Perspectives on “the biology of spinal cord regeneration success and failure”

In our recently co-authored Physiological Reviews manuscript entitled ＂The biology of regeneration failure and success after spinal cord injury＂ （Tran et al., 2018b）, we sought to provide a comprehensive and up-to-date de- scription of how the glial scar develops following spinal cord injury （SCI） to chronically inhibit axon regeneration.

Empirical Analysis of Software Success Rate Forecasting During Requirement Engineering Processes

Forecasting on success or failure of software has become an interesting and,in fact,an essential task in the software development industry.In order to explore the latest data on successes and failures,this research focused on certain questions such as is early phase of the software development life cycle better than later phases in predicting software success and avoiding high rework?What human factors contribute to success or failure of a software?What software practices are used by the industry practitioners to achieve high quality of software in their day-to-day work?In order to conduct this empirical analysis a total of 104 practitioners were recruited to determine how human factors,misinterpretation,and miscommunication of requirements and decision-making processes play their roles in software success forecasting.We discussed a potential relationship between forecasting of software success or failure and the development processes.We noticed that experienced participants had more confidence in their practices and responded to the questionnaire in this empirical study,and they were more likely to rate software success forecasting linking to the development processes.Our analysis also shows that cognitive bias is the central human factor that negatively affects forecasting of software success rate.The results of this empirical study also validated that requirements’misinterpretation and miscommunication were themain causes behind software systems’failure.It has been seen that reliable,relevant,and trustworthy sources of information help in decision-making to predict software systems’success in the software industry.This empirical study highlights a need for other software practitioners to avoid such bias while working on software projects.Future investigation can be performed to identify the other human factors that may impact software systems’success.

Factors of Failure of Community Interventions of PMTCT Activities in Haut Katanga in the Democratic Republic of Congo

The objective of the study was to identify the failure factors of community interventions in terms of HIV activities in the province of Haut-Katanga during the year 2016. Materials and Methods: The study was phenomenological of the factors, carried out in Haut Katanga. All health facilities (FOSAs) having integrated the prevention of transmission of HIV infection from mother to child (PMTCT) were included in the study. The collection was carried out through individual semi-structured interviews with PMTCT focal points, mentor mothers and people living with HIV (PLWHA) cared for in some of these health facilities (FOSAs). The number of participants was determined by the saturation of responses. Nvivo v.11 software was used for the analyses. The data of each woman was handled confidentially. The authorization of the ethics committee of the University of Kinshasa ESP/CE091/2015, the free and written consent, was obtained before collecting the information. Results: It was observed the socio-cultural factors of success and failure of the interventions: the social fear generated by contradictory messages in the sensitization of the community;the lack of an obvious strategy for the involvement of the partner;the weak coordination of community care activities between the central office of the health zone;the FOSA and the community worker: low interest in community care evidenced by weak accountability of FOSAs, community and program providers in this regard;that relates to community activities;coordination of care between care units;overload of the staff in charge of activities within the health structure and their low motivation;the low communication time devoted to people living with HIV in the FOSAs. Conclusion: The study shows that interventions that can improve the quality and outcomes of prevention of mother-to-child transmission of HIV (PMTCT) services can be directly linked to the program itself, as well as come from another or the community, which generally remains the weak link in which efforts are even less noticeable, at least as far as PMTCT is concerned. Integrating care data for the mother-child couple improve the continuum of services between the different care units as well as the quality of data management.