decrease of GTPD evoked by ethanol was inhibited by the capsaicin application, which was reproducible. Gastric microbleeding induced by IND was inhibited by co-administration with capsaicin, but was not influenced by two weeks pretreatment with a daily capsaicin dose of 3×400μg i.g. CONCLUSION: Capsaicin in low concentration range protects against gastric injuries induced by ethanol or IND, which is attributed to stimulation of the sensory nerve endings. 展开更多
关键词 CAPSAICIN ETHANOL INDOMETHACIN Gastric transmucosal potential difference Gastric microbleeding GASTROPROTECTION Healthy human subjects
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Age related changes of the central lamina cribrosa thickness, depth and prelaminar tissue in healthy Chinese subjects 被引量:1
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作者 Hui Xiao Xiao-Yu Xu +1 位作者 Yi-Min Zhong Xing Liu 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2018年第11期1842-1847,共6页
AIM: To investigate the variation in the central lamina cribrosa thickness(cLCT), and the central anterior lamina cribrosa surface depth(cALCSD), as well as the central prelaminar tissue thickness(cPLTT) relate... AIM: To investigate the variation in the central lamina cribrosa thickness(cLCT), and the central anterior lamina cribrosa surface depth(cALCSD), as well as the central prelaminar tissue thickness(cPLTT) related to age in healthy Chinese subjects.METHODS: A total of 96 eyes from 96 Chinese healthy subjects were recruited. According to age, the 96 cases were divided into three groups: the young group(YG, 18-39 y), middle-age group(MG, 40-59 y) and older-age group(OG, 60 y and above). Lamina cribrosa images were obtained from all participants using radial linear protocol by enhanced depth imaging spectral-domain optical coherence tomography. The cLCT, cALCSD and cPLTT were calculated from the average value of the lamina cribrosa thickness, anterior lamina cribrosa surface depth and prelaminar tissue thickness in the optic nerve head(ONH) centre point and paracentral points(150 μm from the centre point in the horizontal and vertical directions). RESULTS: For the total subjects, the mean cLCT, c ALCSD and cPLTT were 235.18±41.27, 358.02±93.80 and 182.02±92.11 μm, respectively. No statistically significant differences in cLCT, cALCSD or cPLTT were found between gender and different eyes(P=0.27-0.92). The cLCT of the OG was the thickest among the three groups, while the c PLTT of the YG was the thickest among the three groups(P〈0.05). Age was positively correlated with cLCT(r=0.42, P〈0.001), and negatively correlated with cPLTT(r=-0.24, P=0.02). No significant correlation was found between the age and cALCSD(r=-0.06, P=0.55). And no correlation has been found between axial length and cLCT, cALCSD and c PLTT(P=0.11-0.81).CONCLUSION: The impact of age on the cLCT and the cPLLTT should be taken into account when analysing glaucoma and other diseases related to lamina cribrosa. 展开更多
关键词 lamina cribrosa thickness normal subjects optical coherence tomography age
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Fractal analysis of retinal vasculature in normal subjects on ultra-wide field fluorescein angiography 被引量:3
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作者 Wen-Ying Fan Alan Fleming +6 位作者 Gavin Robertson Akihito Uji Jano van Hemert Michael Singer Min Sagong Michael Ip SriniVas R.Sadda 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2020年第7期1109-1114,共6页
AIM: To evaluate the fractal feature of the retinal vasculature of normal eyes on a stereographic projected and montaged ultra-wide field(UWF) fluorescein angiography(FA).METHODS: Prospective, observational, cross-sec... AIM: To evaluate the fractal feature of the retinal vasculature of normal eyes on a stereographic projected and montaged ultra-wide field(UWF) fluorescein angiography(FA).METHODS: Prospective, observational, cross-sectional study. Totally 59 eyes of 31 normal subjects were imaged using the Optos 200 Tx. Images obtained at different gaze angles stereographically projected and montaged. The early-phase UWF FA frames were processed to segment the retinal vasculature and the results were exported as binary masks. The fractal dimension(FD) was calculated using the box-counting method.RESULTS: The global FD for the entire retina was 1.6±0.04, with no difference between males and females(1.59±0.04 vs 1.61±0.04, P=0.084) or between right and left eyes(1.6±0.04 vs 1.6±0.05, P=0.61). FD was nonuniformly distributed among four quadrants(P<0.001) and decreased as the distance from the fovea increased(P<0.001). A negative association was observed between FD and age(R=-0.37, P=0.006), and this relationship was observed in the posterior and mid-peripheral retina(P<0.05) but absent in far-periphery(P>0.05).CONCLUSION: Fractal geometry is non-uniformly distributed across the retina in normal eyes and decreases from the fovea to the far-periphery. Subjects with an older age tend to have a smaller FD, however, the FD in the farperiphery does not appear to be influenced by age. 展开更多
关键词 fractal analysis RETINA ultra-wide field fluorescein angiography normal subject
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Morphometric Analysis of the Brain Ventricles in Normal Subjects Using Computerized Tomography 被引量:1
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作者 Moawia Gameraddin Abdalrahim Alsayed +1 位作者 Amir Ali Mosleh Al-Raddadi 《Open Journal of Radiology》 2015年第1期13-19,共7页
Background and Aim: As ageing advances, the human brain undergoes many gross and histopathological changes with regression of the brain tissue leading to the enlargement of the ventricles. Knowledge of morphometric an... Background and Aim: As ageing advances, the human brain undergoes many gross and histopathological changes with regression of the brain tissue leading to the enlargement of the ventricles. Knowledge of morphometric and size of normal ventricular system of brain is important to understand these changes. Methods: For the present perspective study, computerized tomography (CT) for 152 patients (Male-89 and Females-63) were studied for the measurements of fourth ventricle, third ventricle and lateral ventricle and it was statistically analyzed. Results: The anteroposterior extent of the body of the lateral ventricles on the right side was 74.89 + 9.86 mm and 70.06 + 8.83 mm in the males and females and on the left side was 74.89 + 9.89 mm and 69.56 + 11.42 mm in the males and females;the length of the frontal horns on the right side was 28.53 + 3.88 mm and 26.16 + 4.21 mm in the males and females and on the left side was 28.53 + 3.88mm and 26.17 + 4.237 mm in the males and females respectively. The width and height of the fourth ventricle were 12.54 + 1.90 mm and 9.66 + 2.12 in the males and 11.60 + 2.099 mm and 9.70 + 2.219 in the females respectively. The width of the third ventricle was 5.70 + 1.54 mm and 5.40 + 1.68 mm in the males and females respectively. Conclusion: The present study has defined the morphometric measurements of the lateral ventricles, third ventricle, and fourth ventricle of the brain which has clinical correlations in diagnosis and for further line of treatment. 展开更多
关键词 BRAIN MORPHOMETRY VENTRICULAR System Size subjects TOMOGRAPHY
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