The linear hexapeptide(His-Gly-Asp) was synthesized on solid support.FM group was used for a carboxyl protection group at Aspl.Peptide was cyclizsed by BOP reagent while still attached to the solid support.BOP proceed...The linear hexapeptide(His-Gly-Asp) was synthesized on solid support.FM group was used for a carboxyl protection group at Aspl.Peptide was cyclizsed by BOP reagent while still attached to the solid support.BOP proceeded more rapidly and gave purer product than DCC/HOBt method.展开更多
文摘The linear hexapeptide(His-Gly-Asp) was synthesized on solid support.FM group was used for a carboxyl protection group at Aspl.Peptide was cyclizsed by BOP reagent while still attached to the solid support.BOP proceeded more rapidly and gave purer product than DCC/HOBt method.
