(6-Amino-2-chloro-3-fluorophenyl)methanol is prepared through both traditional methods and palladium catalyzed iterative C–H halogenation reactions.In comparison to traditional approach,the C–H functionalization s...(6-Amino-2-chloro-3-fluorophenyl)methanol is prepared through both traditional methods and palladium catalyzed iterative C–H halogenation reactions.In comparison to traditional approach,the C–H functionalization strategy demonstrated a few advantages including milder reaction conditions higher yields,better selectivity and practicality,and high chemical diversity.展开更多
基金supported by ‘973’ Project (No. 2011CB965300)NSFC (Nos. 21142008, 21302106)+1 种基金Tsinghua University 985 Phase II Fundsthe Tsinghua University Initiative Scientific Research Program
文摘(6-Amino-2-chloro-3-fluorophenyl)methanol is prepared through both traditional methods and palladium catalyzed iterative C–H halogenation reactions.In comparison to traditional approach,the C–H functionalization strategy demonstrated a few advantages including milder reaction conditions higher yields,better selectivity and practicality,and high chemical diversity.