Subsequent total joint arthroplasty: Are we learning from the first stage?

BACKGROUND With the increasing incidence of total joint arthroplasty(TJA),there is a desire to reduce peri-operative complications and resource utilization.As degenerative conditions progress in multiple joints,many patients undergo multiple proce-dures.AIM To determine if both physicians and patients learn from the patient’s initial arth-roplasty,resulting in improved outcomes following the second procedure.METHODS The institutional database was retrospectively queried for primary total hip arth-roplasty(THA)and total knee arthroplasty(TKA).Patients with only unilateral THA or TKA,and patients undergoing same-day bilateral TJA,were excluded.Patient demographics,comorbidities,and implant sizes were collected at the time of each procedure and patients were stratified by first vs second surgery.Outcome metrics evaluated included operative time,length of stay(LOS),disposition,90-d readmissions and emergency department(ED)visits.RESULTS A total of 642 patients,including 364 undergoing staged bilateral TKA and 278 undergoing bilateral THA,were analyzed.There was no significant difference in demographics or comorbidities between the first and second procedure,which were separated by a mean of 285 d.For THA and TKA,LOS was significantly less for the second surgery,with 66%of patients having a shorter hospitalization(P<0.001).THA patients had significantly decreased operative time only when the same sized implant was utilized(P=0.025).The vast majority(93.3%)of patients were discharged to the same type of location following their second surgery.However,when a change in disposition was present from the first surgery,patients were significantly more likely to be discharged to home after the second procedure(P=0.033).There was no difference between procedures for post-operative readmissions(P=0.438)or ED visits(P=0.915).CONCLUSION After gaining valuable experience recovering from the initial surgery,a patient’s perioperative outcomes are improved for their second TJA.This may be the result of increased confidence and decreased anxiety,and it supports the theory that enhanced patient education pre-operatively may improve outcomes.For the surgical team,the second procedure of a staged THA is more efficient,although this finding did not hold for TKA.

Adaptive subsequence adjustment with evolutionary asymmetric path-relinking for TDRSS scheduling

Due to the limited transmission resources for data relay in the tracking and data relay satellite system （TDRSS）, there are many job requirements in busy days which will be discarded in the conventional job scheduling model. Therefore, the improvement of scheduling efficiency in the TDRSS can not only help to increase the resource utilities, but also to reduce the scheduling failure ratio. A model of nonhomogeneous parallel machines scheduling problems with time window （NPM-TW） is firstly built up for the TDRSS, considering the distinct features of the variable preparation time and the nonhomogeneous transmission rates for different types of antennas on each tracking and data relay satellite （TDRS）. Then, an adaptive subsequence adjustment （ASA） framework with evolutionary asymmetric path-relinking （EvAPR） is proposed to solve this problem, in which an asymmetric progressive crossover operation is involved to overcome the local optima by the conventional job inserting methods. The numerical results show that, compared with the classical greedy randomized adaptive search procedure （GRASP） algorithm, the scheduling failure ratio of jobs can be reduced over 11% on average by the proposed ASA with EvAPR.

Functional sample path properties of subsequence's C-R increments for a Wiener process in Hlder norm

In this paper, with the aid of large deviation formulas established in strong topology of functional space generated by HSlder norm, we discuss the functional sample path properties of subsequence＇s C-R increments for a Wiener process in HSlder norm. The obtained results, generalize the corresponding results of Chen and the classic Strassen＇s law of iterated logarithm for a Wiener process.

Research of Detection Algorithm for Time Series Abnormal Subsequence

The recent advancements in sensor technology have made it possible to collect enormous amounts of data in real time.How to find out unusual pattern from time series data plays a very important role in data mining.In this paper,we focus on the abnormal subsequence detection.The original definition of discord subsequences is defective for some kind of time series,in this paper we give a more robust definition which is based on the k nearest neighbors.We also donate a novel method for time series representation,it has better performance than traditional methods(like PAA/SAX)to represent the characteristic of some special time series.To speed up the process of abnormal subsequence detection,we used the clustering method to optimize the outer loop ordering and early abandon subsequence which is impossible to be abnormal.The experiment results validate that the algorithm is correct and has a high efficiency.

Development of 3D bicontinuous metal-intermetallic composites through subsequent alloying process after liquid metal dealloying

This study presents a novel process for the fabrication of metal-intermetallic composites with a 3D bicontinuous structure, achieved through a combination of liquid metal dealloying(LMD) and subsequent alloying. Initially, porous Ti structures are produced using the LMD process, followed by immersion in a molten Mg-3Al(wt%) metal. Due to the higher thermodynamic miscibility of Al with Ti compared to Mg, the concentration of Al in the Ti matrix increases as the immersion time increases. This results in a sequential phase transition within the Ti matrix: α-Ti → Ti_(3)Al → Ti Al. The phase transition considerably affects the hardness and strength of the composite material,with the Mg-Ti_(3)Al-Ti Al composite exhibiting a maximum hardness nearly twice as high as that of the conventional Mg-Ti composite. This innovative process holds potential for the development of various bicontinuous metal-intermetallic composites.

元坝地区千佛崖组二段页岩层序与储层特征分析

川东北元坝地区千佛崖组二段半深湖相页岩具有良好的页岩油气勘探前景。通过层序划分,对页岩岩相发育特征进行研究,对不同页岩岩相控制下的储层特征进行分析,明确准层序格架下不同页岩岩相的成因及对储层发育的影响。研究结果表明:千佛崖组二段可划分为7个准层序,根据准层序内的沉积特征,可将准层序划分为湖侵旋回为主型、湖退旋回为主型和均衡型3种不同的沉积模式。千佛崖组二段页岩发育有纹层状页岩相、层状页岩相和块状页岩相三种主要岩相类型,纹层状页岩相整体孔隙更发育,连通性更好,储集物性更好;层状页岩相整体孔隙发育程度和储集物性较纹层状页岩相次之;块状页岩相孔隙发育情况不佳,连通性一般,物性较差。页岩储层受岩相影响呈现出不同的特征,页岩岩相的纵向演化明显受准层序的控制,不同准层序类型的页岩岩相发育特征存在明显差异。整体来看,优质储层在最大洪泛面附近更为发育,优质页岩储层主要发育在湖侵旋回为主型准层序的中上部,有机质富集、孔隙发育且连通性好,是下一步勘探的有利目标;湖退旋回为主型准层序的中下部发育次优储层。

一种抑制后续换相失败的电流偏差控制参数整定方法

电网换相换流器型高压直流输电(line commutated converter-based high voltage direct current,LCC-HVDC)系统若发生后续换相失败,将严重影响交直流混联电网的安全稳定运行。文中首先针对LCC-HVDC系统故障恢复过程中电流偏差控制作用阶段易再次发生换相失败的问题,对电流偏差控制参数与换相失败之间的关系进行理论分析,发现此阶段系统若不发生换相失败,逆变侧LCC直流电压和交流换相电压须满足一定的约束关系,且该约束关系受电流偏差控制参数的直接影响。然后,基于理论分析结果,提出一种电流偏差控制参数整定方法,可改善系统故障恢复过程中对直流电压恢复速度和程度的控制要求,使系统更易满足直流电压与交流换相电压稳定运行约束关系,以降低后续换相失败概率。最后,利用PSCAD/EMTDC仿真平台CIGRE标准测试模型验证了理论分析的正确性以及参数整定方法的有效性。

奖励式众筹的后续市场效应:基于场景视角的研究

场景化赋予奖励式众筹独特的情感体验与社群价值,使得国内的众筹模式逐渐脱离早期单一的融资属性,向新品推广、品牌孵化、场景营销等多元化功能演变。文章选取小米有品众筹平台数据作为研究样本,基于场景视角探讨了奖励式众筹的场景化运作与价值创造逻辑,通过有序Logistic模型考察了奖励式众筹的后续市场效应,以及场景营销、场景互动的调节作用。研究发现,奖励式众筹绩效对于产品后续市场表现具有显著的正向影响,场景营销能够强化这一关系,而普通用户互动比领先用户互动的调节作用更为显著。异质性分析发现,奖励式众筹的后续市场效应在平台嵌入程度较高的企业中更为显著。进一步研究发现,奖励式众筹具有品牌推广效应,能够显著提升企业的品牌关注度。文章基于场景视角拓展了众筹研究的边界,对奖励式众筹平台及企业的场景化创新具有一定的指导意义。

基于生态补偿的南水北调后续工程水价研究

制定科学合理的跨流域调水工程水价是开展水源区生态补偿的重要途径之一。在现有水价的基础上,新增生态补偿作为水价的重要组成部分,运用机会成本法测算南水北调东线工程水源区生态补偿标准,并引入社会发展阶段系数和政府支付能力系数对其进行修正,构建计入生态补偿的南水北调后续工程水价定价模型。以南水北调东线一期工程胶东干线为例,得到2016、2020年水源区的理论生态补偿标准分别为116.121、199.992亿元,在现行价格基础上水价需分别提高0.93、4.51元/m^(3)。结果表明,生态补偿会耗费大量资金,只有当工程调水能力达到规划设计规模时,持续性调水才能逐步降低供水成本,否则水价会超出受水区的承受范围,工程效益也难以发挥。

担保型以物抵债协议真要识契——对《<民法典>合同编通则部分司法解释》第28条的再思考

《合同编通则司法解释》否定担保型以物抵债协议的独立地位,协调了《担保制度司法解释》第68条与《民间借贷司法解释》第23条的关系,其采取的“完成财产权利所有权变动公示的属于让与担保、未完成财产权利所有权变动公示的仅能就其受偿”做法虽大体合理,但却忽视了履约期满前签订的以物抵债协议中“为清偿而给付”情形的剔除以及存在多个未完成财产权利所有权变动公示的担保型以物抵债法律关系时各个债权人的受偿规则建构。出于尊重真实意思表示、细化操作规则的考虑,有必要重新厘定担保型以物抵债协议的概念范围、完善未完成财产权利所有权变动公示的担保型以物抵债协议中的受偿规则。

股权众筹企业后续融资绩效的影响因素研究

股权众筹是一种新型的融资模式,具有门槛低、效率高、成本低等优势,为中小企业拓展了融资渠道,吸收了大众闲散资金。但这种新兴的融资模式也存在诸多问题,如法律环境、信用体系、知识产权保护和社会认知等,可能影响企业高质量发展,让投资者的决策面临风险。本文基于信号理论,利用股权众筹平台Seedrs和Crunchbase的相关数据,从项目特征、众筹绩效、获得的广告效应三个方面,对完成股权众筹的初创企业的后续融资绩效影响因素进行了研究。研究发现,项目特征中的项目估值、目标金额、出让股权份额、政策优惠程度,以及众筹绩效中的先前的融资经历、获得的广告效应中的投资者数量,均会显著正向影响后续融资绩效(是否获得后续融资、后续融资所需时间或后续融资金额)。除此之外,项目视频介绍长度、所在城市等级、公司经营对象、数字化程度、融资完成时间、公司年龄对于后续融资也有一定影响。本文研究结论可为投资者、创业者和平台提供有效的决策参考。

基于故障安全域的混合级联直流输电系统后续换相失败抑制策略

混合级联直流输电系统兼顾了电网换相换流器(LCC)和模块化多电平换流器(MMC)的优势,具有良好的工程应用前景,但系统逆变侧LCC与MMC间复杂的交直流耦合特性增加了后续换相失败的抑制难度。为此,该文提出了一种应对混合级联系统后续换相失败的协调控制策略。首先,分析了控制器交互期间电气量波动和LCC无功需求对系统恢复产生的不利影响,并在考虑控制器作用和MMC动态无功支撑的基础上建立了多电气量耦合作用下的故障安全域;其次,通过对混合级联系统和基于电网换相换流器的高压直流输电故障安全域对比分析,提出了一种基于MMC和低压限流环节(VDCOL)的协调控制策略,以实现系统后续换相失败抑制和功率快速平稳恢复相协调;最后,基于PSCAD/EMTDC分别在不同严重程度交流故障、不同短路比和不同故障持续时间下进行仿真对比分析,验证了所提协调控制策略的有效性。

时间序列上的变化查询的高效处理算法

时间序列数据的值的变化往往代表着事件的发生。时间序列数据上的变化查询,即查找在一定长度内,满足增长或减少一定阈值的子序列,可以挖掘事件,有重要实际意义。现有方法无法高效解决该问题。为此,一种基于分段并构建分段关系图的方法被提出。实验表明,该方法在百万长度的时间序列下仍可在百毫秒内返回结果,且分段关系图的存储开销也较小。对于波动较少的数据集,存储大小可达到原数据集大小的30%以下。且进一步提出了两种优化手段,可在原有基础上再减少约50%的存储开销,同时不过多影响查询效率。

基于组合赋权法分析后续回击对线路反击跳闸影响研究

为探究后续回击对500 kV输电线路反击跳闸率的影响,文章统计出后续回击的次数及雷电流幅值的分布规律。通过组合赋权法分析了不含后续回击的首次回击、含后续回击的首次回击及后续回击的次数和雷电流幅值对线路反击跳闸的影响。根据后续回击次数与雷电流幅值在反击跳闸的影响比重,确定后续回击次数是线路反击跳闸的主要影响因素。根据组合赋权法分析结果,提出了一种考虑后续回击的反击闪络模型,通过ATP-EMTP模型分析后续回击对反击耐雷水平的影响。仿真结果可知:首次回击未跳闸时,考虑后续回击线路的反击耐雷水平会降低,降低程度与导线工频电压周期有关,平均降低原反击耐雷水平的36.4%。仿真结果和理论分析结果一致,可为输电线路运维和防雷设计提供有效的理论支撑。

计及电网侧储能交互作用的MIDC后续换相失败机理分析及抑制策略

利用电网侧储能的无功支撑能力有望改善多馈入直流输电(multi-infeed high voltage direct current,MIDC)的电压暂态特性,但是电网侧储能接入后,电力电子装备之间的相互作用会影响MIDC控制特性。在计及电网侧储能与MIDC交互作用基础上,分析了故障持续阶段与故障清除阶段的MIDC后续换相失败机理。研究表明,在故障持续阶段,由于电网侧储能的交互作用,定电流控制切换为定关断角控制时直流电流更大,并且电流偏差控制输出减少使越前触发角下降,造成换相供给面积不足的影响更大;在故障清除阶段,计及直流电流振荡影响,越前触发角下降及大幅波动会导致换相供给面积不足;在MIDC系统处于功率恢复过程中,若电网侧储能无功功率指令置为0,将增大后续换相失败风险。然后,针对电网侧储能以及MIDC控制策略进行改进,提出了计及电网侧储能交互作用的MIDC后续换相失败抑制策略。最后,在多种故障类型下仿真验证了所提控制策略有效性。

基于ICEEMDAN-MBWO-WKELM短期光伏功率预测

针对光伏发电功率随机性强、波动性大且预测精度较低等问题,提出了一种基于改进自适应白噪声完备集成经验模态分解(ICEEMDAN)和多策略改进白鲸优化算法(MBWO)优化加权核极限学习机(WKELM)预测模型。首先,根据Pearson分析确定对光伏发电功率相关性较高的气象因素,并利用Kmeans++对历史数据进行聚类得到不同天气类型的相似日集。其次,利用ICEEMDAN将原始光伏功率分解为不同频率的子序列以降低其波动性。然后,对各子序列构建WKELM预测模型,并利用MBWO优化模型的核参数和正则化系数。最后,将各子序列的预测值相加得到最终的预测结果。以国内江苏某光伏电站真实数据为例对该模型及其他模型进行算例分析,结果表明此处所提组合预测模型具有较高的预测精度。

痛风患者痛风发作对后续心血管事件的影响

目的探讨痛风患者痛风发作对后续心血管事件的影响。方法选取2020年3月至2021年2月上海交通大学医学院附属瑞金医院舟山分院内分泌科收治的80例痛风患者作为研究对象,依据是否发生心血管事件分为痛风伴心血管事件组(n=38)及痛风不伴心血管事件组(n=42)。采用logistic回归评估近期既往痛风发作对心血管事件的影响。通过比较在指数心血管事件发生180 d内某一特定时间段内发生过耀斑的患者与以前没有或有过耀斑的患者,计算最近发生过耀斑的概率。结果痛风伴心血管事件组的吸烟、饮酒、心血管疾病史高于痛风不伴心血管事件组,Charlson共病指数低于痛风不伴心血管事件组,差异有统计学意义(P<0.05)。两组患者的体重指数、痛风诊断时间、糖尿病伴靶器官损害、慢性肾病≥3期、高血压、心房颤动、高胆固醇血症、抗血小板药物、降尿酸药物、利尿剂、非甾体抗炎药、糖皮质激素和秋水仙碱方面比较,差异无统计学意义(P>0.05)。在完全调整的模型中,与痛风不伴心血管事件组相比,痛风伴心血管事件组患者在前0~60 d、>60~120 d内痛风发作的概率显著更高,但在>120~180 d内痛风发作的概率无显著差异(P<0.05)。结论在痛风患者中,经历过痛风的患者发生后续心血管事件的概率更高。

创业失败修复、创业动机与后续创业行为——规则聚焦的调节作用

创业失败修复作为创业者重启创业的关键正日益受到关注,然而现有关于创业失败修复对后续创业影响机理的研究较为薄弱。文章尝试从创业失败修复视角探究激发创业失败者后续创业行为的新路径,构建创业失败修复到后续创业的概念模型。通过数据分析发现,创业失败修复对后续创业行为具有积极的影响,创业动机在创业失败修复与后续创业行为之间起到中介作用,创业失败修复和后续创业行为间的关系受到促进型聚焦的正向调节作用。文章丰富了创业失败修复和后续创业等相关理论,对后续创业者从失败中有效修复并再次创业具有重大意义。

《维也纳条约法公约》第31.3条“Subsequent Practice”研究

从国际法制和相关案例来看,嗣后惯例的效力和构成要素是模糊的。嗣后惯例并非正式的、文本性协定,其解释性价值完全依赖于一致性的行为、所有当事方间达成的协定和作为单一的自主解释之合成解释。嗣后惯例必须是确立了当事方间的协定,当事方在条约履行中明确地实施了本质上相同或一致的行为。嗣后惯例的效力是一个颇有争议的问题,尤其是部分缔约方的惯行对原条约和其他缔约方的效力问题。相互矛盾的嗣后惯例会有不同的效力,这取决于所涉的多边条约机制。该惯例的形成有赖于国家在适用条约时有机会采取某些行动,并不要求每个当事方都必须单独地实施足以被接受为惯例的行为,只需要所有当事方接受,甚至是默示地接受。嗣后惯例与嗣后协定间存在联系与差异。

Transient receptor potential channels and calcium dysregulation: a pathogenic duo in Parkinson's disease

Parkinson's disease(PD) has a complex and multifactorial pathophysiology. Various studies, conducted both in pre-clinical models and PD patients, have reported a link between the disruption of calcium(Ca^(2+)) homeostasis and the subsequent development of PD. Ca^(2+) regulation is crucial for neuronal survival, differentiation,exocytosis at synapses,gene transcription,and proliferation.