Laser ablation coupled with inductively coupled plasma-mass spectrometry (LA-ICP-MS) calibration was conducted with multiple spot analyses on eleven intact rock samples using both an internal standard (IS) method and ...Laser ablation coupled with inductively coupled plasma-mass spectrometry (LA-ICP-MS) calibration was conducted with multiple spot analyses on eleven intact rock samples using both an internal standard (IS) method and a modified constant-sum (MCS) method. Methods were then compared for reported bulk elemental composition of the rocks. The MCS method was based on the sum of eight major elements, which is spatially more stable than one single major ele-ment as used in the IS method, and is quite constant among different rock samples. Calibrations were performed with standard reference materials NIST SRM 610, 612, 614, and 616. Little difference was found between using a single standard and a set of standards, because of the good linearity shown by the reference materials. Comparison of the two calibration methods shows that the MCS method produced better and more stable results than the IS method for heterogeneous samples. With the MCS method, approximately 94% to 95% of the total measurements are within the range of ±100% relative deviation, compared with 82% to 86% with the IS method. The IS method resulted insubstantial overestimations for some rock samples (e.g., 648% for Basalt BCR-2 using NIST SRM 610 as the calibration standard), while the largest deviation with the MCS method was 216% for U in Eagle Ford shale #80 sample. For Quartz latite QLO-1, a relative homogeneous sample, the IS method generated slightly better results than the MCS method. Regardless of method, spatially heterogeneous distribution of elements in the intact rock at the scale of the laser spot is considered to be the main reason for the large relative deviations seen in our work compared to published results.展开更多
Slope stability analysis is a classical mechanical problem in geotechnical engineering and engineering geology.It is of great significance to study the stability evolution of expansive soil slopes for engineering cons...Slope stability analysis is a classical mechanical problem in geotechnical engineering and engineering geology.It is of great significance to study the stability evolution of expansive soil slopes for engineering construction in expansive soil areas.Most of the existing studies evaluate the slope stability by analyzing the limit equilibrium state of the slope,and the analysis method for the stability evolution considering the damage softening of the shear zone is lacking.In this study,the large deformation shear mechanical behavior of expansive soil was investigated by ring shear test.The damage softening characteristic of expansive soil in the shear zone was analyzed,and a shear damage model reflecting the damage softening behavior of expansive soil was derived based on the damage theory.Finally,by skillfully combining the vector sum method and the shear damage model,an analysis method for the stability evolution of the expansive soil slope considering the shear zone damage softening was proposed.The results show that the shear zone subjected to large displacement shear deformation exhibits an obvious damage softening phenomenon.The damage variable equation based on the logistic function can be well used to describe the shear damage characteristics of expansive soil,and the proposed shear damage model is in good agreement with the ring shear test results.The vector sum method considering the damage softening behavior of the shear zone can be well applied to analyze the stability evolution characteristics of the expansive soil slope.The stability factor of the expansive soil slope decreases with the increase of shear displacement,showing an obvious progressive failure behavior.展开更多
The vibration characteristics and dynamic responses of rock and soil under seismic load can be estimated with dynamic finite element method (DFEM). Combining with the DFEM, the vector sum analysis method (VSAM) is...The vibration characteristics and dynamic responses of rock and soil under seismic load can be estimated with dynamic finite element method (DFEM). Combining with the DFEM, the vector sum analysis method (VSAM) is employed in seismic stability analysis of a slope in this paper. Different from other conventional methods, the VSAM is proposed based on the vector characteristic of force and current stress state of the slope. The dynamic stress state of the slope at any moment under seismic load can he obtained by the DFEM, thus the factor of safety of the slope at any moment during earthquake can be easily obtained with the VSAM in consideration of the DFEM. Then, the global stability of the slope can be estimated on the basis of time-history curve of factor of safety and reliability theory. The VSAM is applied to a homogeneous slope under seismic load. The factor of safety of the slope is 1.30 under gravity only and the dynamic factor of safety under seismic load is 1.21. The calculating results show that the dynamic characteristics and stability state of the slope with input ground motion can be actually analyzed. It is believed that the VSAM is a feasible and practical approach to estimate the dynamic stability of slopes under seismic load.展开更多
Tumor diagnosis by analyzing gene expression profiles becomes an interesting topic in bioinformatics and the main problem is to identify the genes related to a tumor. This paper proposes a rank sum method to identify ...Tumor diagnosis by analyzing gene expression profiles becomes an interesting topic in bioinformatics and the main problem is to identify the genes related to a tumor. This paper proposes a rank sum method to identify the re- lated genes based on the rank sum test theory in statistics. The tumor diagnosis system is constructed by the support vector machine (SVM) trained on the set of the related gene expression profiles. The experiments demonstrate that the constructed tumor diagnosis system with the rank sum method and SVM can reach an accuracy level of 96.2% on the colon data and 100% on the leukemia data.展开更多
There are a few studies that focus on solution methods for finding a Nash equilibrium of zero-sum games. We discuss the use of Karmarkar’s interior point method to solve the Nash equilibrium problems of a zero-sum ga...There are a few studies that focus on solution methods for finding a Nash equilibrium of zero-sum games. We discuss the use of Karmarkar’s interior point method to solve the Nash equilibrium problems of a zero-sum game, and prove that it is theoretically a polynomial time algorithm. We implement the Karmarkar method, and a preliminary computational result shows that it performs well for zero-sum games. We also mention an affine scaling method that would help us compute Nash equilibria of general zero-sum games effectively.展开更多
In this paper, we study the solutions for variable-order time-fractional diffusion equations. A three-point combined compact difference (CCD) method is used to discretize the spatial variables to achieve sixth-order a...In this paper, we study the solutions for variable-order time-fractional diffusion equations. A three-point combined compact difference (CCD) method is used to discretize the spatial variables to achieve sixth-order accuracy, while the exponential-sum-approximation (ESA) is used to approximate the variable-order Caputo fractional derivative in the temporal direction, and a novel spatial sixth-order hybrid ESA-CCD method is implemented successfully. Finally, the accuracy of the proposed method is verified by numerical experiments.展开更多
It is well established that Nash equilibrium exists within the framework of mixed strategies in strategic-form non-cooperative games. However, finding the Nash equilibrium generally belongs to the class of problems kn...It is well established that Nash equilibrium exists within the framework of mixed strategies in strategic-form non-cooperative games. However, finding the Nash equilibrium generally belongs to the class of problems known as PPAD (Polynomial Parity Argument on Directed graphs), for which no polynomial-time solution methods are known, even for two-player games. This paper demonstrates that in fixed-sum two-player games (including zero-sum games), the Nash equilibrium forms a convex set, and has a unique expected payoff. Furthermore, these equilibria are Pareto optimal. Additionally, it is shown that the Nash equilibrium of fixed-sum two-player games can theoretically be found in polynomial time using the principal-dual interior point method, a solution method of linear programming.展开更多
Molecular microbiological methods, such as competetive PCR, real-time PCR, denaturing gradient gel electrophoresis (DGGE) and large-scale parallel-pyrosequencing, require the extraction of sufficient quantity of high ...Molecular microbiological methods, such as competetive PCR, real-time PCR, denaturing gradient gel electrophoresis (DGGE) and large-scale parallel-pyrosequencing, require the extraction of sufficient quantity of high quality DNA from microbiologically and chemically complex matrices. Due to difficulties in the field to standardize/select the optimum DNA preservation-extraction methods in view of laboratories differences, this article attempts to present a straight-forward mathematical framework for comparing some of the most commonly used methods. To this end, as a case study, the problem of selecting an optimum sample preservation-DNA extraction strategy for obtaining total bacterial DNA from swine feces was considered. Two sample preservation methods (liquid nitrogen and RNAlater?) and seven extraction techniques were paired and compared under six quantitative DNA analysis criteria: yield of extraction, purity of extracted DNA (A260/280 and A 260/230 ratios), duration of extraction, degradation degree of DNA, and cost. From a practical point of view, it is unlikely that a single sample preservation-DNA extraction strategy can be optimum for all selected criteria. Hence, a systematic multi-criteria decision-making (MCDM) approach was used to compare the methods. As a result, the ZR Fecal DNA MiniPrepTM DNA extraction kit for samples preserved either with liquid nitrogen or RNAlater? were identified as potential optimum solutions for obtaining total bacterial DNA from swine feces. Considering the need for practicality for in situ applications, we would recommend liquid nitrogen as sample preservation method, along with the ZR Fecal DNA MiniPrepTM kit. Total bacterial DNA obtained by this strategy can be suitable for downstream PCR-based DNA analyses of swine feces.展开更多
This paper deals with the Alienor method to tackle multiobjective nonlinear optimization problems. In this approach, the multiple criteria of the optimization problem are aggregated into a single one using weighted su...This paper deals with the Alienor method to tackle multiobjective nonlinear optimization problems. In this approach, the multiple criteria of the optimization problem are aggregated into a single one using weighted sums. Then, the resulting single objective nonlinear optimization problem is solved using the Alienor method associated with the Optimization Preserving Operators technique which has proved to be suitable for (nonlinear) optimization problems with a large number of variables (see [1]). The proposed approach is evaluated through test problems. The results show that the approach provides good approximations of the Pareto front while requiring small computational time, even for large instances.展开更多
In this paper, the sum deviation just-in-time (JIT) sequencing problem in mixed-model production systems is studied relating with the discrete apportionment problem together with their respective mathematical formul...In this paper, the sum deviation just-in-time (JIT) sequencing problem in mixed-model production systems is studied relating with the discrete apportionment problem together with their respective mathematical formulations. The assignment formulation for the first problem is briefly discussed followed by the existence of JIT cyclic sequences. Presenting the concise discussion on divisor methods for the discrete apportionment problem, we have proposed two mean-based divisor functions for this problem claiming that they are better than the existing divisors; hence, we found a better bound for the JIT sequencing problem. The linkage of both the problems is characterized in terms of similar type of objective functions. The problems are shown equivalent via suitable transformations and similar properties. The joint approaches for the two problems are discussed in terms of global and local deviations proposing equitably efficient solution.展开更多
文摘Laser ablation coupled with inductively coupled plasma-mass spectrometry (LA-ICP-MS) calibration was conducted with multiple spot analyses on eleven intact rock samples using both an internal standard (IS) method and a modified constant-sum (MCS) method. Methods were then compared for reported bulk elemental composition of the rocks. The MCS method was based on the sum of eight major elements, which is spatially more stable than one single major ele-ment as used in the IS method, and is quite constant among different rock samples. Calibrations were performed with standard reference materials NIST SRM 610, 612, 614, and 616. Little difference was found between using a single standard and a set of standards, because of the good linearity shown by the reference materials. Comparison of the two calibration methods shows that the MCS method produced better and more stable results than the IS method for heterogeneous samples. With the MCS method, approximately 94% to 95% of the total measurements are within the range of ±100% relative deviation, compared with 82% to 86% with the IS method. The IS method resulted insubstantial overestimations for some rock samples (e.g., 648% for Basalt BCR-2 using NIST SRM 610 as the calibration standard), while the largest deviation with the MCS method was 216% for U in Eagle Ford shale #80 sample. For Quartz latite QLO-1, a relative homogeneous sample, the IS method generated slightly better results than the MCS method. Regardless of method, spatially heterogeneous distribution of elements in the intact rock at the scale of the laser spot is considered to be the main reason for the large relative deviations seen in our work compared to published results.
基金supported by the National Key Research and Development Program of China(Grant No.2019YFC1509901).
文摘Slope stability analysis is a classical mechanical problem in geotechnical engineering and engineering geology.It is of great significance to study the stability evolution of expansive soil slopes for engineering construction in expansive soil areas.Most of the existing studies evaluate the slope stability by analyzing the limit equilibrium state of the slope,and the analysis method for the stability evolution considering the damage softening of the shear zone is lacking.In this study,the large deformation shear mechanical behavior of expansive soil was investigated by ring shear test.The damage softening characteristic of expansive soil in the shear zone was analyzed,and a shear damage model reflecting the damage softening behavior of expansive soil was derived based on the damage theory.Finally,by skillfully combining the vector sum method and the shear damage model,an analysis method for the stability evolution of the expansive soil slope considering the shear zone damage softening was proposed.The results show that the shear zone subjected to large displacement shear deformation exhibits an obvious damage softening phenomenon.The damage variable equation based on the logistic function can be well used to describe the shear damage characteristics of expansive soil,and the proposed shear damage model is in good agreement with the ring shear test results.The vector sum method considering the damage softening behavior of the shear zone can be well applied to analyze the stability evolution characteristics of the expansive soil slope.The stability factor of the expansive soil slope decreases with the increase of shear displacement,showing an obvious progressive failure behavior.
基金Supported by the Program of Yunnan Provincial Institute of Communications Planning,Design and Research (2011(D)11-b)
文摘The vibration characteristics and dynamic responses of rock and soil under seismic load can be estimated with dynamic finite element method (DFEM). Combining with the DFEM, the vector sum analysis method (VSAM) is employed in seismic stability analysis of a slope in this paper. Different from other conventional methods, the VSAM is proposed based on the vector characteristic of force and current stress state of the slope. The dynamic stress state of the slope at any moment under seismic load can he obtained by the DFEM, thus the factor of safety of the slope at any moment during earthquake can be easily obtained with the VSAM in consideration of the DFEM. Then, the global stability of the slope can be estimated on the basis of time-history curve of factor of safety and reliability theory. The VSAM is applied to a homogeneous slope under seismic load. The factor of safety of the slope is 1.30 under gravity only and the dynamic factor of safety under seismic load is 1.21. The calculating results show that the dynamic characteristics and stability state of the slope with input ground motion can be actually analyzed. It is believed that the VSAM is a feasible and practical approach to estimate the dynamic stability of slopes under seismic load.
文摘Tumor diagnosis by analyzing gene expression profiles becomes an interesting topic in bioinformatics and the main problem is to identify the genes related to a tumor. This paper proposes a rank sum method to identify the re- lated genes based on the rank sum test theory in statistics. The tumor diagnosis system is constructed by the support vector machine (SVM) trained on the set of the related gene expression profiles. The experiments demonstrate that the constructed tumor diagnosis system with the rank sum method and SVM can reach an accuracy level of 96.2% on the colon data and 100% on the leukemia data.
文摘There are a few studies that focus on solution methods for finding a Nash equilibrium of zero-sum games. We discuss the use of Karmarkar’s interior point method to solve the Nash equilibrium problems of a zero-sum game, and prove that it is theoretically a polynomial time algorithm. We implement the Karmarkar method, and a preliminary computational result shows that it performs well for zero-sum games. We also mention an affine scaling method that would help us compute Nash equilibria of general zero-sum games effectively.
文摘In this paper, we study the solutions for variable-order time-fractional diffusion equations. A three-point combined compact difference (CCD) method is used to discretize the spatial variables to achieve sixth-order accuracy, while the exponential-sum-approximation (ESA) is used to approximate the variable-order Caputo fractional derivative in the temporal direction, and a novel spatial sixth-order hybrid ESA-CCD method is implemented successfully. Finally, the accuracy of the proposed method is verified by numerical experiments.
文摘It is well established that Nash equilibrium exists within the framework of mixed strategies in strategic-form non-cooperative games. However, finding the Nash equilibrium generally belongs to the class of problems known as PPAD (Polynomial Parity Argument on Directed graphs), for which no polynomial-time solution methods are known, even for two-player games. This paper demonstrates that in fixed-sum two-player games (including zero-sum games), the Nash equilibrium forms a convex set, and has a unique expected payoff. Furthermore, these equilibria are Pareto optimal. Additionally, it is shown that the Nash equilibrium of fixed-sum two-player games can theoretically be found in polynomial time using the principal-dual interior point method, a solution method of linear programming.
文摘Molecular microbiological methods, such as competetive PCR, real-time PCR, denaturing gradient gel electrophoresis (DGGE) and large-scale parallel-pyrosequencing, require the extraction of sufficient quantity of high quality DNA from microbiologically and chemically complex matrices. Due to difficulties in the field to standardize/select the optimum DNA preservation-extraction methods in view of laboratories differences, this article attempts to present a straight-forward mathematical framework for comparing some of the most commonly used methods. To this end, as a case study, the problem of selecting an optimum sample preservation-DNA extraction strategy for obtaining total bacterial DNA from swine feces was considered. Two sample preservation methods (liquid nitrogen and RNAlater?) and seven extraction techniques were paired and compared under six quantitative DNA analysis criteria: yield of extraction, purity of extracted DNA (A260/280 and A 260/230 ratios), duration of extraction, degradation degree of DNA, and cost. From a practical point of view, it is unlikely that a single sample preservation-DNA extraction strategy can be optimum for all selected criteria. Hence, a systematic multi-criteria decision-making (MCDM) approach was used to compare the methods. As a result, the ZR Fecal DNA MiniPrepTM DNA extraction kit for samples preserved either with liquid nitrogen or RNAlater? were identified as potential optimum solutions for obtaining total bacterial DNA from swine feces. Considering the need for practicality for in situ applications, we would recommend liquid nitrogen as sample preservation method, along with the ZR Fecal DNA MiniPrepTM kit. Total bacterial DNA obtained by this strategy can be suitable for downstream PCR-based DNA analyses of swine feces.
文摘This paper deals with the Alienor method to tackle multiobjective nonlinear optimization problems. In this approach, the multiple criteria of the optimization problem are aggregated into a single one using weighted sums. Then, the resulting single objective nonlinear optimization problem is solved using the Alienor method associated with the Optimization Preserving Operators technique which has proved to be suitable for (nonlinear) optimization problems with a large number of variables (see [1]). The proposed approach is evaluated through test problems. The results show that the approach provides good approximations of the Pareto front while requiring small computational time, even for large instances.
基金supported by the e-LINK project (EM ECW-ref.149674-EM-1-UK-ERAMUNDUS)financial support to carry out the work at Staffordshire University, Stafford, UK
文摘In this paper, the sum deviation just-in-time (JIT) sequencing problem in mixed-model production systems is studied relating with the discrete apportionment problem together with their respective mathematical formulations. The assignment formulation for the first problem is briefly discussed followed by the existence of JIT cyclic sequences. Presenting the concise discussion on divisor methods for the discrete apportionment problem, we have proposed two mean-based divisor functions for this problem claiming that they are better than the existing divisors; hence, we found a better bound for the JIT sequencing problem. The linkage of both the problems is characterized in terms of similar type of objective functions. The problems are shown equivalent via suitable transformations and similar properties. The joint approaches for the two problems are discussed in terms of global and local deviations proposing equitably efficient solution.