A new microreactor with continuous serially connected micromixers(CSCM)was tailored for the coprecipitation process to synthesize Fe_(3)O_(4) nanoparticles.Numerical simulation reveals that the two types of CSCM micro...A new microreactor with continuous serially connected micromixers(CSCM)was tailored for the coprecipitation process to synthesize Fe_(3)O_(4) nanoparticles.Numerical simulation reveals that the two types of CSCM microchannels(V-typed and U-typed)proposed in this work exhibited markedly better mixing performances than the Zigzag and capillary microchannels due to the promotion of Dean vortices.Complete mixing was achieved in the V-typed microchannel in 2.7 s at an inlet Reynolds number of 27.Fe_(3)O_(4) nanoparticles synthesized in a planar glass microreactor with the V-typed microchannel,possessing an average size of 9.3 nm and exhibiting superparamagnetism,had obviously better dispersity and uniformity and higher crystallinity than those obtained in the capillary microreactor.The new CSCM microreactor developed in this work can act as a potent device to intensify the synthesis of similar inorganic nanoparticles via multistep chemical precipitation processes.展开更多
We have previously reported on both the osteogenic potential of hydroxyapatite (HA) combined with bone marrow-derived mesenchymal stem cells (BMSCs) and a method involving osteogenic matrix cell sheet transplantation ...We have previously reported on both the osteogenic potential of hydroxyapatite (HA) combined with bone marrow-derived mesenchymal stem cells (BMSCs) and a method involving osteogenic matrix cell sheet transplantation of BMSCs. In the present study, we assessed the osteogenic potential of serially-passaged BMSCs, both in vitro and in vivo. We also assessed whether an additional cell-loading technique can regain the osteogenic potential of the constructs combined with serially-passaged BMSCs. The present study revealed that passage (P) 1 cells cultured in osteogenic-induced medium showed strong positive staining for alkaline phosphatase (ALP) and Alizarin Red S, whereas P3 cells showed faint staining for ALP, with no Alizarin Red S staining. Staining of P1, P2 and P3 cells were progressively weaker, indicating that the osteogenic potential of the serially-passaged rat BMSCs is lost after P3 in vitro. The in vivo study showed that little bone formation was observed in the HA constructs seeded with P3 cells, 4 weeks after subcutaneous implantation. However, P3 cell/HA constructs which had increased cell-loading showed abundant bone formation within the pores of the HA construct. ALP and osteocalcin mRNA expression in these constructs was significantly higher than that of constructs with regular cell-seeding. The present study indicates that the osteogenic potential of the constructs with serially-passaged BMSCs is increased by additional cell-loading. This method can be applied to cases requiring hard tissue reconstruction, where BMSCs require serial expansion of cells.展开更多
To improve the performance of the short interleaved serial concatenated convolutional code(SCCC) with low decoding iterative times, the structure of Log MAP algorithm is introduced into the conventional SOVA decoder...To improve the performance of the short interleaved serial concatenated convolutional code(SCCC) with low decoding iterative times, the structure of Log MAP algorithm is introduced into the conventional SOVA decoder to improve its performance at short interleaving delay. The combination of Log MAP and SOVA avoids updating the matrices of the maximum path, and also makes a contribution to the requirement of short delay. The simulation results of several SCCCs show that the improved decoder can obtain satisfied performance with short frame interleaver and it is suitable to the high bit rate low delay communication systems.展开更多
A mine-used multi-function serial signal converter is introduced.This converter is based on Ethernet.The core of this design is embedded microprocessor STM32F107VCT6.Embedded operation system μC/OS-Ⅱ is transplanted...A mine-used multi-function serial signal converter is introduced.This converter is based on Ethernet.The core of this design is embedded microprocessor STM32F107VCT6.Embedded operation system μC/OS-Ⅱ is transplanted into this converter,and light-weight Internet protocal （LwIP） stack is also embedded to realize mutual conversion of serial signals such as meter bus （M-Bus） signal,RS485 signal,RS232 signal and Ethernet signal.Interconnection between all kinds of monitoring system interfaces under coal mine can be formed easily,which can solve compatibility problem between monitoring system and communication system and improve overall performance of safety monitoring system.The designed multi-function serial signal converter is of great value for application,which is worthy to be popularized in coal mine safety production.展开更多
This editorial is a commentary on the case report by Furuya et al focusing on the challenging diagnosis of early pancreatic adenocarcinoma and new tools for an earlier diagnosis.Currently,pancreatic cancer still has a...This editorial is a commentary on the case report by Furuya et al focusing on the challenging diagnosis of early pancreatic adenocarcinoma and new tools for an earlier diagnosis.Currently,pancreatic cancer still has a poor prognosis,mainly due to late diagnosis in an advanced stage.Two main precancerous routes have been identified as pathways to pancreatic adenocarcinoma:The first encompasses a large group of mucinous cystic lesions:intraductal papillary mucinous neoplasm and mucinous cystic neoplasm,and the second is pancreatic intraepithelial neoplasia.In the last decade the focus of research has been to identify high-risk patients,using advanced imaging techniques(magnetic resonance cholangiopancreatography or endoscopic ultrasonography)which could be helpful in finding“indirect signs”of early stage pancreatic lesions.Nevertheless,the survival rate still remains poor,and alternative screening methods are under investigation.Endoscopic retrograde cholangiopancreatography followed by serial pancreatic juice aspiration cytology could be a promising tool for identifying precursor lesions such as intraductal papillary mucinous neoplasm,but confirming data are still needed to validate its role.Probably a combination of cross-sectional imaging,endoscopic techniques(old and new ones)and genetic and biological biomarkers also in pancreatic juice)could be the best solution to reach an early diagnosis.Biomarkers could help to predict and follow the progression of early pancreatic lesions.However,further studies are needed to validate their diagnostic reliability and to establish diagnostic algorithms to improve prognosis and survival in patients with pancreatic cancer.展开更多
The women of the 1930s in the Chinese TV serials deduct inspiring stories.They play different roles in the big wealthy families such as mothers-in-law,daughters-in-law,and maidservants.There are unceasing conflicts be...The women of the 1930s in the Chinese TV serials deduct inspiring stories.They play different roles in the big wealthy families such as mothers-in-law,daughters-in-law,and maidservants.There are unceasing conflicts between these women,because of their struggle for men's love,wealth or social position.The theme of their stories is always about fertility,love,kindness and evil,with the ending being either comic or tragic.The stories of various kinds of women of the 1930s in the Chinese TV serials decorate and enrich the lives of many of us latecomers and their names are passed on from generation to generation.展开更多
Empty categories,which lack phonological form and hence are not visible in the phonetic representation of the sentence,have both syntactic and semantic properties.Null subjects PRO and pro are base-generated empty cat...Empty categories,which lack phonological form and hence are not visible in the phonetic representation of the sentence,have both syntactic and semantic properties.Null subjects PRO and pro are base-generated empty categories.This thesis,based on Chomsky's theory about empty categories and research achievements made by Chinese scholars,attempts to analyze the liandong(Serial Verb) construction from Figure and Ground perspective.展开更多
基金the financial support from the National Natural Science Foundation of China(21808059)the Fundamental Research Funds for the Central Universities(JKA01221712).
文摘A new microreactor with continuous serially connected micromixers(CSCM)was tailored for the coprecipitation process to synthesize Fe_(3)O_(4) nanoparticles.Numerical simulation reveals that the two types of CSCM microchannels(V-typed and U-typed)proposed in this work exhibited markedly better mixing performances than the Zigzag and capillary microchannels due to the promotion of Dean vortices.Complete mixing was achieved in the V-typed microchannel in 2.7 s at an inlet Reynolds number of 27.Fe_(3)O_(4) nanoparticles synthesized in a planar glass microreactor with the V-typed microchannel,possessing an average size of 9.3 nm and exhibiting superparamagnetism,had obviously better dispersity and uniformity and higher crystallinity than those obtained in the capillary microreactor.The new CSCM microreactor developed in this work can act as a potent device to intensify the synthesis of similar inorganic nanoparticles via multistep chemical precipitation processes.
文摘We have previously reported on both the osteogenic potential of hydroxyapatite (HA) combined with bone marrow-derived mesenchymal stem cells (BMSCs) and a method involving osteogenic matrix cell sheet transplantation of BMSCs. In the present study, we assessed the osteogenic potential of serially-passaged BMSCs, both in vitro and in vivo. We also assessed whether an additional cell-loading technique can regain the osteogenic potential of the constructs combined with serially-passaged BMSCs. The present study revealed that passage (P) 1 cells cultured in osteogenic-induced medium showed strong positive staining for alkaline phosphatase (ALP) and Alizarin Red S, whereas P3 cells showed faint staining for ALP, with no Alizarin Red S staining. Staining of P1, P2 and P3 cells were progressively weaker, indicating that the osteogenic potential of the serially-passaged rat BMSCs is lost after P3 in vitro. The in vivo study showed that little bone formation was observed in the HA constructs seeded with P3 cells, 4 weeks after subcutaneous implantation. However, P3 cell/HA constructs which had increased cell-loading showed abundant bone formation within the pores of the HA construct. ALP and osteocalcin mRNA expression in these constructs was significantly higher than that of constructs with regular cell-seeding. The present study indicates that the osteogenic potential of the constructs with serially-passaged BMSCs is increased by additional cell-loading. This method can be applied to cases requiring hard tissue reconstruction, where BMSCs require serial expansion of cells.
文摘To improve the performance of the short interleaved serial concatenated convolutional code(SCCC) with low decoding iterative times, the structure of Log MAP algorithm is introduced into the conventional SOVA decoder to improve its performance at short interleaving delay. The combination of Log MAP and SOVA avoids updating the matrices of the maximum path, and also makes a contribution to the requirement of short delay. The simulation results of several SCCCs show that the improved decoder can obtain satisfied performance with short frame interleaver and it is suitable to the high bit rate low delay communication systems.
文摘A mine-used multi-function serial signal converter is introduced.This converter is based on Ethernet.The core of this design is embedded microprocessor STM32F107VCT6.Embedded operation system μC/OS-Ⅱ is transplanted into this converter,and light-weight Internet protocal （LwIP） stack is also embedded to realize mutual conversion of serial signals such as meter bus （M-Bus） signal,RS485 signal,RS232 signal and Ethernet signal.Interconnection between all kinds of monitoring system interfaces under coal mine can be formed easily,which can solve compatibility problem between monitoring system and communication system and improve overall performance of safety monitoring system.The designed multi-function serial signal converter is of great value for application,which is worthy to be popularized in coal mine safety production.
文摘This editorial is a commentary on the case report by Furuya et al focusing on the challenging diagnosis of early pancreatic adenocarcinoma and new tools for an earlier diagnosis.Currently,pancreatic cancer still has a poor prognosis,mainly due to late diagnosis in an advanced stage.Two main precancerous routes have been identified as pathways to pancreatic adenocarcinoma:The first encompasses a large group of mucinous cystic lesions:intraductal papillary mucinous neoplasm and mucinous cystic neoplasm,and the second is pancreatic intraepithelial neoplasia.In the last decade the focus of research has been to identify high-risk patients,using advanced imaging techniques(magnetic resonance cholangiopancreatography or endoscopic ultrasonography)which could be helpful in finding“indirect signs”of early stage pancreatic lesions.Nevertheless,the survival rate still remains poor,and alternative screening methods are under investigation.Endoscopic retrograde cholangiopancreatography followed by serial pancreatic juice aspiration cytology could be a promising tool for identifying precursor lesions such as intraductal papillary mucinous neoplasm,but confirming data are still needed to validate its role.Probably a combination of cross-sectional imaging,endoscopic techniques(old and new ones)and genetic and biological biomarkers also in pancreatic juice)could be the best solution to reach an early diagnosis.Biomarkers could help to predict and follow the progression of early pancreatic lesions.However,further studies are needed to validate their diagnostic reliability and to establish diagnostic algorithms to improve prognosis and survival in patients with pancreatic cancer.
文摘The women of the 1930s in the Chinese TV serials deduct inspiring stories.They play different roles in the big wealthy families such as mothers-in-law,daughters-in-law,and maidservants.There are unceasing conflicts between these women,because of their struggle for men's love,wealth or social position.The theme of their stories is always about fertility,love,kindness and evil,with the ending being either comic or tragic.The stories of various kinds of women of the 1930s in the Chinese TV serials decorate and enrich the lives of many of us latecomers and their names are passed on from generation to generation.
文摘Empty categories,which lack phonological form and hence are not visible in the phonetic representation of the sentence,have both syntactic and semantic properties.Null subjects PRO and pro are base-generated empty categories.This thesis,based on Chomsky's theory about empty categories and research achievements made by Chinese scholars,attempts to analyze the liandong(Serial Verb) construction from Figure and Ground perspective.
