By applying experimental method, the bolt stress and supporting mechanism is studied during the deformation process of a rock mass containing a weak interlayer. The force measuring bolt is installed manually and instr...By applying experimental method, the bolt stress and supporting mechanism is studied during the deformation process of a rock mass containing a weak interlayer. The force measuring bolt is installed manually and instrumented five pairs of symmetrical strain gauges. The experimental results show that the fully grouted bolt suffers tensile, compressive, bending and shear stress at the same time. The bolt stress evolution is closely related to the deformation stages of the rock mass which are very gradually varying stage, gradually varying stage at the pre-peak and suddenly varying stage at the post peak stage.The axial compressive stress in the bolt is mainly induced by the moment. Thus, in most cases the axial compressive stress is distributed on one side of the bolt. For axial stresses, induced by the axial force and the bending moment at the post-peak stage, three types of changing are observed, viz. increasingincreasing type, decreasing-increasing type and increasing-decreasing type. The stress characteristics of the bolt section in the weak interlayer are significantly different from those in the hard rock. The failure models of the anchored bolt are tensile failure and shear failure, respectively. The bolt not only provides constraints on the free surface of the rock mass, but also resists the axial and lateral loading by the bending moment. This study provides valuable guidelines for bolting support design and its safety assessment.展开更多
Large pressure equipment needs to be tested regularly to ensure safe operation;wall-climbing robots can carry the necessary tools to inspect spherical tanks,such as cameras and non-destructive testing equipment.Howeve...Large pressure equipment needs to be tested regularly to ensure safe operation;wall-climbing robots can carry the necessary tools to inspect spherical tanks,such as cameras and non-destructive testing equipment.However,a wall-climbing robot inside a spherical tank cannot be accurately positioned owing to the particularity of the spherical tank structure.This paper proposes a passive support and positioning mechanism fixed in a spherical tank to improve the adsorption capacity and positioning accuracy of the inspection robot.The main body of the mechanism was designed as a truss composed of carbon fiber telescopic rods and can work in spherical tanks with diameters of 4.6-15.7 m.The structural strength,stiffness,and stability of the mechanism are analyzed via force and deformation simulations.By constructing a mathematical model of the support and positioning mechanism,the influence of structural deformation on the supporting capacity is analyzed and calculated.The robot positioning method based on the support and positioning mechanism can effectively locate the robot inside a spherical tank.Experiments verified the support performance and robot positioning accuracy of the mechanism.This research proposes an auxiliary support and positioning mechanism for a detection robot inside a spherical tank,which can effectively improve the positioning accuracy of the robot and meet the robotic inspection requirements.展开更多
BACKGROUND Very little is known about the role of extracorporeal membrane oxygenation(ECMO)for the management of patients undergoing major aortic surgery with particular reference to aortic dissection.AIM To review th...BACKGROUND Very little is known about the role of extracorporeal membrane oxygenation(ECMO)for the management of patients undergoing major aortic surgery with particular reference to aortic dissection.AIM To review the available literature to determine if there was any evidence.METHODS A systematic literature search through PubMed and EMBASE was undertaken according to specific key words.RESULTS The search resulted in 29 publications relevant to the subject:1 brief communication,1 surgical technique report,1 invited commentary,1 retrospective case review,1 observational study,4 retrospective reviews,13 case reports and 7 conference abstracts.A total of 194 patients were included in these publications of whom 77 survived.CONCLUSION Although there is no compelling evidence for or against the use of ECMO in major aortic surgery or dissection,it is enough to justify its use in this patient population despite current adverse attitude.展开更多
This paper presents a distributed operating system modeled as an abstract machine that provides all the distributed processes with the same set of services.The kernel of our operating system supports ser- vices which ...This paper presents a distributed operating system modeled as an abstract machine that provides all the distributed processes with the same set of services.The kernel of our operating system supports ser- vices which are achieved by a remote procedure call on requests by parallel processes.Therefore,a scheme for solving the client-server relationship is required.In our system there are more than one cli- ents and,at least,a receive would he required for each.Similarly,there are more than one servers such that the send in a client should produce a message that can he received by every server. Consequently,a mechanism well suited for programming multiple-clients/single-server and sin- gle client/multiple-servers interactions is proposed.展开更多
BACKGROUND Coronavirus disease 2019(COVID-19)severity is classified as asymptomatic,mild,moderate,severe,and critical.Mild cases account for a large percentage of cases in the epidemic and typically exhibit a favorabl...BACKGROUND Coronavirus disease 2019(COVID-19)severity is classified as asymptomatic,mild,moderate,severe,and critical.Mild cases account for a large percentage of cases in the epidemic and typically exhibit a favorable prognosis.However,a 49%-67%mortality is noted in critical cases.No COVID-19-specific drug has been reported to date,and symptomatic and optimal supportive care,including oxygenation,anti-coinfection treatments,and ventilation,represent the mainstay of treatment for this disease,especially in critical patients.CASE SUMMARY In the above-mentioned context,we share our experience with the treatment of one critical COVID-19 case and review the relevant literature.CONCLUSION Timely tracheal intubation,reasonable mechanical ventilation support,appropriate anti-infection treatment,and early anticoagulation and immunity support are key factors in the successful treatment of this case.展开更多
Cardiogenic shock(CS)is a complex clinical syndrome with a high mortality rate.It can occur to due to multiple etiologies of cardiovascular disease and is phenotypically heterogeneous.Acute myocardial infarction-relat...Cardiogenic shock(CS)is a complex clinical syndrome with a high mortality rate.It can occur to due to multiple etiologies of cardiovascular disease and is phenotypically heterogeneous.Acute myocardial infarction-related CS(AMI-CS)has historically been the most prevalent cause,and thus,research and guidance have focused primarily on this.Recent data suggest that the burden of non-ischemic CS is increasing in the population of patents requiring intensive care admission.There is,however,a paucity of data and guidelines to inform the management of these patients who fall into two broad groups:those with existing heart failure and CS and those with no known history of heart failure who present with"de novo"CS.The use of temporary mechanical circulatory support(MCS)has expanded across all etiologies,despite its high cost,resource intensity,complication rates,and lack of high-quality outcome data.Herein,we discuss the currently available evidence on the role of MCS in the management of patients with de novo CS to include fulminant myocarditis,right ventricular(RV)failure,Takotsubo syndrome,post-partum cardiomyopathy,and CS due to valve lesions and other cardiomyopathies.展开更多
Extracorporeal membrane oxygenation has emerged as a viable alternative for stabilizing and improving critically ill patients in acute cardiovascular diseases.However,the weaning stage has been associated with a high ...Extracorporeal membrane oxygenation has emerged as a viable alternative for stabilizing and improving critically ill patients in acute cardiovascular diseases.However,the weaning stage has been associated with a high morbidity and mortality rate.This makes searching for strategies that reduce failure in this final process necessary.Implementing a new approach must be tried and included in our protocols,seeking the patient’s well-being at all times.In this article,the authors discuss their point of view regarding potential pharmacological alternatives and the mechanism of action involved,which could decrease the mortality associated with this therapeutic.展开更多
INTRODUCTION "End-stage heart disease" commonly refers to an irreversible stage of cardiac decompensation caused by a variety of pathologies that cannot be treated using conventional drugs or traditional surgical tr...INTRODUCTION "End-stage heart disease" commonly refers to an irreversible stage of cardiac decompensation caused by a variety of pathologies that cannot be treated using conventional drugs or traditional surgical treatments. The life expectancy of patients with end-stage heart disease ranges from 〈6 months to 1 year. Therapeutic strategies for end-stage heart disease patients are primarily based on three approaches: Internal medicine therapy, surgical therapy (heart transplantation), and multiple organ protection therapy via the core method of mechanical circulation assistance. Among these approaches, heart transplantation has become recognized as the most efl'ective treatment.展开更多
The philosophy of“publish or perish”has already been adopted as a yardstick by the vast majority of Chinese higher education institutions in their attempts to benchmark Western research universities in recent years,...The philosophy of“publish or perish”has already been adopted as a yardstick by the vast majority of Chinese higher education institutions in their attempts to benchmark Western research universities in recent years,which has led to increasing pressure on university teachers to produce research publications.This paper addresses this endemic issue in China’s teaching universities with particular reference to its impact on English teacher educators.It points out that this trend is a result of unrealistically benchmarking research universities in well-resourced Western countries and overlooking the nature of teaching universities,the nature of English teacher educators’professional commitments,and the practical constraints on China’s teaching institutions.It has given rise to a variety of problems which,unless addressed properly,may demoralize English teacher educators and impair the quality of both teaching and research.The paper argues that a fair perception of and attitude towards research and realistic expectations of English teacher educators’research outcomes are essential.Practical implications at macro-,meso-and micro-levels are provided with the aim of improving the status quo.展开更多
The prevalence of the risk factors and the risk of cardiac failure are both increasing in China.This might be the consequence of the changes of the life conditions(emigration to the urban areas,changes in the diet and...The prevalence of the risk factors and the risk of cardiac failure are both increasing in China.This might be the consequence of the changes of the life conditions(emigration to the urban areas,changes in the diet and life style,lack of physical exercise,etc.).The wide range of clinical presentations of cardiac failure(acute or chronic)and of therapeutic approaches(medical or surgical)makes necessary the integration within the same structure of the various experts involved in the diagnosis and the treatment of cardiac diseases.Technologic and human resources required to offer all the options represent a multifaceted commitment which should be focused optimally in dedicated centers.In these centers,collaboration should replace competition between the medical and the surgical cardiac specialists.Development of team work should permit to optimize the cost efficacy of the treatments.Most of all,such a structure will facilitate the translation of innovative therapies between the research centers and clinical facilities.展开更多
基金support of the National Basic Research 973 Program of China (No.2013CB036003)the National Natural Science Foundation of China (No.51374198)the National Natural Science Foundation young investigator grant program of China (Nos.51204163,51504247,and 51404255)
文摘By applying experimental method, the bolt stress and supporting mechanism is studied during the deformation process of a rock mass containing a weak interlayer. The force measuring bolt is installed manually and instrumented five pairs of symmetrical strain gauges. The experimental results show that the fully grouted bolt suffers tensile, compressive, bending and shear stress at the same time. The bolt stress evolution is closely related to the deformation stages of the rock mass which are very gradually varying stage, gradually varying stage at the pre-peak and suddenly varying stage at the post peak stage.The axial compressive stress in the bolt is mainly induced by the moment. Thus, in most cases the axial compressive stress is distributed on one side of the bolt. For axial stresses, induced by the axial force and the bending moment at the post-peak stage, three types of changing are observed, viz. increasingincreasing type, decreasing-increasing type and increasing-decreasing type. The stress characteristics of the bolt section in the weak interlayer are significantly different from those in the hard rock. The failure models of the anchored bolt are tensile failure and shear failure, respectively. The bolt not only provides constraints on the free surface of the rock mass, but also resists the axial and lateral loading by the bending moment. This study provides valuable guidelines for bolting support design and its safety assessment.
基金Supported by Jiangsu Major Research and Development(Social Development)Project of China(Grant No.BE2016802).
文摘Large pressure equipment needs to be tested regularly to ensure safe operation;wall-climbing robots can carry the necessary tools to inspect spherical tanks,such as cameras and non-destructive testing equipment.However,a wall-climbing robot inside a spherical tank cannot be accurately positioned owing to the particularity of the spherical tank structure.This paper proposes a passive support and positioning mechanism fixed in a spherical tank to improve the adsorption capacity and positioning accuracy of the inspection robot.The main body of the mechanism was designed as a truss composed of carbon fiber telescopic rods and can work in spherical tanks with diameters of 4.6-15.7 m.The structural strength,stiffness,and stability of the mechanism are analyzed via force and deformation simulations.By constructing a mathematical model of the support and positioning mechanism,the influence of structural deformation on the supporting capacity is analyzed and calculated.The robot positioning method based on the support and positioning mechanism can effectively locate the robot inside a spherical tank.Experiments verified the support performance and robot positioning accuracy of the mechanism.This research proposes an auxiliary support and positioning mechanism for a detection robot inside a spherical tank,which can effectively improve the positioning accuracy of the robot and meet the robotic inspection requirements.
文摘BACKGROUND Very little is known about the role of extracorporeal membrane oxygenation(ECMO)for the management of patients undergoing major aortic surgery with particular reference to aortic dissection.AIM To review the available literature to determine if there was any evidence.METHODS A systematic literature search through PubMed and EMBASE was undertaken according to specific key words.RESULTS The search resulted in 29 publications relevant to the subject:1 brief communication,1 surgical technique report,1 invited commentary,1 retrospective case review,1 observational study,4 retrospective reviews,13 case reports and 7 conference abstracts.A total of 194 patients were included in these publications of whom 77 survived.CONCLUSION Although there is no compelling evidence for or against the use of ECMO in major aortic surgery or dissection,it is enough to justify its use in this patient population despite current adverse attitude.
基金The project supported by National Natural Science Foundation of China.
文摘This paper presents a distributed operating system modeled as an abstract machine that provides all the distributed processes with the same set of services.The kernel of our operating system supports ser- vices which are achieved by a remote procedure call on requests by parallel processes.Therefore,a scheme for solving the client-server relationship is required.In our system there are more than one cli- ents and,at least,a receive would he required for each.Similarly,there are more than one servers such that the send in a client should produce a message that can he received by every server. Consequently,a mechanism well suited for programming multiple-clients/single-server and sin- gle client/multiple-servers interactions is proposed.
基金Supported by the Health and Family Planning Commission of Shenzhen Municipality,No.SZLY2018024and Sanming Project of Medicine in Shenzhen,No.SZSM201512031.
文摘BACKGROUND Coronavirus disease 2019(COVID-19)severity is classified as asymptomatic,mild,moderate,severe,and critical.Mild cases account for a large percentage of cases in the epidemic and typically exhibit a favorable prognosis.However,a 49%-67%mortality is noted in critical cases.No COVID-19-specific drug has been reported to date,and symptomatic and optimal supportive care,including oxygenation,anti-coinfection treatments,and ventilation,represent the mainstay of treatment for this disease,especially in critical patients.CASE SUMMARY In the above-mentioned context,we share our experience with the treatment of one critical COVID-19 case and review the relevant literature.CONCLUSION Timely tracheal intubation,reasonable mechanical ventilation support,appropriate anti-infection treatment,and early anticoagulation and immunity support are key factors in the successful treatment of this case.
文摘Cardiogenic shock(CS)is a complex clinical syndrome with a high mortality rate.It can occur to due to multiple etiologies of cardiovascular disease and is phenotypically heterogeneous.Acute myocardial infarction-related CS(AMI-CS)has historically been the most prevalent cause,and thus,research and guidance have focused primarily on this.Recent data suggest that the burden of non-ischemic CS is increasing in the population of patents requiring intensive care admission.There is,however,a paucity of data and guidelines to inform the management of these patients who fall into two broad groups:those with existing heart failure and CS and those with no known history of heart failure who present with"de novo"CS.The use of temporary mechanical circulatory support(MCS)has expanded across all etiologies,despite its high cost,resource intensity,complication rates,and lack of high-quality outcome data.Herein,we discuss the currently available evidence on the role of MCS in the management of patients with de novo CS to include fulminant myocarditis,right ventricular(RV)failure,Takotsubo syndrome,post-partum cardiomyopathy,and CS due to valve lesions and other cardiomyopathies.
文摘Extracorporeal membrane oxygenation has emerged as a viable alternative for stabilizing and improving critically ill patients in acute cardiovascular diseases.However,the weaning stage has been associated with a high morbidity and mortality rate.This makes searching for strategies that reduce failure in this final process necessary.Implementing a new approach must be tried and included in our protocols,seeking the patient’s well-being at all times.In this article,the authors discuss their point of view regarding potential pharmacological alternatives and the mechanism of action involved,which could decrease the mortality associated with this therapeutic.
基金Financial support and sponsorship This work was supported by a grant from National Natural Science Foundation of China (No. 81400290).
文摘INTRODUCTION "End-stage heart disease" commonly refers to an irreversible stage of cardiac decompensation caused by a variety of pathologies that cannot be treated using conventional drugs or traditional surgical treatments. The life expectancy of patients with end-stage heart disease ranges from 〈6 months to 1 year. Therapeutic strategies for end-stage heart disease patients are primarily based on three approaches: Internal medicine therapy, surgical therapy (heart transplantation), and multiple organ protection therapy via the core method of mechanical circulation assistance. Among these approaches, heart transplantation has become recognized as the most efl'ective treatment.
文摘The philosophy of“publish or perish”has already been adopted as a yardstick by the vast majority of Chinese higher education institutions in their attempts to benchmark Western research universities in recent years,which has led to increasing pressure on university teachers to produce research publications.This paper addresses this endemic issue in China’s teaching universities with particular reference to its impact on English teacher educators.It points out that this trend is a result of unrealistically benchmarking research universities in well-resourced Western countries and overlooking the nature of teaching universities,the nature of English teacher educators’professional commitments,and the practical constraints on China’s teaching institutions.It has given rise to a variety of problems which,unless addressed properly,may demoralize English teacher educators and impair the quality of both teaching and research.The paper argues that a fair perception of and attitude towards research and realistic expectations of English teacher educators’research outcomes are essential.Practical implications at macro-,meso-and micro-levels are provided with the aim of improving the status quo.
文摘The prevalence of the risk factors and the risk of cardiac failure are both increasing in China.This might be the consequence of the changes of the life conditions(emigration to the urban areas,changes in the diet and life style,lack of physical exercise,etc.).The wide range of clinical presentations of cardiac failure(acute or chronic)and of therapeutic approaches(medical or surgical)makes necessary the integration within the same structure of the various experts involved in the diagnosis and the treatment of cardiac diseases.Technologic and human resources required to offer all the options represent a multifaceted commitment which should be focused optimally in dedicated centers.In these centers,collaboration should replace competition between the medical and the surgical cardiac specialists.Development of team work should permit to optimize the cost efficacy of the treatments.Most of all,such a structure will facilitate the translation of innovative therapies between the research centers and clinical facilities.