Soft rock surrounding deep roadway has poor stability and long-term rheological effect. More and larger deformation problems of surrounding rock occur due to adverse supporting measures for such roadways, which not on...Soft rock surrounding deep roadway has poor stability and long-term rheological effect. More and larger deformation problems of surrounding rock occur due to adverse supporting measures for such roadways, which not only affects the engineering safety critically but also improves the maintenance costs. This paper takes the main rail roadway with severely deformation in China's Zaoquan coal mine as an example to study the long-term deformation tendency and damage zone by means of in-situ deformation monitoring and acoustic wave testing technique. A three-dimensional finite element model reflecting the engineering geological condition and initial design scheme is established by ABAQUS. Then, on the basis of field monitoring deformation data, the surrounding rock geotechnical and theological parameters of the roadway are obtained by back analysis. A combined supporting technology with U-shaped steel support and anchor-grouting is proposed for the surrounding soft rock. The numerical simulation of the combined supporting technology and in-situ deformation monitoring results show that the soft rock surrounding the roadway has been held effectively.展开更多
Municipal civil engineering is the key content of municipal construction,and the construction scale is usually large.The quality of the project plays an important role in the development of urban economy.Due to the ra...Municipal civil engineering is the key content of municipal construction,and the construction scale is usually large.The quality of the project plays an important role in the development of urban economy.Due to the rapid increase of high-rise buildings,skyscrapers and underground buildings,the construction technology of deep foundation pit support has gradually become an indispensable construction technology.Therefore,the selection of foundation pit support construction technology is crucial in ensuring that whether the foundation is firm and stable,and whether the subsequent construction activities can be carried out smoothly.In view of this,the article discusses the application of deep foundation pit support construction technology in municipal civil engineering,aiming to provide reference for subsequent projects.展开更多
[Objective] To analyze the key factor in agricultural technology diffusion- technology support, and to explore the method to quicken the diffusion of agricultural technology. [Method] The technology acquisition advant...[Objective] To analyze the key factor in agricultural technology diffusion- technology support, and to explore the method to quicken the diffusion of agricultural technology. [Method] The technology acquisition advantage of social network was il- lustrated by summarizing the status and characteristics of agricultural technology and technology supporting types in the process of agriculture technology diffusion. [Result] The multi-layer, complex, persistence, systematization features of agricultural technol- ogy require support and help of technology from surrounding social network to ulti- mately internalize the technology. [Conclusion] Using social networks for the technol- ogy support will be a powerful supplement to the system of agricultural technology diffusion.展开更多
For the engineering geology conditions of bad mine roadway roof and floor lithology in extremely weak cemented strata, the best section shape of the roadway is determined from the study of tunnel surrounding rock disp...For the engineering geology conditions of bad mine roadway roof and floor lithology in extremely weak cemented strata, the best section shape of the roadway is determined from the study of tunnel surrounding rock displacement, plastic zone and stress distribution in rectangular, circle arch and arch wall sections, respectively. Based on the mining depth and thickness of the coal seam, roadway support technology solutions with different buried depth and thickness of coal seam are proposed. Support schemes are amended and optimized in time through monitoring data of the deformation of roadway, roof separation, l-beam bracket, bolt and anchor cable force to ensure the long-term stability and security of the roadway surrounding rock and support structure. The monitoring results show that mine roadway support schemes for different buried depth and section can be adapted to the characteristics of ground pressure and deformation of the surrounding rock in different depth well, effectively control the roadway surrounding rock deformation and the floor heave and guarantee the safety of construction and basic stability of surrounding rock and support structure.展开更多
The paper introduces two typical 3G services:the mobile multimedia short message service and the streaming media service. The former is considered as a strong driving force to promote the development of 3G services an...The paper introduces two typical 3G services:the mobile multimedia short message service and the streaming media service. The former is considered as a strong driving force to promote the development of 3G services and applications.The latter is regarded as a typical service on future 3G networks.As supporting technologies of 3G services,open service architecture and open mobile architecture are also discussed.展开更多
When computers and communication devices are available everywhere in the future, the categories of communication will expand to cover not only the man-man and the man-machine, but also the machine-machine (M2M) commun...When computers and communication devices are available everywhere in the future, the categories of communication will expand to cover not only the man-man and the man-machine, but also the machine-machine (M2M) communication. Someday, the traffic generated by machines will greatly exceed those of man-machine and man-man applications. Large numbers of M2M applications will need various wireless networks to support them. This paper introduces the characteristics, advantages and disadvantages of the currently available various wireless network technologies, including WiFi, Bluetooth, ZigBee, passive RFID and the 802.15 standard networks.展开更多
With the advancement of education informatization,learning through the internet has become a very important approach.Existing teaching websites generally have problems such as low accuracy of information grouping and ...With the advancement of education informatization,learning through the internet has become a very important approach.Existing teaching websites generally have problems such as low accuracy of information grouping and obvious disconnection between the navigation system and content.Based on information architecture,a teaching website for early warning technical support specialty is designed in this paper from four aspects:content organization,identification,navigation,and interaction.The unification of information processing and information requirements is achieved using this method,which improves the quality of professional course construction for early warning technology support specialty.展开更多
As an important transportation hub in China,the traffic volume and driving speed are important aspects of expressways.Therefore,the protection requirements for roadbed side slopes are higher,and it is necessary to res...As an important transportation hub in China,the traffic volume and driving speed are important aspects of expressways.Therefore,the protection requirements for roadbed side slopes are higher,and it is necessary to resist rainwater erosion and other damages by protecting the side slopes.Therefore,it is necessary to adopt effective technical means of subgrade protection and support.This paper mainly summarizes the characteristics of highway subgrade slope protection construction and slope protection and support technologies.展开更多
In view of the disadvantages of vibration safety monitoring technology for offshore wind turbines,a new method is proposed to obtain deformation information of towering and dynamic targets in real-time by the ground-b...In view of the disadvantages of vibration safety monitoring technology for offshore wind turbines,a new method is proposed to obtain deformation information of towering and dynamic targets in real-time by the ground-based interferometric ra-dar(GBIR).First,the working principle and unique advantages of the GBIR system are introduced.Second,the offshore wind turbines in Rongcheng,Shandong Province are selected as the monitoring objects for vibration safety monitoring,and the GPRI-II portable radar interferometer is used for the health diagnosis of these wind turbines.Finally,the interpretation method and key processing flow of data acquisition are described in detail.This experiment shows that the GBIR system can accurately identify the millimeter-scale vibration deformation of offshore wind turbines and can quickly obtain overall time series deformation images of the target bodies,which demonstrate the high-precision deformation monitoring ability of the GBIR technology.The accuracy meets the requirements of wind turbine vibration monitoring,and the method is an effective spatial deformation monitoring means for high-rise and dynamic targets.This study is beneficial for the further enrichment and improvement of the technical system of wind turbine vibration safety monitoring in China.It also provides data and technical support for offshore power engineering management and control,health diagnosis,and disaster prevention and mitigation.展开更多
OBJECTIVE: A meta-analysis of published randomized controlled trials investigating the long- term effect of dexamethasone on the nervous system of preterm infants. DATA SOURCES: Online literature retrieval was condu...OBJECTIVE: A meta-analysis of published randomized controlled trials investigating the long- term effect of dexamethasone on the nervous system of preterm infants. DATA SOURCES: Online literature retrieval was conducted using The Cochrane Library (from January 1993 to June 2013), EMBASE (from January 1980 to June 2013), MEDLINE (from Janu- ary 1963 to June 2013), OVID (from January 1993 to June 2013), Springer (from January 1994 to June 2013) and Chinese Academic Journal Full-text Database (from January 1994 to June 2013). Key words were preterm infants and dexamethasone in English and Chinese. STUDY SELECTION: Selected studies were randomized controlled trials assessing the effect of intravenous dexamethasone in preterm infants. The quality of the included papers was evaluated and those without the development of the nervous system and animal experiments were exclud- ed. Quality assessment was performed through bias risk evaluation in accordance with Cochrane Handbook 5.1.0 software in the Cochrane Collaboration. The homogeneous studies were analyzed and compared using Revman 5.2.6 software, and then effect model was selected and analyzed. Those papers failed to be included in the meta-analysis were subjected to descriptive analysis. MAIN OUTCOME MEASURES: Nervous system injury in preterm infants. RESULTS: Ten randomized controlled trials were screened, involving 1,038 subjects. Among them 512 cases received dexamethasone treatment while 526 cases served as placebo control group and blank control group. Meta-analysis results showed that the incidence of cerebral palsy, visual im- pairment and hearing loss in preterm infants after dexamethasone treatment within 7 days after birth was similar to that in the control group (RR = 1.47, 95%CI: 0.97-2.21; RR = 1.46, 95%CI: 0.97-2.20; RR = 0.80, 95%CI: 0.54-1.18; P 〉 0.05), but intelligence quotient was significantly de- creased compared with the control group (MD = -3.55, 95%CI: -6.59 to -0.51; P = 0.02). Prete rm infants treated with dexamethasone 7 days after birth demonstrated an incidence of cerebral palsy and visual impairment, and changes in intelligence quotient similar to those in the control group (RR = 1.26, 95%CI: 0.89-1.79; RR = 1.37, 95%CI: 0.73-2.59; RR = 0.53, 95%CI: 0.32-0.89; RR = 1.66, 95%CI: -4.7 to 8.01; P 〉 0.05). However, the incidence of hearing loss was significantly increased compared with that in the control group (RR = 0.53, 95%CI: 0.32-0.89; P = 0.02). CONCLUSION: Dexamethasone may affect the intelligence of preterm infants in the early stages after birth, but may lead to hearing impairment at later stages after birth. More reliable conclusions should be made through large-size, multi-center, well-designed randomized controlled trials.展开更多
The field of information systems has historically suffered from a pre-dominance of behavioral approaches. As a result, it is not surprising that in spite of decades of research, dozens of conferences and journals and ...The field of information systems has historically suffered from a pre-dominance of behavioral approaches. As a result, it is not surprising that in spite of decades of research, dozens of conferences and journals and thousands of researchers, very few breakthroughs have been achieved. This paper advocates a technical approach that focuses on improving existing systems in organizations by viewing them from the point of roles i.e. functions fulfilled by IS in organizations. These are understood as: 1) supporting operations, 2) providing information, 3) supporting decision making, 4) providing knowledge, 5) supporting knowledge and clerical work, and 6) supporting organizational design. It is generally agreed that the field’s understanding of fulfilling roles “1”, “2”, “3” and “6” is mature while understanding of areas “3” (for unstructured decisions), “4”, and “5” are still incomplete. The challenges in these areas are difficult problems that we refer to as grand challenges and discuss in this paper.展开更多
At the first gathering of its kind on the role of science in implementing the Sendai Framework for Disaster Risk Reduction 2015–2030,over 750 scientists,policymakers,business people,and practitioners met in Geneva fr...At the first gathering of its kind on the role of science in implementing the Sendai Framework for Disaster Risk Reduction 2015–2030,over 750 scientists,policymakers,business people,and practitioners met in Geneva from January 27–29,2016.The UNISDR Science and Technology Conference on the Implementation of the Sendai Framework for Disaster Risk Reduction 2015–2030 fea-展开更多
Near infrared spectroscopy (NIR) is now probably the most popular process analytical technology (PAT) for pharmaceutical and some other industries. However, unlike mid-IR, NIR is known to have difficulties in moni...Near infrared spectroscopy (NIR) is now probably the most popular process analytical technology (PAT) for pharmaceutical and some other industries. However, unlike mid-IR, NIR is known to have difficulties in monitoring crystallization or precipitation processes because the existence of solids could cause distortion of the spectra. This phenomenon, seen as unfavorable previously, is however an indication that NIR spectra contain rich information about both solids and liquids, giving the possibility of using the same instrument for multiple property characterization. In this study, transflectance NIR calibration data was obtained using solutions and slurries of varied solution concentration, particle size, solid concentration and temperature. The data was used to build calibration models for prediction of the multiple properties of both phases. Predictive models were developed for this challenging application using an approach that combines genetic algorithm (GA) and support vector machine (SVM). GA is used for wavelength selection and SVM for mode building. The new GA-SVM approach is shown to outperform other methods including GA-PLS (partial least squares) and traditional SVM. NIR is thus successfully applied to monitoring seeded and unseeded cooling crystallization processes of L-glutamic acid.展开更多
The Qingcheng oilfield,the largest shale oil field in China,was discovered in 2019 in source rock of Chang 7 Member of Mesozoic Yanchang Formation,Changqing Oilfield in Ordos Basin,with newly increased proven geologic...The Qingcheng oilfield,the largest shale oil field in China,was discovered in 2019 in source rock of Chang 7 Member of Mesozoic Yanchang Formation,Changqing Oilfield in Ordos Basin,with newly increased proven geological reserves of 358 million tons,predicted geological reserves of 693 million tons,and a total of 1.051 billion tons of shale oil resources.This achieves a historic breakthrough in exploration of shale oil in Chang 7 Member.In recent years,focusing on key issues,such as whether there develop sweet spots in source rock,whether commercial oil production capacity can be formed,and whether scale-effective development can be achieved,studies about geological conditions for shale oil accumulation have been continuously carried out,key supporting technologies have been developed,and a series of theoretical innovations and technological breakthroughs have been achieved in oil exploration in source rocks.The results indicate that shale oil accumulation in Chang 7 Member is controlled by following factors.Firstly,lacustrine black shale,dark mudstone and other high-quality source rocks lay a material foundation for shale oil formation.Secondly,sandy deposits intercalated within black shale and dark mudstones are exploration sweet spots,and sandbody combination types are controlled by morphology of bottom of the lacustrine basin.Thirdly,reservoir properties are good due to development of micro-nano pore throats.Finally,reservoirs with high oil saturation and high gas-oil ratio are formed due to high-intensity oil charging in source rock.Effective matching of multiple factors is a key for shale oil accumulation in Chang 7 Member in Ordos Basin.Through innovation of key supporting technologies,exploration and development technologies for shale oil are developed,and substantial breakthrough on exploration and development of shale oil is realized.The first application of logging-seismic combination technology in loess plateau improves significantly quality of 3D seismic data,which effectively guides prediction of sandy sweet spots.Three-quality well logging technology is used for further evaluation of geological and engineering sweet spots of shale oil.With volumetric fracturing technology based on precise segmentation of long horizontal wells,initial daily oil production of individual well is increased from previously 10 tons to more than 18 tons.The exploration breakthrough in source rocks in Chang 7 Member in Qingcheng oilfield provides an important resource base for the second accelerated development of Changqing Oilfield.It is predicated that oil production from shale in Chang 7 Member in Qingcheng oilfield will reach three million tons in 2022 and five million tons in 2025.展开更多
基金Projects(51409154,41772299)supported by the National Natural Science Foundation of ChinaProject(J16LG03)supported by the Shandong Province Higher Educational Science and Technology Program,China+1 种基金Projects(2015JQJH106,2014TDJH103)supported by the SDUST Research Fund,ChinaProject(201630576)supported by the Tai’an Scientific and Technologic Development Project,China
文摘Soft rock surrounding deep roadway has poor stability and long-term rheological effect. More and larger deformation problems of surrounding rock occur due to adverse supporting measures for such roadways, which not only affects the engineering safety critically but also improves the maintenance costs. This paper takes the main rail roadway with severely deformation in China's Zaoquan coal mine as an example to study the long-term deformation tendency and damage zone by means of in-situ deformation monitoring and acoustic wave testing technique. A three-dimensional finite element model reflecting the engineering geological condition and initial design scheme is established by ABAQUS. Then, on the basis of field monitoring deformation data, the surrounding rock geotechnical and theological parameters of the roadway are obtained by back analysis. A combined supporting technology with U-shaped steel support and anchor-grouting is proposed for the surrounding soft rock. The numerical simulation of the combined supporting technology and in-situ deformation monitoring results show that the soft rock surrounding the roadway has been held effectively.
文摘Municipal civil engineering is the key content of municipal construction,and the construction scale is usually large.The quality of the project plays an important role in the development of urban economy.Due to the rapid increase of high-rise buildings,skyscrapers and underground buildings,the construction technology of deep foundation pit support has gradually become an indispensable construction technology.Therefore,the selection of foundation pit support construction technology is crucial in ensuring that whether the foundation is firm and stable,and whether the subsequent construction activities can be carried out smoothly.In view of this,the article discusses the application of deep foundation pit support construction technology in municipal civil engineering,aiming to provide reference for subsequent projects.
基金Supported by the National Social Science Foundation of China:the Sociological Study on the Technology Adoption Behaviors of Farmers(08BSH049)~~
文摘[Objective] To analyze the key factor in agricultural technology diffusion- technology support, and to explore the method to quicken the diffusion of agricultural technology. [Method] The technology acquisition advantage of social network was il- lustrated by summarizing the status and characteristics of agricultural technology and technology supporting types in the process of agriculture technology diffusion. [Result] The multi-layer, complex, persistence, systematization features of agricultural technol- ogy require support and help of technology from surrounding social network to ulti- mately internalize the technology. [Conclusion] Using social networks for the technol- ogy support will be a powerful supplement to the system of agricultural technology diffusion.
基金Financial support for this work, provided by the Major Program of the National Natural Science Foundation of China (Nos. 51174196 and 51204168)the Program for New Century Excellent Talents in University by Ministry of Education of China (No. NCET-07-0519)
文摘For the engineering geology conditions of bad mine roadway roof and floor lithology in extremely weak cemented strata, the best section shape of the roadway is determined from the study of tunnel surrounding rock displacement, plastic zone and stress distribution in rectangular, circle arch and arch wall sections, respectively. Based on the mining depth and thickness of the coal seam, roadway support technology solutions with different buried depth and thickness of coal seam are proposed. Support schemes are amended and optimized in time through monitoring data of the deformation of roadway, roof separation, l-beam bracket, bolt and anchor cable force to ensure the long-term stability and security of the roadway surrounding rock and support structure. The monitoring results show that mine roadway support schemes for different buried depth and section can be adapted to the characteristics of ground pressure and deformation of the surrounding rock in different depth well, effectively control the roadway surrounding rock deformation and the floor heave and guarantee the safety of construction and basic stability of surrounding rock and support structure.
文摘The paper introduces two typical 3G services:the mobile multimedia short message service and the streaming media service. The former is considered as a strong driving force to promote the development of 3G services and applications.The latter is regarded as a typical service on future 3G networks.As supporting technologies of 3G services,open service architecture and open mobile architecture are also discussed.
文摘When computers and communication devices are available everywhere in the future, the categories of communication will expand to cover not only the man-man and the man-machine, but also the machine-machine (M2M) communication. Someday, the traffic generated by machines will greatly exceed those of man-machine and man-man applications. Large numbers of M2M applications will need various wireless networks to support them. This paper introduces the characteristics, advantages and disadvantages of the currently available various wireless network technologies, including WiFi, Bluetooth, ZigBee, passive RFID and the 802.15 standard networks.
基金This research was supported by the College HOUJI Foundation Project(Grant Number:HJGC2021015).
文摘With the advancement of education informatization,learning through the internet has become a very important approach.Existing teaching websites generally have problems such as low accuracy of information grouping and obvious disconnection between the navigation system and content.Based on information architecture,a teaching website for early warning technical support specialty is designed in this paper from four aspects:content organization,identification,navigation,and interaction.The unification of information processing and information requirements is achieved using this method,which improves the quality of professional course construction for early warning technology support specialty.
文摘As an important transportation hub in China,the traffic volume and driving speed are important aspects of expressways.Therefore,the protection requirements for roadbed side slopes are higher,and it is necessary to resist rainwater erosion and other damages by protecting the side slopes.Therefore,it is necessary to adopt effective technical means of subgrade protection and support.This paper mainly summarizes the characteristics of highway subgrade slope protection construction and slope protection and support technologies.
基金This research was funded by the Public Science and Technology Research Funds Projects of Ocean(No.201405028)the Scientific Research Project of Shandong Electric Power Engineering Consulting Institute Co.,Ltd.(No.2020-059).
文摘In view of the disadvantages of vibration safety monitoring technology for offshore wind turbines,a new method is proposed to obtain deformation information of towering and dynamic targets in real-time by the ground-based interferometric ra-dar(GBIR).First,the working principle and unique advantages of the GBIR system are introduced.Second,the offshore wind turbines in Rongcheng,Shandong Province are selected as the monitoring objects for vibration safety monitoring,and the GPRI-II portable radar interferometer is used for the health diagnosis of these wind turbines.Finally,the interpretation method and key processing flow of data acquisition are described in detail.This experiment shows that the GBIR system can accurately identify the millimeter-scale vibration deformation of offshore wind turbines and can quickly obtain overall time series deformation images of the target bodies,which demonstrate the high-precision deformation monitoring ability of the GBIR technology.The accuracy meets the requirements of wind turbine vibration monitoring,and the method is an effective spatial deformation monitoring means for high-rise and dynamic targets.This study is beneficial for the further enrichment and improvement of the technical system of wind turbine vibration safety monitoring in China.It also provides data and technical support for offshore power engineering management and control,health diagnosis,and disaster prevention and mitigation.
基金supported by the Science and Technology Plan Program of Hunan Province,No.2011SK3234
文摘OBJECTIVE: A meta-analysis of published randomized controlled trials investigating the long- term effect of dexamethasone on the nervous system of preterm infants. DATA SOURCES: Online literature retrieval was conducted using The Cochrane Library (from January 1993 to June 2013), EMBASE (from January 1980 to June 2013), MEDLINE (from Janu- ary 1963 to June 2013), OVID (from January 1993 to June 2013), Springer (from January 1994 to June 2013) and Chinese Academic Journal Full-text Database (from January 1994 to June 2013). Key words were preterm infants and dexamethasone in English and Chinese. STUDY SELECTION: Selected studies were randomized controlled trials assessing the effect of intravenous dexamethasone in preterm infants. The quality of the included papers was evaluated and those without the development of the nervous system and animal experiments were exclud- ed. Quality assessment was performed through bias risk evaluation in accordance with Cochrane Handbook 5.1.0 software in the Cochrane Collaboration. The homogeneous studies were analyzed and compared using Revman 5.2.6 software, and then effect model was selected and analyzed. Those papers failed to be included in the meta-analysis were subjected to descriptive analysis. MAIN OUTCOME MEASURES: Nervous system injury in preterm infants. RESULTS: Ten randomized controlled trials were screened, involving 1,038 subjects. Among them 512 cases received dexamethasone treatment while 526 cases served as placebo control group and blank control group. Meta-analysis results showed that the incidence of cerebral palsy, visual im- pairment and hearing loss in preterm infants after dexamethasone treatment within 7 days after birth was similar to that in the control group (RR = 1.47, 95%CI: 0.97-2.21; RR = 1.46, 95%CI: 0.97-2.20; RR = 0.80, 95%CI: 0.54-1.18; P 〉 0.05), but intelligence quotient was significantly de- creased compared with the control group (MD = -3.55, 95%CI: -6.59 to -0.51; P = 0.02). Prete rm infants treated with dexamethasone 7 days after birth demonstrated an incidence of cerebral palsy and visual impairment, and changes in intelligence quotient similar to those in the control group (RR = 1.26, 95%CI: 0.89-1.79; RR = 1.37, 95%CI: 0.73-2.59; RR = 0.53, 95%CI: 0.32-0.89; RR = 1.66, 95%CI: -4.7 to 8.01; P 〉 0.05). However, the incidence of hearing loss was significantly increased compared with that in the control group (RR = 0.53, 95%CI: 0.32-0.89; P = 0.02). CONCLUSION: Dexamethasone may affect the intelligence of preterm infants in the early stages after birth, but may lead to hearing impairment at later stages after birth. More reliable conclusions should be made through large-size, multi-center, well-designed randomized controlled trials.
文摘The field of information systems has historically suffered from a pre-dominance of behavioral approaches. As a result, it is not surprising that in spite of decades of research, dozens of conferences and journals and thousands of researchers, very few breakthroughs have been achieved. This paper advocates a technical approach that focuses on improving existing systems in organizations by viewing them from the point of roles i.e. functions fulfilled by IS in organizations. These are understood as: 1) supporting operations, 2) providing information, 3) supporting decision making, 4) providing knowledge, 5) supporting knowledge and clerical work, and 6) supporting organizational design. It is generally agreed that the field’s understanding of fulfilling roles “1”, “2”, “3” and “6” is mature while understanding of areas “3” (for unstructured decisions), “4”, and “5” are still incomplete. The challenges in these areas are difficult problems that we refer to as grand challenges and discuss in this paper.
文摘At the first gathering of its kind on the role of science in implementing the Sendai Framework for Disaster Risk Reduction 2015–2030,over 750 scientists,policymakers,business people,and practitioners met in Geneva from January 27–29,2016.The UNISDR Science and Technology Conference on the Implementation of the Sendai Framework for Disaster Risk Reduction 2015–2030 fea-
基金UK Engineering and Physical Sciences Research Council for funding the research (EPSRCGrant Reference: EP/C001788/1)
文摘Near infrared spectroscopy (NIR) is now probably the most popular process analytical technology (PAT) for pharmaceutical and some other industries. However, unlike mid-IR, NIR is known to have difficulties in monitoring crystallization or precipitation processes because the existence of solids could cause distortion of the spectra. This phenomenon, seen as unfavorable previously, is however an indication that NIR spectra contain rich information about both solids and liquids, giving the possibility of using the same instrument for multiple property characterization. In this study, transflectance NIR calibration data was obtained using solutions and slurries of varied solution concentration, particle size, solid concentration and temperature. The data was used to build calibration models for prediction of the multiple properties of both phases. Predictive models were developed for this challenging application using an approach that combines genetic algorithm (GA) and support vector machine (SVM). GA is used for wavelength selection and SVM for mode building. The new GA-SVM approach is shown to outperform other methods including GA-PLS (partial least squares) and traditional SVM. NIR is thus successfully applied to monitoring seeded and unseeded cooling crystallization processes of L-glutamic acid.
基金supported by the National Research Council of Science and Technology Major Project of China(No.2016ZX05050,No.2017ZX05001002)National Key Basic Research Project of China(973 Program)(No.2014CB239003).
文摘The Qingcheng oilfield,the largest shale oil field in China,was discovered in 2019 in source rock of Chang 7 Member of Mesozoic Yanchang Formation,Changqing Oilfield in Ordos Basin,with newly increased proven geological reserves of 358 million tons,predicted geological reserves of 693 million tons,and a total of 1.051 billion tons of shale oil resources.This achieves a historic breakthrough in exploration of shale oil in Chang 7 Member.In recent years,focusing on key issues,such as whether there develop sweet spots in source rock,whether commercial oil production capacity can be formed,and whether scale-effective development can be achieved,studies about geological conditions for shale oil accumulation have been continuously carried out,key supporting technologies have been developed,and a series of theoretical innovations and technological breakthroughs have been achieved in oil exploration in source rocks.The results indicate that shale oil accumulation in Chang 7 Member is controlled by following factors.Firstly,lacustrine black shale,dark mudstone and other high-quality source rocks lay a material foundation for shale oil formation.Secondly,sandy deposits intercalated within black shale and dark mudstones are exploration sweet spots,and sandbody combination types are controlled by morphology of bottom of the lacustrine basin.Thirdly,reservoir properties are good due to development of micro-nano pore throats.Finally,reservoirs with high oil saturation and high gas-oil ratio are formed due to high-intensity oil charging in source rock.Effective matching of multiple factors is a key for shale oil accumulation in Chang 7 Member in Ordos Basin.Through innovation of key supporting technologies,exploration and development technologies for shale oil are developed,and substantial breakthrough on exploration and development of shale oil is realized.The first application of logging-seismic combination technology in loess plateau improves significantly quality of 3D seismic data,which effectively guides prediction of sandy sweet spots.Three-quality well logging technology is used for further evaluation of geological and engineering sweet spots of shale oil.With volumetric fracturing technology based on precise segmentation of long horizontal wells,initial daily oil production of individual well is increased from previously 10 tons to more than 18 tons.The exploration breakthrough in source rocks in Chang 7 Member in Qingcheng oilfield provides an important resource base for the second accelerated development of Changqing Oilfield.It is predicated that oil production from shale in Chang 7 Member in Qingcheng oilfield will reach three million tons in 2022 and five million tons in 2025.